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| 1 | Non-pharmacological cognitive intervention for aging and dementia:Current perspectives显示文摘In recent years, cognitive difficulties associated with normal aging and dementia have been receiving increased attention from both public and scientific communities. With an increase in overall lifespan, promoting healthy cognition has become a priority and a necessity for minimizing and preventing individual and societal burdens associated with cognitive dysfunctions in the elderly. The general awareness concerning the efficacy of preventive(e.g., lifestyles) and palliative treatment strategies of cognitive impairments, related to either healthy or unhealthy trajectories in cognitive aging, is continuously rising. There are several therapeutic strategies which can be broadly classified as either pharmacological or non-pharmacological/psychosocial. In face of the modest evidence for success of pharmacological treatments, especially for dementia related impairments, psychosocial interventions are progressively considered as a complementary treatment. Despite the relative spread of psychosocial interventions in clinical settings, research in this area is rather scarce with evidence for success of these therapies remaining controversial. In this work we provide an evidence based perspective on cognitive intervention(s) for healthy aging, pre-dementia(mild cognitive impairment), and dementia populations. Current evidence and future directions for improving cognitive functions in the elderly are discussed as well. | Jorge Alves Rosana Magalh?es álvaro Machado óscar F Gon?alves Adriana Sampaio Agavni Petrosyan | 2013 | World Journal of Clinical Cases2013，1，8： | 8 |
| 2 | 螺内酯与可乐定作为难治性高血压第4种治疗药物的比较:难治性高血压的最佳治疗随机研究显示文摘该研究旨在通过一个多中心随机试验对作为难治性高血压患者的第4种治疗药物的螺内酯与可乐定进行比较。采用药丸计数评估药物治疗依从性。难治性高血压患者(定义为包括1种利尿剂在内的3种药物治疗12周,诊室及动态血压监测血压仍未控制)随机给予螺内酯(12.5~50 mg/d)或可乐定(0.1~0.3mg,2次/d)继续治疗12周。 | Krieger EM Drager LF Giorgi DMA Pereira AC Barreto-Filho JAS Nogueira AR Mill JG Lotufo PA Amodeo C Batista MC Bodanese LC Carvalho ACC Castro I Chaves H Costa EAS Feitosa GS Franco RJS Fuchs FD Guimarāes AC Jardim PC Machado CA Magalhāes ME Mion D Jr Nascimento RM Nobre F Nóbrega AC Ribeiro ALP Rodrigues-Sobrinho CR Sanjuliani AF Teixeira MDCB Krieger JE ReHOT Investigators 赵狄 练桂丽 | 2018 | 中华高血压杂志2018，26，3： | 7 |
| 3 | 定期运动有助于改善高血压患者蛋白质稳态、炎症和血管活性显示文摘体育锻炼是一种公认的非药物控制血压的策略,除了降低血压外,运动还能对高血压患者的炎症特征、自主功能、内皮功能和抗氧化状态产生积极的影响。但其对高血压患者的蛋白质稳态的影响尚不清楚。已有动物研究表明,运动训练干预可以改善蛋白质质量控制机制,但在动物模型中报告的积极作用仍有待于在人类身上得到证实。本研究旨在根据报告的运动习惯,评估患高血压成年人的蛋白质稳态,生活质量以及炎症、氧化应激和血管活性生物标记物状态。 | Teixeira M Gouveia M Duarte A Ferreira M Simões MI Conceição M Silva G Magalhães S Ferreira R Nunes A Vieira SI Ribeiro F 周卫(译) 叶鹏(审校) | 2020 | 中华高血压杂志2020，28，12： | 2 |
| 4 | Cardiovascular effects of eugenol,a phenolic compound present in many plant essential oils,in normotensive rats显示文摘 | Lahlou S Interaminense L F Magalhes P J | 2004 | J Cardiovasc Pharmacol2004，43，2： | 1 |
| 5 | Geographic distribution of vacA allelic types of Helicobacter pylori显示文摘 | Leen–Jan Van Doorn Céu Figueiredo Francis Mégraud Salvador Pena Peter Midolo Dulciene Maria De Magalh?es Queiroz Fátima Carneiro Bart Vanderborght Maria Da Glória F. Pegado Ricardo Sanna Wink De Boer Peter M. Schneeberger Pelayo Correa Enders K.W. Ng John | 1999 | Gastroenterology1999，，4： | 1 |
| 6 | Nucleation and growth of mullite whiskers from lanthanum-doped aluminosilicate melts显示文摘 | Regiani I Magalh(a)es W L E De Souza D P F Paiva-Santos CO De Souza M F | | 0，，01： | 1 |
| 7 | Non-enzymatic browning in clarified cashew apple juice during thermal treatment:kinetics and process control显示文摘 | DAMASCENO L F FERNANDES F A N MAGALH(A)ES M | | 0，，1： | 1 |
