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| 1 | 头颈癌化疗的Meta分析——93组17346例患者随机实验最新资料显示文摘Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 93 randomised trials and 17,346 patients. Pignon JP, Maitre AL, Maillard E, et al. Radiother Oncol, 2009 May 14. | Pignon JP Matre AL Maillard E | 2009 | 中国口腔颌面外科杂志2009，7，4： | 79 |
| 2 | Reconstruction of chemically burned rat corneal surface by bone marrow-derived human mesenchymal stem cells显示文摘 | Ma Y Xu Y Xiao Z Yang W Zhang C Song E Du Y Li L | 2006 | 中国生物学文摘2006，20，5： | 58 |
| 3 | Lower Bifidobacteria counts in both duodenal mucosa-associated and fecal microbiota in irritable bowel syndrome patients显示文摘AIM: To determine the composition of both fecal and duodenal mucosa-associated microbiota in irritable bowel syndrome (IBS) patients and healthy subjects using molecular-based techniques. METHODS: Fecal and duodenal mucosa brush samples were obtained from 41 IBS patients and 26 healthy subjects. Fecal samples were analyzed for the composition of the total microbiota using fluorescent in situ hybridization (FISH) and both fecal and duodenal brush samples were analyzed for the composition of bif idobacteria using real-time polymerase chain reaction. RESULTS: The FISH analysis of fecal samples revealed a 2-fold decrease in the level of bifidobacteria (4.2 ± 1.3 vs 8.3 ± 1.9, P < 0.01) in IBS patients compared to healthy subjects, whereas no major differences in other bacterial groups were observed. At the species level, Bifidobacterium catenulatum levels were significantly lower (6 ± 0.6 vs 19 ± 2.5, P < 0.001) in the IBS patients in both fecal and duodenal brush samples than in healthy subjects.CONCLUSION: Decreased bifidobacteria levels in both fecal and duodenal brush samples of IBS patients compared to healthy subjects indicate a role for microbiotic composition in IBS pathophysiology. | Angèle PM Kerckhoffs Melvin Samsom Michel E van der Rest Joris de Vogel Jan Knol Kaouther Ben-Amor Louis MA Akkermans | 2009 | World Journal of Gastroenterology2009，15，23： | 33 |
| 4 | 下肢浅静脉治疗术后的加压疗法:美国静脉论坛血管、外科学会、美国静脉学会、血管医学学会和国际静脉联盟的临床实践指南显示文摘一、指南的由来下肢浅静脉治疗术后应用压力治疗的方式是几代血管外科医师多年临床经验积累所得,现主要应用于大隐静脉剥脱术、下肢静脉点状剥脱术及静脉硬化治疗等。目前单就静脉硬化治疗而言,术后压力治疗的推荐也是基于相关文献及实验验证[1],但对于其他术式,尤其是对于大隐静脉的热消融术,目前还没有形成规范统一的建议,这也使得当前的压力治疗具有很大的临床差异性。 | Lurie F Lal BK Antignani PL Blebea J Bush R Caprini J Davies A Forrestal M Jacobowitz G Kalodiki E Killewich L Lohr J Ma H Mosti G Partsch H Rooke T Wakefield T 李丹(译) 陈程浩(译) 牛传强(译) 张靖(译) 黄建忠(译) | 2020 | 中华介入放射学电子杂志2020，8，4： | 16 |
| 5 | 感染性休克病人的血流动力学特点及意义显示文摘目的 了解感染性休克病人早期血流动力学改变的特点及与预后关系。方法 临床前瞻性研究 ,监测感染性休克早期血流动力学改变并分析与预后的关系。结果 共连续观察 4 8例病人 ,其中 2 5例(5 2 % )死亡。一些指标的水平在死亡者与生存者间差别较大 ,其中包括平均肺动脉压 (MPAP)、肺动脉楔压 (PAWP)、体 /肺循环阻力指数 (SVRI/PVRI)、左 /右心做功 (LCW/RCW )和左 /右心每搏动 (LCSW/RCSW)等血流动力学指标和氧合指数、动脉混合静脉血含氧量差 (a vDO2 )、全身性炎症反应综合征(SIRS)指标积分等。结论 感染性休克病情凶险 。 | 赵擎宇 贾清颜 Weigand MA Martin E Bardenheuer HJ | 2002 | 中华急诊医学杂志2002，11，3： | 16 |
| 6 | Quantitative Trait Loci Mapping of Maize Yield and Its Components Under Different Water Treatments at Flowering Time显示文摘干旱或水应力是导致玉米(Zea mays L.) 的一个严重农学的问题在全世界的收益损失。与干旱忍耐引起混血儿是为解决这个问题的一条重要途径。然而,更低的效率和引起混血儿的一个更长的时期是传统的繁殖节目的劣势。到传统的繁殖节目的适用的分子的标记技术能改进繁殖干旱容忍的玉米的效率,这通常被认出。在玉米干旱忍耐的研究为使用提供有用信息,为产量和它的部件印射并且标注量的特点 loci (QTL ) 根据一个混合线性模型的原则在现在的学习被执行。221 recombinant Yuyu 22 的生来的线(RIL ) 在浇得好、强调水的条件下面被种。在以前的处理组,植物很好被灌溉,而那些在 flowering 时间在后者处理组被强调。每遗传型的十植物连续不断地被种那是 3.00 m ??? 隤? ???? ? 跧?? 闦?? ? 郦 ?? ? 釧 ? ? 跧? 釧??? 雧???????? 雧? 吗?? | Gui-He Lu Ji-Hua Tang Jian-Bing Yan Xi-Qing Ma Jian-Sheng Li Shao-Jiang Chen Jian-Cang Ma Zhan-Xian Liu Li-Zhu E Yi-Rong Zhang Jing-Rui Dai | 2006 | Journal of Integrative Plant Biology2006，48，10： | 13 |
