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| 1 | 生物医用植入体钛基合金及其表面生物活性氧化层的制备:机遇与挑战显示文摘钛及其合金因其优异的力学性能和良好的生物相容性,长期以来一直被用作植入材料。尽管如此,研究人员和行业仍在积极寻求更好的合金,因为仍有一些迫切的问题需要关注,包括:(1)由于种植体材料与人体骨组织的弹性模量不匹配而导致的应力屏蔽问题;(2)Ti合金长期使用后有害离子的释放问题;(3)钛合金表面生物活性低而导致愈合过程延长。为了解决这些问题,很多研究工作致力于寻找含有更强生物相容性相成分的新一代钛合金,并对其表面进行改性,使其从天然的生物惰性转变为生物活性。本文回顾了最近报道的钛合金制备方面的工作,并基于所做的调查,强调弹性模量和使用无毒金属元素来提高生物相容性的重要性。在钛合金的表面改性方面,大量研究发现在表面生长的纳米氧化层有利于提高钛合金的生物活性,使其在植入后能够快速修复组织。本文全面地综述并重点考察适合用于生物医用植入体新型钛合金的相和成分,并强调制备和表面改性方法。 | Mohamad Rodzi SITI NUR HAZWANI Ling Xin LIM Zainovia LOCKMAN Hussain ZUHAILAWATI | 2022 | Transactions of Nonferrous Metals Society of China2022，32，1： | 5 |
| 2 | Landscape features and weather influence nest survival of a ground-nesting bird of conservation concern,the greater sage-grouse,in humanaltered environments显示文摘Introduction:Ground-nesting birds experience high levels of nest predation.However,birds can make selection decisions related to nest site location and characteristics that may result in physical,visual,and olfactory impediments to predators.Methods:We studied daily survival rate[DSR]of greater sage-grouse(Centrocercus urophasianus)from 2008 to 2010 in an area in Wyoming experiencing large-scale alterations to the landscape.We used generalized linear mixed models to model fixed and random effects,and a correlation within nesting attempts,individual birds,and years.Results:Predation of the nest was the most common source of nest failure(84.7%)followed by direct predation of the female(13.6%).Generally,landscape variables at the nest site(≤30 m)were more influential on DSR of nests than features at larger spatial scales.Percentage of shrub canopy cover at the nest site(15-m scale)and distances to natural gas wells and mesic areas had a positive relationship with DSR of nests,whereas distance to roads had a negative relationship with DSR of nests.When added to the vegetation model,maximum wind speed on the day of nest failure and a 1-day lag in precipitation(i.e.,precipitation the day before failure)improved model fit whereby both variables negatively influenced DSR of nests.Conclusions:Nest site characteristics that reduce visibility(i.e.,shrub canopy cover)have the potential to reduce depredation,whereas anthropogenic(i.e.,distance to wells)and mesic landscape features appear to facilitate depredation.Last,predators may be more efficient at locating nests under certain weather conditions(i.e.,high winds and moisture). | Stephen L Webb Chad V Olson Matthew R Dzialak Seth M Harju Jeffrey B Winstead Dusty Lockman | 2012 | Ecological Processes2012，1，1： | 2 |
| 3 | Influence of electrolyte pH on TiO 2 nanotube formation by Ti anodization显示文摘 | Srimala Sreekantan Zainovia Lockman Roshasnorlyza Hazan Minoo Tasbihi Lee Keat Tong Abdul Rahman Mohamed | 2009 | Journal of Alloys and Compounds2009，，1： | 2 |
| 4 | Photoactivity of anatase–rutile TiO 2 nanotubes formed by anodization method显示文摘 | Srimala Sreekantan Roshasnorlyza Hazan Zainovia Lockman | 2009 | Thin Solid Films2009，，1： | 2 |
| 5 | Nanoparticle surface charges alter blood-brain barrier integrity and permeability显示文摘 | Lockman PR Koziara JM Mumper B J | 2004 | J Drug Target2004，12，910： | 1 |
| 6 | Heterogeneous blood - tumor barrier permeability determines drug efficacy in experimental brain metastases of breast Cancer 显示文摘 | Lockman PR Mittapalli RK Taskar KS | 2010 | Clin Cancer Res2010，16，： | 1 |
| 7 | Design provisions for drying shrinkage and creep of normal-strength concrete显示文摘 | Gardner N J Lockman M J | 2001 | ACI Materials Journal2001，98，2： | 1 |
| 8 | Computed tomography guided management of interfraetional patient variation 显示文摘 | Yan D Lockman D Martinez A | 2005 | Semin Radiat Oncol2005，15，3： | 1 |
| 9 | Computed tomography guided management of interfractional patient variation显示文摘 | Yan D Lockman D Martinez A | 2005 | Semin Radiat Oncol2005，15，3： | 1 |
| 10 | Improvement in dose escalation using the process of adaptive radiotherapy combined with threedimensional conformal or intensity-modulated beams for prostate canc- er显示文摘 | Martinez AA Yan D Lockman D | 2001 | Int J Radiat Oncol Biol Phys2001，50，5： | 1 |
| 11 | The transport of choline显示文摘 | Lockman PR Allen DD | 2002 | Drug Dev Ind Pharm2002，28，7： | 1 |
| 12 | Nanoparticle surface charges alter blood-brain barrier integrity and permeability显示文摘 | Lockman PR Koziara JM Mumper RJ | 2004 | J Drug Targeting2004，12，910： | 1 |
| 13 | Srivastava, metastasis of breast tumor ceils to brain is suppressed by phenethyl isothiocyanate in a novel metastasis model 显示文摘 | Gupta P Adkins C Lockman P | 2013 | PloS One2013，8，67： | 1 |
| 14 | In vivo and in vitro as- sessment of baseline blood-brain barrier parameters in the pres- ence of novel nanoparticles 显示文摘 | Lockman PR Koziara J Roder KE | 2003 | Pharm Res2003，20，5： | 1 |
| 15 | Nanoparticle technology for drug delivery across the blood-brain barrier显示文摘 | Lockman PR Mumper RJ Khan MA | 2002 | Drug Dev Ind Pharm2002，28，： | 1 |
| 16 | Male circumcision:an acceptable strategy for HIV prevention in Botswana显示文摘 | Kebaabetswe P Lockman S Mogwe S | 2003 | Sex Trans- minf2003，79，3： | 1 |
| 17 | Assessment of residual error for online cone-beam CT-guided treatment of prostate cancer patients显示文摘 | Létourneau D Martinez AA Lockman D | | 0，，： | 1 |
| 18 | Treatment-for-prevention: clinical consider- ations Harvard Medical School, Brigham and Women's Hospital, Harvard School of Public Health, Boston, Massachusetts, USA 显示文摘 | Lockman S Sax P | 2012 | CurrOpinHIVAIDS2012，7，2： | 1 |
| 19 | Brain Iron toxici- ty: differential responses of astroeytes, neurons, and endothelial cells显示文摘 | Gaasch JA Lockman PR Geldenhuys WJ | 2007 | Neurochem Res2007，32，7： | 1 |
| 20 | Ab initio study of hydrogen-bonded complexes of small of organic molecules with water显示文摘 | RABLEN P R LOCKMAN J W JORGENSENW L | 1998 | J Phys Chem:A1998，102，： | 1 |
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