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| 1 | Cervical Cancer Screening Rates Among Chinese Women—China,2015显示文摘What is already known about this topic?Cervical cancer is the fourth most common cancer of women around the world.Age-adjusted incidence and mortality rates of cervical cancer were 11.78 and 3.29 per 100,000,respectively,in China in 2015.What is added by this report?Cervical cancer screening rates were 25.7%for women aged 20–64 years old and 31.4%for women aged 35–64 years old in China in 2015.Screening rates were lower in rural areas than in urban areas and varied across provinces.What are the implications for public health practice?Efforts should be made to continue to strengthen national and local policy initiatives,financial support,health education,and accessibility to women in rural areas for cervical cancer screening coverage. | Mei Zhang Yijing Zhong Zhenping Zhao Zhengjing Huang Xiao Zhang Chun Li Maigeng Zhou Jing Wu Limin Wang Xiaoying Zheng Linhong Wang | 2020 | China CDC weekly2020，2，26： | 17 |
| 2 | Comparison of dynamic adsorption/desorption characteristics of toluene on different porous materials显示文摘Four different types of adsorbents, SBA-15, MCM-41, NaY and SiO2, were used to study the dynamic adsorption/desorption of toluene. To further investigate the influence of pore structure on its adsorption performance, two SBA-15 samples with different microspores were also selected. It is shown that microporous material NaY has the largest adsorption capacity of 0.2873 mL/g, and the amorphous SiO2 exhibits the least capacity of 0.1003 mL/g. MCM-41 also shows a lower break through capacity in spite of the relatively small pore diameter, because it can not provide the necessary small geometric confinement for the tiny adsorbates. However, the mesoporous SBA-15 silica with certain micropore volume shows relatively higher adsorption capacity than that of MCM-41 silica. The presence of micropores directly leads to an increase in the dynamic adsorption capacity of toluene. Although NaY has the highest adsorption capacity for toluene, its complete desorption temperature for toluene is high (> 350°C), which limits its wide application. On the contrary, mesoporous silica materials exhibits a good desorption performance for volatile organic compounds at lower temperatures. Among these materials mesoporous SBA-15 samples, with a larger amount micropores and a lower desorption temperature, are a potentially interesting adsorbent for the removal of volatile organic compounds. This behavior should been related with the best synergetic effect of mesopores and micropores. | Weiwei Zhang Zhenping Qu Xinyong Li Yi Wang Ding Ma Jingjing Wu | 2012 | Journal of Environmental Sciences2012，24，3： | 13 |
| 3 | Research and development of next generation of antibody-based therapeutics显示文摘Monoclonal 抗体(mAb ) 作为在许多人的疾病的治疗的治疗学的代理人的主要的班之一新兴,特别地在癌症和免疫学的混乱。迄今为止, 28 mAb 被美国食物药品管理局为临床的应用同意了。另外,几百 mAb 被许多 biotech 和药品的公司为各种各样的疾病指示临床上正在开发。然而,许多挑战尚待并且治疗学的抗体的完整的潜力还得被认识到。与抗体工程技术的前进和我们疾病生物学以及行动的抗体机制的进一步的理解,新奇抗体格式或抗体的许多班导出分子作为有希望的新一代治疗学正在出现。这些新抗体格式或分子小心地被设计并且设计了获得特殊特征,例如改进 pharmacokinetics,增加的选择,和提高的功效。这些新代理人可以有潜力革命化我们在研究并且发展下一代的努力想和惯例基于抗体的治疗学。 | Jing LI Zhenping ZHU | 2010 | Acta Pharmacologica Sinica2010，31，9： | 11 |
| 4 | Cervical Cancer Screening Coverage — China, 2018–2019显示文摘What is already known about this topic?The World Health Organization set a 2030 target of 70%cervical cancer screening coverage for women aged 35–45 years.Coverage stood at 37%in China in 2015.What is added by this report?In 2018–2019,China’s cervical cancer screening coverage reached 43.4%in women aged 35–44 years and 36.8%in women aged 35–64 years.Screening coverage was still lower in rural areas as well as central and western regions;large variations existed across provincial-level administrative divisions.What are the implications for public health practice?National and local policy and financial support should be maintained for cervical cancer screening,along with more targeted health education and outreach efforts and strengthened accessibility of health services in the rural areas and central and western regions. | Mei Zhang Yijing Zhong Limin Wang Heling Bao Zhengjing Huang Zhenping Zhao Xiao Zhang Chun Li Kelly Liang Sun Jing Wu Xiaoying Zheng Linhong Wang | 2022 | China CDC weekly2022，4，48： | 11 |
