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| 1 | 全球动脉粥样硬化血栓形成门诊患者中心血管危险因素的患病率、认知和治疗显示文摘Context: Atherothrombosis is the leading cause of cardiovascular morbidity and mortality around the globe. To date, no single international database has characterized the atherosclerosis risk factor profile or treatment intensity of individuals with atherothrombosis. Objective: To determine whether atherosclerosis risk factor prevalence and treatment would demonstrate comparable patterns in many countries around the world. Design, Setting, and Participants: The Reduction of Atherothrombosis for Continued Health(REACH) Registry collected data on atherosclerosis risk factors and treatment. A total of 67 888 patients aged 45 years or older from 5473 physician practices in 44 countries had either established arterial disease(coronary artery disease[CAD], n=40 258; cerebrovascular disease, n=18843; peripheral arterial disease, n=8273) or 3 or more risk factors for atherothrombosis(n=12 389) between 2003 and 2004. Main Outcome Measures: Baseline prevalence of atherosclerosis risk factors, medication use, and degree of risk factor control. Results: Atherothrombotic patients throughout the world had similar risk factor profiles: a high proportion with hypertension(81.8% ), hypercholesterolemia(72.4% ), and diabetes(44.3% ). The prevalence of overweight(39.8% ), obesity(26.6% ), and morbid obesity(3.6% ) were similar in most geographic locales, but was highest in North America(overweight: 37.1% , obese: 36.5% , and morbidly obese: 5.8% ; P< .001 vs other regions). Patients were generally undertreated with statins(69.4% overall; range: 56.4% for cerebrovascular disease to 76.2% for CAD), antiplatelet agents(78.6% overall; range: 53.9% for ≥ 3 risk factors to 85.6% for CAD), and other evidence-based risk reduction therapies. Current tobacco use in patients with established vascular disease was substantial(14.4% ). Undertreated hypertension(50.0% with elevated blood pressure at baseline), undiagnosed hyperglycemia(4.9% ), and impaired fasting glucose(36.5% in those not known to be diabetic) were common. Among those with symptomatic atherothrombosis, 15.9% had symptomatic polyvascular disease. Conclusion: This large, international, contemporary database shows that classic cardiovascular risk factors are consistent and common but are largely undertreated and undercontrolled in many regions of the world. | Bhatt D.L Gabriel Steg P Magnus Ohman E. 黄浙勇 | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006，2，5： | 5 |
| 2 | The search for new risk factors for coronary heart disease: occupational therapy for epidemiologists 显示文摘 | Beaglehole R Magnus P | 2002 | Int J Epi- demiol2002，31，6： | 1 |
| 3 | Operational factors affecting enhanced biological phosphorus removal at the wastewater treatment plant in Helsinghorg Sweden显示文摘 | Jonsson K Johansson P Magnus C | 1996 | Water Science end Technology1996，34，3： | 1 |
| 4 | Syudies of the pa-thophysiological in frontotemporal ementia by proteome analysis of CSF proteins显示文摘 | Davidsson P Magnus S Niels A | 2002 | Molecular brain research2002，109，： | 1 |
| 5 | High gravity brewing: nutrient enhanced production of high concentrations of ethanol by brewing yeast显示文摘 | CASEY G P MAGNUS C A INGLEDEW W M | 1983 | Biotechnol Lett1983，5，6： | 1 |
| 6 | The search for new risk factors for coronary heart disease:occupational therapy for epidemiologists? 显示文摘 | Beaglehole R Magnus P | 2002 | Int J Epidemiol2002，31，6： | 1 |
| 7 | Comparison of free and bound iodine and iodide species as a function of the dilution of three commercial povidone-iodine formulations and their microbicidal activity显示文摘 | Magnus A Atemnkeng Jacqueline P V | 2006 | In J Pharm2006，317，： | 1 |
| 8 | Operational factors affecting enhanced biological phosphorus removal at the wastewater treatment plant in Helsingborg,Sweden显示文摘 | Jonsson K Johansson P Magnus Christensson | 1996 | Wat Sci Tech1996，34，3： | 1 |
| 9 | The familial risk of endometriosis显示文摘 | Moen MH Magnus P | 1993 | Gynecol Scand1993，72，7： | 1 |
| 10 | Baby swimming increases the risk of recurrent respiratory tract infections and otitis media显示文摘 | Nystad W Nja F Magnus P | 2003 | Acta Paediatr2003，92，8： | 1 |
| 11 | Deterioration of the seven- teenth century warship Vasa by internal formation of sulphuric acid 显示文摘 | Magnus S Farideh J Ingmar P | 2002 | Nature2002，415，： | 1 |
| 12 | Toward a precise definition of interstitial cystitis: further evidence of differences in classic and nonulcer disease显示文摘 | Ralph P Magnus F | 2002 | JUrol2002，167，6： | 1 |
| 13 | Risk of childhood asthma and allergic rhinitis in relation to pregnancy complications显示文摘 | Nafstad P Magnus P Jaakkola JJ | 2000 | J Allergy Clin Immunol2000，106，5： | 1 |
| 14 | Intermittent hypoxia-activated cyclooxygenase pathway: role in atherosclerosis显示文摘 | Elodie Gautier-Veyret Claire Arnaud Magnus B?ck Jean-Louis Pépin Marcelo H. Petri Jean-Philippe Baguet Renaud Tamisier Patrick Lévy Fran?oise Stanke-Labesque | 2013 | European Respiratory Journal2013，，： | 1 |
| 15 | Models for a hypothetical mechanism of action of the anticancer agent vinblastine显示文摘 | Magnus P Ladlow M Elliot J | 1987 | Am Chem Soc1987，109，25： | 1 |
| 16 | Epidemiology and heritability of astigmatism in norwegian twins:an analysis of self-reported data显示文摘 | Grjibovski AM Magnus P Midelfart A | 2006 | Ophthalmic Epidemiol2006，13，4： | 1 |
| 17 | Stereospecific dicobalt octacarbonyl mediated enyne cyclization for the synthesis of the cytotoxic sesquiterpene (±)-Quadrone显示文摘 | Magnus P Principe L M Slater M J | 1987 | J Org Chem1987，52，8： | 1 |
| 18 | Exposure to pets and atopy-related diseases in the first 4 years of life 显示文摘 | Nafstad P Magnus P Gaarder PI | 2001 | Allergy2001，56，4： | 1 |
| 19 | The search for new risk factors for coronary heart disease:occupational therapy for epidemiologists显示文摘 | Magnus P | 2002 | Int J Epidemiol2002，31，6： | 1 |
| 20 | Deterioration of the seven- teenth century warship vasa by Internal formation of sulphuric acid 显示文摘 | Magnus S Farideh J Ingmar P | 2002 | Nature2002，415，： | 1 |
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