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| 1 | Mechanisms of acute cerebral infarctions in patients with middle cerebral artery stenosis: A diffusion‐weighted imaging and microemboli monitoring study显示文摘 | Ka SingWong ShanGao Yu LeungChan TjarkHansberg Wynnie W. M.Lam Dirk W.Droste RichardKay E. BerndRingelstein | 2002 | Ann Neurol2002，，1： | 2 |
| 2 | Major hepatectomy for hepatocellular carcinoma in patients with an unsatisfactory indocyanine green clearance test显示文摘 | C. M.Lam S. T.Fan C. M.Lo J.Wong | 2002 | Br J Surg2002，，8： | 1 |
| 3 | Improved operative and survival outcomes of surgical treatment for hilar cholangiocarcinoma显示文摘 | C. L.Liu S. T.Fan C. M.Lo W. K.Tso C. M.Lam J.Wong | 2006 | Br J Surg2006，，12： | 1 |
| 4 | Efficacy and safety of radiofrequency ablation for perivascular hepatocellular carcinoma without hepatic inflow occlusion显示文摘 | K. K.Ng R. T.Poon C. M.Lam J.Yuen W. K.Tso S. T.Fan | 2006 | Br J Surg2006，，4： | 1 |
| 5 | Central Obesity and Elevated Liver Enzymes显示文摘 | Gregory M.Lam SohrabMobarhan | 2008 | Nutrition Reviews2008，，10： | 1 |
| 6 | Validation of POSSUM scoring systems for audit of major hepatectomy显示文摘 | C.‐M.Lam S.‐T.Fan A. W.‐C.Yuen W.‐L.Law K.Poon | 2004 | Br J Surg2004，，4： | 1 |
| 7 | 阿片类物质对猴免疫缺陷病毒感染的CEM×174细胞内p53合成的调节作用(英文)显示文摘已经证明阿片类物质如吗啡能够刺激猴免疫缺陷病毒 ( SIV)的复制 ,并最终加速细胞死亡 ,但是其机理却研究很少 .为探讨吗啡和甲硫氨酸脑啡肽对细胞内 p53合成的作用 ,用 SIV感染CEM× 1 74细胞 ,同时分析 SIV感染时病理过程的机理 .在 CEM× 1 74细胞感染 SIV后不同时间 ,p53含量逐渐增加 ,但 1 0 -7mol/L的吗啡仅在起始阶段对其有促进作用 .在 SIV感染组加入吗啡或甲硫氨酸脑啡肽进行时间曲线实验时 ,p53含量较低 .加入 1 0 -8~ 1 0 -6mol/L吗啡 8h,正常细胞 p53含量仅有轻微改变 .但在 SIV感染情况下 ,则呈现剂量依赖性的大量增加 .相反 ,1 0 -8- 1 0 -6mol/L甲硫氨酸脑啡肽在 8h时能增加正常细胞 p53合成达 60 % .在 SIV感染时 ,SIV本身能够促进 p53的含量 .尽管各组 p53仍然高于对照组 ,但甲硫氨酸脑啡肽对其不再起作用 .结果提示甲硫氨酸脑啡肽对正常细胞 p53含量有明显影响 ,而吗啡 8h增加 SIV感染细胞的 p53含量可能是其加速爱滋病病理过程的机理之一 . | 李刚 Kanneth M.LAM | 2000 | 中国生物化学与分子生物学报2000，16，2： | 1 |
| 8 | Mechanisms of acute cerebral infarctions in patients with middle cerebral artery stenosis: A diffusion‐weighted imaging and microemboli monitoring study显示文摘 | Ka SingWong ShanGao Yu LeungChan TjarkHansberg Wynnie W. M.Lam Dirk W.Droste RichardKay E. BerndRingelstein | 2002 | Ann Neurol2002，，1： | 1 |
| 9 | Validation and reproducibility of the Heidelberg Edge Perimeter in the detection of glaucomatous visual field defects显示文摘AIM: To validate the ability of the Heidelberg Edge Perimeter(HEP) in detecting glaucomatous visual field(VF) defects compared to the Octopus Visual Field(OVF) Analyzer and to determine the test-retest repeatability of both modalities.METHODS: This prospective, cross-sectional study was conducted at Wills Eye Hospital, Philadelphia, PA. Glaucoma subjects and unaffected controls underwent VF testing using HEP standard automated perimetry(SAP) Ⅲ 30-2 Adaptive Staircase Thresholding Algorithm(ASTA) FAST protocol and OVF G-TOP white-on-white strategy. Testing order was randomized. Pearson's correlation coefficient was calculated for both mean deviation(MD) and pattern standard deviation/square root of loss of variance(PSD/s LV). Receiver operating characteristic(ROC) curves were used to determine the diagnostic abilities of both modalities. Glaucoma subjects returned for repeat testing and intraclass correlation coefficients(ICCs) were calculated to assess test-retest repeatability. RESULTS: Seventy-nine subjects with glaucoma and 36 unaffected controls were enrolled. HEP and OVF were significantly correlated for both MD(r=-0.84; P<0.01) and PSD/s LV(r=0.79; P<0.01). Areas under the ROC curves(AUCs) were also comparable between HEP and OVF for both MD(0.74 and 0.79, respectively; P=0.26) and PSD/sL V(0.74 and 0.82; P=0.08). ICC was high for both HEP (0.96 for MD, 0.95 for PSD/s LV) and OVF(0.82 and 0.88, respectively). Mean test duration(min) was significantly shorter for OVF(2.63) compared to HEP(5.15; P<0.01). CONCLUSION: HEP and OVF show strong correlation for both MD and PSD/s LV, and have similar validity for detecting glaucoma. The test-retest repeatability is high for both HEP and OVF, however the average testing duration of HEP is significantly longer than that of OVF. | Qi N.Cui Priyanka Gogt Jonathan M.Lam Safa Siraj Lisa A.Hark Jonathan S.Myers L.Jay Katz Michael Waisbourd | 2019 | International Journal of Ophthalmology(English edition)2019，12，4： | 0 |
| 10 | Theoretical assessment of the impact of environmental contamination on the dynamical transmission of polio显示文摘A mathematical model for the dynamical transmission of polio is considered,with the aim of investigating the impact of environment contamination.The model captures two infection pathways through both direct human-to-human transmission and indirect human-to-environment-to-human transmission by incorporating the environment as a transition and/or reservoir of viruses.We derive the basic reproduction number R0^env We show that the disease free equilibrium is globally asymptotically stable(GAS)if R0^env<1,while if R0^env>1,there exists a unique endemic equilibrium which is locally asymptotically stable(LAS).Similar results hold for environmental contamination free sub-model(without the incorporation of the indirect transmission).At the endemic level,we show that the number of infected individuals for the model with the environ mental-related contagion is greater than the corresponding number for the environmental contamination free sub-model.In conjunction with the inequality R0 | C.Balde M.Lam A.Bah S.Bowong J.J.Tewa | 2019 | International Journal of Biomathematics2019，12，2： | 0 |
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