| 5 | Numerical Investigations on the Steady and Unsteady Leakage Flow and Heat Transfer Characteristics of Rotor Blade Squealer Tip显示文摘The steady and unsteady leakage flow and heat transfer characteristics of the rotor blade squealer tip were conducted by solving Reynolds-Averaged Navier-Stokes(RANS) equations with k-ω turbulence model.The first stage of GE-E3 engine with squealer tip in the rotor was adopted to perform this work.The tip clearance was set to be 1% of the rotor blade height and the groove depth was specified as 2% of the span.The results showed that there were two vortexes in the tip gap which determined the local heat transfer characteristics.In the steady flow field,the high heat transfer coefficient existed at several positions.In the unsteady case,the flow field in the squealer tip was mainly influenced by the upstream wake and the interaction of the blades potential fields.These unsteady effects induced the periodic variation of the leakage flow and the vortexes,which resulted in the fluctuation of the heat transfer coefficient.The largest fluctuation of the heat transfer coefficient on the surface of the groove bottom exceeded 16% of the averaged value on the surface of the squealer tip. | Jun LI Hao SUN Jinshan WANG Zhenping FENG | 2011 | Journal of Thermal Science2011，20，4： | 9 |
| 6 | Leisure-Time Physical Activity Among Chinese Adults--China, 2015显示文摘What is already known on this topic?Leisure-time physical activity(LTPA)such as sports,fitness,and recreation,is well documented to prevent chronic disease and improve health.The age-adjusted prevalence of regular LTPA was only 11.9%among Chinese adults in China in 2010.It has been reported that the age-adjusted LTPA prevalence increased from 7.13%in 2000 to 11.79%in 2011.What is added by this report?According to the latest available data,in 2015,the prevalence of LTPA and regular LTPA was 19.7%and 12.5%in adults aged 18 years old and above,respectively.Both LTPA and regular LTPA were lower in rural areas than in urban areas,higher in people with higher socioeconomic position,and varied across provinces.What are the implications for public health practice?To promote more people,especially those with lower socioeconomic position to participate in LTPA,great efforts are required to strengthen national and local policy initiatives,financial support,sports facility construction,and health education,especially in rural areas and in western China. | Chun Li Limin Wang Xiao Zhang Zhenping Zhao Zhengjing Huang Maigeng Zhou Jing Wu Mei Zhang | 2020 | China CDC weekly2020，2，35： | 8 |
| 7 | Study on Modification Mechanism of Rare Earth in ZA27 Cast Alloy with Electronic Theory and Molecular Dynamics Method显示文摘A model of liquid ZA27 cast alloy is established according to molecular dynamics theory and an atomic structural model of co-existent α phase and liquid is also presented by means of computer programming. Recursion method is adopted to calculate the electronic structure of RE (rare earth) in grains and around phase boundaries respectively. The calculation shows that RE is more stable around phase boundaries than in grains, which explains the fact that the solution of RE in α phase is less, and RE mainly aggregates in front of phase boundary. The calculations of bonding order integrals also show that RE in front of phases hardly solidify onto the grain surfaces as active element so as to prevent grains growth and refine the grains. As a result, the modification mechanism of RE may be explained from the view of electronic structure. | Guili LIU, Rongde LI and Zhenping ZHOUSchool of Materials Science and Engineering, Shenyang University of Technology, Shenyang 110023, China | 2004 | Journal of Materials Science & Technology2004，20，5： | 6 |
