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| 1 | Radical resection of pancreatic cancer显示文摘BACKGROUND: Pancreatic adenocarcinoma (PCa) is a disease with dismal prognosis, and the only possibility of cure, albeit small, is based on the combination of complete resection with negative histopathological margins (R0 resection) with adjuvant treatment. Therefore, a lot of effort has been made during the last decade to assess the role of extensive surgery in both local recurrence and survival of patients with PCa. DATA SOURCES: Medline search and manual cross- referencing were utilized to identify published evidence- based data for PCa surgery between 1973 and 2006, with emphasis to feasibility, efficacy, long-term survival, disease free survival, recurrence rates, pain relief and quality of life. RESULTS: Extended surgery is safe and feasible in high volume surgical centers with comparable short-term results. Organ preserving surgery is a main goal because of quality of life reasons and is performed whenever possible from the tumor extent. Concerning long-term survival major vein resection does not adversely affect outcome. To date, there are no changes in long-term survival attributed to the extended lymph node dissection. However, there is a benefit in locoregional control with fewer local recurrences and extended lymphadenectomy allows better staging for the disease. CONCLUSIONS: Extended PCa surgery is safe and feasible despite the inconclusive results in patient's survival benefit. In the future, appropriately powered randomized trials of standard vs. extended resections may show improved outcomes for PCa patients. | Alexander Koliopanos C Avgerinos Athanasios Farfaras C Manes Christos Dervenis | 2008 | Hepatobiliary & Pancreatic Diseases International2008，7，1： | 4 |
| 2 | Vascular risk factors and diabetic neurop- athy显示文摘 | Tesfaye S Chaturvedi N Eaton S E Ward J D Manes C Iones- cu-Tirgoviste C | 2005 | N Engl J Med2005，3521，： | 1 |
| 3 | 显示文摘 | Sankapal B R Mane R S Lokhande C D | 2000 | Mater Chem Phys2000，63，： | 1 |
| 4 | Liquid chromatography-electrospray quadrupole ion-trap mass spectrometry of nine pesticides in fruits显示文摘 | SOLER C MANES J PicoYolanda | 2004 | Journal of Chromatography A2004，1048，1： | 1 |
| 5 | RNA-seq= an assessment of technical reproducibility and com- parison with gene expression arrays显示文摘 | Marioni J C Mason C E Mane S M | 2008 | Genome Re- search2008，18，： | 1 |
| 6 | Cutting edge: TNF-induced microRNAs regulate TNF-induced expression of E-selectin and intercellular adhesion molecule-1 on human endothelial cells: feedback control of inflammation 显示文摘 | Suarez Y Wang C Manes TD | 2010 | J Immunol2010，184，1： | 1 |
| 7 | 查看详情显示文摘 | Haynam C A Wegner P J Auerbach J M Bowers M W Dixit S N Erbert G V Heestand G M Henesian M A Hermann M R Jancaitis K S Manes K R Marshall C D Mehta N C Menapace J Moses E Murray J R Nostrand M C Orth C D Patterson R SacksR A Shaw M J Spaeth M Sutton S B W | | 0，，： | 1 |
| 8 | Routine application using single quadrupole liquid chromatography-mass spectrometry to pesticides analysis in citrus fruits 显示文摘 | Soler C Manes J Pico Y | 2005 | Journal of Chromatography A2005，1088，12： | 1 |
| 9 | A new approach to state observation of nonlinear systems with delayed output 显示文摘 | GERMANI A MANES C PEPE P | 2002 | IEEE Trans Autom Control2002，47，1： | 1 |
| 10 | Determination of pesticide residues in fruits and vegetables 显示文摘 | Torres C M Pico Y Manes J | 1996 | Journal of Chromatogram Analysis1996，，754： | 1 |
| 11 | Evaluation of matrix solid- phase dispersion(MSPD) extraction for multi-mycotoxin determination in different flours using LC- MS/MS 显示文摘 | Rubert J Soler C Manes J | 2011 | Talanta2011，85，1： | 1 |
| 12 | Determination of pesticide residues infruits and vegetables显示文摘 | Terres C M Pico Y Manes J | 1996 | J ChromtogrA1996，754，： | 1 |
| 13 | Journal of Physical Chemistry 显示文摘 | Chiou C Manes M | 1974 | 78(6): 622-6261974，78，6： | 1 |
| 14 | Analysis of pesticides residues in fruit and vegetables by matrix solid phase dispersion(MSPD)and different gas chromatography dement-selective deteetors显示文摘 | Tortes C M Pico Y Manes J | 1995 | Chormatographia1995，41，1112： | 1 |
| 15 | Routine Application Using Single Quadrupole Liquid Chromatography-mass Spectro Metry to Pesticides Analysis in Citrus Fruits显示文摘 | Soler C Manes J Picó Y | 2005 | Journal of Chromatography A2005，，1088： | 1 |
| 16 | Analysis of pesticide residues in fruit and vegetable by matrix solid-phase dispersion (MSPD) and different gas chromatography element-selective detectors 显示文摘 | Torres C M Pico Y Manes J | 1995 | J Chromatography A1995，41，1112： | 1 |
| 17 | Determination of fungicide residues in fruits and vegetables by liquid chromatography atmospheric pressure chemical ionization mass spectrometry 显示文摘 | Blasco C Pico Y Manes J Font G | 2002 | Journal of Chromatography A2002，947，2： | 1 |
| 18 | Partition-limited model for the plant uptake of organic contaminants from soil and water显示文摘 | Chiou C T Sheng G Y Manes M A | 2001 | Environ Sci Technol2001，35，： | 1 |
| 19 | Determination of Fungicide Residues in Fruits and Vegetables by Liquid Chromatography-atmospheric Pressure Chemical Ionization Mass Spectrometry显示文摘 | Blasco C Picó Y Manes J | 2002 | Journal of Chromatography A2002，，947： | 1 |
| 20 | A new approach to state observation of nonlinear systems with delayed output显示文摘 | GERMANI A MANES C PEPE P | 2001 | IEEE Trans on Automatic Control2001，46，7： | 1 |
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