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| 1 | The record of paleoclimatic change from stalagmites and the determination of termination II in the south of Guizhou Province, China显示文摘A high-resolution climate record from 163.00 kaBP to 113.80 kaBP has been obtained through TIMS-U series dating and carbon and oxygen isotope analysis of the three large stalagmites from two caves in the south of Guizhou Province, China. The record of the oxygen isotopes from the stalagmites reveals that the undulation characteristics between the cooling event of the glacial period and the warming event of the interglacial period in the research area can compare well to those of ice cores, lake sediments, loess and deep sea sediments on the scale of ten-thousand years or millennium time scale. The climate undulation provided by the record of the stalagmites has a coherence with the global changes and a tele-connection to the paleoclimate changes in the north polar region. Our results suggest that the direct dynamics of paleo-monsoon circulation changes reflected in the record of the stalagmites might be caused by changes of the global ice volume, and in turn related to various factors, including the solar radiation strength at the mid-latitudes in the Northern Hemisphere, the southern extension of the ice-rafted event in the North Atlantic, and changes of the equatorial Pacific sea surface temperature at the low-latitudes. Using δ18O values, we have calculated the temperatures and the results show that the temperature difference between the penultimate glacial period (with an average temperature of 8.1℃, and a minimum temperature range from 0.65℃ to -1.43℃ at stage 6 ) and the last interglacial period (with an average temperature of 18.24℃ at sub-stage 5e ) was about 10℃. This temperature difference from the record of the stalagmites corresponds in general to the record temperature variation (about 10℃) of measured ice cores. The climate records from the three stalagmites in the two caves have shown that the circulation strength of the Asian summer monsoon and the winter monsoon in the penultimate glacial period and the last interglacial period had a clear change. With the TIMS-U series method, termination II of the penultimate glacial period has been precisely dated at an age of (129.28±1.10) kaBP for the three stalagmites in the south of Guizhou Province, China. This borderline age represents the beginning of the last interglacial period or the boundary between the Middle Pleistocene and the Late Pleistocene, and corresponds to the beginning age of the last interglacial period shown by the ice cores and in the SPECMAP curve of the marine oxygen isotopes. The chronology determination of termination II is not only of stratigraphic and chronological significance, but also lays an important foundation for discussing the short time scales of climate oscillation and rapidly changing events of paleoclimate in the circulation region of the East Asian monsoon. | ZHANG Meiliang, YUAN Daoxian1, LIN Yushi, CHENG Hai, QIN Jiaming &ZHANG HuilingKarst Dynamics Laboratory, Institute of Karst Geology, Chinese Academy of Geological Sciences, Guilin 541004, China Geography Department, Minnesota University, MN 55455, USA Correspondence should be addressed to Zhang Meiliang | 2004 | Science China Earth Sciences2004，47，1： | 9 |
| 2 | 遗传性肥胖与心房颤动的关系显示文摘观察性研究已经确定了体质量指数(body mass index,BMI)与心房颤动之间的关联。然而,从观察性研究中推断因果关系会受到混杂因素、逆因果关系和偏倚的影响。该研究的主要目的是应用BMI的遗传学预测因子评估BMI与心房颤动之间的因果关系。方法:纳入1987-2002年期间在美国、冰岛和荷兰实施的7个前瞻性人群队列研究中基线无心房颤动的欧洲血统个体51 646人, | 刘莉 叶鹏 Chatterjee NA Giulianini F Geelhoed B Lunetta KL Misialek JR Niemeijer MN Rienstra M Rose LM Smith AV Arking DE Ellinor PT Heeringa J Lin H Lubitz SA Soliman EZ Verweij N Alonso A Benjamin EJ Gudnason V Stricker BH van der Harst P Chasman DI Albert CM | 2017 | 中华高血压杂志2017，25，2： | 2 |
