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18篇 您的检索式:作者名="Lukyanova"
    题名 作者 年代 出处 被引量
1Vascular endothelial growth factor exression in uterine cervical cancer:correlation with clinicopathologic characteristics and survival显示文摘Goncharuk IV Vorobjova LI Lukyanova NY 0,,03:1
2Energeticneutralat-omimagingatMercury显示文摘LukyanovA BarabashS HolmstromM 2004AdvancesinSpaceResearch2004,33,11:1
3Postoperative autovae- cinotherapy for patients with gastric cancer and expression of some proteins in tumor tissue显示文摘Bazas VM Lukyanova NY Lisovenko GS 2009Exp Onco12009,31,3:1
4Vascular endothelial growth factor exression in uterine cervical cancer:correlation with clinicopathologic characteristics and survival显示文摘Goncharuk IV Vorobjova LI Lukyanova NY 2009Exp Oncol2009,31,3:1
5Micelles from polyethylene glycol/ phosphatidylethanolamine conjugates for tumor drug delivery显示文摘LUKYANOVA N GAO Z G TOCHILIN V P 0,,1:1
6Expres sion of drug resistance proteins in triple-receptor-negative lumors as the basis of individualized therapy of the breast cancer patients 显示文摘Chekhun V F Zhylchuk V E Lukyanova N Y 2009ExpOncol2009,31,12:1
7Cadmium bioaccumulation in organs of scallop Mizuhopecten yessoensis显示文摘Evtushenko Z S Lukyanova O N Belcheva N N 1990Mar Biol1990,104,2:1
8Anthropometric,environmental,and dietary predictors of elevated blood cadmium levels in ukrainian children:Ukraine elspac group显示文摘Friedman LS Lukyanova EM Kundiev YI 0,,01:1
9Vascular endothelial growth factor exression in uterine cervical cancer:corelation with clinicopathologic characteristics and survival显示文摘Goneharuk IV Vorobjova LI Lukyanova NY 2009Exp Oncol2009,31,3:1
10Reversion after ageing in an Mg-Y-Gd-Zr alloy显示文摘LUKYANOVA E A ROKHLIN L L TABACHKOVA Y N DOBATKINA T V NIKITINA N I 2015J Alloys Compd2015,635,:1
11The standard enthalpy of formation of silver pivalate显示文摘LUKYANOVA V A PAPINA T S DIDENKO K V 2008Journal of Thermal Analysis and Calorimetry2008,92,74:1
12Characteristics of homocysteine-induced multidrug resistance of human MCF-7 breast cancer cells and human A2780 ovarian cancer cells 显示文摘Lukyanova NY 2010Exp Oncol2010,32,1:1
13Molecular profileand cell cycle in MCF 7 cells resistant to cisplatin and doxorubicin 显示文摘LUKYANOVA N Y RUSETSKYA N V TREGUBO- VA N A 2009Exp On- col2009,31,:1
14A new role for PGRP-S(Tag7)in immune defense:lymphocyte migration is induced by a chemoattractant complex of Tag7 with Mts1显示文摘DUKHANINA E A LUKYANOVA T I ROMANOVA E A 2015Cell Cycle2015,14,22:1
15Comparative analysis of secretion of S100A4 metastatic marker by immune and tumor cells显示文摘Dukhanina EA Lukyanova TI Romanova EA 2008Bull Exp Biol Med2008,145,1:1
16Relation between cell-to-cell adhesion and angiogenesis and clinico-morphological prognostic factors in patients with gastric cancer显示文摘Myasoedov DV Bazas VM Lukyanova NY 2008Exp Oncol2008,30,3:1
17Vascular endothelial growth factor exression in uterine cervical cancer:correlation with clinicopathologic characteristics and survival显示文摘Goncharuk IV Vorobjova LI Lukyanova NY 2009Exp Oncol2009,31,3:1
18Boceprevir plus peginterferon/ribavirin for treatment ofchronic hepatitis C in Russia显示文摘AIM: to evaluate addition of boceprevir to peginterferon/ribavirin(PR) in Russian patients with chronic hepatitis C virus(HCV).METHODS: treatment-naive(t N) and treatmentexperienced(t E) patients(who had failed prior treatment with PR for ≥ 12 wk) with chronic HCV genotype 1 infection were enrolled in this placebocontrolled, double-blind study. All patients initially received PR for 4 wk. Patients randomized to control treatment then received PR for an additional 44 wk. t N patients randomized to triple therapy received boceprevir(800 mg three times daily) plus PR for 24 wk and then further therapy according to treatment week 8(t W8) HCV RNA levels. t E patients received boceprevir plus PR for 32 wk and then further therapy according to t W8 HCV RNA levels. treatment was discontinued for t N patients with detectable HCV RNA at t W24 and t E patients with detectable HCV RNA at t W12 because of futility. the primary efficacy end point was sustained virologic response(SVR) defined as undetectable HCV RNA 24 wk after completing all study therapy.RESULTS: SVR was 74.8% in the boceprevir plus PR arm compared with 46.2% in the control arm, with a stratification-adjusted treatment difference of 29.2%(95%CI: 16.4-41.5; P < 0.0001). Rates of SVR were higher in the boceprevir arm in both t N and t E patient groups(t N 78.4% vs 56.3%; t E 69.4% vs 30.0%). Within t E patients, the rates of SVR were higher with boceprevir plus PR compared with PR, regardless of treatment failure type(null responder, partial responder, and relapser). Most patients receiving boceprevir plus PR in both t N(86%) and t E(71%) populations were eligible for reduced treatment duration. Anemia was increased in patients receiving boceprevir plus PR vs PR alone(47.2% vs 24.4%); there was a corresponding increase in ribavirin dose reduction and erythropoietin use. Among patients receiving boceprevir plus PR, SVR rates were similar in patients with anemia(< 10 g/d L) and those without anemia(71.2% vs 77.4%).CONCLUSION: Regulatory approval has been obtained for boceprevir plus PR in Russian patients with HCV genotype 1 infection based on the results of this study.Vasily Isakov Igor Nikitin Vladimir Chulanov Pavel Ogurtsov Ekaterina Lukyanova Jianmin Long JaniceWahl Frans A Helmond the P08160 Trial Investigators 2016World Journal of Hepatology2016,8,6:0
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