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1Optoelectronic devices based on two-dimensional transition metal dichalcogenides显示文摘在过去几年里,二维(2D ) 转变金属 dichalcogenide (TMDC ) 材料吸引了研究社区的增加的注意由于他们的唯一的电子、光的性质,从当放大材料从时,联合到 indirect-to-direct bandgap 转变的山谷纺纱对单层多层。这些性质在通讯,计算,和保健的宽广领域里用重要应用正在恳求电子的小说和 optoelectronic 设备的发展。当材料厚度减少从时, TMDC 家庭的特色之一是发生的 indirect-to-direct bandgap 转变对单层多层,它为许多 photonic 应用是有利的。TMDC 也为与对他们也没有格子失配问题的层厚度的原子水平的控制构造大量 heterostructures 表明了崭新的灵活性和通用性。作为结果,在有另外的 2D 材料的联合的分层的 TMDC 为在宽广操作上认识到新奇高效的 optoelectronic 设备有潜力光谱范围。在这篇文章,我们在 2D TMDC 和 optoelectronic 设备研究的合成考察最近的进步。我们也讨论面对 2D 材料的家庭的可伸缩的应用的挑战并且在这些材料为 nanophotonics 技术的未来代提供的机会上提供我们的观点。He Tian Matthew L. Chin Sina Najmaei Qiushi Guo Fengnian Xia Hart Wang Madan Dubey 2016Nano Research2016,9,6:22
2快速眼动睡眠产生的神经机制:蓝斑核神经元停止发放是一个必要的条件(英文)显示文摘两种类型的神经元参与了快速眼动(rapideyemovement,REM)睡眠的调节:快速眼动-发放(REM-ON)神经元和快速眼动-沉寂神经元(REM-OFF)。快速眼动-沉寂神经元属去甲肾上腺素能神经元,正如名字表示的那样——在快速眼动睡眠期间停止发放。已有研究表明,这些神经元放电活动的停止是导致快速眼动睡眠的前提条件,γ-氨基丁酸(γ-aminobutyricacid,GABA)可使它们停止发放。如果这些神经元不停止发放,脑中的去甲肾上腺素水平将升高,不出现快速眼动睡眠。剥夺快速眼动睡眠所引起的去甲肾上腺素增加,至少是快速眼动睡眠丧失引起Na+-K+ATP酶活性增加的原因,而这可能是导致快速眼动睡眠剥夺所引发的各种效应的主要因素。Dinesh Pal Vibha Madan Birendra Nath Mallick 2005生理学报2005,57,4:8
3Non-alcoholic fatty liver disease may not be a severe disease at presentation among Asian Indians显示文摘瞄准:与非含酒精的脂肝疾病(NAFLD ) 评估病人的临床、生物化学的侧面并且在表示估计他们的组织学的严厉。方法:介绍给所有印度的肝诊所的连续病人与提起的 transaminases 医学科学(AIIMS ) 开创到乘正常的上面的限制的至少 1.5,并且组织学地证实的非酒精的脂肝疾病被包括。或谁有重要白酒吸入或另外的肝疾病的积极标记的病人正在服知道生产脂肝的药被排除。这个组的临床、生物化学、组织学的侧面被学习。结果:有 NAFLD 的 51 个病人形成了学习人口。他们的中部的年龄和 BMI 是 34 (17-58 ) 年并且 26.7 (21.3-32.5 ) kg/m (2 ) 分别地并且(90.1%) 46 是男性。病人的多数有温和发炎,也分级 1 [32 (63%)] 或等级 2 [16 (31%)] 并且仅仅 3 (6%) 病人们有严重(等级 3 ) 发炎。23 (45%) , 19 (37%) , 8 (16%) 并且 1 (2%) 病人有 0, 1, 2 和 3 纤维变性分别地在索引活体检视和没有上有的舞台肝硬化。在 univariate 分析上,甘油三酸酯铺平超过 150 mg %( 或 = 7.1;95% CI:1.6-31.5, P = 0.002 ) 并且著名计算机生产厂商 / 中高音 ratio>1 (或 = 14.3;95% CI:1.4-678.5, P = 0.008 ) 与发炎的高等级被联系,任何一个都没与先进纤维变性被联系。在上多变量逻辑回归分析, hypertriglyceridemia >150 mg% 是独立地与发炎的高等级的存在联系的唯一的因素(或 = 1.6;95% CI:1.3-22.7, P = 0.02 ) ,当任何一个都没与先进纤维变性被联系时。甘油三酸酯层次与煽动性的等级断然相关(r = 0.412;P = 0.003 ) 。结论:在诺思印第安人病人的 NAFLD 是年轻超重男性,其中大多数是抵抗的胰岛素的疾病,他们趋于在表示有温和组织学的疾病。Kaushal Madan Yogesh Batra S Datta Gupta Bal Chander K D Anand Rajan M S Tewatia S K Panda S K Acharya 2006World Journal of Gastroenterology2006,12,21:7
4LOCAL SCOUR AROUND BRIDGE ABUTMENTS显示文摘This paper summarizes the design equations for local scour depth around bridge abutments as proposed by different investigators, and also the different factors, affecting the scour depth. Methods for the estimation of local scour depth based on dimensional analysis are also presented. The design methods based on empirical relations such as flow depth, flow intensity, sediment characteristics, abutments shape and size, alignment, and approach channel geometry are also discussed. Since clear-water scour is the maximum scour depth, the equation for clear-water scour is recommended for the computation of local scour depth around bridge abutments for uniformly and non- uniformly graded sediments.Er. Shri Ram CHAURASIA1 and Pande B.B. LAL2 1 Assistant Professor, Civil Engineering Department, Madan Mohan Malaviya Engineering College, Gorakhpur-273 010 (U.P.) India, 2 Dr., Principal, Mada 2002International Journal of Sediment Research2002,17,1:5
5Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the study of the liver (APASL)显示文摘Shiv Kumar Sarin Ashish Kumar John A. Almeida Yogesh Kumar Chawla Sheung Tat Fan Hitendra Garg H. Janaka Silva Saeed Sadiq Hamid Rajiv Jalan Piyawat Komolmit George K. Lau Qing Liu Kaushal Madan Rosmawati Mohamed Qin Ning Salimur Rahman Archana Rastogi St 2009Hepatology International2009,,1:4
