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| 1 | Prognostic value of increased carbohydrate antigen in patients with heart failure显示文摘AIM:To study the prognostic value of carbohydrateantigen 125(CA125) and whether it adds prognostic information to N-terminal pro-brain natriuretic peptide(NT-proBNP) in stable heart failure(HF) patients.METHODS:The predictive value of CA125 was retrospectively assessed in 156 patients with stable HF remitted to the outpatient HF unit for monitoring from 2009 to 2011.Patients were included in the study if they had a previous documented episode of HF and received HF treatment.CA125 and NT-proBNP concentrations were measured.The independent association between NT-proBNP or CA125 and mortality was assessed with Cox regression analysis,and their combined predictive ability was tested by the integrated discrimination improvement(IDI) index.RESULTS:The mean age of the 156 patients was 72 ± 12 years.During follow-up(17 ± 8 mo),27 patients died,1 received an urgent heart transplantation and 106 required hospitalization for HF.Higher CA125 values were correlated with outcomes:58 ± 85 KU/L if hospitalized vs 34 ± 61 KU/L if not(P < 0.05),and 94 ± 121 KU/L in those who died or needed urgent heart transplantation vs 45 ± 78 KU/L in survivors(P < 0.01).After adjusting for propensity scores,the highest risk was observed when both biomarkers were elevated vs not elevated(HR = 8.95,95%CI:3.11-25.73; P < 0.001) and intermediate when only NT-proBNP was elevated vs not elevated(HR = 4.15,95%CI:1.41-12.24; P < 0.01).Moreover,when CA125 was added to the clinical model with NT-proBNP,a 4%(P < 0.05) improvement in the IDI was found.CONCLUSION:CA125 > 60 KU/L identified patients in stable HF with poor survival.Circulating CA125 level adds prognostic value to NT-proBNP level in predicting HF outcomes. | Ana B Méndez Jordi Ordonez-Llanos Andreu Ferrero Mariana Noguero Teresa Mir Josefina Mora Antoni Bayes-Genis Sònia Mirabet Juan Cinca Eulàlia Roig | 2014 | World Journal of Cardiology2014，6，4： | 13 |
| 2 | Antibacterial efficacy of the seed extracts of Melia azedarach against some hospital isolated human pathogenic bacterial strains显示文摘Objective:To investigate the antibacterial potential of the polar and non-polar extracts of the seeds of Melia azedarach(M.azedarach) L.(Meliaceae) against eighteen hospital isolated human pathogenic bacterial strains.Methods:Petrol,benzene,ethyl acetate,methanol,and aqueous extracts at five different concentrations(1,2,5,10 and 15 mg/mL) were evaluated.Disk diffusion method was followed to evaluate the antibacterial efficacy.Results:All extracts of the seeds demonstrated significant antibacterial activity against tested pathogens.Among all extracts,ethyl acetate extract revealed the highest inhibition comparatively.The present study also favored the traditional uses reported earlier.Conclusions:Results of this study strongly confirm that the seed extracts of M.azedarach could be effective antibiotics,both in controlling gram-positive and gram-negative human pathogenic infections. | Abdul Viqar Khan Qamar Uddin Ahmed M Ramzan Mir Indu Shukla Athar Ali Khan | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，6： | 11 |
| 3 | Ly49 receptors activate angiogenic mouse DBA+ uterine natural killer cells显示文摘 | Patricia DA Lima Megan M Tu Mir Munir A Rahim Annie R Peng B Anne Croy Andrew P Makrigiannis | 2014 | Cellular & Molecular Immunology2014，11，5： | 3 |
| 4 | Microstructural, structural and electrical properties of La 3+ -modified Bi 4 Ti 3 O 12 ferroelectric ceramics显示文摘 | V.B. Santos J.-C. M’Peko M. Mir V.R. Mastelaro A.C. Hernandes | 2008 | Journal of the European Ceramic Society2008，，4： | 2 |
| 5 | Determining the influence of structure on hybridization using oligonucleotide arrays显示文摘 | MIR K U SOUTHERN E M | 1999 | Nat Biotechnol1999，17，8： | 1 |
| 6 | Effect of dietary supplementation with either conjugated linoleic acid(CLA)or linoleic acid rich oil on the CLA content of lamb tissues显示文摘 | Mir Z Rushfeldt M L Mir P S | 2000 | Small Rum Res2000，36，： | 1 |
| 7 | Issues in reducing the cogging torque of mass-produced permanent-magnet brushless DC motor显示文摘 | Islam M S Mir S Sebastian T | 2004 | IEEE Transactions on Industry Applications2004，40，3： | 1 |
| 8 | PI and fuzzy estimators for tuning the stator resistance in direct torque control of induction machines显示文摘 | Elbuluk M E Zinger D S | 1998 | IEEE Trans on Power Electronics1998，13，2： | 1 |
| 9 | Assessment of the aroma profiles of low–alcohol beers using HS–SPME–GC–MS显示文摘 | Riu–Aumatell M MiróP Serra–Cayuela A | 2014 | Food Research International2014，57，19： | 1 |
| 10 | Tissue ablation with irreversible eleetroporation显示文摘 | Davalos R V Mir L M Rubinsky B | 2005 | Annals of Biomedical Engineering2005，33，2： | 1 |
| 11 | Texture analysis of CT images显示文摘 | Mir A H Hanmandlu M Tandon S N | 1995 | Engineering in Medicine and Biology Magazine1995，14，6： | 1 |
| 12 | On-farm monitoring of soil nitrate-nitrogen in irriga- ted cornfields in the Ebro Valley (Northeast Spain)显示文摘 | VILLAR MIR J M VILLAR-MIR P STOCKLE C O | 2002 | Agronomy Journal2002，18，： | 1 |
| 13 | Down-regulation ofmiR-101 in endothelial cells promotes blood vessel formation through reduced repression of EZH2显示文摘 | Smits M Mir SE Nilsson RJ | 2011 | PLoS One2011，6，16： | 1 |
| 14 | A game theory approach in sellerbuyer supply chain 显示文摘 | M Esmaeili Mir - Bahador Aryanezhad P Zeephongsekul | 2009 | European Journal of Operation Research2009，，195： | 1 |
| 15 | Anti-fouling characteristics of surface-confined oligonucleotide strands bioconjugated on streptavidin platforms in the presence of nanomateriais显示文摘 | Mir M Cameron PJ Zhong X | 2009 | Talanta2009，78，3： | 1 |
| 16 | Management of unstable thoracolumbar spinal injuries by posterior short segment spinal fixation显示文摘 | Butt MF Farooq M Mir B | 2007 | Int Orthop2007，31，2： | 1 |
| 17 | Evaluation of certain new insecticides against Lepidopteran pests of cabbage显示文摘 | Sreekanth M Babu T Ramesh Sultan Mir Azam | 2000 | International Pest Control2000，42，4： | 1 |
| 18 | Molecular interactions on microarrays显示文摘 | Southern E Mir K Shchepinov M | 1999 | Nature Genet1999，21，1： | 1 |
| 19 | {i25 suppresses in?vasion and metastasis of gastric cancer by targeting ILK 显示文摘 | Wang M Li C Nie H Down-regulated miR | 2012 | FEBS Lett2012，586，16： | 1 |
| 20 | Management of unstablethoracolum-bar spinal injuries by posterior short segmentspinal fixation显示文摘 | Butt MF Farooq M Mir B | 2007 | Int Orthop2007，31，2： | 1 |
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