| 7 | 6min步行试验中不同指令对行走距离的影响显示文摘6min步行试验(6-minwalktest,6MWT)作为测定心肺功能的一种方法,一直以使患者走的尽可能远为目标,然而,特定的步行指令对患者6MWT测定的影响尚不清楚。方法:纳入肺动脉高压(pulmonaryarterialhypertension,PAH)、特发性肺间质纤维化(idiopathicpulmonaryfibrosis,IPF)和其他类型的间质性肺疾病(interstitiallungdisease,ILD)患者, | 刘莉 叶鹏 Weir NA Brown AW Shlobin OA Smith MA Reffett T Battle E Ahmad S Nathan SD | 2014 | 中华高血压杂志2014，22，2： | 13 |
| 8 | Applicability of five models to simulate water infiltration into soil with added biochar显示文摘As a soil amendment, biochar can reduce soil bulk density, increase soil porosity, and alter soil aggregates and thus affect the infiltration. Researchers have proposed and revised several theoretical models to describe the process of soil infiltration. Although these models have been successfully used to evaluate the soil infiltration in different scenarios in agricultural fields, little effort has been devoted to assess their performances in arid and semi-arid soils after the addition of biochar. A laboratory experiment was performed to study the infiltration characteristics of two typical Loess Plateau soils at three particle sizes(2–1, 1–0.25, and <0.25 mm) and five biochar application amounts(0, 10, 50, 100, and 150 g/kg). The performance of five models(i.e., the Philip model, Kostiakov model, Mezencev model, USDA-NRCS model, and Horton model) in simulating the infiltration process was then evaluated based on the adjusted coefficient of determination and a reduced Chi-Square test. Results indicated that the Horton model best simulated the water-infiltration process in an aeolian sandy soil with added biochar. However, the Mezencev model best simulated the infiltration process in a loamy clay soil(Eum-Orthic Anthrosol). The three-parameter model, i.e., Mezencev and Horton models can better describe the relationship between cumulative infiltration and infiltration time. In conclusion, biochar reduced the soil infiltration capacity of the aeolian sandy soil and increased that of the Eum-Orthic Anthrosol. | WANG Tongtong Catherine E STEWART MA Jiangbo ZHENG Jiyong ZHANG Xingchang | 2017 | Journal of Arid Land2017，9，5： | 9 |
| 9 | Sol-gel derived HA/TiO_2 double coatings on Ti scaffolds for orthopaedic applications显示文摘Hydroxyapatite/titania (HA/TiO2) double layers were coated onto Ti scaffolds throughout for orthopaedic applications by sol-gel method. Differential scanning calorimetry (DSC), thermogravimetric analysis (TG) and X-ray diffractometry (XRD) were used for the characterisation of the phase transformations of the dried gels and coated surface structures. Scanning electron microscope (SEM) equipped with energy dispersive spectrometry (EDS) was used for the observation and evaluation of the morphology and phases of the surface layers and for the assessment of the in vitro tests. The in vitro assessments were performed by soaking the HA/TiO2 double coated samples into the simulated body fluid (SBF) for various periods. The TiO2 dipping-coating method at a speed of 12 cm/min, followed by a heat treatment at 600 ℃ for 20 min. The HA la lyaeyre wr wasa ssu cbosaetqeude bnytl ya dipping-coated on the outer surface at the same speed and then heat-treated at difference temperatures. The results indicat that the HA phase begins to crystallize after a heat treatment at 560 ℃. The crystallinity increases obviously at 760 ℃. SEM observations find no delamination or crack at the interfaces of HA/TiO2 and TiO2/Ti. The HA/TiO2 coated Ti scaffolds displays excellent bone-like apatite forming ability when it is soaked into SBF. Ti scaffolds after HA/TiO2 double coatings can be anticipated as promising implant materials for orthopaedic | XU W HU W Y LI M H MA Q Q P. D. HODGSON WEN C E | 2006 | 中国有色金属学会会刊:英文版2006，16，B01： | 5 |
