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| 1 | A Review of Seasonal Climate Prediction Research in China显示文摘The ultimate goal of climate research is to produce climate predictions on various time scales. In China, efforts to predict the climate started in the 1930 s. Experimental operational climate forecasts have been performed since the late 1950 s,based on historical analog circulation patterns. However, due to the inherent complexity of climate variability, the forecasts produced at that time were fairly inaccurate. Only from the late 1980 s has seasonal climate prediction experienced substantial progress, when the Tropical Ocean and Global Atmosphere project of the World Climate Research program(WCRP) was launched. This paper, following a brief description of the history of seasonal climate prediction research, provides an overview of these studies in China. Processes and factors associated with the climate variability and predictability are discussed based on the literature published by Chinese scientists. These studies in China mirror aspects of the climate research effort made in other parts of the world over the past several decades, and are particularly associated with monsoon research in East Asia. As the climate warms, climate extremes, their frequency, and intensity are projected to change, with a large possibility that they will increase. Thus, seasonal climate prediction is even more important for China in order to effectively mitigate disasters produced by climate extremes, such as frequent floods, droughts, and the heavy frozen rain events of South China. | WANG Huijun FAN Ke SUN Jianqi LI Shuanglin LIN Zhaohui ZHOU Guangqing CHEN Lijuan LANG Xianmei LI Fang ZHU Yali CHEN Hong ZHENG Fei | 2015 | Advances in Atmospheric Sciences2015,32,2: | 20 |
| 2 | Tetrahedral Framework Nucleic Acid-Based Delivery of Resveratrol Alleviates Insulin Resistance:From Innate to Adaptive Immunity显示文摘Obesity-induced insulin resistance is the hallmark of metabolic syndrome,and chronic,low-grade tissue inflammation links obesity to insulin resistance through the activation of tissue-infiltrating immune cells.Current therapeutic approaches lack efficacy and immunomodulatory capacity.Thus,a new therapeutic approach is needed to prevent chronic inflammation and alleviate insulin resistance.Here,we synthesized a tetrahedral framework nucleic acid(tFNA)nanoparticle that carried resveratrol(RSV)to inhibit tissue inflammation and improve insulin sensitivity in obese mice.The prepared nanoparticles,namely tFNAs-RSV,possessed the characteristics of simple synthesis,stable properties,good water solubility,and superior biocompatibility.The tFNA-based delivery ameliorated the lability of RSV and enhanced its therapeutic efficacy.In high-fat diet(HFD)-fed mice,the administration of tFNAs-RSV ameliorated insulin resistance by alleviating inflammation status.tFNAs-RSV could reverse M1 phenotype macrophages in tissues to M2 phenotype macrophages.As for adaptive immunity,the prepared nanoparticles could repress the activation of Th1 and Th17 and promote Th2 and Treg,leading to the alleviation of insulin resistance.Furthermore,this study is the first to demonstrate that tFNAs,a nucleic acid material,possess immunomodulatory capacity.Collectively,our findings demonstrate that tFNAs-RSV alleviate insulin resistance and ameliorate inflammation in HFD mice,suggesting that nucleic acid materials or nucleic acid-based delivery systems may be a potential agent for the treatment of insulin resistance and obesity-related metabolic diseases. | Yanjing Li Shaojingya Gao Sirong Shi Dexuan Xiao Shuanglin Peng Yang Gao Ying Zhu Yunfeng Lin | 2021 | Nano-Micro Letters2021,13,6: | 4 |
| 3 | On Marcinkiewicz integral with variable kernels显示文摘 | Ding Yong Lin Chincheng Shao Shuanglin | 2004 | Indiana Univ Math J2004,53,: | 1 |
| 4 | The Size and Structure of China's Government Debt显示文摘 | Shiyu Li Shuanglin Lin | 2011 | TheSocial Science Journal 2011(48)2011,,: | 1 |
| 5 | On the Marcinkiewicz integral with variable kernels显示文摘 | Ding Yong Lin Chincheng Shao Shuanglin | 2004 | Indiana Univ Math J2004,53,: | 1 |
| 6 | China's value-added tax reform,capital accumulation,and welfare implications显示文摘 | Shuanglin LIN | 2008 | China Economic Review2008,,19: | 1 |
| 7 | On the Marcinkiewicz integral with variable kernels 显示文摘 | DING Yong LIN Chincheng SHAO Shuanglin | 2004 | India Univ Math J2004,53,3: | 1 |
| 8 | China' s Value-added tax reform, capital accumulation, and welfare implications显示文摘 | Lin Shuanglin | 2008 | China Economic Review2008,,19: | 1 |
| 9 | On the Marcinkiewicz integral with variable kernels显示文摘 | Ding Yong Lin Qincheng Shao Shuanglin | 2004 | Indiana Univ Math J2004,53,3: | 1 |
| 10 | China’s capital tax reforms in an open economy显示文摘 | Shuanglin Lin | 2003 | Journal of Comparative Economics2003,,1: | 1 |
| 11 | The size and structure of China's government debt显示文摘 | LI Shiyu LIN Shuanglin | 2011 | The Social Science Journal2011,,9: | 1 |
| 12 | China' s Government Debt: How Serious?显示文摘 | Lin Shuanglin | 2003 | China: An International Journal2003,,11: | 1 |
