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| 1 | Current hepatitis B virus infection situation in Indonesia and its genetic diversity显示文摘Indonesia has a moderate to high endemicity of hepatitis B virus(HBV) infection. The risk for chronic HBV infection is highest among those infected during infancy. Since 1997, hepatitis B(Hep B) vaccination of newborns has been fully integrated into the National Immunization Program. Al though HBV infection has been reduced by the universal newborn Hep B immunization program, it continues to occur in Indonesia. The low birth dose coverage and the presence of vaccine escape mutants might contribute to this endemicity among children. Although limited information is available for an analysis of occult HBV infection(OBI), several variations and substitutions in the pre-S/S region have been detected in Indonesian HBV strains. Additionally, persistent infection and disease progression of chronic hepatitis B are related to not only viral factors but also the host genome. Indonesia is one of the most ethnically heterogeneous nations, with Javanese and Sundanese as the two highest ethnic groups. This multi-ethnicity makes genomic research in Indonesia difficult. In this article, we focused on and reviewed the following aspects: the current hepatitis B immunization program and its efficacy, OBI, HBV infection among high-risk patients, such as hemodialysis patients, and research regarding the host genome in Indonesia. | Maria Inge Lusida Juniastuti Yoshihiko Yano | 2016 | World Journal of Gastroenterology2016，22，32： | 6 |
| 2 | Stem cell therapy and diabetic erectile dysfunction:A critical review显示文摘Erectile dysfunction(ED)has been identified as one of the most frequent chronic complications of diabetes mellitus(DM).The prevalence of ED is estimated to be about 67.4%in all DM cases worldwide.The pathophysiological process leading to ED involves endothelial,neurological,hormonal,and psychological factors.In DM,endothelial and neurological factors play a crucial role.Damages in the blood vessels and erectile tissue due to insulin resistance are the hallmark of ED in DM.The current treatments for ED include phosphodiesterase-5 inhibitors and penile prosthesis surgery.However,these treatments are limited in terms of just relieving the symptoms,but not resolving the cause of the problem.The use of stem cells for treating ED is currently being studied mostly in experimental animals.The stem cells used are derived from adipose tissue,bone,or human urine.Most of the studies observed an improvement in erectile quality in the experimental animals as well as an improvement in erectile tissue.However,research on stem cell therapy for ED in humans remains to be limited.Nevertheless,significant findings from studies using animal models indicate a potential use of stem cells in the treatment of ED. | Cennikon Pakpahan Raditya Ibrahim William William Zakiyatul Faizah Juniastuti Juniastuti Maria I Lusida Delvac Oceandy | 2021 | World Journal of Stem Cells2021，13，10： | 6 |
| 3 | Viral hepatitis and human immunodeficiency virus coinfections in Asia显示文摘Hepatitis B virus(HBV), hepatitis C virus(HCV),and human immunodeficiency virus(HIV) affect many people in Asian countries, although there are geographic differences. Both HBV and HIV(HBV/HIV) and HCV/HIV co-infections are highly prevalent in Asia. Hetero- and homosexual, injection drug use, and geographic area are strong predictors of HBV, HCV, and HIV serostatus. In HBV endemic regions, the prevalence and genotype distribution of HBV/HIV coinfection is almost comparable with that in the general population. In Japan, where HBV has low endemicity, the prevalence of HBV/HIV co-infection is approximately 10-fold higher than that in the general population, and HBV Ae is the most common subgenotype among HIV infected individuals. Highly active antiretroviral therapy(HAART) is an effective treatment for HIV/Acquired Immune Deficiency Syndrome. Lamivudine, a component of HAART, is an effective treatment for HBV, HIV, and HBV/HIV co-infection; however, cost, emerging drug resistance, antiretroviral-associated liver toxicity and liver-related morbidity due to HCV progression are particular concerns. HCV/HIV co-infection may accelerate the clinical progression of both HCV and HIV. The high prevalence of HBV/HIV and HCV/HIV co-infections in Asia underscores the need to improve prevention and control measures, as fewer evidencebased prevention strategies are available(compared with Western countries). In this review, the most recent publications on the prevalence of HBV/HIV and HCV/HIV co-infections and related issues, such as therapy and problems in Asia, are updated and summarized. | Takako Utsumi Maria I Lusida | 2015 | World Journal of Virology2015，4，2： | 2 |
| 4 | Hepatitis B and C virus infection among hemodialysis patients in yogyakarta, Indonesia: Prevalence and molecular evidence for nosocomial transmission显示文摘 | Hanggoro Tri Rinonce Yoshihiko Yano Takako Utsumi Didik Setyo Heriyanto Nungki Anggorowati Dewiyani Indah Widasari Maria Inge Lusida Soetjipto Heru Prasanto Hak Hotta Yoshitake Hayashi | 2013 | J. Med. Virol2013，，8： | 1 |
| 5 | Novel subgenotype of hepatitis B virus genotypes C and D in Papua,Indonesia显示文摘 | Lusida MI Nugrahaputra VE Handajani R | 2008 | J Clin Microbiol2008，46，7： | 1 |
| 6 | Novel subgenotypes of hepatitis B virus genotypes C and D in Papua,Indonesia 显示文摘 | Lusida MI Nugrahaputra VE Soetjipto | 2008 | J Clin Mierobiol2008，46，7： | 1 |
| 7 | Serologic and molecular characteristics of hepatitis B virus among school children in East Java, Indonesia显示文摘 | Utsumi T Yano Y Lusida MI | 2010 | Am J Trop Med Hyg2010，83，1： | 1 |
| 8 | Novel sub- genotypes of hepatitis B virus genoypes C and D in Papua, Indonesia显示文摘 | Lusida MI Nugrahaputra VE Soetjipto | 2008 | J Clin Mierobiol2008，46，7： | 1 |
| 9 | Novel subgenotypes of hepatitis B virus genotypes C and D in Patina,Indonesia显示文摘 | Lusida M1 Nugrahaputra VE Handajani R | | 0，，07： | 1 |
| 10 | Novel subgenotypes of hepatitis B virus genotypes C and D in Papua, Indonesia 显示文摘 | Lusida MI Nugrahaputra VE Soetjipto | 2008 | J Clin Microbiol2008，46，7： | 1 |
| 11 | Novel subgenot - ypes of hepatitis B virus genotypes C and D in Papua, Indonesia 显示文摘 | Lusida MI Nugrahaputra VE Soetjipto | 2008 | J Clin Mi- crobio12008，46，7： | 1 |
| 12 | Complete genome se-quence and phylogenetic relatedness of hepatitis B virus isolates in papua, indonesia显示文摘 | UTSUMI T LUSIDA M I AMIN M | 2009 | J Clin Mierobio12009，47，6： | 1 |
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