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| 1 | Genotoxicity of ferric oxide nanoparticles in Raphanus sativus:Deciphering the role of signaling factors,oxidative stress and cell death显示文摘We have studied the genotoxic and apoptotic potential of ferric oxide nanoparticles(Fe_2O_3-NPs) in Raphanus sativus(radish).Fe_2O_3-NPs retarded the root length and seed germination in radish.Ultrathin sections of treated roots showed subcellular localization of Fe_2O_3-NPs,along with the appearance of damaged mitochondria and excessive vacuolization.Flow cytometric analysis of Fe_2O_3-NPs(1.0 mg/m L) treated groups exhibited 219.5%,161%,120.4% and 161.4% increase in intracellular reactive oxygen species(ROS),mitochondrial membrane potential(ΔΨm),nitric oxide(NO) and Ca2+influx in radish protoplasts.A concentration dependent increase in the antioxidative enzymes glutathione(GSH),catalase(CAT),superoxide dismutase(SOD) and lipid peroxidation(LPO) has been recorded.Comet assay showed a concentration dependent increase in deoxyribonucleic acid(DNA) strand breaks in Fe_2O_3-NPs treated groups.Cell cycle analysis revealed 88.4% of cells in sub-G1 apoptotic phase,suggesting cell death in Fe_2O_3-NPs(2.0 mg/m L) treated group.Taking together,the genotoxicity induced by Fe_2O_3-NPs highlights the importance of environmental risk associated with improper disposal of nanoparticles(NPs) and radish can serve as a good indicator for measuring the phytotoxicity of NPs grown in NP-polluted environment. | Quaiser Saquib Mohammad Faisal Abdulrahman A.Alatar Abdulaziz A.Al-Khedhairy Mukhtar Ahmed Sabiha M.Ansari Hend A.Alwathnani Mohammad K.Okla Sourabh Dwivedi Javed Musarrat Shelly Praveen Shams T.Khan Rizwan Wahab Maqsood A.Siddiqui Javed Ahmad | 2016 | Journal of Environmental Sciences2016，28，9： | 2 |
| 2 | Significance of Bacillus subtilis strain SJ-101 as a bioinoculant for concurrent plant growth promotion and nickel accumulation in Brassica juncea显示文摘 | Sabina Zaidi Saima Usmani Braj Raj Singh Javed Musarrat | 2006 | Chemosphere2006，，6： | 2 |
| 3 | Isolation and Characterization of Phorate Degrading Soil Bacteria of Environmental and Agronomic Significance显示文摘 | BANO N MUSARRAT J | 2003 | Letters in Applied Microbiology2003，36，： | 1 |
| 4 | Color Doppler Misoprostol Response Study(CDMRS):An Evaluation Tool for Patients Awaiting Myomectomy显示文摘 | Musarrat Hasan Ayesha Nasir Erum Saba | 2014 | Journal of Medical Ultrasound2014，62，22： | 1 |
| 5 | Chemical speciation of respirable suspended particulate matter during a major firework festival in India显示文摘 | Sayantan Sarkar Pandit S. Khillare Darpa S. Jyethi Amreen Hasan Musarrat Parween | 2010 | Journal of Hazardous Materials2010，，1： | 1 |
| 6 | Localization of O6-alkylguanine transferase in cancer susceptible cells of human female breast显示文摘 | Musarrat J Wilson JA Wani AA | 1996 | Cancer Lett1996，108，1： | 1 |
| 7 | Cytotoxic and necrotic responses in human amniotic epithelial (WISH) ceils exposed to or- ganophosphate insecticide phorate显示文摘 | Saquib Q Musarrat J Siddiqui M A | 2012 | Mutation Research/Genetic Toxicology and Environmental Mutagenesis2012，744，2： | 1 |
| 8 | Localization of O^6 alkylguanine transferase in cancer susceptible cells of human female breast显示文摘 | Musarrat J Wilson JA Wani AA | 1996 | Cancer Lett1996，108，1： | 1 |
| 9 | Characterization of a newPseudomonas aeruginosastrain NJ-15as a potential biocontrol agent显示文摘 | BANO N MUSARRAT J | 2003 | Current Microbiology2003，46，5： | 1 |
| 10 | A detailed analysis of the pyrolysis products from dioctyltin maleate and its mixture with PVC显示文摘 | Ian C McNeill Musarrat H Mohammed Cole W J | 1998 | Polymer Degradation and Stability1998，61，： | 1 |
| 11 | Tetracycline-Cu(II) photo-induced fragmentation of serum albumin显示文摘 | Mateen A Khan Javed Musarrat | 2002 | Comparative Biochemistry and Physiology Part C2002，131，： | 1 |
| 12 | Prognostic and aetiological relevance of 8-hydroxyguanosine in human breast carcinogenesis显示文摘 | MUSARRAT J AREZINA-WILSON J WANI A A | 1996 | Eur J Cancer A1996，32，7： | 1 |
| 13 | Prognostic and aetiological relevance of 8 - hydroxyguanosine in human breast carcinogenesis 显示文摘 | Musarrat J Arezina - Wilson J Wani AA | 1996 | Eur J Cancer1996，32，： | 1 |
| 14 | O(6)-alkylguanine DNA alkyltransferase activity levels in normal, benign and malignant human female breast显示文摘 | Musarrat J Wilson JA Abou-Issa H | 1995 | Biochem Biophys Res Commun1995，208，2： | 1 |
| 15 | Can demography predict academic dishonest behaviors of students? a case of Pakistan 显示文摘 | Mian Sajid Nazir Muhammad Shakeel Aslam Muhammad Musarrat Nawaz | 2011 | International Education Studies2011，4，2： | 1 |
| 16 | Prognostic and aetiological relevance of 8-hydroxyguanosine in human breast carcinogenesis显示文摘 | MUSARRAT J AREINA-WILSON J WANI A A | 1996 | Eur J Cancer1996，32，7： | 1 |
| 17 | Bioreactor studies on the endophytic fungusEntrophospora infrequens for the production of an anticancer alkaloid camptothecin 显示文摘 | Amna T Puri SC Verma V Sharma JP Khajuria RK Musarrat J Spiteller M Qazi GN | 2006 | Can J Microbiol2006，52，3： | 1 |
| 18 | Characterization of a new Pseudomonas aeruginosa strain NJ-I5 as a potential biocontrol agent显示文摘 | Bano N Musarrat J | 2003 | Current Microbiology2003，46，5： | 1 |
| 19 | Metformin,B12 and homocysteine levels:the plausible cause or effect? 显示文摘 | Musarrat K Kalathil D Varughese GI | 2008 | Formos Med Assoc2008，107，6： | 1 |
| 20 | Differential binding of tetracycline with serum basic principles with visual demonstrations 显示文摘 | KHAN M A MUZAMMIL S MUSARRAT J | 2001 | Biochemistry And Molecular Biology2001，29，1： | 1 |
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