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1PAHs in the Fraser River basin: a critical appraisal of PAH ratios as indicators of PAH source and composition显示文摘Mark B Yunker Robie W Macdonald Roxanne Vingarzan Reginald H Mitchell Darcy Goyette Stephanie Sylvestre 2002Organic Geochemistry2002,,4:5
2健康领域的文化能力显示文摘1背景 尽管人类对其他社会的兴趣纵贯历史的各个阶段,但是检验不同文化概念对人类健康实践的影响从20世纪才开始,当时是伴随着长期的人类学田野调查产生的,这些田野调查揭露了不同文化之间相关卫生实践的多样性、复杂性和连续性。Napier A D Ancarno C Butler B Calabrese j Chater A Chatterjee H Guesnet F Home R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams AC Willott C Wilson J Woolf K 2016中国卫生政策研究2016,9,2:5
3Comparison of cytokine and phosphoprotein profiles in idiopathic and Crohn’s disease-related perianal fistula显示文摘BACKGROUND Perianal fistulae are either primary(idiopathic)or secondary[commonly associated with Crohn’s disease,(CD)].It is assumed,although not proven,that the pathophysiology differs.AIM To systematically compare the clinical phenotypes,cytokine and phosphoprotein profiles of idiopathic and CD-related perianal fistulae.METHODS Sixty-one patients undergoing surgery for perianal fistula were prospectively recruited(48 idiopathic,13 CD)into a cohort study.Clinical data,including the Perineal Disease Activity Index(PDAI)and EQ-5D-5L were collected.Biopsies of the fistula tract,granulation tissue,internal opening mucosa and rectal mucosa were obtained at surgery.Concentrations of 30 cytokines and 39 phosphoproteins were measured in each biopsy using a magnetic bead multiplexing instrument and a chemiluminescent antibody array respectively.Over 12000 clinical and 23500 laboratory measurements were made.RESULTS The PDAI was significantly higher(indicating more active disease)in the CD group with a mean difference of 2.40(95%CI:0.52-4.28,P=0.01).Complex pathoanatomy was more prevalent in the CD group,namely more multiple fistulae,supralevator extensions,collections and rectal thickening.The IL-12p70 concentration at the internal opening specimen site was significantly higher(median difference 19.7 pg/mL,99%CI:0.2-40.4,P=0.008)and the IL-1RA/IL-1βratio was significantly lower in the CD group at the internal opening specimen site(median difference 15.0,99%CI=0.4-50.5,P=0.008).However in the remaining 27 cytokines and all 39 of the phosphoproteins across the four biopsy sites,no significant differences were found between the groups.CONCLUSION CD-related perianal fistulae are more clinically severe and anatomically complex than idiopathic perianal fistulae.However,overall there are no major differences in cytokine and phosphoprotein profiles.James B Haddow Omar Musbahi Thomas T MacDonald Charles H Knowles 2019World Journal of Gastrointestinal Pathophysiology2019,10,4:2
4文化、不平等性与卫生服务提供显示文摘1动态不平等性对基层医疗卫生人力的影响 政治、社会、文化、专业群体皆建立在一致且常规的人类行为之上。当遭受巨大变革和内外压力时,这些群体会变得十分脆弱。尤其在动荡时期,这些群体往往更关注社会和文化的差异性,而非二者的一致性。尽管社会中的个体思维和行为会呈现较大的差异,但对健康的感知具有统一性,并在更广范围人群内尤为突出,这主要归因于文化价值观的作用。广义的文化心态会随着时间和地理位置的不同而不同,就像健康的社会决定因素也会因文化类型的不同而产生差异。Napier A D Ancarno C Butler B Calabrese J Chater A Chatterjee H Guesnet F Horne R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams A C Willott C Wilson J Woolf K 2016中国卫生政策研究2016,9,3:2
5Colloidal Au and Au-alloy catalysts for direct borohydride fuelcells: Electrocatalysis and fuel cell performance 显示文摘ATWAN M H MACDONALD C L B NORTHWOOD D O 2006J Power Sources2006,158,1:1
6Role of the vitamin D receptor in hair follicle biology显示文摘DEMAY M B MACDONALD P N SKORIJA K 2007J Steroid Biochem Mol Biol2007,103,35:1
7PAHs in the Fraser River Basin : a critical appraisal of PAH ratios as indicators of PAH source and composition 显示文摘Yunker M B Macdonald R W Vingarzan R 2002Organic Geochemistry2002,33,4:1
8PAHs in the fraser fiver basin:a critical appraisal of PAH ratios as indicators of PAH source and composition显示文摘Yunker M B Macdonald R W Vingarzan R 2002Organic Geochemistry2002,33,4:1
9Polycyclic aromatic hydrocarbon composition and potential sources for sediment samples from the Beaufort and Barents Seas 显示文摘Yunker M B Snowdon L R Macdonald R W 1996Environmental Science and Technology1996,30,4:1
10Interleukin - 6 release from human skeletal muscle during exercise : relation to AMPK activity显示文摘MacDonald C Wojtassewski JF Pedersen BK Kiens B Richter EA 2003J Appl Physio120032003,,:1
11医疗卫生保健文化的反思及促进健康与文化融合的建议显示文摘1医疗卫生保健文化的反思1.1健康文化与医学知识如果医务人员有充足的时间对患者进行诊断并帮助患者进行社区护理,就可在节省卫生费用的同时改善健康结果。整合型社区护理能缩小不同文化背景和群体健康需求的差异。然而,全球范围内对整合型社区护理的投入较少,原因之一就是20世纪对临床服务的重视弱化了卫生服务提供过程中的同情心理。当然,患者也对医学知识存在显性和隐性的影响(特别是当其因不遵医嘱而受到指责时)。Napier A D Ancarno C Butler B Calabrese J Chater A Chatterjee H Guesnet F Horne R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams A C Willott C Wilson JWoolf K 2016中国卫生政策研究2016,9,4:1
12Trifluoroacetate profiles in the Arctic,Atlantic,and Pacific Oceans显示文摘B F Scott R W Macdonald 0,,:1
13Picloram and aminopyalid sorption to soil and clay minerals显示文摘FAST B J FERRELL J A MACDONALD G E 0,,:1
14The corrosion of carbon steel by wet elemental sulphur显示文摘MACDONALD D D ROBERTS B E HYNE J B 1978Corrosion Science1978,18,5:1
15Mechanic electrical and thermal characterization of G-10CR and G-11CR glass-cloth/epoxy laminates between room temperature and 4K显示文摘Kasen M B MacDonald G R Beekman DH Jr Schramm 1986Cryogenics1986,26,:1
16PAHs in the Fraser river basin:a critical appraisal of PAH ratios as indicators of PAH sources and composition 显示文摘Yunker M B Macdonald R W Vingarzan R 2002Organic Geochemistry2002,33,4:1
17Febrile convulsions in 220 Children-neurological sequelae at 12 years follow-up 显示文摘MacDonald B K Johnson A L Sandera J W 1999Euro Neurol1999,41,4:1
18Integrating stereolithography and direct print technologies for 3D structural electronics fabrication 显示文摘Lopes A J MacDonald E Wicker R B 2012Rapid Prototyping Journal2012,18,2:1
19Development of a novel method of tube bending using finite element simulation显示文摘Baudin S Ray P MacDonald B J 2004Journal of Materials Processing Technology2004,,:1
20Enhanced Production of Surfactin from Bacillus Subtilisby Continuous Product Removal and Metal Cation Additions显示文摘Cooper D G Macdonald C R Duff S B J 1981Appl Environ Microbiol1981,42,3:1
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