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1Experimental study on the mechanical properties of rocks at high temperature显示文摘The mechanical properties of marble, limestone, and sandstone as well as the stress-strain curve, the varying characteristics of the peak strength, the peak strain and elastic modulus were studied by using the MTS810 Rock Mechanics Servo-controlled Testing System under the action of temperatures rang- ing from room temperature to 800℃ . Results show that (1) the peak strength and elastic modulus of marble fluctuate at the temperature from normal to 400 ℃ ; and they decrease gradually over 400℃ . (2) With the rise of the temperature, the peak strength and elastic modulus of limestone show downward trend from normal temperature to 200 ℃ ; have little change from 200 ℃ to 600 ℃; and decrease sharply over 600 ℃ . (3) The peak strength of sandstone shows a downward trend while a little change for elastic modulus at normal temperature to 200 ℃ ; and from 200 ℃ to 600 ℃ , the peak strength of sandstone in- creases while a little change for elastic modulus; the peak strength and elastic modulus decrease rap- idly at the temperature over 600 ℃ . (4) The peak strain of limestone shows little change at normal tem- perature to 600 ℃ , however, the peak strain increases rapidly over 600 ℃; and for marble and sandstone, the peak strain decreases with the rise of the temperature from normal temperature to 200℃ , the peak strain increases rapidly over 200℃. The result can provide valuable references for the rock engineering design at high temperature.ZHANG LianYing MAO XianBiao LU AiHong 2009Science China(Technological Sciences)2009,52,3:30
2Effect of specimen size on energy dissipation characteristics of red sandstone under high strain rate显示文摘In this experiment, red sandstone specimens, having slenderness ratios of 0.5, 0.7, 0.9 and 1.1 respectively, were subjected to blow tests using a Split Hopkinson Pressure Bar(SHPB) system at a pressure of 0.4 atmospheres. In this paper, we have analyzed the effect of slenderness ratio on the mechanical properties and energy dissipation characteristics of red sandstone under high strain rates. The processes of compaction, elastic deformation and stress softening deformation of specimens contract with an increase in slenderness ratio, whilst the nonlinear deformation process extends correspondingly. In addition, degrees of damage of specimens reduced gradually and the type of destruction showed a transformation trend from stretching failure towards shear failure when the slenderness ratio increased. A model of dynamic damage evolution in red sandstone was established and the parameters of the constitutive model at different ratios of length to diameter were determined. By comparison with the experimental curve, the accuracy of the model, which could reflect the stress–strain dynamic characteristics of red sandstone, was verified. From the view of energy dissipation, an increase in slenderness ratio of a specimen decreased the proportion of energy dissipation and caused a gradual fall in the capability of energy dissipation during the specimen failure process. To some extent, the study indicated the effects of slenderness ratios on the mechanical properties and energy dissipation characteristics of red sandstone under the high strain rate, which provides valuable references to related engineering designs and academic researches.Li Ming Mao Xianbiao Lu Aihong Tao Jing Zhang Guanghui Zhang Lianying Li Chong 2014International Journal of Mining Science and Technology2014,24,2:24
3Response to Hepatocarcinoma Hca-F of Mice Immunized with Heat Shock Protein 70 from Elemene Combo Tumor Cell Vaccine显示文摘为了分析有免疫力的反应到老鼠的鼠科的 hepatocarcinoma Hca-F,与热吃惊使免疫(HSP70 ) 蛋白质 70 源于 elemene 组合肿瘤 Hca-F 的房间疫苗(EC-TCV ) , HSP70 被自动数据处理从 EC-TCV 孤立亲密关系层析。老鼠 intraperitoneally 与 HSP70 被使免疫三次,怒气房间被取样。为房间,他们对 Hca-F 的增长和 cytotoxicity 与 MTT 试金被测量,他们的显型与流动 cytometry 被分析。有 HSP70 的使免疫的鼠标的怒气房间比与 EC-TCV 使免疫的鼠标的比正常控制鼠标,而是更少的有势力的对 Hca-F 和增长展出了更多的有势力 cytotoxicity。在三个组之中,在与 HSP70 (35.5%) 使免疫的老鼠的 T 淋巴细胞的百分比在正常老鼠与 6.25% 相比是最高的,并且 28.4% 与 EC-TCV 在老鼠使免疫。从 EC-TCV 导出的 HSP70 的免疫能得到有势力免疫者反应到 Hca-F。HSP70 是对 Hca-F 导致反肿瘤免疫者回答的元素之一。细胞与分子的免疫学。2006; 3 (4 ): 291-295。Lianying Guo Guangxia Shi Zhihong Gao Jie Shen Rong Xing Zhenchao Qian 2006Cellular & Molecular Immunology2006,3,4:13
