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| 1 | Treatment of laryngopharyngeal reflux disease: A systematic review显示文摘BACKGROUNG For a long time,laryngopharyngeal reflux disease(LPRD)has been treated by proton pump inhibitors(PPIs)with an uncertain success rate.AIM To shed light the current therapeutic strategies used for LPRD in order to analysis the rationale in the LPRD treatment.METHODS Three authors conducted a PubMed search to identify papers published between January 1990 and February 2019 about the treatment of LPRD.Clinical prospective or retrospective studies had to explore the impact of medical treatment(s)on the clinical presentation of suspected or confirmed LPRD.The criteria for considering studies for the review were based on the population,intervention,comparison,and outcome framework.RESULTS The search identified 1355 relevant papers,of which 76 studies met the inclusion criteria,accounting for 6457 patients.A total of 64 studies consisted of empirical therapeutic trials and 12 were studies where authors formally identified LPRD with pH-monitoring or multichannel intraluminal impedance-pH monitoring(MII-pH).The main therapeutic scheme consisted of once or twice daily PPIs for a duration ranged from 4 to 24 wk.The most used PPIs were omeprazole,esomeprazole,rabeprazole,lansoprazole and pantoprazole with a success rate ranging from 18%to 87%.Other composite treatments have been prescribed including PPIs,alginate,prokinetics,and H2 Receptor antagonists.CONCLUSION Regarding the development of MII-pH and the identification of LPRD subtypes(acid,nonacid,mixed),future studies are needed to improve the LPRD treatment considering all subtypes of reflux. | Jerome R Lechien Francois Mouawad Maria R Barillari Andrea Nacci Seyyedeh Maryam Khoddami Necati Enver Sampath Kumar Raghunandhan Christian Calvo-Henriquez Young-Gyu Eun Sven Saussez | 2019 | World Journal of Clinical Cases2019，7，19： | 9 |
| 2 | CDX2 protein expression compared to alcian blue staining in the evaluation of esophageal intestinal metaplasia显示文摘AIM:To compare the sensitivity and specificity of CDX2 and alcian blue(AB) p H 2.5 staining in identifying esophageal intestinal metaplasia.METHODS:One hundred and ninty-nine biopsies from 186 patients were retrospectively reviewed and categorized as Barrett's esophagus(BE)(n =108); non-Barrett's esophagus(NBE)(n =48); columnar blue cells(CB) and esophageal glands(EG)(n =43).The biopsies were stained with AB and immunostained for CDX2 using a mouse monoclonal antibody from Biogenex(clone CDX2-88) and the Ventana Discovery X automated immunostainer.The positive and negative predictive value of each group was used to determine the predictive power of CDX2 and AB in diagnosing intestinal metaplasia.RESULTS:All of the 108 BE biopsies(100%) were positive for AB and 102 of them(94.4%) were positive for CDX2.The six BE patients(5.6%) who failed to stain with CDX2 were found to have lost the focus of intestinal metaplasia upon deeper sectioning for immunostaining.Both AB and CDX2 were negative in 43 out of 48(89.6%) NBE cases.Five NBE patients(10.4%) were falsely positive for AB due to the presence of EG and CB in these biopsies.These cases were all CDX2 negative.In addition,5 AB negative NBE were found to be CDX2 positive.Based on these results the CDX2 immunostain had similar sensitivity but higher specificity(100% vs about 91%) than AB in detecting intestinal type metaplasia in these samples.Our data shows that CDX2 has a better PPV in detecting intestinal metaplasia as compared to AB(95.6% vs 71.5%,respectively).CONCLUSION:CDX2 has a better positive predictive value than AB in detecting intestinal metaplasia.CDX2may be useful when challenged by gastro-esophageal biopsies containing mimikers of BE. | Dennis R Johnson Maisoun Abdelbaqui Maryam Tahmasbi Zoltan Mayer Hung-Wei Lee Mokenge P Malafa Domenico Coppola | 2015 | World Journal of Gastroenterology2015，21，9： | 2 |
| 3 | Livistona ex-tract inhibits angiogenesis and cancer growth显示文摘 | Sartippour Maryam R Liu Canhui Shao Zhiming | 2001 | Oncology Reports2001，8，6： | 1 |