| 10 | Rice re-cultivation in southern China: An option for enhanced climate change resilience in rice production显示文摘在南部的中国种的瑞斯说明在播种面积的 94% 总数和在生产的 88% 总数,它非常与中国食物有关系安全。由于在在空间 / 时间的分发的水可获得性和米饭生长之间的延长冲突,然而,米饭生产在 16%22% 的面积受不了季节的干旱,它损害食物生产能力和食物安全。与米饭和惯例集中于季节的干旱的空间分发适应它,并且基于平衡的水的分析供应为并且在 19812030 期间在成长季节规模由米饭要求,这份报纸估计变化在在变化气候下面的米饭生产的过程的季节的干旱以后,并且鉴别为气候的一般米饭重新耕作选择改变改编。一些结论能如下被得出。( 1 )瑞斯在季节的干旱建议衰落,与早季节米饭(早米饭此后)由 12,500 km2 ,由 80,000 km2 的中间的季节米饭(中间的米饭),和由 25,000 km2 的特别地迟了的季节米饭(迟了的米饭),它占几乎20%它的栽培面积。由于气候变化,在生产区域的主要米饭的季节的干旱趋于一般来说减轻,这被显示,迟了的季节米饭特别地。(2 ) 未来气候变化在在中国生产区域的米饭在水资源的空间 / 时间的分发上引起重要影响。为 rice-re-cultivation 基于预先设计的改编行动,米饭耕作模式经历在 19812000 和 20012030 之间的重要改变。在东方贵州和西方的湖南,单个早正的单个干燥耕作的模式被变成两倍收割。在东方湖南,干燥收割的模式加单个干燥耕作早被变成单身者。在北安徽,收割的干燥耕作的模式被变成中间的米饭。所有这些以后为米饭生产针对水的潜在的足够的可获得性。(3 ) 在这份报纸开发的瑞斯重新耕作模式帮助重新平衡对使用空间分析工具使米饭生长适应变化的米饭生长的水需求和供应从空间观点浇可获得性,并且找到响应气候的制片人友好的重新耕作选择改变的米饭。 | MA Xin WU Shaohong LI Yu'e ZHANG Xueyan GAO Qingzhu WU Yang | 2013 | Journal of Geographical Sciences2013，23，1： | 5 |
| 11 | ^(226)Ra evidence for the ecosystem shift over the past 40 years in the North Pacific Subtropical Gyre显示文摘Surface seawater was collected for ^(226)Ra measurement in the North Pacific Subtropical Gyre from July to October, 1999 and October to December, 2003. Combined with the historical data reported for this sea area, a declined trend of surface ^(226)Ra concentrations was observed since 1960s, indicating the ecosystem shift in response to global warming. On one side, the enhanced stratification of the upper water column resulting from global warming reduced the ^(226)Ra input from the depth, on the other, the temporal increase of biological production resulting from the climate-related ecosystem structure change strengthened the ^(226)Ra removal from the surface ocean. Both the physical and biological processes resulted in the decrease of surface ^(226)Ra concentrations in the North Pacific Subtropical Gyre. The temporal trend of surface ^(226)Ra concentrations was consistent with the trends of chlorophyll a, silicate, phosphate and primary production previously reported. This study provided ^(226)Ra evidence for the ecosystem shift under global change. | YANG JunHong CHEN Min QIU YuSheng LI YanPing MA Qiang LUE E ZHANG Run HUANG YiPu | 2007 | Chinese Science Bulletin2007，52，6： | 5 |
| 12 | A comparative analysis of optimization and generalization properties of two-layer neural network and random feature models under gradient descent dynamics显示文摘A fairly comprehensive analysis is presented for the gradient descent dynamics for training two-layer neural network models in the situation when the parameters in both layers are updated.General initialization schemes as well as general regimes for the network width and training data size are considered.In the overparametrized regime,it is shown that gradient descent dynamics can achieve zero training loss exponentially fast regardless of the quality of the labels.In addition,it is proved that throughout the training process the functions represented by the neural network model are uniformly close to those of a kernel method.For general values of the network width and training data size,sharp estimates of the generalization error are established for target functions in the appropriate reproducing kernel Hilbert space. | Weinan E Chao Ma Lei Wu | 2020 | Science China Mathematics2020，63，7： | 4 |
| 13 | Influence of particle composition on thorium scavenging in the marginal China seas显示文摘Thorium-234 and particle composition (organic matter, biogenic silica, carbonate and lithogenic component) were examined in the East China Sea (ECS) and the northern South China Sea (NSCS) in order to constrain the particle types scavenging thorium isotopes. Good positive correlations be-tween particulate organic matter (POM) or carbonate and thorium-234 in suspended particulate matter (SPM) indicates that POM and carbonate are efficient to scavenge thorium-234. No relation-ship