4Effects of strain rates on mechanical properties of limestone under high temperature显示文摘The experimental tests for limestone specimens at 700 °C in uniaxial compression were carried out to inves- tigate the mechanical effects of loading rates on limestone by using a MTS810 rock mechanics servo- controlled testing system considering the loading rate as a variable. The mechanical properties of limestone such as the stress-strain curve, variable characteristics of peak strength and the modulus of elasticity of limestone were studied under the strain rates ranging from 1.1 10à5 to 1.1 10à1 sà1. (1) Sharp decreases were shown for the peak strength and elastic modulus of limestone from 1.1 10à5 to 1.1 10à4 sà1 at 700 °C as well as a downward trend was shown from 1.1 10à4 to 1.1 10à1 sà1 with the rise of the strain rate. (2) The peak strain increased from 1.1 10à5 to 1.1 10à4 sà1, however, there was no obvious changes shown for the peak strain of limestone from 1.1 10à4 to 1.1 10à1 sà1. These results can provide valuable references for the rock blasting effect and design of mine.Tang Furong Mao Xianbiao Zhang Lianying Yin Huiguang Li Yan 2011Mining Science and Technology2011,21,6:10
5Effect of loading rates on the characteristics of thermal damage for mudstone under different temperatures显示文摘The uniaxial compression tests for mudstone specimens are carried out with four different loading rates from room temperature to 400℃ by using the Rock Mechanics Servo-controlled Testing System MTS810 and high temperature furnace MTS652.02.The mechanical properties of mudstone with various loading rates are studied under different temperature conditions.The results show that when temperature increases from room temperature to 400℃ and loading rate is less than 0.03 mm/s,the peak strength of mudstone specimen decreases as loading rate increases,while the various peak strengths show significant differences when loading rate exceeds 0.03 mm/s.At room temperature,the elastic modulus decreases at the first time and then increases with loading rate rising.When the temperature is between200 and 400℃,the elastic modulus presents a decreasing trend with increasing loading rate.With increasing the loading rate,the number of fragments in mudstone becomes larger and even the powder is observed in mudstone with higher loading rate.Under high loading rate,the failure mode of mudstone specimens under different temperatures is mainly conical damage.Mao Rongrong Mao Xianbiao Zhang Lianying Liu Ruixue 2015International Journal of Mining Science and Technology2015,25,5:7
6Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage显示文摘Asparaginyl endopeptidase (AEP ) 是有为在 P1 地点的天门冬素残余的偏爱的 endo/lysosomal 半胱氨酸 endopeptidase 并且在像使用费的受体 3/7/9 的成熟起一个重要作用。AEP 被知道为催化激活在酸的 pH 经历 autoproteolytic 成熟。这里,我们描述 AEP 酶原的水晶结构和 AEP 的成熟形式。在 AEP 和 caspases 之间的结构的比较在关键残余的作文并且在催化机制揭示了类似。Mutagenesis 研究作为为肽底层的劈开是必要的残余识别了 N44, R46, H150, E189, C191, S217/S218 和 D233。在成熟期间, AEP 的帽子领域的 autoproteolytic 劈开在核心领域上开创存取到活跃地点。出人意料地,一个中间的 autoproteolytic 成熟阶段被发现在近似 pH 4.5 在哪个部分激活的 AEP 能被颠倒回到它的酶原形式。这个唯一的特征被 AEP pH4.5 (AEP 在 pH 被成熟 4.5 并且在 pH 结晶 8.5 ) ,在哪个破肽契约被重新绑扎,结构被转变回到它的酶原形式。另外, AEP 禁止者 cystatin C 能被充分激活的 AEP 消化,但是不能被激活的组织蛋白酶消化。因此,我们第一次证明 cystatins 可以为活跃地点通过底层竞争调整 AEP 的活动。Lixia Zhao Tian Hua Christopher Crowley Heng Ru Xiangmin Ni Neil Shaw Lianying Jiao Wei Ding Lu Qu Li-Wei Hung Wei Huang Lei Liu Keqiang Ye Songying Ouyang Genhong Cheng Zhi-Jie Liu 2014Cell Research2014,24,3:6
7Mechanism of the Rpn13-induced activation of Uch37显示文摘Lianying Jiao Songying Ouyang Neil Shaw Gaojie Song Yingang Feng Fengfeng Niu Weicheng Qiu Hongtao Zhu Li-Wei Hung Xiaobing Zuo V. Eleonora Shtykova Ping Zhu Yu-Hui Dong Ruxiang Xu Zhi-Jie Liu 2014Protein & Cell2014,5,8:4
8Macroscopic and microscopic fracture features of concrete used in coal mine under chlorine salt erosion显示文摘The microscopic morphology and pore structure characteristics of concrete with composite admixtures(fly ash and mineral powder) after chlorine salt erosion were analyzed via scanning electron microscopy(SEM) and mercury injection porosimetry(MIP), providing the basis for the design and maintenance of concrete shafts in coal mines. The above-mentioned characteristics were compared with the macroscopic characteristic of concrete fractures under uniaxial compression. The results show that the macroscopic fracture characteristics of concrete under uniaxial compression change from longitudinal split fracture and oblique section shear fracture to conjugate cant fracture, and the degree of breakage increases.Interface cracks, cement paste cracks, spherical surface cracks, and aggregate cracks appear in concrete under uniaxial compression. In the early