| 4 | Design and fabrication of a large-scale oedometer显示文摘The most common apparatus used to investigate the load-deformation parameters of homogeneous fine-grained soils is a Casagrande-type oedometer. A typical Casagrande oedometer cell has an internal diameter of 76 mm and a height of 19 mm.However, the dimensions of this kind of apparatus do not meet the requirements of some civil engineering applications like studying load-deformation characteristics of specimens with large-diameter particles such as granular materials or municipal solid waste materials. Therefore, it is decided to design and develop a large-scale oedometer with an internal diameter of 490 mm. The new apparatus provides the possibility to evaluate the load-deformation characteristics of soil specimens with different diameter to height ratios. The designed apparatus is able to measure the coefficient of lateral earth pressure at rest. The details and capabilities of the developed oedometer are provided and discussed. To study the performance and efficiency, a number of consolidation tests were performed on Firoozkoh No. 161 sand using the newly developed large scale oedometer made and also the 50 mm diameter Casagrande oedometer. Benchmark test results show that measured consolidation parameters by large scale oedometer are comparable to values measured by Casagrande type oedometer. | Maryam Mokhtari Nader Shariatmadari Ali Akbar Heshmati R Hossein Salehzadeh | 2015 | Journal of Central South University2015，22，3： | 1 |
| 5 | Effectiveness of educational programs based on Pender's theory on the health and symptoms in patients with obsessive-compulsive disorder显示文摘 | Maryam R Tahereh A Leila N | 2012 | Life Science2012，9，4： | 1 |
| 6 | Reduction of af- latoxin B1 in chicken feed by using Saccharomyces cerevisiae, Rhizopus oligosporus and their combination显示文摘 | Kusumaningtyas E Widiastuti R Maryam R | 2006 | Mycopatholo- gia2006，162，4： | 1 |
| 7 | Assignment ofEigenvalue Sensitivities from Receptanee Measurements显示文摘 | JOHN E M MARYAM G T YITSHAK M R | 2009 | Mechanical Systems and Signal Processing2009，23，： | 1 |
| 8 | Cardiac troponin T levels of umbilical cord in neonates with abnormal fetal heart rate显示文摘 | Shiva R Maryam R Hajie B | 2013 | Iran J Pediatr2013，23，1： | 1 |
| 9 | Recanalization therapy for acute ischemic stroke, part 1: surgical emboletomy and cheemical thtombolysis 显示文摘 | Aaeed A Maryam R Michael F | 2011 | Neurosurg Rev2011，34，11： | 1 |
| 10 | Evaluation of salivary tumor necrosis factor-alpha in patients with the chronic periodontitis: A case-control study 显示文摘 | Yousefimanesh H Maryam R Mahmoud J | 2013 | J Indian SocPeriodontol2013，17，6： | 1 |
| 11 | Heavymetal in children's tooth enamel: related to autism anddisruptive behaviors 显示文摘 | MARYAM M A AGNES R L WENDY A G | 2012 | J Autism Dev Disord2012，42，： | 1 |
| 12 | Effect of different cooking methods on minerals, vitamins and nutritional quality indices of kuturnL roach (rutilus frisii kutum) 显示文摘 | Hedayat H Maryam M Masoud R | 2014 | Food Chem2014，148，： | 1 |
| 13 | Challenges and progress towards understanding the role of effectors in plant–fungal interactions显示文摘 | Maryam Rafiqi Jeffrey G Ellis Victoria A Ludowici Adrienne R Hardham Peter N Dodds | 2012 | Current Opinion in Plant Biology2012，，4： | 1 |
| 14 | Ganoderma iucidum spore extract inhibits endothelial and breast cancer cells in vitro 显示文摘 | Qing Yilu Maryam R | 2004 | Oncology Reports2004，，12： | 1 |
| 15 | Evaluation of salivary tumor necrosis factor-alpha in patients with the chronic periodontitis: A case-control study显示文摘 | Yousefimanesh H Maryam R Mahmoud J | 2013 | J Indian Soc Periodontol2013，17，6： | 1 |
| 16 | Designing the fuzzy controller in mobile robot navigation with the presence of unknown obstacles 显示文摘 | MARYAM R MOHAMMAD H K MOHAMMAD A N | 2012 | International Journal of Intelligent Information Processing2012，3，1： | 1 |
| 17 | Recanalization therapy for acute ischemic stroke, part 1: surgical emholectomy and chemical thrombolysis 显示文摘 | Saeed A Maryam R Michael F | 2011 | Neurosurg Rev2011，34，1： | 1 |
| 18 | Capa- bility-based cellular manufacturing systems formation in dual-resource constrained settings using tabu search 显示文摘 | Maryam H Esmaeilian G R Ismail N | 2012 | Computers & Industrial Engineering2012，62，4： | 1 |
| 19 | Effects of Vitamin E and Zinc Supplementation on An- tioxidants in Beta thalassemia major 显示文摘 | MOHAMMADREZA R MARYAM A MARYAM R | 2011 | Patientslran J Pediatr2011，21，1： | 1 |
| 20 | Shear bond strength and antibacterial effects of orthodontic composite containing Ti O2nanoparticles显示文摘 | Maryam P Baratali R Mojtaba Z | 2013 | Eur J Orthod2013，35，5： | 1 |
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