between biogenic silica and thorium-234 suggests that geochemical behavior of thorium-234 may be not influenced by biogenic silica. A simple model was used to evaluate the affinity of thorium-234 to different particle components. The results show that POM is the most efficient scavenger for thorium-234 in the ECS and the NSCS, followed by carbonate. The authors’ re-sults lend support to the utility of thorium-234 as a proxy of POC and carbonate in the upper layer. However, the strong dependence of thorium scavenging on particle composition challenges thorium-230 as a constant flux proxy. | YANG Weifeng CHEN Min CAO Jianping QIU Yusheng ZHANG Run MA Qiang TONG Jinlu YANG Junhong YANG Zhi LUE E | 2009 | Acta Oceanologica Sinica2009，28，2： | 4 |
| 14 | Multiple sgRNAs facilitate base editingmediated i-stop to induce complete and precise gene disruption显示文摘Dear Editor,Gene editing is a process to introduce desired changes into targeted loci of genomic DNA.Recently,type II clustered regularly in terspaced short palindromic repeats-associated Cas9 endonuclease(CRISPR/Cas9)system has been demonstrated as a versatile tool for engineering eukaryote genome(Hsu et al.,2014),such as in mice(Zuo et al.,2017). | Kun Jia Zongyang Lu Fei Zhou Zhiqi Xiong Rui Zhang Zhiwei Liu Yu'e Ma Lei He Cong Li Zhen Zhu Dejing Pan Zhengxing Lian | 2019 | Protein & Cell2019，10，11： | 3 |
| 15 | 地中海膳食干预研究中来自胆碱通路的血浆代谢物与心血管病风险的关系显示文摘血浆甜菜碱水平以及胆碱代谢水平与主要心血管病终点之间的联系仍不清楚。研究者评估了胆碱通路的代谢物与偶发心血管病风险以及地中海膳食干预的潜在调节效应之间的相关性。 | 黄洁 叶鹏 Guasch-Ferré M Hu FB Ruiz-Canela M Bulló M Toledo E Wang DD Corella D Gómez-Gracia E Fiol M Estruch R Lapetra J Fitó M Arós F Serra-Majem L Ros E Dennis C Liang L Clish CB Martínez-González MA Salas-Salvadó J | 2017 | 中华高血压杂志2017，25，12： | 2 |
| 16 | Machine learning from a continuous viewpoint,I显示文摘We present a continuous formulation of machine learning,as a problem in the calculus of variations and differential-integral equations,in the spirit of classical numerical analysis.We demonstrate that conventional machine learning models and algorithms,such as the random feature model,the two-layer neural network model and the residual neural network model,can all be recovered(in a scaled form)as particular discretizations of different continuous formulations.We also present examples of new models,such as the flow-based random feature model,and new algorithms,such as the smoothed particle method and spectral method,that arise naturally from this continuous formulation.We discuss how the issues of generalization error and implicit regularization can be studied under this framework. | Weinan E Chao Ma Lei Wu | 2020 | Science China Mathematics2020，63，11： | 2 |
| 17 | Influence of pesticides and alfalfa on soilbiological properties显示文摘Several biochemical parameters, such as respiration rate (RIP) , biomass - C oxygen demand , andATP reflecting microorganism biomass and activities were determined. All soil samples were incubated at22℃ , 14. 5 ℃ for 60, 192 and 480h, respectively. All th | Ma Ruixia Sun Sien(Research Center for Eco Environmental Sciences , Chinese Academy of Sciences . Beijing 100085 , China) R. Hantschel, F. Beese(GSF - Institut fur the ecologic, Ingolstter Landstraβe 1 , D-8042 Neuherberg, Germany) | 1995 | Journal of Environmental Sciences1995，7，2： | 2 |
