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	题名	作者	年代	出处	被引量
1	Antibody detection and sequence analysis of sporadic HEV in Xiamen region显示文摘	Huang RT Li XY Xia XB Yuan XT Liu MX Li DR	1999	World Journal of Gastroenterology1999，5，3：	6
2	Infant cholestasis patient with a novel missense mutation in the AKR1D1 gene successfully treated by early adequate supplementation with chenodeoxycholic acid: A case report and review of the literature显示文摘Steroid 5β-reductase [aldo-keto reductase family 1 member D1(AKR1D1)] is essential for bile acid biosynthesis. Bile acid deficiency caused by genetic defects in AKR1D1 leads to life-threatening neonatal hepatitis and cholestasis. There is still limited experience regarding the treatment of this disease. We describe an infant who presented with hyperbilirubinemia and coagulopathy but normal bile acid and γ-glutamyltransferase. Gene analysis was performed using genomic DNA from peripheral lymphocytes from the patient, his parents, and his elder brother. The patient was compound heterozygous for c.919C>T in exon 8 and exhibited a loss of heterozygosity of the AKR1D1 gene, which led to an amino acid substitution of arginine by cysteine at amino acid position 307(p.R307C). Based on these mutations, the patient was confirmed to have primary 5β-reductase deficiency. Ursodeoxycholic acid(UDCA) treatment did not have any effect on the patient. However, when we changed to chenodeoxycholic acid(CDCA) treatment, his symptoms and laboratory tests gradually improved. It is therefore crucial to supplement with an adequate dose of CDCA early to improve clinical symptoms and to normalize laboratory tests.	Hui-Hui Wang Fei-Qiu Wen Dong-Ling Dai Jian-She Wang Jing Zhao Kenneth DR Setchell Li-Na Shi Shao-Ming Zhou Si-Xi Liu Qing-Hua Yang	2018	World Journal of Gastroenterology2018，24，35：	3
3	Breast cancer metastasis suppressor 1 functions as a corepressor by enhancing histone deacetylase 1-mediated deacetylation of RelA/p65 and promoting apoptosis显示文摘	Liu Y Smith PW Jones DR	2006	Mol Cell Biol2006，26，23：	1
4	Effect of linoleic acid concentration on conjugated linoleic acid production by Butyrivibrio fibrisolvens A38显示文摘	Kim Y J Liu RH Bond DR	2000	Applied and Environmental Microbiology2000，66，12：	1
5	Positional change in blood pressure and 8-year risk of hypertension:the CARDIA Study显示文摘	Thomas RJ Liu K Jacobs DR		0，，08：	1
6	Expression of calciumbinding protein S100A2 in breast lesions显示文摘	Liu D Rudland PS Sibson DR	2000	Br J Cancer2000，83，11：	1
7	Effects of chronic renal failure and growth hormone therapy on the insuline-like growth factors and their binding proteins显示文摘	Powell DR Liu F Baker BK	2000	Pediatr Nephrol2000，14，7：	1
8	Cellular construction of a circadian clock: period determination in the suprachiasmatic nuclei 显示文摘	Liu C Weaver DR Strogatz SH	1997	Cell1997，91，6：	1
9	Diffusion of the interspecies electron carriers H2 and formate in methanogenic ecosystems and its implications in the measurement of Km for H2 or formate uptake 显示文摘	Boone DR Johnson RL Liu Y	1989	Appl Environ Microbiol1989，55，7：	1
10	Practical considerations for large-scale cryopreservation of a tissue engineered human dermal replacement显示文摘	Applegate DR Liu K Mansbridge J	1999	Advances in Heat and Mass Transfer in Biotechnology1999，44，：	1
11	Positional change in blood pressure and 8-year risk of hypertension:The CARDIA Study显示文摘	Thomas RJ Liu K Jacobs DR Jr	2003	Mayo Clin Proc2003，78，8：	1
12	Progress in research into the mechanism of Radix salvise mliltiorrhizae in treatment of acute pancreatitis显示文摘	Zing XP Li ZJ Liu DR	2006	Hepatobiliary Panereat Dis Int2006，5，4：	1
13	Progress in research into the mech- anism of radix salviae mihiorrhizae in treatment of acute pan- creatitis 显示文摘	Zhang XP Li ZJ Liu DR	2006	Hepatobiliary Pancreat Dis Int2006，5，4：	1
14	Compressive deformation of a single microcapsule显示文摘	Liu KK Williams DR Briscoe BJ	1996	Phys Bey1996，54，：	1
15	Breast cancer metastasis suppressor 1 functions as a corepressor by enhancing histone deacetylase 1-mediated deacetylation of RelA/p65 and promoting apoptosis 显示文摘	Liu Y Smith PW Jones DR	2006	Mol Cell Biol2006，26，23：	1
16	Remnant like particles may induce atherosclerosis via accelerating endothelial progenitor cells senescence显示文摘	Pu DR Liu Ling	2007	Med Hypotheses2007，69，2：	1
17	Prevalence and significance of unrecognised lower extremity peripheral arterial disease in general medicine practice显示文摘	McDermott MM Kerwin DR Liu K	2001	J Gen Intern Med2001，16，：	1
18	Metformin inhibits gangli- onic neurotransmission in renal nerves 显示文摘	Petersen JS Liu W Kapusta DR	1997	Hypertension1997，29，5：	1
19	Endemic goitre in central China caused by excessive iodine intake显示文摘	Li M Liu DR Qu CY	1987	Lancet1987，2，8553：	1
20	Preferential Humoral Immune Response in Prostate Cancer to Cellular Proteins p90 and p62 in a Panel of Tumor-Associated Antigens 显示文摘	Shi FD Zhang JY Liu DR	2005	Prostate2005，63，3：	1

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