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| 1 | Effects of glycaemic management on diabetic kidney disease显示文摘Hyperglycaemia contributes to the onset and progression of diabetic kidney disease(DKD). Observational studies have not consistently demonstrated a glucose threshold, in terms of HbA1c levels, for the onset of DKD. Tight glucose control has clearly been shown to reduce the incidence of micro-or macroalbuminuria. However, evidence is now also emerging to suggest that intensive glucose control can slow glomerular filtration rate loss and possibly progression to end stage kidney disease. Achieving tight glucose control needs to be balanced against the increasing appreciation that glucose targets for the prevention of diabetes related complications need be individualised for each patient. Recently, empagliflozin which is an oral glucose lowering agent of the sodium glucose cotransporter-2 inhibitor class has been shown to have renal protective effects. However, the magnitude of empagliflozin's reno-protective properties are over and above that expected from its glucose lowering effects and most likely largely result from mechanisms involving alterations in intra-renal haemodynamics. Liraglutide and semaglutide, both injectable glucose lowering agents which are analogues of human glucagon like peptide-1 have also been shown to reduce progression to macroalbuminuria through mechanisms that remain to be fully elucidated. Here we review the evidence from observational and interventional studies that link good glucose control with improved renal outcomes. We also briefly review the potential reno-protective effects ofnewer glucose lowering agents. | Richard J MacIsaac George Jerums Elif I Ekinci | 2017 | World Journal of Diabetes2017，8，5： | 6 |
| 2 | β-葡聚糖酵母对肉鸡生长性能的影响显示文摘1引言通常在肉鸡日粮中添加低浓度(亚治疗剂量)的抗生素以求能促进肉鸡的生长、提高其饲料效率、减少肉鸡个体间的差异、预防疾病和提高碳水化合物和脂肪的消化。它们的应用已使肉鸡养殖业能够大量生产价廉、味美的鸡肉产品,同时通过降低疾病的发病率可提高肉鸡的健康和福利。近年来,人医和兽医上细菌耐药性问题日益加重,加之消费者对肉产品中兽药残留的担忧也日趋增强。 | 袁楷(译) 夏雨(校) B. Rathgeber K. Budgell J. MacIsaac M.Mirza | 2008 | 国外畜牧学(猪与禽)2008，28，3： | 3 |
| 3 | 利用测评工具改进课堂教学——以物理学科为例显示文摘一直以来,一些由科学、数学和教育工作者组成的专业团体,呼吁要大力改革科学与数学教学。他们在报告中批评美国的科学和数学教学前后不连贯、内容过度重复、主题不突出,用他们的话说就是“泛而不精”。 | Dan MacIsaac Kathleen Falconer 吴维宁 | 2013 | 教育测量与评价(理论版)2013，，2： | 2 |
| 4 | Does saltwater flushing reduce viability of diapausing eggs in ship ballast sediment显示文摘 | BAILEY S A NANDAKUMAR K MACISAAC H J | 2006 | Diversity and Distributions2006，12，3： | 1 |
| 5 | Estimating glomerularfiltration rate in diabetes:a comparison of cystatin-C-and creatinine-based methods显示文摘 | Macisaac RJ Tsalamandris C Thomas MC | | 0，，7： | 1 |
| 6 | Lowering of Proteinuria in Response to Antihypertensive Therapy Predicts Improved Renal Function in Late but Not in Early Diabetic Nephropathy: A Pooled Analysis显示文摘 | Jerums George Panagiotopoulos Sianna Premaratne Erosha Power David A Macisaac Richard J | 2008 | American Journal of Nephrology2008，，4： | 1 |
| 7 | Estimating glomerular filtration rate in diabetes using serum cystatin C 显示文摘 | Macisaac R J Premaratne E Jerums G | 2011 | Clin Biochem Rev2011，32，2： | 1 |
| 8 | The Chronic KidneyDisease - Epidemiology Collaboration ( CKD - EPI) equation doesnot improve the underestimation of Glomerular Filtration Rate(GFR) in people with diabetes and preserved renal function显示文摘 | Macisaac RJ Ekinci El Premaratne E | 2015 | BMC Nephrol2015，16，1： | 1 |
| 9 | Estimating glomerular filtration rate in diabetes: a comparison of cystatin- C-and creatinine-based methods 显示文摘 | Macisaac RJ Tsalamandris C Thomas MC | 2006 | Diabetologia2006，49，7： | 1 |
| 10 | Epidemiology of sepsis in Victoria, Australia 显示文摘 | Sundararajan V Macisaac CM Presneill JJ | 2005 | Crit Care Med2005，33，1： | 1 |
| 11 | Serial easurements of cystatin C are more accurate than creatinine-hased methods in detecting declining renal function in type 1 diabetes 显示文摘 | Premaratne E Macisaac R J Finch S | 2008 | Diabetes Care2008，31，5： | 1 |
| 12 | Influence of age on the presentation and outcome of acidotic and hyperosmolar diabetic emergencies显示文摘 | Macisaac RJ Lee LY McNeil KJ | 2002 | Intern Med2002，32，8： | 1 |
| 13 | Routine training is not enough:structure d training in family planning and abortion improves residents' competency scores and intentions to provide abortion after grad uation more than ad hoc training显示文摘 | Macisaac L Vickery Z | 2012 | Contraception2012，85，3： | 1 |
| 14 | Renal hyperfiltration in type 2 diabetes: effect of age-related decline in glomerular filtration rate显示文摘 | Premarame E Macisaac R J Tsalamandris C | 2005 | Diabetologia2005，48，12： | 1 |
| 15 | Serial easurements ofcystatin C are more accurate than creatinine-based methods indetecting declining renal function in type 1 diabetes显示文摘 | Premaratne E Macisaac RJ Finch S | 2008 | DiabetesCare2008，31，5： | 1 |
| 16 | Es- timating glomerularfiltration rate in diabetes: a com- parison of cystatin-C and creatinine-based methods显示文摘 | Macisaac RJ Tsalamandris C Thomas MC | 2006 | Diabetologia2006，49，12： | 1 |
| 17 | Nonalbumi-nuric renal insufficiency in type 2 diabetes显示文摘 | MacIsaac RJ Tsalamandris C Panagiotopoulos S | 2004 | Diabetes Care2004，27，1： | 1 |
| 18 | Influence of age on the presentation and outcome of acidotic and hyperosmolar diabetic emergencies显示文摘 | MACISAAC RJ LEE LY MCNEIL KJ | 2002 | J Intern Med2002，32，8： | 1 |
| 19 | Thermodynamic models for pipelinegas turbine diagnostics 显示文摘 | Saravanamuttoo Macisaac | 1983 | Journal of Engineering for Power1983，，105： | 1 |
| 20 | Diabetic kidney disease with and without albuminuria显示文摘 | Macisaac RJ Jerums G | 2011 | CurrOpinNephrolHypertens2011，20，3： | 1 |
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