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376篇 您的检索式:作者名="Lu SC"
    题名 作者 年代 出处 被引量
1The modulation of co-stimulatory molecules by circulating exosomes in primary biliary cirrhosis显示文摘Exosomes 是 endocytic 起源的 nanoparticles,由由他们调制 cell-to-cell 通讯的能力的优点正在吸引增加的注意的无数房间人口藏匿了。他们也在许多免疫学的问题正在吸引注意,包括 autoimmunity 和,特别地调整 cytokine 和 chemokine 激活的他们的能力。主要胆汁的肝硬化(PBC ) 被认为一个模型自体免疫疾病,它对胆汁的上皮的房间有高度集中的细胞毒素的回答。我们与 PBC 和 30 健康控制(HC ) 从 29 个病人从血浆孤立 exosomes,并且用一个前 vivo 系统在 mononuclear 房间人口在 co-stimulatory 分子表示和 cytokine 生产上学习了这些 exosomes 的效果。我们也与 HC exosomes 相比在 PBC 识别了 microRNA (miRNA ) 人口。我们此处报导尽管 exosomes 不改变 cytokine 生产,他们显著地确实在介绍抗原的人口上改变 co-stimulatory 分子表示。进一步,我们在 CD14 + 单核白血球上表明了那 CD86 起来调整的表情,而在 CD11c + 上起来调整的 CD40 由从有 PBC 的病人的 exosomes 的树枝状的房间。另外,有在有 PBC 的病人的传播 exosomes 的 miRNA 表示的差别。这些数据基于 co-stimulatory 分子玩的观察有重要重要性在 T 房间激活的规定的一个微分角色。我们的观察显示从 PBC 的异常 exosomes 有选择地在介绍抗原的房间的不同子集导致 co-stimulatory 分子的表示。这些改变可以在自体免疫的肝疾病的致病包含。Takashi Tomiyama Guo-Xiang Yang Ming Zhao Weici Zhang Hajime Tanaka Jing Wang Patrick SC Leung Kazuiclli Okazaki Xiao-Song He Qianjin Lu Ross L Coppel Christopher L Bowlus M Eric Gershwin 2017Cellular & Molecular Immunology2017,14,3:18
2Experimental study of gold distribution in the algae-organic matter-fluid system显示文摘THE previous simulating experiments show that many algae can greatly accumulate goldfrom solution under some conditions. Some other experiments further indicate that organ-ic matter and crude oil can also play an important role in gold geochemistry processes such asleaching, migration, reduction and precipitation. However, these biometallogeneses areXie, SC Yin, HF Wang, HM Zhou, XG Fu, JM Sheng, GY Zhang, HZ Lu, JL 1997Chinese Science Bulletin1997,42,19:3
3Body distribution of camptothecin solid lipid nanoparticles after oral administration 显示文摘Yang SC Zhu JB Lu Y 1999Pharm Res1999,16,5:1
4Burkholderia cepacia bacteremia:a retrospective analysis of 70 episodes显示文摘Lu DC Chang SC Chen YC 0,,12:1
5Role of S-Adenosyl-L-Methionine in Liver Health and Injury显示文摘Mato JM Lu SC 2007Hepatology2007,45,5:1
6Regulation of hepatic glutathione synthesis显示文摘Lu SC 1998Sem Liv Dis1998,18,1:1
7Body distribution in mice of intravenously injected camptothecin solid lipid nanoparticles and targeting effect on brain 显示文摘Yang SC Lu LF Cai Y 1999J Controlled Release1999,59,3:1
8A new classification of the types of sphenoid sinus pneumatization 显示文摘Lu SC Lu GY 1990J Med Coll PLA1990,5,:1
9Role of S-adenosyl-L-methionine in liver health and injury显示文摘MATO JM LU SC 2007Hepatology2007,45,5:1
10S-Adenosylmethionine in Cell Growth,Apoptosis and Liver Cancer显示文摘Lu SC Mato JM 2008J Gastroenterol Hepatol2008,23,1:1
11Current concepts in the pathogenesis of alcoholic liver injury显示文摘Tsukamoto H Lu SC 2001FASEB J2001,15,:1
12Therapeutic efficacy of sequential and simultaneous treatments with interferon-alpha and lamivudine in children with chronic hepatitis B显示文摘Akman SA Okcu SC Halicio?lu O 2007Pediatr Int2007,49,6:1
13Use of electrical stimulation at different current levels to promote recovery after peripheral nerve injury in rats显示文摘Lu MC Tsai CC Chen SC 2009J Trauma2009,65,5:1
14Role of S-adenosyl-L-methionine in liver health and injury显示文摘Mato JM Lu SC 2007Hepatology2007,45,5:1
15Body distribution in mice of intravenously injected camptothecin solid lipid nanoarpticles and targeting effect on brain 显示文摘Yang SC Lu LF Cai Y 1999J Control Release1999,59,3:1
16Lipopolysaceharide increases resistin gene expression in vivo and in vitro显示文摘Lu SC Shieh WY Chen CY 2002FEBS Lett2002,530,13:1
17Hepatic MR imaging using ferumoxides: prospective evaluation with surgical and intraoperative sonographic confirmation in 25 cases 显示文摘 Lu DS Chen SC 2001AJR2001,177,4:1
18Homocysteine : the bad thiol 显示文摘MATO JM LU SC 2005HEPATOLOGY2005,41,:1
19显示文摘Lu SC 1999FASEB1999,13,:1
20Role of S-adenosyl-L-methionine in liver health and injury显示文摘Mato JM Lu SC 2007Hepatology2007,45,5:1
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