6隧道施工的分析方法显示文摘在任何比较重要的施工方案着手以前,基于可利用的现场资料和调查报告作出的各项设计均已完成。虽然标明有不同种类岩石的岩石支护细部的设计图纸已发给结构工程师,在实际施工中根据它来设置支护,但在隧道工程和洞库构筑物中仍有失误发生。在施工能按要求的速度继续进行以前,为了稳固影响施工的那部份岩体,宝贵的时间被浪费掉了,在本文中作者力图对设计图纸之外常会出现的问题提出分析解答。M M Madan 刘乃武 1992地下空间1992,12,2:4
7Lower gastrointestinal bleeding: Association with Sevelamer use显示文摘Stercoral ulceration results from impaction of hard fecal mass on the colonic wall and is a relatively unknown cause of lower gastrointestinal bleeding. In this report, we describe a case of lower gastrointestinal bleeding due to stercoral ulceration resulting from Sevelamer, a drug which is commonly associated with constipation.Pankaj Madan Suverta Bhayana Prakash Chandra John I Hughes 2008World Journal of Gastroenterology2008,14,16:3
8Socio-economic and Environmental Implications of the Hydroelectric Projects in Uttarakhand Himalaya, India显示文摘This paper deals with detailed analysis of the fiasco created by the Tehri High Dam in Uttarakhand, India, particularly in terms of resettlement and rehabilitation of the local inhabitants. Aspects pertaining to the environmental issues are also discussed. Currently, the river valleys in Uttarakhand state of India are the targets of increasing hydroelectric projects. Virtually all rivers are being exploited for generating environmental friendly power. Having being learned the hard lesson from Tehri Dam, it has been decided to opt for such schemes in which comparatively little submergence and tempering with the fragile eco-systems is involved.However, our observations suggest that even in such schemes if due care is not taken they may turn out to be a failure.Naresh Rana S. P. Sati Y.P. Sundriyal Madan Mohan Doval Navin Juyal 2007Journal of Mountain Science2007,4,4:3
9Determination of flavonoids,polyphenols and antioxidant activity of Tephrosia purpurea:a seasonal study显示文摘OBJECTIVE:Tephrosia purpurea(Linn.) Pers.is widely used in traditional medicine to treat liver disorders,febrile attacks,enlargement and obstruction of liver,spleen,and kidney.In the present study,investigations were carried out to determine the seasonal impact on the content of flavonoid glycosides and on antioxidant activities so as to identify the optimal time of harvesting.METHODS:The plant materials were collected in different seasons during 2013-2014.Air-dried,powdered plant materials were extracted with 95%ethanol and ethanokwater(1:1) by ultrasound-assisted extraction process.Their chemical composition in terms of total polyphenol and flavonoid contents(TPCs and TFCs) was determined using modified colorimetric Folin-Ciocalteu method and aluminum chloride colorimetric assay respectively.To determine the in vitro antioxidant activity,diphenyl-picryl hydrazyl(DPPH) radical-scavenging assay and total antioxidant capacity by phosphomolybdate antioxidant assay were carried out.High-performance liquid chromatography(HPLC)/photo-diode array(PDA) analysis was used to quantify the flavonoid glycosides in the samples collected in different seasons.Correlation studies were also carried out between antioxidant activities and TPCs.RESULTS:The highest TPC and TFC were found to be in the 95%ethanolic extract of the August sample and the lowest in the 50%hydro-alcoholic extract of the plant sample collected in winter season.It was observed that in both the assays used to determine the antioxidant activity,the 95%ethanolic extracts in all the seasons showed a higher activity than their respective 50%hydroalcoholic extracts with an increase in activity as we go from cold to hot to rainy seasons.Based on correlation analysis,DPPH radical-scavenging activities as well as the spectrophotometrically measured phosphomolybdenum complex were also strongly correlated with TPC of the extracts.The most abundant flavonoid glycoside was quercetin-3-O-rhamnoglucoside in all the seasons.The content of all flavonoids was