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| 1 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 2 | How often are angiotentensin Ⅱ and aldosterrone concentrations raised during chronic ACEinhibitortreatment in cardiacfailure显示文摘 | MAC FADYEN R J LEE A F MORTON J J | 1999 | Heart1999，82，1： | 2 |
| 3 | Anaerobic digestion of organic solid wastes. An overview of research achievements and perspectives显示文摘 | J Mata-Alvarez S Macé P Llabrés | 2000 | Bioresource Technology2000，，1： | 2 |
| 4 | Plasma glucagon and insulin responses depend on the rate of appearance of amino acids after ingestion of different protein solutions in humans显示文摘 | Calbet J A L Mac Lean D A | 2002 | J Nutr2002，132，： | 1 |
| 5 | Preparation, X ray structure and properties of a hexabrominated, symmet ric indole trimer and its TCNQ adduet: a new route to func tional molecular systems显示文摘 | Robertson N Parsons S Mac Lean E J | 2000 | J Mat Chem2000，10，9： | 1 |
| 6 | 2D and 3D finite element a- nal ysis of a three stage forging sequence 显示文摘 | Mac Cormack C Monaghan J | 2002 | Journal of Ma- teri-als Processing Technology2002，，127： | 1 |
| 7 | De- termination of undegradable intake protein digestibility of forages using the mobile nylon bag technique 显示文摘 | HAUGEN H L IVAN S K MAC DONALD J C | 2006 | J Anita Sci2006，84，： | 1 |
| 8 | Embolus loetion affects the sensitivity of a rapid quantitative D-dimer assay in the diagnosis of pulmonary embolism显示文摘 | De Monye W Sanson B J Mac Ciilavry MR | 2002 | Am J Pespir Crit Care Med2002，165，3： | 1 |
| 9 | Thermal degradation of glu- cosinolates 显示文摘 | Mac Leod A J Panesar S S Gil V | 1981 | Phytochemistry1981，20，5： | 1 |
| 10 | Anaerobic digestion of organicsolid wastes:Anoverview of research achievements and perspectives显示文摘 | Alvarez J M Macés L P | | 0，，74： | 1 |
| 11 | Analysis of effects of 13 types of phenol compounds in aloe lotion显示文摘 | Park ink Park H J Aayoung Mac | 1999 | Analysis of Plant Extracts1999，8，： | 1 |
| 12 | Early mortality after radical radiotherapy for non-small-cell lung cancer: comparison of PET-staged and conventionally staged cohorts treated at a large tertiary referral center 显示文摘 | Mac Manus MP Wong K Hicks R J | 2002 | Int J Radiat Oncol Biol Phys2002，52，2： | 1 |
| 13 | Comparison of prevalence of depression in mothers of twins and mothers of singletons 显示文摘 | Thorpe K Golding J Mac Gillivray I Greenwood R | 1991 | BMJ1991，13，： | 1 |
| 14 | Molecular analysis of 30 Niemann-Pick type C patients from Spain显示文摘 | Macías-Vidal J Rodríguez-Pascau L Sánchez-Ollé G | 2011 | Clin Genet2011，80，1： | 1 |
| 15 | Hydrogenolysis of glycerol to 1, 2-propanediol on the high dispersed SBA-15 supported copper catalyst prepared by the ion- exchange method 显示文摘 | ZHENG J ZHU W C MAC X | 2010 | Reaction Kinetics Mechanisms and Catalysis2010，99，2： | 1 |
| 16 | A comparison be tween the high temperature electrode/electrolyte reactions of LixCoO2 and LixMn2O4显示文摘 | Hatchaid T D Dahn J R | 2001 | J Electrochem Soc2001，148，7： | 1 |
| 17 | Myc-Max heterodimers acti- vate a DEAD box gene and interact with multiple E box-related sites in vivo显示文摘 | Grandori C Mac J Siebelt F | 1996 | EMBO J1996，15，16： | 1 |
| 18 | Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase inhibition 显示文摘 | Mac Keigan J P Taxman D J Hunter D | 2002 | Clin Cancer Res2002，8，7： | 1 |
| 19 | Recycling of waste printed circuit boards by microwave-induced pyrolysis and featured mechanical processing显示文摘 | SUN J WANG W LIU Z MAC | | 0，，20： | 1 |
| 20 | The prevention of progression of arterial disease and diabetes (POPADAD) trial:factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease显示文摘 | Belch J Mac Cuish A Campbell I | | 0，，： | 1 |
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