| 18 | 4-Phenylbutyric acid accelerates rehabilitation of barrier function in IPEC-J2 cell monolayer model显示文摘As the first line of defence against pathogens and endotoxins crossing the intestine-blood barrier,the intestinal epithelial barrier plays a determinant role in pigs’health and growth.4-Phenylbutyric acid(4-PBA),an aromatic fatty acid,was reported to benefit homeostasis of endoplasmic reticulum and protein synthesis.However,whether 4-PBA affects intestinal epithelial barrier function in pigs is unknown.This study aimed to explore the effects of 4-PBA on the intestinal barrier function,using in vitro models of well-differentiated intestinal porcine epithelial cell(IPEC-J2)monolayers in the transwell plates.Cell monolayers with or without 4-PBA(1.0 mmol/L)treatment were challenged with physical scratch,deoxynivalenol(DON,2.0μg/mL,48 h),and lipopolysaccharide(LPS,5.0μg/mL,48 h),respectively.Transepithelial electrical resistance(TEER)and fluorescein isothiocyanate-dextran(FD-4)permeability were measured to indicate barrier integrity and permeability.Real-time PCR and Western blot were conducted to determine relative gene and protein expressions of tight junction proteins.As expected,physical scratch,DON,and LPS challenges decreased TEER and increased FD-4 permeability.4-PBA treatment accelerated cell mitigation and rehabilitation of the physical scratch-damaged intestinal epithelial barrier but did not alleviate DON or LPS induced barrier damage.However,once 48-h DON and LPS challenges were removed,rehabilitation of the epithelial barrier function of IPEC-J2 monolayer was accelerated by the 4-PBA treatment.Also,the relative gene and protein expressions of zonula occludens-1(ZO-1),occludin,and claudin-1 were further upregulated by the 4-PBA treatment during the barrier rehabilitation.Taken together,4-PBA accelerated the IPEC-J2 cell monolayer barrier recovering from physical scratch,DON-,and LPS-induced damage,via enhancing cell mitigation and expressions of tight junction proteins. | Qian Jiang Jie Yin Jiashun Chen Xiaokang Ma Miaomiao Wu Xilong Li Kang Yao Bi'e Tan Yulong Yin | 2021 | Animal Nutrition2021，，4： | 2 |
| 19 | Linear Complexity of Least Significant Bit of Polynomial Quotients显示文摘Binary sequences with large linear complexity have been found many applications in communication systems.We determine the linear complexity of a family of p^2-periodic binary sequences derived from polynomial quotients modulo an odd prime p.Results show that these sequences have high linear complexity,which means they can resist the linear attack method. | ZHAO Chun'e MA Wenping YAN Tongjiang SUN Yuhua | 2017 | Chinese Journal of Electronics2017，26，3： | 2 |
| 20 | Finite element modeling assumptions impact on seismic response demands of MRF-buildings显示文摘Recent seismic events have raised concerns over the safety and vulnerability of reinforced concrete moment resisting frame 'RC-MRF' buildings. The seismic response of such buildings is greatly dependent on the computational tools used and the inherent assumptions in the modelling process. Thus, it is essential to investigate the sensitivity of the response demands to the corresponding modelling assumption. Many parameters and assumptions are justified to generate effective structural finite element(FE) models of buildings to simulate lateral behaviour and evaluate seismic design demands. As such, the present study focuses on the development of reliable FE models with various levels of refinement. The effects of the FE modelling assumptions on the seismic response demands on the design of buildings are investigated. the predictive ability of a FE model is tied to the accuracy of numerical analysis; a numerical analysis is performed for a series of symmetric buildings in active seismic zones. The results of the seismic response demands are presented in a comparative format to confirm drift and strength limits requirements. A proposed model is formulated based on a simplified modeling approach, where the most refined model is used to calibrate the simplified model. | Shehata E Abdel Raheem Ahmed K Abdel Zaher Ahmed MA Taha | 2018 | Earthquake Engineering and Engineering Vibration2018，17，4： | 2 |
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