| 8 | Aerodynamic Optimum Design of Transonic Turbine Cascades Using Genetic Algorithms显示文摘This paper presents an aerodynamic optimum design method for transonic turbine cascades based on the Genetic Algorithms coupled to the inviscid flow Euler solver and the boundary-layer calculation.The Genetic Algorithms control the evolution of a population of cascades towards an optimum design.The fitness value of each string is evaluated using the flow solver. The design procedur6 has been developed and the behavior of the genetic algorithms has been tested. The objective functions of the design examples are the minimum mean-square deviation between the aimed pressure and computed pressure and the minimum amount of user expertise. | Li Jun Feng Zhenping Chang Jianzhong Shen Zuda(Institute of Turbomachinery, School of Energy & Power Engineering, Xi’an Jiaotong University,Xi’an, Shaanxi, 710049, China) | 1997 | Journal of Thermal Science1997，6，2： | 6 |
| 9 | Breast Cancer Screening Rates Among Women Aged 20 Years and Above—China,2015显示文摘What is already known about this topic?Breast cancer is the most common cancer in women in China and around the world.By 2019,121 countries have instituted a national screening program as a secondary prevention measure for breast cancer.What is added by this report?Breast cancer screening rates in China were 18.9%in women aged 20 years and above,and 25.7%in women aged 35-64 years in 2015.The screening rate for women aged 20 years and above was significantly higher in urban areas than in rural areas(24.6%vs.15.0%),and in the eastern region than in the central and western regions(24.0%vs.15.1%and 15.3%). | Mei Zhang Yijing Zhong Heling Bao Zhenping Zhao Zhengjing Huang Xiao Zhang Chun Li Maigeng Zhou Limin Wang Jing Wu Xiaoying Zheng Linhong Wang | 2021 | China CDC weekly2021，3，13： | 5 |
| 10 | Au plasmon enhanced high performance β-Ga_2O_3 solar-blind photo-detector显示文摘Surface plasmon polariton(SPP) is electro-magnetic wave coupled to free electron oscillations near the surface of metal, and has been used to improve the photoelectric properties in many optoelectronic devices. In the present study, the Au nanoparticles(NPs)/β-Ga_2O_3 composite thin film was fabricated through depositing Au ultra-thin film on the β-Ga_2O_3 thin film followed by post-thermal treatment. Compared to bare β-Ga_2O_3 thin film, a significant absorption around 510 nm, which is attributed to SPP of Au NPs, was observed in the UV–vis spectrum of Au NPs/β-Ga_2O_3 composite thin film. The results showed that the photoresponse of Au NPs/Ga_2O_3 photodetector illuminated under 254 nm +532 nm light was much higher than that illuminated under 254 nm light, indicating an enhancement of photoelectric property for the solar-blind photodetector based on β-Ga_2O_3 thin film. | Yuehua An Xulong Chu Yuanqi Huang Yusong Zhi Daoyou Guo Peigang Li Zhenping Wu Weihua Tang | 2016 | Progress in Natural Science:Materials International2016，26，1： | 5 |
| 11 | PK-tailored tertiary prophylaxis in patients with severe hemophilia A at beijing Children’s Hospital显示文摘Importance:Tertiary prophylaxis using a low-dose regimen is usually insufficient to prevent recurrent joint bleeding and deterioration in joint diseases in children with severe hemophilia A.Pharmacokinetic(PK)dosing is a useful approach to increase the precision and efficiency of prophylaxis.Objective:To explore the efficacy of PK-tailored tertiary prophylaxis in children with severe hemophilia A.Methods:We implemented a PK-tailored tertiary prophylaxis program for 15 boys with severe hemophilia A aged 5-16 years at Beijing Children’s Hospital.Following PK testing and a 6-month evaluation period(phase I),15 patients were divided in two groups according to individual PK data and actual bleeding:(1)a PK-tailored group[modified prophylaxis regimen according to PK data for the next 6 months(phase II);n=8]and(2)a maintenance group(continued the original regimen for the next 6 months;n=7).We compared the bleeding rate,infusion frequency,and factor VIII(FVIII)consumption between the two groups.results:In the PK-tailored group,the median annual joint bleeding rate was reduced from 7.8 in phase I to 1.4 in phase II,mean annual total factor consumption increased from 1619.0 IU/kg in phase I to 2401.9 IU/kg in phase II,and median infusion frequency for prophylaxis increased from 104 times/year in phase I to 156 times/year in phase II(P<0.05).Although the FVIII consumption increased,it remained at approximately half of the standard method.Interpretation:PK-tailored prophylaxis may represent a more efficient approach to individual prophylaxis in China,but further studies are required to verify this. | Peijing Li Zhenping Chen Xiaoling Cheng Yan Wang Ningning Zhang Yingzi Zhen Xinyi Wu Runhui Wu | 2019 | Pediatric Investigation2019，3，1： | 3 |
