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| 1 | Knockdown of STAT3 by shRNA inhibits the growth of CAOV3 ovarian cancer cell line in vitro and in vivo显示文摘抄写 3 的组成地激活的信号变换器和使活跃之物(STAT3 ) 包括卵巢的癌症在许多肿瘤的形成起一个重要作用。在这研究,对 STAT3 特定的 RNA 干扰被采用在 STAT3 发信号的抑制上并且在卵巢的癌症 CAOV3 房间的生长上学习它的效果。对 STAT3 和爬的 shRNA 控制表示特定的小发卡 RNA (shRNA ) 的质粒向量 pGenesil-1-GFP-U6 被构造。在进 CAOV3 房间的转染以后, STAT3 shRNA 明确地在 mRNA 和蛋白质层次压制了 STAT3 表示。同时, Bcl-xL, cyclin D1,和 c-myc 的表情是下面调整的,而劈开的 caspase 3 起来调整。另外,在 CAOV3 细胞的击倒的禁止的抛锚无关的生长和导致的 apoptosis,和在裸体老鼠的减少的肿瘤生长与卵巢的癌症细胞植入的 STAT3。 | Feng Huang Xiaoyun Tong Liangqing Fu Ronghua Zhang | 2008 | Acta Biochimica et Biophysica Sinica2008，40，6： | 18 |
| 2 | Recent advances in acid-resistant zeolite T membranes for dehydration of organics显示文摘Zeolite membranes offer outstanding potentials in separation of many molecular mixtures due to their molecular sieving selectivity and the high thermal and mechanical stability that allow them to operate at harsh conditions.Development of durable and high separation performance membranes with lower fabrication and operation cost are highly demanded for industrial applications. Zeolite T membrane possesses good acid-resistance with excellent hydrophilic properties as compared to NaA zeolite membrane and can be extended to industrial organic dehydrations under an acidic environment. In the present review the research advances in development of zeolite T membranes for the dehydration of organic mixtures in acidic conditions are summarized. Especially the low temperature synthesis, and epitaxial growth of the zeolite membrane with high performance are well addressed, besides emphasis is particularly placed on ensemble synthesis of hollow fiber zeolite T membrane module and its future prospects for industrial separations. | Yiwei Luo Waseem Raza Jianhua Yang Liangqing Li Ying Lu | 2019 | Chinese Journal of Chemical Engineering2019，27，6： | 4 |
| 3 | The influence of ^(18)F-fluorodeoxyglucose positron emission tomography/computed tomography on the N-and M-staging and subsequent clinical management of intrahepatic cholangiocarcinoma显示文摘Background:Intrahepatic cholangiocarcinoma(ICC)is a highly metastatic cancer.^(18)F-fluorodeoxyglucose positron emission tomography/computed tomography(^(18)F-FDG PET/CT)enables sensitive tumor and metastasis detection.Our aim is to evaluate the influence of pre-treatment PET/CT on the N-and M-staging and subsequent clinical management in ICC patients.Methods:Between August 2010 and August 2018,660 consecutive ICC patients,without prior anti-tumor treatments nor other malignancies,were enrolled.The diagnostic performance of PET/CT on the N-and M-staging was compared with conventional imaging,and the preoperative staging accuracy and treatment re-allocation by PET/CT were retrospectively calculated.Survival difference was compared between patients receiving PET/CT or not after propensity score matching.Results:Patients were divided into group A(n=291)and group B(n=369)according to whether PET/CT was performed.Among 291 patients with both PET/CT and conventional imaging for staging in group A,PET/CT showed significantly higher sensitivity(83.0%vs.70.5%,P=0.001),specificity(88.3%vs.74.9%,P<0.001)and accuracy(86.3%vs.73.2%,P<0.001)than conventional imaging in diagnosing regional lymph node metastasis,as well as higher sensitivity(87.8%vs.67.6%,P<0.001)and accuracy(93.5%vs.89.3%,P=0.023)in diagnosing distant metastasis.Overall,PET/CT improved the accuracy of preoperative staging from 60.1%to 71.8%(P<0.001),and modified clinical treatment strategy in 5.8%(17/291)of ICC patients,with unique roles in different tumor-node-metastasis(TNM)stages.High