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| 1 | Determinants of percutaneous coronary intervention success in repeat chronic total occlusion procedures following an initial failed attempt显示文摘AIM To investigate the rates and determinants of success of repeat percutaneous coronary intervention(PCI) following an initial failed attempt at recanalising the chronic total occlusions(CTO) percutaneously.METHODS In 445 consecutive first attempt CTO-PCI procedures in our institution,procedural failure occurred in 149(33.5%). Sixty-four re-PCI procedures were performed in 58 patients(39%) all had a single CTO. Procedural and outcome data in the re-PCI population was entered into the institutional database. A retrospective analysis of clinical,angiographic and procedural data was performed. RESULTS Procedural success was achieved in 41(64%) procedures. Univariate analysis of clinical and angiographic characteristics showed that re-PCI success was associated with intravascular ultrasound(IVUS) guidance(19.5% vs 0%,P = 0.042),while failure was associated with severecalcification(30.4% vs 9.7%,P = 0.047) and a JCTO score > 3(56.5% vs 17.1% P = 0.003). Following multiple regression analysis the degree of lesion complexity(J-CTO score > 3),IVUS use,involvement of an experienced CTO operator and LAD CTO location were significant predictors of successful re-PCI. Overall the complication rate was low,with the only MACCE two periprocedural MI's neither of which required intervention. CONCLUSION Re-PCI substantially increases the overall success rate of CTO revascularization. Predictors of re-PCI success included the use of IVUS,the involvement of an experienced CTO operator in the repeat attempt and the location of the CTO. | Cecilia Cuevas Nicola Ryan Alicia Quirós Juan Gustavo Del Angel Nieves Gonzalo Pablo Salinas Pilar Jiménez-Quevedo Luis Nombela-Franco Ivan Nunez-Gil Antonio Fernandez-Ortiz Carlos Macaya Javier Escaned | 2017 | World Journal of Cardiology2017，9，4： | 5 |
| 2 | Coronary angiography findings in cardiac arrest patients with non-diagnostic post-resuscitation electrocardiogram:A comparison of shockable and non-shockable initial rhythms显示文摘AIM To investigate the impact of coronary artery disease in a cohort of patients resuscitated from cardiac arrest with non-diagnostic electrocardiogram.METHODS From March 2004 to February 2016, 203 consecutive patients resuscitated from in or out-of-hospital sudden cardiac arrest and non-diagnostic post-resuscitation electrocardiogram(defined as ST segment elevation or pre-sumably new left bundle branch block) whounderwent invasive coronary angiogram during hospitalization were included. For purpose of analysis and comparison, patients were classified in two groups: Initial shockable rhythm(ventricular tachycardia or ventricular fibrillation; n = 148, 72.9%) and initial non-shockable rhythm(n = 55, 27.1%). Baseline characteristics, coronary angiogram findings including Syntax Score and long-term survival rates were compared. RESULTS Sudden cardiac arrest was witnessed in 95.2% of cases, 66.7% were out-of-hospital patients and 72.4% were male. There were no significant differences in baseline characteristics between groups except for higher mean age(68.1 years vs 61 years, P = 0.001) in the nonshockable rhythm group. Overall 5-year mortality of the resuscitated patients was 37.4%. Patients with non-shockable rhythms had higher mortality(60% vs 29.1%, P < 0.001) and a worst neurological status at hospital discharge based on cerebral performance category score(CPC 1-2: 32.7% vs 53.4%, P = 0.02). Although there were no significant differences in global burden of coronary artery disease defined by Syntax Score(mean Syntax Score: 10.2 vs 10.3, P = 0.96) there was a trend towards a higher incidence of acute coronary lesions in patients with shockable rhythm(29.7% vs 16.4%, P = 0.054). There was also a higher need for ad-hoc percutaneous coronary intervention in this group(21.9% vs 9.1%, P = 0.03). CONCLUSION Initial shockable group of patients had a trend towards higher incidence of acute coronary lesions and higher need of ad-hoc percutaneous intervention vs nonshockable group. | Pedro Martínez-Losas Pablo Salinas Carlos Ferrera María Teresa Nogales-Romo Francisco Noriega María Del Trigo Iván Javier Núnez-Gil Luis Nombela-Franco Nieves Gonzalo Pilar Jiménez-Quevedo Javier Escaned Antonio Fernández-Ortiz Carlos Macaya Ana Viana-Tejedor | 2017 | World Journal of Cardiology2017，9，8： | 3 |
