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| 1 | Carbon source dependence and photostimulation of conidiatiou in Hypocrea atroviridis显示文摘 | MARTINA A F CHRISTIAN P K IRINA S D | 2008 | Applied and Enviroumental Microbiology2008，74，1： | 1 |
| 2 | Modelling respirometric tests for the assessment of kinetic and stoichiometric parameters on MBBR biofilm for municipal wastewater treatment显示文摘 | MARTINA F GIUSEPPE G GIANNI A | 2009 | Environmental Modelling & Software2009，5，5： | 1 |
| 3 | Role of the IGF system in trophoblast invasion and pre-eclampsia 显示文摘 | Irwin J C Suen L F Martina N A | 1999 | Hum Reprod1999，14，2： | 1 |
| 4 | Human amniotic fluid-derived stem cells are rejected after transplantation in the myocardium of normal, ischemic, immuno-suppressed or immuno-deficient rat 显示文摘 | Angela C Sveva B Michela P Saverio S Andrea C Lisa G Jenny T Martina P Elisabetta L Gino G Igor V Emanuele C Annalisa A Laura I Giovanni F Z Anthony A Paolo D C and Saverio S | 2007 | Journal of Molecular and Cellular Cardiology2007，42，4： | 1 |
| 5 | Wire + arc additive manufacturing显示文摘 | Williams S W Martina F Addison A C | 2015 | Materials Science and Technology2015，，： | 1 |
| 6 | Influenza B virus in seals显示文摘 | Osterhaus A D Rimmelzawaan G F Martina B E | 2000 | Science2000，288，： | 1 |
| 7 | Role of the IGF system in trophoblast invasion and preeclampsia显示文摘 | IRWENJ C SUEN L F MARTINA N A | 1999 | Hum Reprod1999，14，2： | 1 |
| 8 | Mechanical proper- ties of polymers: the influence of molecular weight and molecu- lar weight distribution显示文摘 | Martina J R Johnson J F Coopercd A R | 1972 | Journal of Macromolecular Science Part C (Polymer Reviews)1972，8，1： | 1 |
| 9 | Role of the IGF system in trophoblast invasion and preeclampsia显示文摘 | Irwen J C Suen L F Martina N A | 1999 | Hum Reprod1999，14，2： | 1 |
| 10 | Synthesis of a novel cardanol-based benzoxazine monomer and environmentally sustainable production of polymers and bin-composites显示文摘 | Cole E Maffezzoli A Mele G Martina F Mazzetto S E Tarzia A Stifanl A | 2007 | Green Chem2007，9，： | 1 |
| 11 | Spatial incoherence in phase retrieval based on focus variation 显示文摘 | A V Martina F R Chenh W K Hsiehb | 2006 | Uhramicroscopy2006，106，10： | 1 |
| 12 | Use o quillaja saponins (quillaja saponaria molina) to control acid mist in copper e- lectrowinning processes part 1: laboratory scale evaluation 显示文摘 | R M Martina A F Oterob A Cruzc | 2005 | Hydrornetallurgy2005，77，： | 1 |
| 13 | Use of quillaja saponins (quillaja saponaria molina) to control acid mist in copper e- lectrowinning processes part 2: pilot plant and industrial scale evaluation显示文摘 | R M Martina A F Oterob A Cruze | 2005 | Hydrometallurgy2005，77，： | 1 |
| 14 | Transcriptional regulation of tenascin-W by TGF-beta signaling in the bone metastatic niche of breast cancer cells显示文摘 | Chiovaro F Martina E Bottos A | 2015 | Int J Cancer2015，137，8： | 1 |
| 15 | The V433M va- riant of the CYP4F2 is associated with ischemic stroke in male swedes beyond its effect on blood pressure 显示文摘 | Cristiano F Martina M Peter A | 2008 | Hypertension2008，52，2： | 1 |
| 16 | Platelet cNOS activity is reduced in patients with IDDM and NIDDM 显示文摘 | BRUNO G A TRUCCO F | 1998 | Thromb Haemost1998，79，3： | 1 |
| 17 | Catalase activity measure-ements in suspended aerobic biomass and soil samples 显示文摘 | GUWYA A MARTINA S R HAWKESB F R | 1999 | Enzyme and Microbial Technology1999，25，： | 1 |
| 18 | A comparative study of additive manufacturing techniques: residual stress and microstructural analysis of CLAD and WAAM printed Ti- 6A14V components 显示文摘 | Szost B A Terzi S Martina F | 2016 | Materials and Design2016，89，： | 1 |
| 19 | Effect of Aspergillus niger prolyl endopeptidase in patients with celiac disease on a long-term gluten-free diet显示文摘BACKGROUND The gluten-free diet(GFD)has limitations,and there is intense research in the development of adjuvant therapies.AIM To examine the effects of orally administered Aspergillus niger prolyl endopeptidase protease(AN-PEP)on inadvertent gluten exposure and symptom prevention in adult celiac disease(CeD)patients following their usual GFD.METHODS This was an exploratory,double-blind,randomized,placebo-controlled trial that enrolled CeD patients on a long-term GFD.After a 4-wk run-in period,patients were randomized to 4 wk of two AN-PEP capsules(GliadinX;AVI Research,LLC,United States)at each of three meals per day or placebo.Outcome endpoints were:(1)Average weekly stool gluten immunogenic peptides(GIP)between the run-in and end of treatments and between AN-PEP and placebo;(2)celiac symptom index(CSI);(3)CeD-specific serology;and(4)quality of life.Stool samples were collected for GIP testing by ELISA every Tuesday and Friday during run-ins and treatments.RESULTS Forty patients were randomized for the intention-to-treat analysis,and three were excluded from the per-protocol assessment.Overall,628/640(98.1%)stool samples were collected.GIP was undetectable(<0.08μg/g)in 65.6%of samples,and no differences between treatment arms were detected.Only 0.5%of samples had GIP concentrations sufficiently high(>0.32μg/g)to potentially cause mucosal damage.Median GIP concentration in the AN-PEP arm was 44.7%lower than in the run-in period.One-third of patients exhibiting GIP>0.08μg/g during run-in had lower or undetectable GIP after AN-PEP treatment.Compared with the run-in period,the proportion of symptomatic patients(CSI>38)in the AN-PEP arm was significantly lower(P<0.03).AN-PEP did not result in changes in specific serologies.CONCLUSION This exploratory study conducted in a real-life setting revealed high adherence to the GFD.The AN-PEP treatment did not significantly reduce the overall GIP stool concentration.However,given the observation of a significantly lower prevalence of patients with severe symptoms in the AN-PEP arm,further clinical research is warranted. | Juan Pablo Stefanolo Verónica Segura Martina Grizzuti Abel Heredia Isabel Comino Ana Florencia Costa Roberto Puebla María Paz Temprano Sonia Isabel Niveloni Gabriel de Diego María E Oregui Edgardo Gustavo Smecuol Mauricio C de Marzi Elena F Verdú Carolina Sousa Julio César Bai | 2024 | World Journal of Gastroenterology2024，30，11： | 0 |
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