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| 1 | Pantoprazole in severe acid-peptic disease: the effectiveness and safety of 5 years’ continuous treatment显示文摘 | K.D. Bardhan A.E. Bishop J.M. Polak H.M. Romanska A. Rowland M. Thompson P. Morris S. Schaefer-Preuss R. Luehmann B. McCaldin | 2004 | Digestive and Liver Disease2004，，1： | 1 |
| 2 | Extra- cellular amyloid formation and associated pathology in neural grafts显示文摘 | Meyer Luehmann M Stalde M Herzig M C | 2003 | Nat Neurosci2003，6，： | 1 |
| 3 | Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy显示文摘 | Spires TL Meyer- Luehmann M Stern EA | 2005 | J Neurosci2005，25，： | 1 |
| 4 | Comparison study of gold nanohexapods, nanorods, and nanocages for photothermal cancer treatment显示文摘 | Wang Y Black K C Luehmann H | 2013 | ACS Nano2013，7，3： | 1 |
| 5 | Radiolumines- cent gold nanoeages with controlled radioactivity for real-time in vivo imaging显示文摘 | Wang Y Liu Y Luehmann H | 2013 | Nano Letters2013，13，2： | 1 |
| 6 | Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease显示文摘 | Meyer Luehmann M Spires-Jones TL Prada C | 2008 | Nature2008，451，7179： | 1 |
| 7 | How can blogging help teachers realize the goals of reform-based science instruction;A study of nine classroomblogs显示文摘 | Luehmann A L Frink J | 2009 | Journal of Science Education and Technology2009，18，3： | 1 |
| 8 | Comparison Study of Gold Nanohexapods, Nanorods, and Nanocages for Photothermal Cancer Treatmen 显示文摘 | Wang Y C Black K C L Luehmann H | 2013 | A CS Nano2013，7，3： | 1 |
| 9 | of amyloid-beta plaques in a mouse model of Alzheimer's disease 显示文摘 | Meyer Luehmann Rapid appearance M Spires Jones TL and local toxicity Parada C | 2008 | Nature2008，451，7179： | 1 |
| 10 | Technical requirements for rapid high-efficiency therapies显示文摘 | Luehmann D Ilstrup K | 1986 | Artif Organs1986，10，3： | 1 |
| 11 | Ultrasmall,elementary and highly translational nanoparticle X-ray contrast media from amphiphilic iodinated statistical copolymers显示文摘To expand the single-dose duration over which noninvasive clinical and preclinical cancer imaging can be conducted with high sensitivity,and well-defined spatial and temporal resolutions,a facile strategy to prepare ultrasmall nanoparticulate X-ray contrast media(nano-XRCM)as dual-modality imaging agents for positron emission tomography(PET)and computed tomography(CT)has been established.Synthesized from controlled copolymerization of triiodobenzoyl ethyl acrylate and oligo(ethylene oxide)acrylate monomers,the amphiphilic statistical iodocopolymers(ICPs)could directly dissolve in water to afford thermodynamically stable solutions with high aqueous iodine concentrations(>140 mg iodine/mL water)and comparable viscosities to conventional small molecule XRCM.The formation of ultrasmall iodinated nanoparticles with hydrodynamic diameters of ca.10 nm in water was confirmed by dynamic and static light scattering techniques.In a breast cancer mouse model,in vivo biodistribution studies revealed that the64Cu-chelator-functionalized iodinated nano-XRCM exhibited extended blood residency and higher tumor accumulation compared to typical small molecule imaging agents.PET/CT imaging of tumor over 3 days showed good correlation between PET and CT signals,while CT imaging allowed continuous observation of tumor retention even after 10 days post-injection,enabling longitudinal monitoring of tumor retention for imaging or potentially therapeutic effect after a single administration of nano-XRCM. | Lu Su Kellie S.Dalby Hannah Luehmann Sussana A.Elkassih Sangho Cho Xun He Lisa Detering Yen-Nan Lin Nari Kang Dennis A.Moore Richard Laforest Guorong Sun Yongjian Liu Karen L.Wooley | 2023 | Acta Pharmaceutica Sinica B2023，13，4： | 0 |
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