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| 1 | Co-author Weighting in Bibliometric Methodology and Subfields of a Scientific Discipline显示文摘Purpose: To give a theoretical framework to measure the relative impact of bibliometric methodology on the subfields of a scientific discipline, and how that impact depends on the method of evaluation used to credit individual scientists with citations and publications. The authors include a study of the discipline of physics to illustrate the method. Indicators are introduced to measure the proportion of a credit space awarded to a subfield or a set of authors.Design/methodology/approach: The theoretical methodology introduces the notion of credit spaces for a discipline. These quantify the total citation or publication credit accumulated by the scientists in the discipline. One can then examine how the credit is divided among the subfields. The design of the physics study uses the American Physical Society print journals to assign subdiscipline classifications to articles and gather citation, publication, and author information. Credit spaces for the collection of Physical Review Journal articles are computed as a proxy for physics.Findings: There is a substantial difference in the value or impact of a specific subfield depending on the credit system employed to credit individual authors.Research limitations: Subfield classification information is difficult to obtain. In the illustrative physics study, subfields are treated in groups designated by the Physical Review journals. While this collection of articles represents a broad part of the physics literature, it is not all the literature nor a random sample.Practical implications: The method of crediting individual scientists has consequences beyond the individual and affects the perceived impact of whole subfields and institutions. Originality/value: The article reveals the consequences of bibliometric methodology on subfields of a disciple by introducing a systematic theoretical framework for measuring the consequences. | Lawrence Smolinsky Aaron J Lercher | 2020 | Journal of Data and Information Science2020，5，3： | 3 |
| 2 | AIF-regulated oxidative phosphorylation supports lung cancer development显示文摘Cancer is a major and still increasing cause of death in humans. Most cancer cells have a fundamentally different metabolic profile from that of normal tissue. This shift away from mitochondrial ATP synthesis via oxidative phosphorylation towards a high rate of glycolysis, termed Warburg effect, has long been recognized as a paradigmatic hallmark of cancer, supporting the increased biosynthetic demands of tumor cells. Here we show that deletion of apoptosis-inducing factor (AIF) in a Kras^G12D-driven mouse lung cancer model resulted in a marked survival advantage, with delayed tumor onset and decreased malignant progression. Mechanistically, Aif deletion leads to oxidative phosphorylation (OXPHOS) deficiency and a switch in cellular metabolism towards glycolysis in non-transformed pneumocytes and at early stages of tumor development. Paradoxically, although Aif-deficient cells exhibited a metabolic Warburg profile, this bioenergetic change resulted in a growth disadvantage of Kras^G12D-driven as well as Kras wild-type lung cancer cells. Cell-autonomous re-expression of both wild-type and mutant AIF (displaying an intact mitochondrial, but abrogated apoptotic function) in Aif-knockout Kras^G12D mice restored OXPHOS and reduced animal survival to the same level as AIF wild-type mice. In patients with non-small cell lung cancer, high AIF expression was associated with poor prognosis. These data show that AIF-regulated mitochondrial respiration and OXPHOS drive the progression of lung cancer. | Shuan Rao Laura Mondragon Blanka Pranjic Toshikatsu Hanada Gautier Stoll Thomas Kocher Peng Zhang Alexander Jais Alexander Lercher Andreas Bergthaler Daniel Schramek Katharina Haigh Valentina Sica Marion Leduc Nazanine Modjtahedi Tsung-Pin Pai Masahiro Onji Iris Uribesalgo Reiko Hanada Ivona Kozieradzki Rubina Koglgruber Shane J. Cronin Zhigang She Franz Quehenberger Helmut Popper Lukas Kenner Jody J. Haigh Oliver Kepp Malgorzata Rak Kaican Cai Guido Kroemer Josef M. Penninger | 2019 | Cell Research2019，29，7： | 2 |