| 12 | Identification and molecular characterization of two novel mutations in COL1A2 in two Chinese families with osteogenesis imperfecta显示文摘成骨 imperfecta (OI,也已知的同样易碎的骨头疾病) 主要被变化在二种类型引起我编码类型的 pro-1 (I) 和 pro-2 (I) 链的骨胶原基因, COL1A1 和 COL1A2 我骨胶原分别地。有正染色体的主导的 OI 的二个中国家庭被识别并且描绘。连接分析在染色体 7q21.3-q22.1 上揭示了两个家庭的连接到 COL1A2。Mutational 分析用直接 DNA 顺序分析被执行。二个新奇错误感觉变化, c.3350A > G 和 c.3305G > C,在 exon 被识别在二个家庭的 49 COL1A2 分别地。c.3305G > C 变化在 codon 由丙氨酸残余(A) 导致了 glycine 残余(G) 的替换 1102 (p.G1102A ) ,它被发现在另外的家庭被变异进丝氨酸(S) , argine (R) ,丁氨二酸酸(D) ,或缬氨酸(V) 。c.3350A > G 变体可以是导致 p.Y1117C 的一个 de novo 变化。两个变化在各自的家庭与 OI 共同分离,并且没在 100 正常控制被发现。G1102 和 Y1117 残余高度 evolutionarily 从 zebrafish 被保存到人。Mutational 分析没在 COX-2 基因(OI 的修饰词基因) 识别任何变化。这研究识别引起 OI 的二新奇变化 p.G1102A 和 p.Y1117C,显著地扩展引起 OI 的 COL1A2 变化的光谱,并且有在 OI 的出生前的诊断的一个重要含意。 | Zhenping Xu Yulei Li Xiangyang Zhang Fanming Zeng Mingxiong Yuan Mugen Liu Qing Kenneth Wang Jing Yu Liu | 2011 | Journal of Genetics and Genomics2011，38，4： | 3 |
| 13 | Effect of age on the pharmacokinetics of polymorphic nimodipine in rats after oral administration显示文摘The previous investigation has proved that their existed pharmacokinetic difference between the different crystal forms of the polymorphic drugs after oral administration.However,no systemic investigations have been made on the change of this pharmacokinetic difference,resulted either from the physiological or from the pathological factors.In this paper,we used polymorphic nimodipine(Nim) as a model drug and investigated the effect of age difference(2- and 9-month old) on the pharmacokinetics after oral delivery in rats.As the results shown,for L-form of Nim(L-Nim),the AUC0–24 hin 2-month-old rats was 343.68747.15 ng h/m L,which is 23.36% higher than that in 9-month-old rats.For H-form of Nim(H-Nim),the AUC0–24 hin 2-monthold rats was 140.91719.47 ng h/m L,which is 54.64% higher than that in 9-month-old rats.The AUC0–24 h ratio between H-Nim and L-Nim was 2.44 in 2-month-old rats and 3.06 in 9-month-old rats.Since age difference could result in unparallelled change of the absorption and bioavailability of the polymorphic drugs,the results in this experiment are of value for further investigation of crystal form selection in clinical trials and rational clinical application of the polymorphic drugs. | Wenli Liu Xiaona Wang Ruilian Chen Kaixuan Zhang Yao Li Yi Li Duanyun Si Junbo Gong Dianshu Yin Yongli Wang Zhenping Wei Mingshi Yang | 2016 | Acta Pharmaceutica Sinica B2016，6，5： | 3 |
| 14 | Transonic flow of moist air around an NACA 0012 airfoil with non-equilibrium condensation显示文摘The classical condensation model of water vapor is coupled with the Euler equations to calculate transonic flows of moist air with non-equilibrium condensation. By means of this model, numerical computations are implemented to investigate the aerodynamic characteristics of an NACA 0012 airfoil in transonic flows of moist air at various angles of attack and relative humidities, and the results are compared with those in dry air flows. For different angles of attack considered at 50% relative humidity, the lift decreases 30%—40%. The pressure drag increases when the angle of attack is smaller than 1.4° and decreases when higher than 1.4°. At zero angle of attack, with the relative humidity rising from zero to 90%, the pressure drag increases exponentially. At 90% relative humidity, the pressure drag increases 160%, and self-oscillation takes place periodically and alternately over the upper and lower surfaces of the airfoil. The oscillation is caused by the interactions of local supersonic flow and heat release in the condensation process. | LI Liang SUN Xiuling FENG Zhenping LI Guojun | 2005 | Progress in Natural Science:Materials International2005，15，9： | 2 |