| 8 | Apolipoprotein E polymorphism influences orthotopic liver transplantation outcomes in patients with hepatitis C virus-induced liver cirrhosis显示文摘BACKGROUND Hepatitis C virus(HCV)infection is responsible for a chronic liver inflammation,which may cause end-stage liver disease and hepatocellular carcinoma.Apolipoprotein E(protein:ApoE,gene:APOE),a key player in cholesterol metabolism,is mainly synthesized in the liver and APOE polymorphisms may influence HCV-induced liver damage.AIM To determine whether APOE alleles affect outcomes in HCV-infected patients with liver cirrhosis following orthotopic liver transplantation(OLT).METHODS This was a cohort study in which 179 patients,both genders and aged 34-70 years,were included before or after(up to 10 years follow-up)OLT.Liver injury severity was assessed using different criteria,including METAVIR and models for endstage liver disease.APOE polymorphisms were analyzed by quantitative real-time polymerase chain reaction.RESULTS The APOE3 allele was the most common(67.3%).In inflammation severity of biopsies from 89 OLT explants and 2 patients in pre-transplant,the degree of severe inflammation(A3F4,0.0%)was significantly less frequent than in patients with minimal and moderate degree of inflammation(≤A2F4,16.2%)P=0.048,in patients carrying the APOE4 allele when compared to non-APOE4.In addition,a significant difference was also found(≤A2F4,64.4%vs A3F4,0.0%;P=0.043)and(A1F4,57.4%vs A3F4,0.0%;P=0.024)in APOE4 patients when compared to APOE3 carriers.The fibrosis degree of the liver graft in 8 of 91 patients and the lack of the E4 allele was associated with more moderate fibrosis(F2)(P=0.006).CONCLUSION Our results suggest that the E4 allele protects against progression of liver fibrosis and degree of inflammation in HCV-infected patients. | José Carlos Rodrigues Nascimento Lianna C Pereira Juliana Magalhães C Rêgo Ronaldo P Dias Paulo Goberlânio B Silva Silvio Alencar C Sobrinho Gustavo R Coelho Ivelise Regina C Brasil Edmilson F Oliveira-Filho James S Owen Pierluigi Toniutto Reinaldo B Oriá | 2021 | World Journal of Gastroenterology2021，27，11： | 1 |
| 9 | Solubility of carbon dioxide in aqueous solutions of amino acid salts显示文摘 | Portugal A F Sousa J M Magalh(a)es F D Mendes A | | 0，，09： | 1 |
| 10 | Poli-cy-based groo- ming in optical networks 显示文摘 | Verdi F L Carvalho C Magalhes M F | 2008 | Journal of Network and Systems Management2008，16，4： | 1 |
| 11 | Electronic characterization and photocatalytic properties of CdS/TiO2 semiconductor composite 显示文摘 | TRISTO J C MAGALHES F CORIO P SANSIVIERO M T C | 2006 | Journal of Photochemistry and Photobiology A: Chemistry2006，181，15： | 1 |
| 12 | Damping estimation using free decays and ambient vibration tests显示文摘 | Magalh?es F Cunha á Caetano E | 2010 | Mechanical Systems and Signal Processing2010，24，5： | 1 |
| 13 | Characterization of hemieeUulases and cellulases produced by Ceriporiopsis subvermispora grown on wood under biopulping conditions显示文摘 | Heidorne F O Magalhāes P O Ferraz A L | 2006 | Enzyme Microb Technol2006，38，： | 1 |
| 14 | Effect of feeding yeast culture on performance, health, and im- munocompetence of dairy calves显示文摘 | Magalhes V J A Susca F Lima F S | 2008 | Journal of Dairy Science2008，91，4： | 1 |
| 15 | Damping estimation using free decays and ambient vibration tests显示文摘 | Magalhes F Cunha Jr Caetano E Brincker R | 2010 | Me- chanical Systems and Signal Processing2010，24，5： | 1 |
| 16 | Carbon molecular sieve membranes from cellophane paper 显示文摘 | Campoa M C Magalhes F D Mendes A | 2010 | J Membr Sci2010，350，12： | 1 |
| 17 | Formation processes of methane-derived authigenic carbonates from the Gulf of Cadiz显示文摘 | Magalh?es V H Pinheiro L M Ivanov M K Kozlova E Blinova V Kolganova J Vasconcelos C McKenzie J A Bernasconi S M Kopf A J Díaz-del-Río V González F J Somoza L | 2012 | Sedimentary Geology2012，，： | 1 |
| 18 | Free volumesize dependence on temperature and average molecular-weight in poly(^4ethylene oxide) determined by positron annihilation lifetime spectroscopy 显示文摘 | Porto A O Goulart Silva G Magalhes W F | 1999 | Journal of Polymer Science Part B : Polymer Physics1999，37，： | 1 |
| 19 | Thermoregulatory efficiency is increased after heat acclimation in tropical natives 显示文摘 | MAGALHES F C PASSOS R L FONSECA M A | 2010 | J Physiol Anthropol2010，29，1： | 1 |
| 20 | Development of a standard set of microsatellite reference alleles for identification of grape cultivars显示文摘 | THIS P JUNG A BOCCACCI P BORREGO J BOTTA R COSTAN-TINI L CRESPAN M DANGL G S EISENHELDC FERREIRAMONTEIRO F GRANDO S IB(A)(N)EZ J LACOMBE T LAUCOU V MAGALH(A)ES R MEREDITH C P MILANI N PETERLUNGER E REGNER F ZULINI L MAUL E | 2004 | Theor Appl Genet2004，109，： | 1 |
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