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| 1 | Infectious, atopic and inflammatory diseases, childhood adversities and familial aggregation are independently associated with the risk for mental disorders: Results from a large Swiss epidemiological study显示文摘AIM To examine the associations between mental disorders and infectious, atopic, inflammatory diseases while adjusting for other risk factors.METHODS We used data from PsyC oL aus, a large Swiss Population Cohort Study(n = 3720; age range 35-66). Lifetime diagnoses of mental disorders were grouped into the following categories: Neurodevelopmental, anxiety(early and late onset), mood and substance disorders. They were regressed on infectious, atopic and other inflammatory diseases adjusting for sex, educational level, familial aggregation, childhood adversities and traumatic experiences in childhood. A multivariate logistic regression was applied to each group of disorders. In a complementary analysis interactions with sex were introduced via nested effects. RESULTS Associations with infectious, atopic and other chronic inflammatory diseases were observable together with consistent effects of childhood adversities and familial aggregation, and less consistent effects of trauma in each group of mental disorders. Streptococcal infections were associated with neurodevelopmental disorders(men), and measles/mumps/rubella-infections with early and late anxiety disorders(women). Gastric inflammatory diseases took effect in mood disorders(both sexes) and in early disorders(men). Similarly, irritable bowel syndrome was prominent in a sex-specific way in mood disorders in women, and, moreover, was associated with early and late anxiety disorders. Atopic diseases were associated with late anxiety disorders. Acne(associations with mood disorders in men) and psoriasis(associations with early anxiety disorders in men and mood disorders in women) contributed sex-specific results. Urinary tract infections were associated with mood disorders and, in addition, in a sex-specific way with late anxiety disorders(men), and neurodevelopmental and early anxiety disorders(women).CONCLUSION Infectious, atopic and inflammatory diseases areimportant risk factors for all groups of mental disorders. The sexual dimorphism of the associations is pronounced. | Vladeta Ajdacic-Gross Aleksandra Aleksandrowicz Stephanie Rodgers Margot Mutsch Anja Tesic Mario Müller Wolfram Kawohl Wulf R?ssler Erich Seifritz Enrique Castelao Marie-Pierre F Strippoli Caroline Vandeleur Roland von K?nel Rosa Paolicelli Markus A Landolt Cornelia Witthauer Roselind Lieb Martin Preisig | 2016 | World Journal of Psychiatry2016，6，4： | 2 |
| 2 | Cerebral hyperperfusion syndrome after carotid intervention:a review显示文摘 | Lieb M Shah U Hines GL | 2012 | Cardiol Rev2012，20，2： | 1 |
| 3 | Substance P receptorantagonists-a new antide-pressive and anxiolyric mechanism?显示文摘 | Lieb K Fiebicl BI Berger M | 2000 | Nervenarzt2000，71，9： | 1 |
| 4 | Vasopressin V2 receptor blockade with tolvaptan versus fluid restriction in the treatment of hyponatremia显示文摘 | GHEORGHIADE M GOTI'LIEB SS UDELSON JE | 2006 | Am J Cardiol2006，97，7： | 1 |
| 5 | Near-infrared reflection spectroscopy and partial least squares regression for determining the total carbon coverage of silica packings for liquid chromatography显示文摘 | Heigl N Petter C H Lieb M | 2009 | Vibrational Pectroscopy2009，49，2： | 1 |
| 6 | The response of a layered halfspace to traffic loads moving along its surface显示文摘 | Grundmann H Lieb M Trommer E | 1999 | Archive of Applied Mechanics1999，69，1： | 1 |
| 7 | Clostridium ljungdahlii represents a microbial production platform based on syngas 显示文摘 | K6pke M Held C Hujer S Liesegang H Wiezer A Wollherr A Ehrenreich A Lieb W Gottschalk G Dtirre P | 2010 | Proc Nat Acad Sci2010，107，13： | 1 |
| 8 | Microencapsulated cell-mediated treatment of inoperable pancreatic carcinoma显示文摘 | Matthias L?hr Anne Hoffmeyer Jens-Christian Kr?ger Mathias Freund Johannes Hain Albrecht Holle Peter Karle Wolfram T Kn?fel Stefan Liebe Petra Müller Horst Nizze Matthias Renner Robert M Saller Thomas Wagner Karlheinz Hauenstein Walter H Günzburg Brian Sa | 2001 | The Lancet2001，，9268： | 1 |
| 9 | Cerebral hyperperfusion syndrome after carotid intervention: a review显示文摘 | Lieb M Shah U Hines GL | 2012 | Cardiol Rev2012，20，： | 1 |
| 10 | Using micromulsions for drug delivery 显示文摘 | BHARGAVA H N NARURKAR A LIEB L M | 1987 | Pharmaceutical Technology1987，12，3： | 1 |
| 11 | Cerebral hyperperfusion syndrome after carotid intervention: a review显示文摘 | LIEB M SHAH U HINES G L | 2012 | Cardiol Rev2012，20，2： | 1 |
| 12 | Pathways of inflammatory activation in Alzheimer's disease: potential targets for disease modifying drugs显示文摘 | Hull M Lieb K Fiebich BL | 2002 | Curr Med Chem2002，9，1： | 1 |
| 13 | Parental psychopathology,parenting styles,and the risk of social phobia in offspring:a prospective-longitudipal community study显示文摘 | Wittchen H U Hofler M | 2000 | Arch Gen Psychiatry2000，57，9： | 1 |
| 14 | Evaluation of a field test kit for measuring selected soil quality indicators显示文摘 | Liebing M A Doran J W Gardner J C | 1996 | Agro I1996，88，4： | 1 |
| 15 | Recent developments in pharmacotherapy of alcoholism显示文摘 | Soyka M Lieb M | 2015 | Pharmacopsychiatry2015，48，45： | 1 |
| 16 | Sleep deprivation and growth-hormone secretion 显示文摘 | Lieb K Reineke M Riemann D | 2000 | Lancet2000，356，9247： | 1 |
| 17 | Mediating specific cell adhesion to low-adhesive diblock copolymers by instant modification with cyclic RGD peptides显示文摘 | Lieb E Hacker M Tessmar J | 2005 | Biomaterials2005，26，15： | 1 |
| 18 | Cerebral hyperperfusion syn- drome ater carotid intervention: a review 显示文摘 | Lieb M Shah U Hines GL | 2012 | Cardiol Rev2012，20，2： | 1 |
| 19 | Vertical injec- tion wells for SAGD: a practical option or not显示文摘 | SAWHNEY G S LIEBE H BUTLER R M | 1995 | Journal of Canadian Petroleum Technology1995，34，1： | 1 |
| 20 | 显示文摘 | Neubauer M Lieb K P | 1998 | J Alloys Compounds1998，274，： | 1 |
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