| 15 | Aerodynamic inverse design optimization for turbine cascades based on control theory显示文摘Based on control theory,adjoint system for the general problem of turbomachinery aerodynamic optimization was studied and developed in the present paper by using the variation technique in the grid node coordinates combined with Jacobian Matrics of flow fluxes.Then the adjoint system for aerodynamic design optimization of turbine cascade governed by compressible Navier-Stokes equations was derived in detail.With the purpose of saving computation resources,the mathematic method presented in this paper avoids the coordinate system transforming in the traditional derivation process of the adjoint system and makes the adjoint system much more sententious.Given the general expression of objective functions consisting of both boundary integral and field integral,the adjoint equations and their boundary conditions were derived,and the final expression of the objective function gradient including only boundary integrals was formulated to reduce the CPU cost,especially for the complex 3D configurations.The adjoint system was solved numerically by using the finite volume method with an explicit 5-step Runge-Kutta scheme and Riemann approximate solution of Roe's scheme combined with multi-grid technique and local time step to accelerate the convergence procedure.Finally,based on the aerodynamic optimization theory in the present work,2D and 3D inviscid and viscous inverse design programs of axial turbomachinery cascade for both pressure distribution and isentropic Mach number distribution on the blade wall were developed,and several design optimization cases were performed successfully to demonstrate the ability and economy of the present optimization system. | FENG ZhenPing LI HaiTao SONG LiMing LI YingChen | 2013 | Science China(Technological Sciences)2013，56，2： | 2 |
| 16 | A k-ε Turbulence Model Considering Compressibility in Three-Dimensional Transonic Turbulent Flow Calculation显示文摘Based on the standard k-ε turbulence model, a new compressible k-ε model considering the pressure expansion influence due to the compressibility of fluid is developed and applied to the simulation of 3D transonic turbulent flows in a nozzle and a cascade. The Reynolds avenged N-S equations in generalized curvilinear coordinates are solved with implementation of the new model. The high resolution TVD scheme is used to discretize the convective terms. The numerical results show that the compressible k-ε model behaves well in the simulation of transonic internal turbulent flows. | Guojun LI Zhenping FENG Moujin ZhANG Liang LI (School of Energy & Power Engineering, Xi’an Jiaotong University, Xi’an 710049, China) | 2000 | Journal of Thermal Science2000，9，2： | 2 |
| 17 | Strongly coupled Te-SnS_(2)/MXene superstructure with self-autoadjustable function for fast and stable potassium ion storage显示文摘Potassium-ion batteries(PIBs)are a promising candidate for next-generation electric energy storage applications because of the abundance and low cost of potassium.However,the development of PIBs is limited by sluggish kinetics and huge volume expansion of anodes,leading to poor rate capability and cycling stability.Herein,an advanced superstructure anode,including Te-doped SnS_(2) nanosheets uniformly anchored on MXene surface(Te-SnS_(2)/MXene),is rationally designed for the first time to boost K^(+)storage performance.Featuring with strong interface interaction and self-autoadjustable interlayer spacings,the Te-SnS_(2)/MXene can efficiently accelerate electron/ion transfer,accommodate volume expansion,inhibit crack formation,and improve pseudocapacitive contribution during cycling.Thus,the novel Te-SnS_(2)/MXene anode delivers a high reversible capacity(343.2 mAh g^(-1) after 50 cycles at0.2 A g^(-1)),outstanding rate capability(186.4 mAh g^(-1) at 20 A g^(-1)),long cycle stability(165.8 mAh g^(-1)after 5000 cycles at 10 A g^(-1) with a low electrode swelling rate of only 15.4%),and reliable operation in flexible full battery.The present Te-SnS_(2)/MXene becomes among the best transition metal-based anode materials for PIBs reported to date. | Hongyang Sun Yelong Zhang Xiaodan Xu Jianwen Zhou Fan Yang Hao Li Hao Chen Yucheng Chen Zheng Liu Zhenping Qiu Da Wang Lipo Ma Jiawei Wang Qingguang Zeng Zhangquan Peng | 2021 | Journal of Energy Chemistry2021，30，10： | 2 |