stages of corrosion, the original cracks which are obvious are repaired. When the corrosion becomes more serious, cement paste cracks appear, and the number of harmful holes increases while the number of harmless holes decreases. This study also reveals the relationship between the macroscopic properties and microscopic structure of concrete under chloride salt erosion. Finally, the paper preliminarily discussed the relationship between the macroscopic properties and mesoscopic characteristics of concrete under chlorine salt erosion.Li Bing Yin Huiguang Mao Xianbiao Li Yan Zhang Lianying Liu Ruixue Qiu Peitao 2016International Journal of Mining Science and Technology2016,26,3:4
9Neural plasticity after spinal cord injury显示文摘Plasticity changes of uninjured nerves can result in a novel neural circuit after spinal cord injury, which can restore sensory and motor functions to different degrees. Although processes of neural plasticity have been studied, the mechanism and treatment to effectively improve neural plasticity changes remain controversial. The present study reviewed studies regarding plasticity of the central nervous system and methods for promoting plasticity to improve repair of injured central nerves. The results showed that synaptic reorganization, axonal sprouting, and neurogenesis are critical factors for neural circuit reconstruction. Directed functional exercise, neurotrophic factor and transplantation of nerve-derived and non-nerve-derived tissues and cells can effectively ameliorate functional disturbances caused by spinal cord injury and improve quality of life for patients.Jian Liu Xiaoyu Yang Lianying Jiang Chunxin Wang Maoguang Yang 2012Neural Regeneration Research2012,7,5:4
10Exchange-Biased NiFe_(2)O_(4)/NiO Nanocomposites Derived from NiFe-Layered Double Hydroxides as a Single Precursor显示文摘NiFe_(2)O_(4) nanoparticles(<10 nm)embedded in a NiO matrix have been fabricated by calcining the corresponding Ni^(Ⅱ)Fe^(Ⅲ)-layered double hydroxide(LDH)precursors at high temperature(500℃).Compared with the NiFe_(2)O_(4)/NiO nanocomposite obtained by calcination of a precursor prepared by a traditional chemical coprecipitation method,those derived from NiFe-LDH precursors show much higher blocking temperatures(TB)(~380 K).The enhanced magnetic stability can be ascribed to the much stronger interfacial interaction between NiFe_(2)O_(4) and NiO phases due to the topotactic nature of the transformation of the LDH precursor to the NiFe_(2)O_(4)/NiO composite material.Through tuning the Ni^(Ⅱ)/Fe^(Ⅲ) molar ratio of the NiFe-LDH precursor,the NiFe_(2)O_(4) concentration can be precisely controlled,and the TB value as well as the magnetic properties of the final material can also be regulated.This work represents a successful example of the fabrication of ferro(ferri)magnetic(FM)/antiferrimagnetic(AFM)systems with high magnetic stability from LDH precursors.This method is general and may be readily extended to other FM/AFM systems due to the wide range of available LDH precursors.Xiaofei Zhao Sailong Xu Lianying Wang Xue Duan Fazhi Zhang 2010Nano Research2010,3,3:4
11Land cover changes and the effects of cultivation on soil properties in Shelihu wetland,Horqin Sandy Land,Northern China显示文摘Land cover change plays an essential role in the alternation of soils properties.By field investigation and applying satellite images,land cover information in the Shelihu wetland was carried out in an area of 2,819 hm 2 in 1985,1995,2000,2005,2010 and 2011,respectively,in Horqin Sandy Land.A total of 57 soil sampling sites across Shelihu were chosen in wet meadow(CL0),cropland(CL) and sandy land(SL) according to the spatial characteristics of water body change.Soil texture,organic carbon(SOC),total nitrogen(TN) and total phosphorus(TP) contents,electrical conductivity(EC) and pH were measured at the soil depths of 0-10,10-20 and 20-40 cm to examine the influence of agricultural conversion and continuous cultivation on soil properties.The results showed that the study area was covered by water body in 1985,which gradually declined afterwards and then reclaimed rapidly at a mean annual rate of 132.1 hm 2 /a from wet meadow to cropland since 1995.In 2011,water body was drained and the area was occupied by 10.8% of CL0,76.9% of CL and 12.3% of SL.Large amounts of SOC,TN and TP were accumulated in the above depths in CL0.Soil in CL0 also had higher EC and silt and clay fractions,lower pH than in SL and CL.Soil in SL was seriously degraded with lower contents of