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| 1 | Evolving role of FDG-PET/CT in prognostic evaluation of resectable gastric cancer显示文摘Gastric cancer(GC) remains a leading cause of cancer death worldwide. Radical gastrectomy is the only potentially curative treatment, and perioperative adjuvant therapies may improve the prognosis after curative resection. Prognosis largely depends on the tumour stage and histology, but the host systemic inflammatory response(SIR) to GC may contribute as well, as has been determined for other malignancies. In GC patients, the potential utility of positron emission tomography/computed tomography(PET/CT) with the imaging radiopharmaceutical 18F-fluorodeoxyglucose(FDG) is still debated, due to its lower sensitivity in diagnosing and staging GC compared to other imaging modalities. There is, however, growing evidence that FDG uptake in the primary tumour and regional lymph nodes may be efficient for predicting prognosis of resected patients and for monitoring tumour response to perioperative treatments, having prognostic value in that it can change therapeutic strategies. Moreover, FDG uptake in bone marrow seems to be significantly associated with SIR to GC and to represent an efficient prognostic factor after curative surgery. In conclusion, PET/CT technology is efficient in GC patients, since it is useful to integrate other imaging modalities in staging tumours and may have prognostic value that can change therapeutic strategies. With ongoing improvements, PET/CT imaging may gain further importance in the management of GC patients. | Emilio De Raffele Mariateresa Mirarchi Dajana Cuicchi Ferdinando Lecce Bruno Cola | 2017 | World Journal of Gastroenterology2017，23，38： | 5 |
| 2 | Simultaneous curative resection of double colorectal carcinoma with synchronous bilobar liver metastases显示文摘Synchronous colorectal carcinoma(SCRC) indicates more than one primary colorectal carcinoma(CRC) discovered at the time of initial presentation, accounts for 3.1%-3.9% of CRC, and may occur either in the same or in different colorectal segments. The accurate preoperative diagnosis of SCRC is difficult and diagnostic failures may lead to inappropriate treatment and poorer prognosis. SCRC requires colorectal resections tailored to individual patients, based on the number, location, and stage of the tumours, from conventional or extended hemicolectomies to total colectomy or proctocolectomy, when established predisposing conditions exist. The overall perioperative risks of surgery for SCRC seem to be higher than for solitary CRC. Simultaneous colorectal and liver resection represents an appealing surgical strategy in selected patients with CRC and synchronous liver metastases(CRLM), even though the cumulative risks of the two procedures need to be adequately evaluated. Simultaneous resections have the noticeable advantage of avoiding a second laparotomy, give the opportunity of an earlier initiation of adjuvant therapy, and may significantly reduce the hospital costs. Because an increasing number of recent studies have shown goodresults, with morbidity, perioperative hospitalization, and mortality rates comparable to staged resections, simultaneous procedures can be selectively proposed even in case of complex colorectal resections, including those for SCRC and rectal cancer. However, in patients with multiple bilobar CRLM, major hepatectomies performed simultaneously with colorectal resection have been associated with significant perioperative risks. Conservative or parenchymal-sparing hepatectomies reduce the extent of hepatectomy while preserving oncological radicality, and may represent the best option for selected patients with multiple CRLM involving both liver lobes. Parenchymal-sparing liver resection, instead of major or two-stage hepatectomy for bilobar disease, seemingly reduces the overall operative risk of candidates to simultaneous colorectal and liver resection, and may represent the most appropriate surgical strategy whenever possible, also for patients with advanced SCRC and multiple bilobar liver metastases. | Emilio De Raffele Mariateresa Mirarchi Dajana Cuicchi Ferdinando Lecce Claudio Ricci Riccardo Casadei Bruno Cola Francesco Minni | 2018 | World Journal of Gastrointestinal Oncology2018，10，10： | 3 |