| 3 | Fluvastatin for prevention of cardiac events following successful first percutaneous coronary inter-vention:a randomized controlledtrial显示文摘 | Serruys PW Feyter P Macaya C | 2002 | JAMA2002，287，1： | 1 |
| 4 | A randomized placebo -control trial of fluvastatin for prevention of restenoeie after successful coronary ballon angioplasty:final resuils of the fluvastatin angiographic restenosis(FLARE) trial显示文摘 | Serruys PW Foley DP Jackson G Bonnier H Macaya C Vrolix M | 1999 | Eur Heart J1999，20，： | 1 |
| 5 | Randomized evaluation of anticoagulation versus antiplatelet therapy after coronary stent implantation in high - risk patients : the multicenter aspirin and ticlopidine trial after intracoronary stenting (MATI'IS) 显示文摘 | Urban P Macaya C Rupprecht H | 1998 | Circulation1998，98，20： | 1 |
| 6 | Fluvastatin for prevention of cardiac events following successful first percutaneous intervention显示文摘 | Serruys PW de Feyter P Macaya C Kokott N Puel J Vrolix M | 2002 | JAMA2002，287，： | 1 |
| 7 | Randomized evaluation of anticoagulation in high-risk patients:The multicenter aspirin and ticlopididine trial after intracoronary stenting(MATTIS)显示文摘 | Urban P Macaya C Rupprecht HJ | 1998 | Circulation1998，98，20： | 1 |
| 8 | Fluyastatin for prevention of cardiac events following successful fisrt percutaneous coronary intervention:arandomized controlled trial显示文摘 | Serruys PW De Feyter P Macaya C | 2002 | JAMA2002，287，： | 1 |
| 9 | Impact of Chronic Kidney Disease on Platelet Function Profiles in Diabetes Mellitus Patients With Coronary Artery Disease Taking Dual Antiplatelet Therapy显示文摘 | Dominick J. Angiolillo Esther Bernardo Davide Capodanno David Vivas Manel Sabaté José Luis Ferreiro Masafumi Ueno Pilar Jimenez-Quevedo Fernando Alfonso Theodore A. Bass Carlos Macaya Antonio Fernandez-Ortiz | 2010 | Journal of the American College of Cardiology2010，，： | 1 |
| 10 | Continued benefit of coronary stenting versus balloon angioplasty: One year clinical follow-up of Benestent trial显示文摘 | Serruys P W Ruygork P | 1992 | J Am Coll Cardio1992，27，： | 1 |
| 11 | Impact of stable versus unstable coronary artery disease on 1-year outcome in elective patients undergoing multi-vessel revascularization with sirolimus-eluting stents:a sub-analysis of the ARTS Ⅱ trial显示文摘 | Valgimigli M Dawkins K Macaya C | 2007 | J Am Coll Cardiol2007，49，： | 1 |
| 12 | Fluvastatin for pre- vention of cardiac events following successful fLrst percutaneous coronary intervention: a randomized controlled trial 显示文摘 | Sermys PW de Feyter P Macaya C | 2002 | JAMA2002，287，24： | 1 |
| 13 | Early angiographic changes of side branches arising from a Palmaz-Schatz stented coronary segment: results and clinical implications显示文摘 | Iniguez A Macaya C Alfonso F | 1994 | J Am Coll Cardiol1994，23，4： | 1 |
| 14 | Fluvastafin for prevention of cardiac events following successful first percutaneous coronary intervention: a randomized controlled trial 显示文摘 | SERRUYS PW DE FEYTER P MACAYA C | 2002 | JAMA2002，287，24： | 1 |
| 15 | Painful ophthalmoplegia with reversible carotid stenosis in a child 显示文摘 | Toro M Macaya A Vazquez E | 2001 | Pediatr Neurol2001，24，4： | 1 |
| 16 | Fluvastatin for prevention of cardiac events following successful first percutaneous coronary intervention:a randomized controlled trial显示文摘 | Serruys PW De Feyter P Macaya C | 2002 | JAMA2002，287，： | 1 |
| 17 | Muhivessel coronary revas- cularlzation in patients with and without diabetes mellitus: 3-year follow-up of the ARTS-Ⅱ ( Arterial Revascularization Therapies Study-Part Ⅱ) trlal显示文摘 | Daemen J Kuck KH Macaya C | 2008 | JAm Coil Cardiol2008，52，24： | 1 |
| 18 | Response to letter regarding article, 'effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) trial'显示文摘 | IBANEZ B MACAYA C S? NCHEZ-BRUNETE V | 2014 | Circulation2014，130，3： | 1 |
| 19 | Apoptosis in substantia nigra following developmental striatal excitotoxic injury显示文摘 | Munell F | 1994 | Proc Natl Acad Sci USA1994，91，： | 1 |
| 20 | Fluvastatin for prevention of cardiac events following successful first percutaneous coronary intervention: a randomized controlled trial 显示文摘 | Feyter P Macaya C | 2002 | JAMA2002，287，31： | 1 |
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