SOC,TN and TP than in CL and CL0.SOC,TN content and EC in CL decreased with the increase of cultivation age,while pH showed a reverse trend with significance at plough horizon.The agricultural conversion in Shelihu was driven by the comprehensive factors of precipitation reduction,economic development and intense competitions for irrigation water.Continuous cultivation in this process is not sustainable because of SOC degradation and nutrient content reduction.The key point is that conventional tillage and removal of residuals induced further land degradation.Wetland reclamation for immediate economic interests led to greater costs in the long-term environmental restoration in Horqin Sandy Land.Jie LIANI XueYong ZHAO XiaoAn ZUO ShaoKun WANG XinYuan WANG YongQing LUO 2013Journal of Arid Land2013,5,1:4
12Body sensor networks for ubiquitous healthcare显示文摘Body sensor networks provide a platform for ubiquitous healthcare, driving the diagnosis in hospital static environment to the daily life dynamic context. We realized the importance of sensing of activities, which is not only a dimension of human health but also important context information for diagnosis based on the physiologic data. This paper presents our ubiquitous healthcare system, uCare. It consists of uCare devices and a server system. Currently, the uCare system is designed for cardiovascular disease (CVD) examination and management. The uCare device has been tested in a trial in Beijing Hospital. The uCare system will be further tested in elderly care at home and exercise management in training to measure heart dynamics during training.Wang, Shaofeng Ji, Lianying Li, Aiguang Wu, Jiankang 2011控制理论与应用(英文版)2011,9,1:3
13Meso-structure and fracture mechanism of mudstone at high temperature显示文摘The meso-structure mineral composition and fracture mechanism of uniaxial compressed mudstone samples at high temperature were analyzed by XRD and scanning electron microscopy. The effect of temperature on mudstone composition and fracture mechanism were studied from a meso-structural perspective, and the relationship between meso-structure and macro-mechanical characteristics at high temperature was revealed. The findings demonstrated that the fluctuation in diffraction intensity of kaolinite in the mudstone caused the fluctuation in its mechanical properties. The overall structure underwent a phase change around 600 ℃, which led to the sudden change in the mechanical properties of mudstone samples. When the temperature reached 600 ℃, the crystalline state worsened and kaolinite disappeared; however, some illite was produced, indicating that the chemical reaction of the structure and sudden drop of bearing capacity of the mudstone. Mudstone fracturing at high temperature involves mainly intergranular and transgranular fractures, which are typical in micro-brittle tensile failure. Considering the macro-fracture characteristics of mudstone, the results suggested that macro-fracture under external force corresponds to the meso-fracture.Zhang Lianying Mao Xianbiao Liu Ruixueab Li Yan Yin Huiguang 2014International Journal of Mining Science and Technology2014,24,4:3
14Application of Piezoelectric Actuator and Compliant Structures to Achieve Flapping Wing Motion for a MAV显示文摘Micro Aerial Vehicles(MAVs) are the smallest artificial aircraft.Most of the flapping wings MAVs are powered by electric motors of various capacities.We report in this paper the application of piezoelectric actuators as power system for a flapping wing MAV using a compliant displacement amplification mechanism.The actuator used for this application is a pre-stressed cut piece of TH-7R type Thunder actuator.A two-bar compliant mechanism with two flexures has been developed to convert the linear displacement into angular movement and amplification.The specimens were made from carbon fiber links and nylon flexures.We also proposed to use the product of frequency(F) and tip displacement(D), F * D as a criteria for the characterization of an amplifying mechanism.The best specimen according to this criterion is obtained for a 5mm length flexure specimen made of three layers of nylon.The F*D value obtained for this specimen was(0.58) Hz.m.ANSYS finite element analysis results for different flexural thickness and lengths were obtained and have been compared to the experimental results.The effect of both the thickness and length of the flexure on a particular arrangement has been discussed.Kranti. K. Lal Kummari S. J. Croucher N. J. Lawson E. E. Liani G. Allegri S. Guo Hsien-Chun Chung Z. Huang 2008材料科学与工程学报2008,26,4:3