| 3 | Simultaneous colorectal and parenchymal-sparing liver resection for advanced colorectal carcinoma with synchronous liver metastases:Between conventional and mini-invasive approaches显示文摘The optimal timing of surgery in case of synchronous presentation of colorectal cancer and liver metastases is still under debate.Staged approach,with initial colorectal resection followed by liver resection(LR),or even the reverse,liver-first approach in specific situations,is traditionally preferred.Simultaneous resections,however,represent an appealing strategy,because may have perioperative risks comparable to staged resections in appropriately selected patients,while avoiding a second surgical procedure.In patients with larger or multiple synchronous presentation of colorectal cancer and liver metastases,simultaneous major hepatectomies may determine worse perioperative outcomes,so that parenchymal-sparing LR should represent the most appropriate option whenever feasible.Mini-invasive colorectal surgery has experienced rapid spread in the last decades,while laparoscopic LR has progressed much slower,and is usually reserved for limited tumours in favourable locations.Moreover,mini-invasive parenchymal-sparing LR is more complex,especially for larger or multiple tumours in difficult locations.It remains to be established if simultaneous resections are presently feasible with mini-invasive approaches or if we need further technological advances and surgical expertise,at least for more complex procedures.This review aims to critically analyze the current status and future perspectives of simultaneous resections,and the present role of the available miniinvasive techniques. | Emilio De Raffele Mariateresa Mirarchi Dajana Cuicchi Ferdinando Lecce Riccardo Casadei Claudio Ricci Saverio Selva Francesco Minni | 2020 | World Journal of Gastroenterology2020，26，42： | 3 |
| 4 | β(1)andβ(3)integrinsdisassemble from basal focal adhesions andβ(3)integrin is laterlocalised to the apical plasma membrane of rat uterine luminalepithelial cells at the time of implantation显示文摘 | Kaneko Y Lecce L Day ML | 2011 | Reprod Fertil2011，23，3： | 1 |
| 5 | Longitudinal effects of theory of mind on later peer relations: The role of prosocial behavior 显示文摘 | Caputi M Lecce S Pagnin A | 2012 | Developmental Psychology2012，48，1： | 1 |
| 6 | Nutrition and management of early weaned piglets: liquid vs dry feeding显示文摘 | LECCE J G ARMSTRONG W D CRAWFORD P C | 1979 | J Anim Sci1979，48，5： | 1 |
| 7 | Sensonality of flooding in North Carolina显示文摘 | Lecce S A | 2000 | Southeastem Geographer2000，41，2： | 1 |
| 8 | A novel SMA-based concept for airfoil structural mor- phing显示文摘 | BARBARINO S PECORA R LECCE L | 2009 | Journal of Material Engineering and Per- formance2009，696，18： | 1 |
| 9 | An evaluation of the effectiveness of image features for image retrieval显示文摘 | V Di Lecce A Guerriero | 1999 | J Visual Comm Image Representation1999，10，4： | 1 |
| 10 | 'Mapping the Wolf- Hirschhorn syndrome phenotype outside the currently accepted WHS critical region and defining a new critical region, WHSCR- 2' 显示文摘 | M Zollino R Lecce R Fischetto | 2003 | American Journal of Human Genetics2003，72，3： | 1 |
| 11 | Presence of estrogen receptor beta in the human endometrium through the cycle: expression in glandular,stromal, and vascular cells显示文摘 | Lecce G Meduri G Ancelin M | 2001 | Clin Endocrinol Metab2001，86，3： | 1 |
| 12 | LC–MS Determination of remifentanil in maternal and neonatal plasma显示文摘 | Elena Bossù Annalisa Montinaro Raffaele Lecce Anna Farina Ennia Suppa Gaetano Draisci Gianluca Gostoli | 2006 | Journal of Pharmaceutical and Biomedical Analysis2006，，3： | 1 |
| 13 | Focal adhesion kinase localizesto sites of cell-to-cell contact in vivo and increases apically in rat uter-ine luminal epithelium and the blastocyst at the time of implantation显示文摘 | Kaneko Y Lecce L Day M L | 2012 | J Morphol2012，273，6： | 1 |
| 14 | The direct strength method for stainless steel compression members显示文摘 | Jurgen Becque Maura Lecce Kim J.R. Rasmussen | 2008 | Journal of Constructional Steel Research2008，，11： | 1 |
| 15 | Spinal giant cell tumor in tuberous sclerosis : case report and review of the literature 显示文摘 | Fraioli MF Lecce M Fraioli C | 2013 | J Spinal Cord Med2013，36，： | 1 |
| 16 | Atypical maternal behavior toward feeding-disordered infants before and after intervention显示文摘 | Benoit D Madigan S Lecce S | 2001 | Infant Mental Health Journal2001，22，6： | 1 |
| 17 | Fuzzy Clustering With Partial Supervision in Organization and Classification of Digital Images显示文摘 | Pedrycz W Amato A Di Lecce V | 2008 | IEEE Transactions on Fuzzy Systems2008，16，4： | 1 |
| 18 | Rotavirus and hemolytic enteropathogenic Escherichia coli in weanling diarrhea of pigs 显示文摘 | Lecce J G Balsbaugh R K Clare D A et d | 1982 | J Clin Microbiol1982，16，： | 1 |
| 19 | Short-sales constraints and market quality: Evidence from the 2008 short-sales bans显示文摘 | Alex Frino Steven Lecce Andrew Lepone | 2011 | International Review of Financial Analysis2011，，4： | 1 |
| 20 | Characterization of olive mill wastewater fractions treatment by integrated membrane pro- cess显示文摘 | Di Lecce G Cassano A Bendini A | 2014 | Journal of the Science of Food and Agriculture2014，94，： | 1 |
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