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| 1 | 通过手机进行健康干预报告的指南:移动医疗证据报告和评估检查表显示文摘为提升移动医疗(mHealfh)干预报告的完整性,WH0mHealth技术证据评审小组开发了mHealth证据报告和评估(mERA)检查表。该mERA开发过程包括成立专家组,提出合适的路径,召集全球专家评审小组以研发检查表,并进行小规模测试。制定这些标准的指导原则是以最少的信息集合来定义mHealth干预是什么(内容),在哪儿应用(环境),如何应用(技术特性),以便支持干预的可重复性。该文档由16个选项表构成,附带各项内容的详细解释和说明,以及说明性的报告范例。通过广泛征求意见,我们希望该指南的应用可规范mHealth证据报告的质量,间接提升mHealth证据的质量。 | Smisha Agarwal Amnesty E LeFevre Jaime Lee Kelly L'Engle Garrett Mehl Chaitali Sinha Alain Labriquel 沈锡宾(译) 涂宏钢(校) | 2016 | 英国医学杂志中文版2016，19，11： | 6 |
| 2 | Tumor cells educate mesenchymal stromal cells to release chemoprotective and immunomodulatory factors显示文摘Factors released by surrounding cells such as cancer-associated mesenchymal stromal cells(CA-MSCs)are involved in tumor progression and chemoresistance.In this study,we characterize the mechanisms by which naYve mesenchymal stromal cells(MSCs)can acquire a CA-MSCs phenotype.Ovarian tumor cells trigger the transformation of MSCs to CA-MSCs by expressing pro-tumoral genes implicated in the chemoresistance of cancer cells,resulting in the secretion of high levels of CXC chemokine receptors 1 and 2(CXCR1/2)ligands such as chemokine(C-X-C motif)ligand 1(CXCL1),CXCL2,and interleukin 8(IL-8).CXCR1/2 ligands can also inhibit the immune response against ovarian tumor cells.Indeed,through their released factors,CA-MSCs promote the differentiation of monocytes towards M2 macrophages,which favors tumor progression.When CXCR1/2 receptors are inhibited,these CA-MSC-activated macrophages lose their M2 properties and acquire an anti-tumoral phenotype.Both ex vivo and in vivo,we used a CXCR1/2 inhibitor to sensitize ovarian tumor cells to carboplatin and circumvent the pro-tumoral effects of CA-MSCs.Since high concentrations of CXCR1/2 ligands in patients*blood are associated with chemoresistance,CXCR1/2 inhibition could be a potential therapeutic strategy to revert carboplatin resistance. | Augustin Le Naour Melissa Prat Benolt Thibault Renaud Mével Léa Lemaitre Helene Leray Marie-Veronique Joubert Kimberley Coulson Muriel Golzio Lise Lefevre Eliane Mery Alejandra Martinez Gwénael Ferron Jean-Pierre Delord Agnès Coste Bettina Couderc | 2020 | Journal of Molecular Cell Biology2020，12，3： | 3 |
| 3 | Some new classes of stochastic order relations among arithmetic random variables with applica-tions in actuarial sciences 显示文摘 | DENUIT M LEFEVRE C L | 1997 | Insurance:Mathematics and Economics1997，20，3： | 1 |
| 4 | Oral insulin administration and residual β-cell function in recent-onset type 1 diabetes:a multicentre randomized controlled trial显示文摘 | CHAILLOUS L LEFEVRE H THIVOLET C | 2000 | The Lancet2000，356，： | 1 |
| 5 | On s-convex stochastic extrema for arithmetic risks显示文摘 | DENUIT M LEFEVRE C L MESFIOUI M | 1999 | Insurance:Mathematics and Economics1999，25，2： | 1 |
| 6 | Determination of d and q reactance of permanent-magnet synchronous motors without measurements of the rotor position显示文摘 | Nee H P Lefevre L | 2000 | IEEE Transactions on Industry Applications2000，36，5： | 1 |
| 7 | How to assess physical activity? How to assess physical fit- ness?显示文摘 | Vanhees L Lefevre J Philippaerts R | 2005 | Journal of Cardiovascular Risk2005，12，2： | 1 |
| 8 | Stochastic orderings of convex/concave type on an arbitrary grid显示文摘 | DENU1T M LEFEVRE C L UTEV S | 1999 | Mathematics of Operations Research1999，24，4： | 1 |
| 9 | The s-convex orders among real random variables with applications 显示文摘 | DENUIT M LEFEVRE C L SHAKED M | 1998 | Mathe-matical Inequalities and Applications1998，1，4： | 1 |
| 10 | 显示文摘 | Cohen-Adad M T Lefevre A Cataldo L | 1996 | J Alloys and Comp1996，241，： | 1 |
| 11 | Production, purification and biological properties of an Escherichia coli-derived recombinant porcine alpha interferon显示文摘 | Lefevre F L' Haridon R Borras-Cuesta F | 1990 | J Gen Virol1990，71，5： | 1 |
| 12 | Relationship of obesity with physical activity, aerobic fitness and muscle strength in Flemish adults显示文摘 | Duvigneaud N Matton L Wijndaele K Deriemaeker P Lefevre J Philippaerts R Thomis M Delecluse C Duquet W | 2008 | Journal of Sports Medicine and Physical Fitness2008，，2： | 1 |
| 13 | Reappraisal of metastatic lymph node topography in head and neck squamous cell carcinomas显示文摘 | Tao L Lefevre M Callard P | 2006 | Otolaryngol Head Neck Surg2006，135，3： | 1 |
| 14 | Insulin regu- lates milk protein synthesis at multiple levels in the bovine mammary gland 显示文摘 | Menzies K K Lefevre C Macmillan K L | 2009 | Funct Integr Genomics2009，9，2： | 1 |
| 15 | PPARγ, ligands switched high fat diet-induced macrophage M2b polarization toward M2a thereby improving intestinal Candida elimination 显示文摘 | Lefevre L Gales A Olagnier D | 2010 | PLoS One2010，5，9： | 1 |
| 16 | Reoperative surgery for thyroid disease 显示文摘 | Lefevre J H Tresallet C Leenhardt L | 2007 | Langenbeck''s archives of surgery/ Deutsche Gesellschaft fur Chirnrgie2007，392，6： | 1 |
| 17 | Bacterial inoculum enhances keratin degradation and biofilm formation in poultry compost显示文摘 | Ichida J M Krizova L LeFevre C A | 2001 | Journal of Microbiological Methods2001，47，2： | 1 |
| 18 | A Survey on Techniques for Improving the Energy Efficiency of Large Scale Distributed Systems显示文摘 | Orgerie A-C Assuncao M Lefevre L | 2014 | ACM Computing Surveys2014，46，4： | 1 |
| 19 | Activation of protein kinase A during human sperm capacitation and acrosome reaction显示文摘 | LEFEVRE L JHA K N DE LAMIRANDE E | 2002 | J Androl2002，23，5： | 1 |
| 20 | A Preliminary Report upon Some Halophilic Bacteria显示文摘 | ROUND L A | 1919 | Bacteriol1919，4，： | 1 |
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