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| 1 | Current advances in the application of proteomics in apoptosis research显示文摘Apoptosis,or programmed cell death,is a complex,genetically-determined process involved in the development and maintenance of homeostasis in multicellular organisms.Dysregulation of apoptosis has been implicated in a number of diseases,including cancer and autoimmune disease.Thus,the investigation of apoptotic regulation has evoked considerable interest.Many apoptotic proteins have been shown to be post-translationally modulated,such as by protein cleavage,translocation,protein-protein interaction,and various post-translational modifications,which fall precisely within the range of proteomic analysis.Recently,contemporary proteomic technologies have achieved significant advances and have accelerated research in functional and chemical proteomics,which have been applied to the field of apoptosis research and have the potential to be a driving force for the field.This review highlights some of the major achievements in the application of proteomics in apoptosis research and discusses new directions and challenges for the near future. | WANG LiShun & CHEN GuoQiang Department of Pathophysiology,Key Laboratory of Cell Differentiation and Apoptosis of Ministry of Education of China E-Institutes of Shanghai Municipal Education Commission Chemical Biology Division,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China | 2011 | Science China(Life Sciences)2011，54，3： | 5 |
| 2 | Molecular Characterization of Hydrotreated Atmospheric Residue Derived from Arabian Heavy Crude by GC FI/FD TOF MS and APPI FT-ICR MS显示文摘High resolution mass spectrometry in combination with distillation and SARA fractionation provides us an opportunity for in-depth understanding about the hydrotreating process at the molecular level. In this study, the atmospheric residue derived from Arabian heavy crude and its hydrotreated products were initially subjected to distillation and SARA fractionation. The saturates were characterized by GC FI/FD TOF MS. The aromatics and resins were characterized by APPI FT-ICR MS. Compositional changes of different compounds (paraffins, naphthenes, aromatic hydrocarbons, and heteroatomic compounds) contained in different distillates (vacuum gas oil, vacuum residue) were obtained. More detailed knowledge about the hydrotreating process was achieved. | Diao Rui Wang Wei Wang Naixin Liu Zelong Dai Lishun Tian Songbai | 2012 | China Petroleum Processing & Petrochemical Technology2012，14，4： | 4 |
| 3 | MoSe2 nanosheets as a functional host for lithium-sulfur batteries显示文摘Lithium-sulfur batteries(LSBs) hold great potential for large-scale electrochemical energy storage applications. Currently, the shuttle of soluble lithium polysulfide(LiPSs) intermediates with sluggish conversion kinetics and random deposition of Li2S have severely degraded the capacity, rate and cycling performances of LSBs, preventing their practical applications. In this work, ultrathin MoSe2 nanosheets with active edge sites were successfully grown on both internal and external surfaces of hollow carbon spheres with mesoporous walls(MCHS). The resulting MoSe2@MCHS composite acted as a novel functional reservoir for Li PSs with high chemical affinity and effectively mediated their fast redox conversion during charge/discharge as elucidated by experimental observations and first-principles density functional theory(DFT) calculations. The as-fabricated Li-S cells delivered high capacity, superior rate and excellent cyclability. The current work presents new insights on the delicate design and fabrication of novel functional composite electrode materials for rechargeable batteries with emerging applications. | Lishun Meng Yuan Yao Jing Liu Zhao Wang Dong Qian Liuchun Zheng Bao-Lian Su Hong-En Wang | 2020 | Journal of Energy Chemistry2020，29，8： | 4 |
| 4 | Exitence of multiple positive solutions of three point boundary value problem显示文摘 | Ren Lishun Wang Zhiguo | 2006 | Chinese Quarterly Journal of Mathematics2006，39，4： | 1 |
| 5 | Poly(vinylidene fluoride)/polyethersulfone blend membranes: Effects of solvent sort, polyethersulfone and polyvinylpyrrolidone concentration on their properties and morphology 显示文摘 | Lishun Wu Junfen Sun Qingrui Wang | 2006 | Journal of Membrane Science2006，285，： | 1 |
| 6 | Poly(vinyli-dene fluoride)/Polyethersulfone blend memebranes:effects of solvent sort,polyethersulfone and polyvi-nylpyrrolidone concentration on their properties andmorphology显示文摘 | Wu Lishun Sun Junfen Wang Qingrui | 2006 | J Membr Sci2006，285，： | 1 |
