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	题名	作者	年代	出处	被引量
1	An antioxidant resveratrol significantly enhanced replication of hepatitis C virus显示文摘AIM:To elucidate the effect of antioxidants,resveratrol (RVT)and astaxanthin(AXN),on hepatitis C virus(HCV) replication. METHODS:We investigated the effect of recent popular antioxidant supplements on replication of the HCV replicon system OR6.RVT is a strong antioxidant and a kind of polyphenol that inhibits replication of various viruses.AXN is also a strong antioxidant.The replication of HCV RNA was assessed by the luciferase reporter assay.An additive effect of antioxidants on antiviral effects of interferon(IFN)and ribavirin(RBV) was investigated.RESULTS:This is the first report to investigate the effect of RVT and AXN on HCV replication.In contrast to other reported viruses,RVT significantly enhanced HCV RNA replication.Vitamin E also enhanced HCV RNA replication as reported previously,although AXN didnot affect replication.IFN and RBV significantly reduced HCV RNA replication,but these effects were dose-dependently hampered and attenuated by the addition of RVT.AXN didnot affect antiviral effects of IFN or RBV. CONCLUSION:These results suggested that RVT is not suitable as an antioxidant therapy for chronic hepatitis C.	Mitsuyasu Nakamura Masanori Ikeda Ryota Hokari Nobuyuki Kato Toshifumi Hibi Soichiro Miura	2010	World Journal of Gastroenterology2010，16，2：	3
2	A new stereoscopic endoscopy system: Accurate 3-dimensional measurement in vitro and in vivo with distortion-correction function显示文摘	Kenshi Yao Toshiyuki Matsui Hisashi Furukawa Tsuneyoshi Yao Toshihiro Sakurai Tomoko Mitsuyasu	2002	Gastrointestinal Endoscopy2002，，3：	2
3	The virologic, immunologic, and chnical effects of interleukin 2 with potent antiretroviral therapy in patients with moderately advanced human immunodeficiency virus infection: a randomized controlled clinical trial-AIDS Clinical Trials Group 328显示文摘	Mitsuyasu R Gelman R Chemg DW	2007	Arch Intern Med2007，167，6：	1
4	Telomerase activity in oral and maxillofacial tumors显示文摘	Liao J Mitsuyasu T Yamane K	2000	Oral Oncol2000，36，4：	1
5	Clinical gene therapy research utilizing ribozymes:application to the treatment of HIV/AIDS显示文摘	Ngok FK Mitsuyasu RT Macpherson JL	2004	Methods Mol Biol2004，252，：	1
6	Morphology of vulnerable coronary plaque: Insights from follow- up of patients examined by intravascular ultrasound before an acute coronary syndromes显示文摘	MASAKAZU Y MITSUYASU T KOJIRO A	2000	Am J Coll Cardiol2000，35，：	1
7	Endoscopic removal of a dentalimplant displaced into the maxillary sinus:technical note显示文摘	Nakamura N Mitsuyasu T Ohishi M	2004	Int J O-ral Maxillofac Surg2004，33，2：	1
8	Epithelial stem cells in teeth显示文摘	Harada H Mitsuyasu T Toyono T	2002	Odontology2002，90，：	1
9	Positive results with autologous transplant of ZFN-modified CD4 T-cells:a step toward a practical,functional cure for HIV显示文摘	Jay Lalezari R Mitsuyasu S Deeks	2011	AIDS Patient Care STDS2011，25，11：	1
10	Marsupialization for odontogenic keratocyst: long-term follow-up analysis of the effects and changes in growth characteristics显示文摘	Nakamura N Mitsuyasu T Mitsuyasu Y	2002	Oral Surg Oral Med Oral Pathol Oral Radial Endod2002，94，5：	1
11	Marsupial?ization for odontogenic keratocysts , Long+- term follow r- up analysis of the effects and changes in growth characteristics显示文摘	Nakamura N Mitsuyasu T Mitsuyasu y	2002	Oral Surg Oral Med Oral Pathol Oral Radiol Endod2002，94，54：	1
12	Cancer biomarkers in HIV patients显示文摘	Richard F Ambinder Kishor Bhatia Otoniel Martinez-Maza Ronald Mitsuyasu	2010	Current Opinion in HIV and AIDS2010，，6：	1
13	Telomerase activity in oral and maxillofacial tumors显示文摘	Liao J Mitsuyasu T Yamane K	2000	Oral Oncol2000，36，4：	1
14	Observations of the direc-tional spectrum of ocean wave using a cloverleaf buoy显示文摘	MITSUYASU H TASAI F SUHARA T		0，，04：	1
15	Marsupialization for odontogenic keratocysts:Long-term follow-up analysis of the effects and changes in growth characteristics 显示文摘	Mitsuyasu T Mitsuyasu Y	2002	Oral Surg Oral Med Oral Pathol Oral Radiol Endod2002，94，5：	1
16	Marsupialization for odontogenic keratocysts:long-term follow-up analysis of the effects and changes in growth characteristics显示文摘	Nakamura N Mitsuyasu T Mitsuyasu Y	2002	Oral Surg Oral Med Oral Pathol Oral Radiol Endod2002，94，5：	1
17	Cutting edge:dominnant effect of Ile50Val variant of the human IL-4 receptor α-chain in IgE synthesis显示文摘	Mitsuyasu H Yanagihara Y Mao XQ Gao PS Arinobu Y Ihara K	1996	J Immunol1996，162，3：	1
18	Observation of the directional wave spectra of ocean waves using a cloverleaf buoy显示文摘	Mitsuyasu H	1975	J of Physical Ocea- nography1975，，5：	1
19	Overexpression of bel- 2 protein inhibits terminal differentiation of oral keratinocytes in vitro 显示文摘	Harada H Mitsuyasu T Seta Y	1998	J Oral Pathol Med1998，27，1：	1
20	Comparison of long-term results between different approaches to ameloblastoma显示文摘	Nakamura N Higuchi Y Mitsuyasu T		0，，01：	1

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