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| 1 | 前列腺铥激光摘除术治疗良性前列腺增生患者的性功能结果显示文摘患者继发于良性前列腺增生(B P H) 的下尿路症状(LUTS)的治疗可能影响性功能和射精的质量。新的手术方法治疗良性前列腺增生,对勃起和射精的影响,目前研究甚少。这项研究的目的是评估对继发于前列腺增生的LUTS患者,前列腺铥激光摘除术(ThuLEP)对性功能和逆行射精的影响。我们进行了一项前瞻性研究,收集了连续110例行ThuLEP患者,分析性功能和排尿症状的变化。为了评估勃起、射精变化及排尿症状对生活质量(Qol)的影响,我们使用了五个经验证的问卷:ICIQ-MLUTSsex,MSHQ-EJD,IIFE-5,IPSS,以及Qol调查问卷。患者还经过IPSS和尿流率仪来评估尿流率结果。对患者进行ThuLEP术前和术后3-6个月的评估,而那些有既往腹部手术史的病人被排除在外。患者平均年龄为67.83年。术后排尿症状好转。手术前后的勃起功能没有观察到显著差异。与文献中描述的其他技术相比,患者ThuLEP后保留的射精功能增加了52.7%。 通过对患者问卷调查得分的评估,ThuLEP正面影响排尿症状和的和患者的生活质量。而前列腺增生内镜治疗(如经尿道前列腺电切术),导致大多数患者逆行射精。那些接受ThuLEP治疗的患者保留了射精和勃起功能。 | Luca Carmignani Giorgio Bozzini Alberto Macchi Serena Maruccia Stefano Picozzi Stefano Casellato | 2015 | Asian Journal of Andrology2015，17，5： | 16 |
| 2 | Programmed cell death and natural killer cells in multiple sclerosis: new potential therapeutic targets?显示文摘Multiple sclerosis(MS)is a chronic,severe and complex disease of still uncertain etiopathogenesis,with lesions in the cerebral white matter and spinal cord.The disease is heterogeneous,but is characterized by neuroinflammatory and neurodegenerative processes,usually associated with altered activation of the immune system following presumable stimulation by still unknown autoantigens.Several data confirm | Beatrice Macchi Antonio Mastino | 2016 | Neural Regeneration Research2016，11，5： | 3 |
| 3 | B1a lymphocytes in the rectal mucosa of ulcerative colitis patients显示文摘AIM:To assess B1a cell expression in the rectal mucosa of ulcerative colitis (UC) patients in comparison with healthy controls.METHODS:Rectal mucosa biopsies were collected from 15 UC patients and 17 healthy controls.CD5 + B cells were analysed by three colour flow cytometry from rectal mucosal samples after mechanical disaggregation by Medimachine.Immunohistochemical analysis of B and T lymphocytes was also performed.Correlations between,on the one hand,rectal B1a cell concentrations and,on the other,erythrocyte sedimentation rate and C-reactive protein levels and clinical,endoscopic and histological disease activity indices were evaluated.RESULTS:Rectal B-lymphocyte (CD19 + /CD45 +) rate and concentration were higher in UC patients compared with those in healthy controls (47.85% ± 3.12% vs 26.10% ± 3.40%,P=0.001 and 501 ± 91 cells/mm 2 vs 117 ± 18 cells/mm 2,P < 0.001);Rectal B1a cell density (CD5 + CD19 +) was higher in UC patients than in healthy controls (85 ± 15 cells/mm 2 vs 31 ± 6.7 cells/mm 2,P=0.009).Rectal B1a cell (CD5/CD19 +) rate correlated inversely with endoscopic classification (Rs=-0.637,P < 0.05).CONCLUSION:B1a lymphocytes seem to be involved in the pathogenesis of UC,however,the role they play in its early phases and in disease activity,have yet to be defined. | Lino Polese Riccardo Boetto Giuseppe De Franchis Imerio Angriman Andrea Porzionato Lorenzo Norberto Giacomo Carlo Sturniolo Veronica Macchi Raffaele De Caro Stefano Merigliano | 2012 | World Journal of Gastroenterology2012，18，2： | 2 |