| 3 | The impact of cardiac natriuretic peptide determination on the dioagnosis and management of heart failure显示文摘 | Mair J Lercher A H Puschendort B | 2009 | Clin Chem Lab Med2009，39，7： | 1 |
| 4 | On the enhanced para-selectivity of HZSM-5 modified by antimony oxide显示文摘 | Shourong Zheng Andreas Jentys Johannes A Lercher | 2003 | J Catal2003，219，3： | 1 |
| 5 | Monomolecular conversion of light alkanes over H-ZSM-5 显示文摘 | Narbeshuber T F Vinek H Lercher J A | 1995 | Journal of Catalysis1995，157，： | 1 |
| 6 | Head - to - head comparson of N - terminal pro - brain natriuretic peptide, brain natriuretic peptid and N - terminal pro - brain natriurefic peptide in diagnosing left ventricul dysfunction 显示文摘 | Hammerer - lercher A Neubauer E Muller S | 2001 | Clin Chim Acta2001，310，： | 1 |
| 7 | Cardiac troponin and 13-type myosin heavy chain concentrations in patients with polymyositis or demm/omyositis 显示文摘 | Erlacher P Lercher A Falkensammer J | 2001 | Clin Chim Aeta2001，306，： | 1 |
| 8 | Head - to - head comparison of N - terminal pro - brain natriuretic peptide, brain natriuretic peptide and N - terminal pro- atrial natriuretic peptide in diagnosing left ventricular dysfunction显示文摘 | Hammerer - Lercher A Neubauer E Muller S | 2001 | Clin Chim Acta2001，310，2： | 1 |
| 9 | Sulfur-tolerant Pt-supported zeolite catalysts for benzene hydrogenation:Ⅰ Influence of the support显示文摘 | SIMON L J van OMMEN J G JENTYS A LERCHER J A | 2001 | J Catal2001，201，1： | 1 |
| 10 | Synthesis of new MCM-36 derivatives pillared with alumina or magnesia-alumina显示文摘 | BARTH J O KORNATOWSKI J LERCHER J A | 2002 | J Mater Chem2002，12，： | 1 |
| 11 | Design of stable catalysts for methane-carbon dioxide reforming显示文摘 | Lercher J A Bitter J H Hally W | 1996 | Studies in Surface Science and Catalysis1996，101，1： | 1 |
| 12 | Impact of forming and modification with phosphoric acid on theacid sites ofHZSM-5显示文摘 | XUE N OLINDO R LERCHER J A | 2010 | JPhys Chem C2010，114，15： | 1 |
| 13 | Bimetallic Pt–Pd/silica–alumina hydrotreating catalysts. Part II: Structure–activity correlations in the hydrogenation of tetralin in the presence of dibenzothiophene and quinoline显示文摘 | Yanzhe Yu Benjamin Fonfé Andreas Jentys Gary L. Haller J.A. Rob van Veen Oliver Y. Gutiérrez Johannes A. Lercher | 2012 | Journal of Catalysis2012，，： | 1 |
| 14 | Direct conversion of n-butane to isobutene over Pt-MCM-22显示文摘 | SESHAN K LERCHER J A | 2000 | J Catal2000，190，： | 1 |
| 15 | Mono and bifunctional pathways of CO2 CH4 reforming over Pt and Rh based catalysts显示文摘 | BITTER J H SESHAN K LERCHER J A | 1998 | J Catal1998，176，1： | 1 |
| 16 | The impact of cardiac natriuretic peptide determination on the diagnosis and management of heart failure显示文摘 | Mair J Lercher AH Puschendort B | 2001 | Clin Chem Lab Med2001，39，7： | 1 |
| 17 | ApplCatal显示文摘 | Lercher J A | 1986 | 25(1-2):215-2221986，25，12： | 1 |
| 18 | Cardiac troponin and beta-type myosin heavy chain concentrations in patients with polymyositis or dermatomysitis显示文摘 | Erlacher P Lercher A Falkensammer J | 2001 | Clin Chim Acta2001，306，12： | 1 |
| 19 | Dealumination of HZSM-5 via steam-treatment 显示文摘 | ONG L H DOMOK M OLINDO R VAN VEEN A C LERCHER J A | 2012 | Micropor Mesopor mater2012，164，： | 1 |
| 20 | Mouse model of myocardial remodelling after ischemia:role of intercellular adhesion molecule-1显示文摘 | Metzler B Mair J Lercher A | 2001 | Cardiovasc Res2001，49，2： | 1 |
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