| 18 | Numerical investigation on the self-excited oscillation of wet steam flow in a supersonic turbine cascade显示文摘自我刺激的流动摆动在在湿蒸气汽轮机的冷凝作用过程期间由于特定的超级批评的热增加是一个重要问题。与一个 Eulerian/Eulerian 模型一起,在超声的汽轮机串联的湿蒸气流动的自我刺激的摆动被调查。合适的入口 supercooling 在蒸气汽轮机的串联从稳定的流动导致转变到自我刺激的震荡流动。入口 supercooling 上的频率相关性不是单音的补品。流动摆动导致入口和插头团流动率的异步的期刊变化。片上的空气动力学的力量由于自我刺激的流动摆动周期性地变化。与在 18.1-80-64 Hz 之间的频率谎言,震荡的流动是容易的在一个共振的模式由于定子转子相互作用与入口 supercooling 的期刊变化行动,并且在片上导致更大的空气动力学的力量。在震荡的流动的损失在稳定的流动与那相比增加 20.64% 。 | LI Liang SUN Xiuling LI Guojun FENG Zhenping | 2006 | Progress in Natural Science:Materials International2006，16，9： | 2 |
| 19 | Image Inpainting Based on Improved Deep Convolutional Auto-encoder Network显示文摘This paper proposes an effective image inpainting method using an improved deep convolutional auto-encoder network.By analogy with exiting methods of image inpainting based on auto-decoders,inpainting methods using the deep convolutional auto-encoder networks are significantly more effective in capturing high-level features than classical methods based on exemplar.However,the inpainted regions would appear blurry and global inconsistency.To alleviate the fuzzy problem,we improved the network model by adding skip connections between mirrored layers in encoder and decoder stacks,so that the generative process of the inpainting area can directly use the low-level features information of the processing image.For making the inpainted result look both more plausible and consistent with its surrounding contexts,the model is trained with a combination of standard pixel-wise reconstruction loss and two adversarial losses which ensures pixel-accurate and local-global contents consistency.With extensive experimental on the ImageNet and Paris Streetview datasets,we demonstrate qualitatively and quantitatively that our approach performs better than state of the art. | QIANG Zhenping HE Libo DAI Fei ZHANG Qinghui LI Junqiu | 2020 | Chinese Journal of Electronics2020，29，6： | 2 |
| 20 | Enhanced uptake and anti-maturation effect of celastrol-loaded mannosylated liposomes on dendritic cells for psoriasis treatment显示文摘Psoriasis is an autoimmune skin disease in which dendritic cells(DCs) trigger the progression of psoriasis by complex interactions with keratinocytes and other immune cells. In the present study,we aimed to load celastrol, an anti-inflammatory ingredient isolated from Chinese herbs, on mannosylated liposomes to enhance DC uptake as well as to induce DC tolerance in an imiquimod-induced psoriasis-like mouse model. Mannose was grafted onto liposomes to target mannose receptors on DCs. The results demonstrated that compared with unmodified liposomes, DCs preferred to take up more fluorescence-labeled mannosylated liposomes. After loading celastrol into mannose-modified liposomes,they effectively inhibited the expression of maturation markers, including CD80, CD86 and MHC-II, on DCs both in vitro and in vivo. Additionally, after intradermal injection with a microneedle, celastrolloaded mannose-modified liposomes(CEL-MAN-LPs) achieved a superior therapeutic effect compared with free drug and celastrol-loaded unmodified liposomes in the psoriasis mouse model in terms of the psoriasis area and severity index, histology evaluation, spleen weight, and expression of inflammatory cytokines. In conclusion, our results clearly revealed that CEL-MAN-LPs was an effective formulation for psoriasis treatment and suggested that this treatment has the potential to be applied to other inflammatory diseases triggered by activated DCs. | Long Xi Zibei Lin Fen Qiu Shaokui Chen Ping Li Xin Chen Zhenping Wang Ying Zheng | 2022 | Acta Pharmaceutica Sinica B2022，12，1： | 2 |
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