| 4 | Direct laser metal sintering as a new approach to fabrication of an isoelastic functionally graded material for manufacture of porous titanium dental implants显示文摘 | T. Traini C. Mangano R.L. Sammons F. Mangano A. Macchi A. Piattelli | 2008 | Dental Materials2008，，11： | 2 |
| 5 | Adaptive recovery of a chirped sinusoid in noise, Part 2: Performance of the LMS algnrithm显示文摘 | Bershad N J Macchi O M | 1991 | IEEE Trans Acoustic Signal Processing1991，39，3： | 1 |
| 6 | Changes in limestone sorbent morphology during CaO-CaCO3 looping at pilot scale显示文摘 | Hughes R W Macchi A Lu D Y | 2009 | Chemical Engineering & Technology2009，32，3： | 1 |
| 7 | Main accessory sulcus of the liver显示文摘 | Macchi V Porzionato A Parenti A | 2005 | ClinAnat2005，18，1： | 1 |
| 8 | Epithelial cell adhesion molecule expression(CD326)in cancer:a short review显示文摘 | Patriarca C Macchi RM Marschner AK | 2012 | Cancer Treat Rev2012，38，1： | 1 |
| 9 | Resistance in vitro to low-dose aspirin is associated with platelet PIA1 (GP Ⅲ a)polymorphism but not with C807T( GP Ⅰ a/Ⅱ a) and CsT Kozak (GP Ibalpha) polymorphisms显示文摘 | Macchi L Christiaens L Brabant S | 2003 | J Am Coll Cardiol2003，42，： | 1 |
| 10 | Ciliary neurotrophicfactor controls progenitor migration during remyelination in theadult rodent brain显示文摘 | Vernerey J Macchi M Magalon K | 2013 | J Neurosci2013，33，7： | 1 |
| 11 | Carbonylation of nitrobenzene catalysed by palladium and heteropolyanions; a mechanistic approach显示文摘 | Ragaini F Macchi M Cenini S | 1997 | J Mol Catal A:Chemical1997，127，123： | 1 |
| 12 | Convergence analysis of self adaptive equalizers显示文摘 | Macchi O Eweda E | | 0，，02： | 1 |
| 13 | Recurrent acute rhinosinusitis:a single blind clinical study of N-acetylcysteine vs ambroxol associated to corticosteroid therapy显示文摘 | Macchi A Terranova P Castelnuovo P | | 0，，01： | 1 |
| 14 | Platelet activation in thrombotic disorders显示文摘 | Bihour C Macchi L | 1993 | New Rev Fr Hematol1993，35，1： | 1 |
| 15 | Platelet activa-tion in thrombotic disorders显示文摘 | Nurden AT Bihour C Macchi L | 1993 | New Rev Fr Hematol1993，35，1： | 1 |
| 16 | High sensitivityC-reactive protein predicts the development of new carotidar-tery plaques in older persons 显示文摘 | Molino-Lova R Macchi C Gori AM | 2010 | Nutr Metab CardiovascDis2010，21，10： | 1 |
| 17 | CO2 laser irradiation of GeO2 pla- nar waveguide fabricated by rf-sputtering 显示文摘 | Chiasera A Macchi C Mariazzi S | 2013 | Opt Mater Express2013，3，9： | 1 |
| 18 | Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID) 显示文摘 | Macchi P Villa A Giliani S | 1995 | Nature1995，377，6544： | 1 |
| 19 | Resistance in vitro to low-dose aspirin is associated with platelet P1A1 (GP Ⅲ a)polymorphism but not with C807T(GP Ⅰ a/Ⅱ a)and C-5T Kozak(GP lbalpha)polymorphisms 显示文摘 | Macchi L Christiaens L Brabant S | 2003 | J A m Coil C ardiol2003，42，6： | 1 |
| 20 | Microturbine and trigeneration:optimization strategies and multiple engine configuration effects显示文摘 | CAMPANARI S BONCOMPAGNI L MACCHI E | 2004 | Transactions of the ASME:Journal of Engineering for Gas Turbine and Power2004，126，： | 1 |
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