| 3 | Bad design, bad practices, bad bugs: frustrations in controlling an outbreak of Elizabe- thkingia meningoseptica in intensive care units 显示文摘 | Balm MN Salmon S Jureen R Teo C Mahdi R Seetoh T Teo JT Lin RT Fisher DA | 2013 | J Hosp Infect2013，85，2： | 1 |
| 4 | Lymphocyte subset and antigen-specifil IgE antibody in nasal polyps 显示文摘 | Lin cm Shunct Hsu MN | 1999 | Ann Allergy1999，2，： | 1 |
| 5 | Use of a single-tube nested real-time PCR assay to facilitate the early diagnosis of acute Q fever显示文摘 | Hou MY Hung MN Lin PS | 2011 | Japanese Journal of Infectious Diseases2011，64，2： | 1 |
| 6 | Proadipogenic effect of leptin on rat preadipocytes in vitro : activation of MAPK and STAT3 signaling pathways 显示文摘 | Machinal-Qu lin F Dieudonn MN Leneveu MC | 2002 | Am J Physiol Cell Physiol2002，282，4： | 1 |
| 7 | A study on the personal traits and knowl- edge |vase of Taiwanev medical students folhing problem-lcmsed learning instructions显示文摘 | Luh SP Yu MN Lin YR | 2007 | Ann Acad Med Singapore2007，36，9： | 1 |
| 8 | Measurement of toxic volatile or- ganic compounds in indoor air of semiconductor foundries using muhi- sorbent adsorption/thermal desorption coupled with gas chromatography - mass spectrometry 显示文摘 | Wu CH Lin MN Feng CT | 2003 | Journal of Chromatography A2003，996，12： | 1 |
| 9 | An updated review on asbestos and related diseases in China显示文摘 | COURTICE MN LIN S WANG X | 2012 | Int J Occup Environ Health2012，18，3： | 1 |
| 10 | A study on the personal traits and knowledge base of Taiwanese medical students following problem- based learning instructions 显示文摘 | Lu SP Yu MN Lin YR | 2007 | Annals academy of medicine2007，36，9： | 1 |
| 11 | An updated review on asbestos and related diseases in China 显示文摘 | Courtice MN Lin S Wang X | 2012 | Int J Oecup Environ Health2012，18，3： | 1 |
| 12 | Food-drug interaction of(-)-epigallocatechin-3-gallate on the pharmacokinetics of irinotecan and the metabolite SN-38显示文摘 | Lin LC Wang MN Tsai TH | | 0，，03： | 1 |
| 13 | Education and psychological support meet the supportive care needs of Taiwanese women three months after surgery for newly diagnosed breast cancer: A non randomised quasi-experimental study显示文摘 | Liao MN Chen SC Lin YC | 2014 | International journal of nursing studies2014，51，3： | 1 |
| 14 | Toxicity and cardiac effects of carbaryl in early developing zebrafish (Danio rerio) embryos显示文摘 | Lin CC Hui MN Cheng SH | 2007 | Toxicol Appl Pharmacol2007，222，2： | 1 |
| 15 | Automated assay of telomere length measurement and informatics for 100,000 subjects in the genetic epidemiology research on adult health and aging (GERA) cohort 显示文摘 | Lapham K Kvale MN Lin J | 2015 | Genetics2015，200，4： | 1 |
| 16 | Education and psychological sup- port meet the supportive care needs of Taiwanese women three months after surgery for newly diagnosed breast cancer: a non-randomised quasi-experimental study显示文摘 | Liao MN Chen SC Lin YC | 2014 | Int J Nurs Stud2014，51，3： | 1 |
| 17 | Toxicity and cardiac effects of carbaryl in early developing zebrafish (Danio rerio) embryos显示文摘 | Lin CC Hui MN Cheng SH | | 0，，02： | 1 |
| 18 | Percutaneous pacemaker or implantable eardioverter-defibrillator lead removal in an attempt to improve symptomatic tricuspid regurgitation 显示文摘 | Nazmul MN Cha YM Lin G | 2013 | Europace2013，15，3： | 1 |
| 19 | Recent developments in electrospinning of nanofiber yarns显示文摘 | Shuakat MN Lin T | 2014 | J Nanosci and Nanotechnol2014，14，2： | 1 |
| 20 | A study on the personal traits and knowledge base of Taiwanese medical students following problem based learning instructions显示文摘 | Luh SP Yu MN Lin YR | 2007 | Ann Acad Med Singapore2007，36，9： | 1 |
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