tumor-to-non-tumor ratio(TNR)predicted poor overall survival[hazard ratio(HR)=2.17;95%confidence interval(CI):1.49-3.15;P<0.001].Furthermore,patients performing PET/CT had longer overall survival compared with those without PET/CT(HR=0.74;95%CI:0.58-0.93;P=0.011)after propensity score matching.Conclusions:PET/CT was valuable for diagnosing regional lymph node metastasis and distant metastasis in ICC patients,and facilitated accurate tumor staging and optimal treatment allocation. | Youpei Lin Huanhuan Chong Guohe Song Chenhao Zhang Liangqing Dong Ling Aye Fei Liang Shuaixi Yang Mengsu Zeng Guangyu Ding Shu Zhang Jieyi Shi Aiwu Ke Xiaoying Wang Jian Zhou Jia Fan Qiang Gao | 2022 | Hepatobiliary Surgery and Nutrition2022，11，5： | 3 |
| 4 | LAPAROSCOPIC RADICAL PROSTATECTOMY:INITINAL EXPREIENCE OF 23 CASES IN SUN YAT-SEN UNIVERSITY显示文摘Objective: To report our prelimilary experience of laparoscopic radical prostatectomy (LRP) for clinically localized prostatic cancer.Methods:23 cases with localized prostatic cancer underwent LRP in our institution from October 2000 to August 2003. The median age was 64.5 years old, the median PSA was 13 ng/ml and median Gleason score of biopsy specimens was < 7. The operations were performed according to Montsouris technique. Briefly, operations were carried out transperitonealty, combining posterior and anterior approachs to the prostate, transecting the bladder neck, lateral dissection of the prostate, urcthrovesical anastomosis, completing the operation.Results:No death and no conversion rate were observed in this series of 23 cases of LRP. No re-intervention was needed. The median operating time was 325 minutes (range 270 to 660 min) including the lymphadenectomy phase that was considered necessary in the case whose PSA value was 51ng/ml and pathological reading was negative to thoses lymph nodes; The median intraoperative blood loss was 430 ml(rang 200 to 1100 ml). Postoperative bladder catheterization time was 20 days. Surgical positive margin was found in I case of pathlogical stage of pT 2b and Casodex 50 mg had been used on this case for 3 mon after the PSA value was < 0.2 ng/ml. Postoperation follow-up of 3 to 24 mo. showed no signs of complications such as urethral stricture or urine incontinence. The PSA concentrations was < 0.3 ng/ml in all cases.Conclusions: LRP provides a clear and magnified anatomical image to allow a more precise and safer dissection. | Gao Xin, Qiu Jianguang,Cai Yubin, Zhou Xiangfu, Hong Liangqing Department of Urology, the Third Affiliated Hospital of Zhongshan University, Guangzhou 510630 | 2003 | 中国内镜杂志2003，9，10： | 2 |
| 5 | Apoptosisinthecornea:furthercharacterizationofFas/Fasligandsystem显示文摘 | 4,MohanRR LiangQ KimWJ,etal | 1997 | ExpEyeRes1997，65，4： | 1 |
| 6 | Topsoil organic carbon storage of China and its loss by cultivation显示文摘 | Song Guohan Li Liangqing Pan Zhenxing | 2005 | Biogeochemistry2005，74，3： | 1 |
| 7 | Genetic sequence stratigraphic framework,depositional style,and hydrocarbon occurrence of the Upper Cretaceous QYN Formations in the Songliao lacustrine basin,northeastern China显示文摘 | Xue Liangqing Galloway W E | 1993 | AAPG1993，77，10： | 1 |
| 8 | Direct correlation between positron emission tomographic images of two reporter genes delivered by two distinct adenoviral vectors显示文摘 | YaghoubiSS WuL LiangQ etal | 2001 | GeneTher2001，8，14： | 1 |
| 9 | Hierarchy a- nalysis for flow units division of low-permeability reservoir:a case study in Xifeng Oilfield, Ordos Basin 显示文摘 | Lv Mingsheng Chen Kaiyuan Xue Liangqing | 2010 | Energy Exploration & Exploitation2010，28，2： | 1 |