| 13 | Education and Economic Development: Evidence from China显示文摘 | Shuanglin Lin | 1997 | Comparative Economic Studies1997,,: | 1 |
| 14 | Gravitational wave astronomy: the current status显示文摘In the centenary year of Einstein's General Theory of Relativity, this paper reviews the current status of gravitational wave astronomy across a spectrum which stretches from attohertz to kilohertz frequencies. Sect. 1 of this paper reviews the historical development of gravitational wave astronomy from Einstein's first prediction to our current understanding the spectrum. It is shown that detection of signals in the audio frequency spectrum can be expected very soon, and that a north-south pair of next generation detectors would provide large scientific benefits. Sect. 2 reviews the theory of gravitational waves and the principles of detection using laser interferometry. The state of the art Advanced LIGO detectors are then described. These detectors have a high chance of detecting the first events in the near future. Sect. 3 reviews the KAGRA detector currently under development in Japan,which will be the first laser interferometer detector to use cryogenic test masses. Sect. 4 of this paper reviews gravitational wave detection in the nanohertz frequency band using the technique of pulsar timing. Sect. 5 reviews the status of gravitational wave detection in the attohertz frequency band, detectable in the polarisation of the cosmic microwave background, and discusses the prospects for detection of primordial waves from the big bang. The techniques described in sects. 1–5 have already placed significant limits on the strength of gravitational wave sources. Sects. 6 and 7 review ambitious plans for future space based gravitational wave detectors in the millihertz frequency band. Sect. 6 presents a roadmap for development of space based gravitational wave detectors by China while sect. 7 discusses a key enabling technology for space interferometry known as time delay interferometry. | BLAIR David JU Li ZHAO ChunNong WEN LinQing CHU Qi FANG Qi CAI RongGen GAO JiangRui LIN XueChun LIU Dong WU Ling-An ZHU ZongHong REITZE David H. ARAI Koji ZHANG Fan FLAMINIO Raffaele ZHU XingJiang HOBBS George MANCHESTER Richard N. SHANNON Ryan M. BACCIGALUPI Carlo GAO Wei XU Peng BIAN Xing CAO ZhouJian CHANG ZiJing DONG Peng GONG XueFei HUANG ShuangLin JU Peng LUO ZiRen QIANG Li'E TANG WenLin WAN XiaoYun WANG Yue XU ShengNian ZANG YunLong ZHANG HaiPeng LAU Yun-Kau NI Wei-Tou | 2015 | Science China(Physics,Mechanics & Astronomy)2015,58,12: | 1 |
| 15 | Government Debt and Economic Growth in an Overlapping Generations Model显示文摘 | Shuanglin Lin | | 0,,03: | 1 |
| 16 | Government Debt and Economic Growth in an Overlapping Generations Model显示文摘 | LIN Shuanglin 2000 | 2000 | Southern Economic Journal2000,66,3: | 1 |
| 17 | cross - region FDI productivity spillovers in transition econ-omies :evidence from China 显示文摘 | Tian Xiaowen Vai lo Lo Lin Shuanglin | 2011 | Post ~ Communist Econ-omies2011,23,1: | 1 |
| 18 | Government Debt and Economic Growth in an Overlapping Generations Model显示文摘 | Shuanglin Lin | 2000 | Southem Economic Journal2000,66,3: | 1 |
| 19 | China's Capital Tax Reforms in an Open Economy显示文摘 | Shuanglin | 2004 | Journal of Comparative Economics2004,32,: | 1 |
| 20 | Tetrahedral framework nucleic acid carrying angiogenic peptide prevents bisphosphonate-related osteonecrosis of the jaw by promoting angiogenesis显示文摘The significant clinical feature of bisphosphonate-related osteonecrosis of the jaw(BRONJ)is the exposure of the necrotic jaw.Other clinical manifestations include jaw pain,swelling,abscess,and skin fistula,which seriously affect the patients’life,and there is no radical cure.Thus,new methods need to be found to prevent the occurrence of BRONJ.Here,a novel nanoparticle,t FNA-KLT,was successfully synthesized by us,in which the nanoparticle tetrahedral framework nucleic acid(tFNA)was used for carrying angiogenic peptide,KLT,and then further enhanced angiogenesis.TFNA-KLT possessed the same characteristics as tFNA,such as simple synthesis,stable structure,and good biocompatibility.Meanwhile,tFNA enhanced the stability of KLT and carried more KLT to interact with endothelial cells.First,it was confirmed that tFNA-KLT had the superior angiogenic ability to tFNA and KLT both in vitro and in vivo.Then we apply tFNA-KLT to the prevention of BRONJ.The results showed that tFNA-KLT can effectively prevent the occurrence of BRONJ by accelerating angiogenesis.In summary,the prepared novel nanoparticle,tFNA-KLT,was firstly synthesized by us.It was also firstly confirmed by us that tFNA-KLT significantly enhanced angiogenesis and can effectively prevent the occurrence of BRONJ by accelerating angiogenesis,thus providing a new avenue for the prevention of BRONJ and a new choice for therapeutic angiogenesis. | Dan Zhao Dexuan Xiao Mengting Liu Jiajie Li Shuanglin Peng Qing He Yue Sun Jingang Xiao Yunfeng Lin | 2022 | International Journal of Oral Science2022,14,2: | 0 |