observed highest in the 95%ethanolic extract of the plant collected in August(TP-3).The 50%hydro-alcoholic extract of the plant collected in December(TP-6) showed the lowest amount of flavonoids and antioxidant activity.CONCLUSION:The findings of this study confirmed that the metabolism and production of flavonoids in T.purpurea are vigorously affected by seasonal factors.Significant differences were observed in the TPC,TFC and flavonoid glycoside composition in the 95%ethanolic as well as 50%hydro-alcoholic extracts of T.purpurea collected in different seasons.Since the 95%ethanolic extract of the August sample(TP-3),which also happens to be its flowering season,exhibited the highest TPC.TFC and antioxidant activities in both DPPH and phosphomolybdate assays as well as contained the highest content of all flavonoids,it could be recommended as the optimal season of harvesting T.purpurea with respect to its pharmaceutically important constituents,i.e.,flavonoids.Madan Mohan Pandey Sayyada Khatoon Subha Rastogi Ajay Kumar Singh Rawat 2016Journal of Integrative Medicine2016,14,6:3
10Estimation and feedback control of air-fuel ratio for gasoline engines显示文摘In 4-stroke internal combustion engines, air-fuel ratio control is a challenging task due to the rapid changes of engine throttle,especially during transient operation. To improve the transient performance, managing the cycle-to-cycle transient behavior of the mass of the air, the fuel and the burnt gas is a key issue due to the imbalance of cyclic combustion process. This paper address the model-based estimation and control problem for cyclic air-fuel ratio of spark-ignition engines. A discrete-time model of air-fuel ratio is proposed, which represents the cycle-to-cycle transient behavior of in-cylinder state variables under the assumptions of cyclic measurability of the total in-cylinder charge mass, combustion efficiency and the residual gas fraction. With the model,a Kalman filter-based air-fuel ratio estimation algorithm is proposed that enable us to perform a feedback control of air-fuel ratio without using lambda sensor. Finally, experimental validation result is demonstrated to show the effectiveness of proposed estimation and control scheme that is conducted on a full-scaled gasoline engine test bench.Madan KUMAR Tielong SHEN 2015Control Theory and Technology2015,13,2:3
11Antioxidant Defense System in Wheat (Triticum aestivum L.) Seedlings under Heat Stress and Revival Conditions显示文摘R. Mahla S. Madan M. K. Rana R. Munjal 2011Journal of Agricultural Science and Technology2011,5,1:2
12Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the study of the liver (APASL)显示文摘Shiv Kumar Sarin Ashish Kumar John A. Almeida Yogesh Kumar Chawla Sheung Tat Fan Hitendra Garg H. Janaka Silva Saeed Sadiq Hamid Rajiv Jalan Piyawat Komolmit George K. Lau Qing Liu Kaushal Madan Rosmawati Mohamed Qin Ning Salimur Rahman Archana Rastogi St 2009Hepatology International2009,,1:2
13Outcome of Posterior Lumbar Interbody Fusion Versus Posterolateral Fusion for Spondylolytic Spondylolisthesis显示文摘S. Madan N. R. Boeree 2002Spine2002,,14:2
14Perspectives on the clinical development of mmunotherapy in prostate cancer显示文摘Lisa M Cordes James L Gulley Ravi A Madan 2018Asian Journal of Andrology2018,20,3:2