| 10 | EasySynthesisof HighlyFluorescentCarbon Quantum Dotsfrom Gelatin andtheirLuminescentPropertiesand Applications显示文摘 | LiangQ H Ma W J ShiY etal | 2013 | Carbon2013，60，42： | 1 |
| 11 | Frequency splitting phenomenon of dual transverse modes in a Nd: YAG laser 显示文摘 | Ding Jinyun Zhang Liangqing Zhang Zhifeng | 2010 | Optics & Laser Technology2010，42，2： | 1 |
| 12 | Frequency splitting phenomenon of dual transverse modes in a Nd: YAG laser 显示文摘 | JINYUN D LIANGQING Z | 2010 | Optics & Laser Technol2010，42，2： | 1 |
| 13 | Spleen-preserving splenic lymph node dissection in radical total gastrectomy显示文摘Radical gastrectomy has been recognized as the standard surgical treatment for advanced gastric cancer, and essentially applied in a wide variety of clinical settings. The thoroughness of lymph node dissection is an important prognostic factor for patients with advanced gastric cancer. Splenic lymph node dissection is required during D2 radical gastrectomy for upper stomach cancer. This is often accompanied by removal of the spleen in the past few decades. A growing number of investigators believe, however, that the spleen plays an important role as an immune organ, and thus they encourage the application of a spleen- preserving method for splenic hilum lymph node dissection. | Zhigang Jie Zhengrong Li Yi Cao Yi Liu Mengmeng Jiang Liangqing Lin Guoyang Zhang | 2013 | Chinese Journal of Cancer Research2013，25，4： | 1 |
| 14 | The Effect of 17 β-Estradiol on Invasion by the Ovarian Clear Cell Adenocarcinoma Cell Line ES-2 and the Molecular Mechanism Involved显示文摘 | Jingxin Ding Youji Feng Lianhuo Yin Hongyan Jin Xiaoxia Liu Liangqing Yao Yunyan Sun | 2005 | Chinese Journal of Clinical Oncology2005，2，4： | 1 |
| 15 | On the classification of simple inductive limit C*-algebras, II: The isomorphism theorem显示文摘 | George A. Elliott Guihua Gong Liangqing Li | 2007 | Inventiones mathematicae2007，，2： | 1 |
| 16 | Genetic sequence stratigraphic framework, delx~itional style, and hydrocarbon occurrence of the Upper Cretaceous QYN formations in the Songliao lacustrine basin,northeastern China显示文摘 | Xue Liangqing Galloway W E | 1993 | AAPG Bulletin1993，77，10： | 1 |
| 17 | Genetic sequence stratigraphic framework,depositional style,and hydrocarbon occurrence of the upper cretaceous QYN formations in the songliao lacustrine basin,northeastern china显示文摘 | XUE Liangqing GALLOWAY W E | 1993 | AAPG Bulletin1993，，10： | 1 |
| 18 | North Atlantic Abrupt Climate Signals during the Last Glacial Period in Central Asia:Evidences from Aeolian Loess Sediments显示文摘Objective Climate fluctuations over suborbital or millennial timescale display significant instability during the last glacial period,which are often superimposed upon the orbital periodicity.They triggered some abrupt climate events,such as the Dansgarrd/Oeschger(D-O)events recorded in the Greenland ice cores and the Heinrich(H) | SONG Yougui LI Yue LI Yun AN Zhisheng CHENG Liangqing SUN Huanyu Rustam OROZBAEV | 2017 | Acta Geologica Sinica(English Edition)2017，91，5： | 1 |
| 19 | Application Effect of Micropore Aeration Technique in Rearing Process of Summer Fingerlings of Silurus asotus from Poyang Lake显示文摘Application effect of micropore aeration technique in rearing process of summer fingerlings of Silurus asotus from Poyang Lake was studied.This study provides an efficient safe aeration solution for large-scale fingerling rearing of Silurus asotus. | Yi YAO Chunxian XIONG Liangqing XU Qinglong JIANG Lan LAN Lougen ZENG | 2016 | Agricultural Biotechnology2016，5，5： | 1 |
| 20 | Treatment experiences of pelvic bone hydatidosis显示文摘 | LiangQ WenH YunusA | 2014 | Int J Infect Dis2014，18，： | 1 |
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