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| 1 | Analysis of Corneal Spherical Aberration in Patients before and after Phacoemulsification显示文摘Purpose:To investigate the distribution and changes in corneal four-order spherical aberration Z40 in patients with age-related cataract before and after phacoemulsification,and to direct the application of aspherical intraocular lens (IOL)in PHACO combined with IOL implantation.Methods:A total of 155 eyes in 93 patients with age-related cataract were included.All patients received a comprehensive ophthalmologic examination.Corneal Z40 at a pupil diameter of 6 mm was measured by using a Scheimpflug photography system (Pentacam) preoperatively and 3 months postoperatively.Results:The mean corneal Z40 before and after the PHACO at a diameter of 6 mm was(0.294 ±0.138)μm and(0.271 ± 0.130)μm,respectively,with statistical significance(P<0.05, t =4.384).There was no significant difference between male (n=45, 76 eyes) and female patients (n=48,79 eyes) regard- ing corneal Z40 (t=-0.418,P=0.676).The corneal Z40 for patients (35 eyes) aged from 50 to 59 years was (0.238±0.104) μm preoperatively;(0.308 ±0.104)μm for 60 to 69 years; (0.332±0.151)μm for 70 to 79 years; and (0.307±0.164) μm for 80 to 89 years.A significant difference in Z40 was observed among different age groups.A linear positive correlation was noted between corneal Z40 and ages (r=0.203,P<0.003). Conclusion:The corneal Z40 varied significantly among cataract patients. Patients' corneal Z40 , which should be considered when choosing aspherical IOL, increases slightly with age.Thus,customized aspheric IOLs are needed. | Liexi Jia Yifei Huang Zhaohui Li | 2012 | Eye Science2012，27，4： | 6 |
| 2 | Evaluation of the Consistency of Total Spherical Aberration before and after Aspherical Intraocular Lens Implantation显示文摘Purpose:.To analyze the consistency between preoperatively estimated and postoperatively measured total spherical aberration and to evaluate the feasibility of personalized selection of an aspherical intraocular lens(IOL) based on the corneal spherical aberration measured by the Scheimpflug photography system(Pentacam).Methods:.A total of 47 patients.(82 eyes).with age-related cataract received a comprehensive ophthalmologic examination..Corneal spherical aberration was measured by using the Scheimpflug photography system. Patients with corneal spherical aberration ≤0.3 μm were implanted with a zero-spherical aberration advanced optics(AO) aspherical intraocular lens and those with corneal spherical aberration >0.3 μm received a Tecnis ZA9003 aspherical lens(-0.27 μm spherical aberration). Preoperative total remnant spherical aberration was estimated and actual total spherical aberration was measured 3months postoperatively. The consistency between preoperative and postoperative spherical aberration was analyzed by t-test,correlation analysis, and Blant-Altman plots.Results: The estimated and measured values of total spherical aberration were(0.189±0.151) μm and(0.141±0.131) μm,with a statistical difference(t=5.347,P<0.01). For 45 eyes implanted with AO lenses, preoperatively estimated and postoperatively measured total spherical aberration were(0.268±0.137) μm and(0.214 ±0.103) μm. For 37 eyes implanted with Tecnis ZA9003, preoperative estimate of total spherical aberration was(0.092±0.103) μm and postoperative measured value was(0.054±0.106) μm. Statistical significance was noted, as was a positive linear correlation between preoperative and postoperative values(γ=0.846,P<0.01). Bland-Altman analysis showed high consistency between the estimated and measured spherical aberration.Conclusion: The estimated total spherical aberration measured preoperatively differed from the value measured postoperatively, but the two values showed good agreement. It is clinically feasible to conduct personalized selection of asphericalIOL based on Scheimpflug photography system(Pentacam) to measure corneal spherical aberration. | Liexi Jia Zhaohui Li | 2013 | Eye Science2013，28，3： | 2 |
| 3 | Expression of recombinant hybrid peptide cecropinA(1–8)–magainin2(1–12) in Pichia pastoris : Purification and characterization显示文摘 | Fengliang Jin Xiaoxia Xu Liexi Wang Wenqing Zhang Dexiang Gu | 2006 | Protein Expression and Purification2006，，2： | 1 |
| 4 | Expression of recombinant hybrid peptide cecropinA (1-8)-magainin2 (1-2)in Pichia pastoris显示文摘 | JIN Fengliang XU Xiaoxia WANG Liexi | 2006 | Protein Expression and Purification2006，50，2： | 1 |
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