| 7 | Snapshot spectral compressive imaging reconstruction using convolution and contextual Transformer显示文摘Spectral compressive imaging(SCI) is able to encode a high-dimensional hyperspectral image into a twodimensional snapshot measurement, and then use algorithms to reconstruct the spatio-spectral data-cube. At present, the main bottleneck of SCI is the reconstruction algorithm, and state-of-the-art(SOTA) reconstruction methods generally face problems of long reconstruction times and/or poor detail recovery. In this paper, we propose a hybrid network module, namely, a convolution and contextual Transformer(CCo T) block, that can simultaneously acquire the inductive bias ability of convolution and the powerful modeling ability of Transformer, which is conducive to improving the quality of reconstruction to restore fine details. We integrate the proposed CCo T block into a physics-driven deep unfolding framework based on the generalized alternating projection(GAP) algorithm, and further propose the GAP-CCo T network. Finally, we apply the GAP-CCo T algorithm to SCI reconstruction. Through experiments on a large amount of synthetic data and real data,our proposed model achieves higher reconstruction quality(>2 d B in peak signal-to-noise ratio on simulated benchmark datasets) and a shorter running time than existing SOTA algorithms by a large margin. The code and models are publicly available at http://gffzz188fe103f8f1460as9oxkuxw5o9vv6okw.ffgz.tsg.suse.edu.cn/ucaswangls/GAP-CCoT. | LISHUN WANG ZONGLIANG WU YONG ZHONG XIN YUAN | 2022 | Photonics Research2022，10，8： | 1 |
| 8 | Drug Target Identification Using Affinity Core-Shell Magnetic Nanoparticles and Mass Spectrometry显示文摘亲密关系核心壳当与基于的 nano 高效的液体层析双人脚踏车团 spectrometry (HPLC-MS/MS ) 在联合使用了时,磁性的 nanoparticles (MNP ) 为在房间 lysate 识别药的目标蛋白质作好准备猎枪 proteomic 分析。cyclosporine A (CsA ) 的很多个新潜在的目标能被识别,由于在药目标鉴定的亲密关系 MNP 的高功效。就我们的知识而言,这是第一次揭示 CsA 的如此的一个丰富的目标系列。 | Yunhuan Wei Tongdan Wang Chao Liu Qianqian Zhang Lishun Wang Gongli Tang Jingwu Kang | 2013 | Chinese Journal of Chemistry2013，31，6： | 1 |
| 9 | Residence time distribution and modeling of the liquid phase in an impinging stream reactor显示文摘Based on some experimental investigations of liquid phase residence time distribution(RTD)in an impinging stream reactor,a two-dimensional plug-flow dispersion model for predicting the liquid phase RTD in the reactor was proposed.The calculation results of the model can be in good agreement with the experimental RTD under different operating conditions.The axial liquid dispersion coefficient increases monotonously with the increasing liquid flux,but is almost independent of gas flux.As the liquid flux and the gas flux increase,the liquid dispersion coefficient of center-to-wall decreases.The axial liquid dispersion coefficient is much larger than that of center-to-wall,which indicates that the liquid RTD is dominated mainly by axial liquid dispersion in the impinging stream reactor. | Xingjun WANG Xianhui HU Lishun HU Guangsuo YU Fuchen WANG | 2010 | Frontiers of Chemical Science and Engineering2010，4，3： | 1 |
| 10 | 显示文摘 | Wu Lishun Sun Junfen Wang Qingrui | 2006 | Journal of Mem- brane Science2006，285，12： | 1 |
| 11 | Existence results for semiposition boundary value problems显示文摘 | Ma Ruyun Wang Rufa Ren Lishun | 2001 | Acta Mathematics Sinica2001，21，2： | 1 |
| 12 | Overview coking plant & Lurgi gasifier plant waste water treatment显示文摘The paper described the coking plant and Lurgi gasifier plant waste water types and characteristics , comparing the COD and ammonia-N level in different source of waste water in the plant.The currently maturity coking plant waste water treatment method was statement in the paper and analyzed the pros and cons of each method.The primary cost analysis of each type of waste water treatment was also completed in the paper.According to these analyses , recommendation was prepared for coking plant and Lurgi gasifier plant waste water treatment. | HU Lishun 1 , WANG Sijing 2 , HUANG Yan 2 , XUE Junli 1 ( 1 Fuels and Emissions Lab , GE Global Research Shanghai , Shanghai , China 2 GE Energy-Power & Water , Shanghai , China ) | 2012 | 化工进展2012，31，S1： | 0 |
| 13 | Efficacy and Safety of Tirofiban in Thrombolytic Therapyfor Ischemic Stroke显示文摘Objective:To evaluate the efficacy and safety of tirofiban hydrochloride in the treatment of ischemic stroke with thrombolytic therapy.Method:Two hundred patients with acute ischemic stroke thrombolysis were randomly divided into the experimental group and the control group.The experimental group was given tirofiban with the addition of rtpa in the control group and the therapeutic effects of the two groups were compared.Results:In comparison with the control group,the NIHSS improvement rate was 98%in the experimental group within 14 days.The platelet aggregation rate and efficacy in the experimental group were significantly reduced than the control group(P<0.01).The major adverse reaction in the two groups was hemorrhage with an incidence rate of 3%.Conclusion:Tirofiban hydrochloride is a highly effective and selective platelet glycoprotein Ⅱb/Ⅲa receptor inhibitor,which is safe and effective in combination with heparin and aspirin. | Ruixian Wang Lishun Yang Jianhui Zhang Qingping Yao Zihuan Zhang | 2020 | Journal of Clinical and Nursing Research2020，4，1： | 0 |
| 14 | Aldh2 deficiency plays a dual role in lung tumorigenesis and tumor progression显示文摘Alcohol consumption contributes to global mortality and cancer development.Acetaldehyde(ACE),the oxidized metabolite of alcohol,is highly reactive towards DNA,resulting in DNA adducts.ACE can be detoxified to acetate by acetaldehyde dehydrogenase type 2(ALDH2).ALDH2 deficiency can lead to ACE accumulation and DNA damage. | Hongjia Zhang Xueqian Sun Zhanming Li Tingting Liu Fang Zhang Xinyu Meng Kaimi Li Jianhua Xu Wei He Bo Jing Tong Wang Na Ni Beibei Sun Feng Yao Yadi Wu Qi Wang Jing Du Eugene Y.Chin Binhua P.Zhou Ping Jiang Lishun Wang Jiong Deng | 2024 | Genes & Diseases2024，11，3： | 0 |
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