15The green hydrolysis technology of hemicellulose in corncob by the repeated use of hydrolysate显示文摘To achieve green hydrolysis technology of hemicellulose through repeated using hydrolysate,the hydrolysis of hemicellulose in corncob was studied.The influence of repeated use of corncob hydrolysate on concentrations of D-xylose and L-arabinose was investigated.The loss rates of D-xylose in the prepared D-xylose solutions both with and without corncob,and repeated using corncob hydrolysate under identical acidity condition were discussed.The result shows that D-xylose concentration and L-arabinose concentration are all gradually increasing with the growing time of repeated use of corncob hydrolysate.After the fifth repetition,the concentrations of D-xylose and L-arabinose are 196.7 g·L^(-1)and 22.0 g·L^(-1),respectively.Substance inhibiting the degradation of D-xylose is generated during repeated use of corncob hydrolysate,and the production is further proved by the change of D-xylose concentration and the loss rate of D-xylose over heating time.Lei Guo Yangdong Hu Lianying Wu Chen Liang Weitao Zhang 2018Chinese Journal of Chemical Engineering2018,26,1:2
16A new model in correlating and calculating the solid–liquid equilibrium of salt–water systems显示文摘In this work, a new activity coefficient model was deduced for the correlation of solid–liquid equilibrium(SLE) in electrolyte solutions. The new excess Gibbs energy equation for SLE contains two parts: the single electrolyte item and the mixed electrolyte item. Then a new hypothesis for the reference state of activity coefficients was proposed in the work. Literature data for single electrolyte solution and mixed electrolyte solution systems,with temperature spanning from 273.15 to 373.15 K, were successfully correlated using the developed model.Xianzhen Xu Yangdong Hu Lianying Wu Xia Chen 2016Chinese Journal of Chemical Engineering2016,24,8:2
17Diabetes Mellitus and the Incidence of Colorectal Cancer: An Updated Systematic Review and Meta-Analysis显示文摘Longying Deng Zhifu Gui Lianying Zhao Jianping Wang Lizong Shen 2012Digestive Diseases and Sciences2012,,6:2
18Poly(PEGMA) magnetic nanogels:Preparation via photochemical method,characterization and application as drug carrier显示文摘One-pot synthesis of magnetic nanogels with excellent biocompatibility via the photochemical method is reported in this paper.Poly(PEGMA) modified superparamagnetic nanogels(poly(PEGMA) magnetic nanogels) were synthesized by in-situ polymerization using poly(ethylene glycol) methacrylate(PEGMA) as the monomer and N,N'-methylene-bis-(acrylamide)(MBA) as the cross-linking agent in magnetite aqueous suspension under UV irradiation.The surface functional groups and components of magnetic nanogels were analyzed by Fourier transform infrared spectroscopy(FTIR) and a thermogra-vimetric analyzer(TGA).The results indicated that the poly(PEGMA) magnetic nanogels were synthe-sized successfully by coating poly(PEGMA) on the Fe3O4 nanoparticles under UV irradiation,and the Fe3O4 nanoparticles content in this nanogels was above 50 wt%.The morphology,size,zeta-potential and magnetic property were also characterized.The magnetic nanogels had a nearly spherical shape and core-shell structure,the average size in aqueous system measured by photon correlation spec-troscopy(PCS) was 68.4 nm,which was much bigger than that in the dry state,the nanogels behaved superparamagnetically with saturated magnetization of 58.6 emu/g,and the zeta-potential was-16.3-_17.3 mV at physiological pH(6.8-7.4) which could help to maintain stability in blood.The preliminary application as drug carrier was made and the doxorubicin-loaded magnetic nanogels had an excellent property in slow-release.The experiment indicated that the magnetic nanogel was an ideal candidate carrier in target drug delivery systems and other biomedical application.SUN HanWen ZHANG LianYing ZHU XinJun KONG ChunYan ZHANG CunLan YAO SiDe 2009Science China Chemistry2009,52,1:2
19Ubiquitylation of synphilin-1 and alpha-synuclein by SIAH and its presence in cellular inclusions and Lewy bodies imply a role in Parkinson' s disease显示文摘Liani E Eyal A Avraham E 2004Proc Natl Acad Sci USA2004,101,:1
20Phosphorylation of Parkin by the cyclin-dependent kinase 5 at the linker region modulates its ubiquitin-ligase activity and aggregation显示文摘Avraham E Rott R Liani E 2007J Biol Chem2007,282,12:1
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