15Bone loss from Wnt inhibition mitigated by concurrent alendronate therapy显示文摘Dysregulated Wnt signaling is associated with the pathogenesis of cancers, fibrosis, and vascular diseases. Inhibition of Wnt signaling has shown efficacy in various pre-clinical models of these disorders. One of the key challenges in developing targeted anti-cancer drugs is to balance efficacy with on-target toxicity. Given the crucial role Wnts play in the differentiation of osteoblasts and osteoclasts, acute inhibition of Wnt signaling is likely to affect bone homeostasis. In this study, we evaluated the skeletal effect of small molecule inhibitor of an o-acyl transferase porcupine(PORCN) that prevents Wnt signaling by blocking the secretion of all Wnts. Micro-computed tomography and histomorphometric evaluation revealed that the bones of mice treated with two structurally distinct PORCN inhibitors LGK974 and ETC-1922159(ETC-159) had loss-of-bone volume and density within 4 weeks of exposure. This decreased bone mass was associated with a significant increase in adipocytes within the bone marrow. Notably,simultaneous administration of a clinically approved anti-resorptive, alendronate, a member of the bisphosphonate family,mitigated loss-of-bone mass seen upon ETC-159 treatment by regulating activity of osteoclasts and blocking accumulation of bone marrow adipocytes. Our results support the addition of bone protective agents when treating patients with PORCN inhibitors.Mitigation of bone toxicity can extend the therapeutic utility of Wnt pathway inhibitors.Babita Madan Mitchell J.McDonald Gabrielle E.Foxa Cassandra R.Diegel Bart O.Williams David M.Virshup 2018Bone Research2018,6,2:2
16Usefulness of an abnormal ankle-brachial index to predict presence of coronary artery disease in African-Americans显示文摘Kenneth Ese Otah Atul Madan Eseroghene Otah Oluyemi Badero Luther T. Clark Moro O. Salifu 2004The American Journal of Cardiology2004,,4:2
17Assessment of quadriceps muscle thickness using bedside ultrasonography by nurses and physicians in the intensive care unit:Intra- and inter-operator agreement显示文摘BACKGROUND Data regarding the agreement among multiple operators for measurement of quadriceps muscle thickness by bedside ultrasonography(USG)are sparse.AIM To statistically assess the agreement among 5 operators for measurement of quadriceps muscle thickness on bedside USG.METHODS This was a cross-sectional observational study.The 5 operators of varied experience(comprised of 1 critical care consultant,2 fellows,and 2 nurses)independently measured quadriceps muscle thickness in triplicate for 45 critically ill patients each,using USG.Intra-and interrater agreement rates among the 5 operators were assessed using intraclass correlation coefficient(ICC)and expressed with 95%confidence interval(CI).RESULTS The 5 operators produced a total of 135 readings and 675 observations for ICC calculations to determine the intraoperator and interoperator variations respectively.For intraoperator agreement,the overall ICC(95%CI)was 0.998(0.997,0.999)for operator 1,0.998(0.997,0.999)for operator 2,0.997(0.995,0.999)for operator 3,0.999(0.998,0.999)for operator 4,and 0.998(0.997,0.999)for operator 5.For interoperator agreement,the overall ICC(95%CI)was 0.977(0.965,0.986;P<0.001)for reading 1,0.974(0.960,0.984;P<0.001)for reading 2,and 0.975(0.961,0.985;P<0.001)for reading 3.CONCLUSION USG measurement of quadriceps muscle thickness was not dependent on clinical experience,supporting training for nurses in it.Rohit Kumar Tajamul Hussain Shah Vijay Hadda Pawan Tiwari Saurabh Mittal Karan Madan Maroof Ahmad Khan Anant Mohan 2019World Journal of Critical Care Medicine2019,8,7:2
18Dynamo显示文摘Giuseppe DeCandia Deniz Hastorun Madan Jampani Gunavardhan Kakulapati Avinash Lakshman Alex Pilchin Swaminathan Sivasubramanian Peter Vosshall Werner Vogels 2007ACM SIGOPS Operating Systems Review2007,,6:2
19An M/G/1 queue with second optional service显示文摘Madan K C 2000Queueing Systems Theory and Applications2000,34,:1
20Making sense of the e - supply chain landscape : an implementation framework 显示文摘Somendra Pant Rajesh Sethi Madan Bhandari 2003International Journal of Information Management2003,,23:1
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