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| 1 | The stress corrosion susceptibility of aluminium alloy 7020 welded sheets显示文摘 | Reboul M C Dubost B Lashermes M | 1985 | Corrosion Science1985，25，11： | 1 |
| 2 | Sorption and mineralization of organic pollutants during different stages of compos- ting 显示文摘 | Lashermes G Houot S Barriuso E | 2010 | Chemosphere2010，79，4： | 1 |
| 3 | A new equation to simulate the contact between soil and maize residues of different sizes during their decomposition显示文摘 | Akhtar Iqbal Patricia Garnier Gwena?lle Lashermes Sylvie Recous | 2014 | Biology and Fertility of Soils2014，，4： | 1 |
| 4 | Involvement of toll-like receptor 5 in mouse model of colonic hypersensitivity induced by neonatal maternal separation显示文摘BACKGROUND Chronic abdominal pain is the most common cause for gastroenterology consultation and is frequently associated with functional gastrointestinal disorders including irritable bowel syndrome and inflammatory bowel disease. These disorders present similar brain/gut/microbiota trialogue alterations, associated with abnormal intestinal permeability, intestinal dysbiosis and colonic hypersensitivity(CHS). Intestinal dysbiosis can alter colon homeostasis leading to abnormal activation of the innate immunity that promotes CHS, perhaps involving the toll-like receptors(TLRs), which play a central role in innate immunity.AIM To understand the mechanisms between early life event paradigm on intestinal permeability, fecal microbiota composition and CHS development in mice with TLRs expression in colonocytes.METHODS Maternal separation model(NMS) CHS model, which mimics deleterious events in childhood that can induce a wide range of chronic disorders during adulthood were used. Colonic sensitivity of NMS mice was evaluated by colorectal distension(CRD) coupled with intracolonic pressure variation(IPV) measurement. Fecal microbiota composition was analyzed by 16S rRNA sequencing from weaning to CRD periods. TLR mRNA expression was evaluated in colonocytes.Additionally, the effect of acute intrarectal instillation of the TLR5 agonist flagellin(FliC) on CHS in adult naive wildtype mice was analyzed.RESULTS Around 50% of NMS mice exhibited increased intestinal permeability and CHS associated with intestinal dysbiosis, characterized by a significant decrease of species richness, an alteration of the core fecal microbiota and a specific increased relative abundance of flagellated bacteria. Only TLR5mRNA expression was increased in colonocytes of NMS mice with CHS. Acute intrarectal instillation of FliC induced transient increase of IPV, reflecting transient CHS appearance.CONCLUSION Altogether, these data suggest a pathophysiological continuum between intestinal dysbiosis and CHS, with a role for TLR5. | Geoffroy Mallaret Amandine Lashermes Mathieu Meleine Ludivine Boudieu Julie Barbier Youssef Aissouni Agathe Gelot Benoit Chassaing Andrew T Gewirtz Denis Ardid Frederic Antonio Carvalho | 2022 | World Journal of Gastroenterology2022，28，29： | 1 |
| 5 | Genetic control of ma- ternal haploid in maize and selection of haploid lines显示文摘 | LASHERMES P BECKERT M | 1988 | Theor Appl Genet1988，76，： | 1 |
| 6 | Use of random amplified DNA markers to analyse genetic variability and relationships of Coffeaspecies显示文摘 | Lashermes P Cros J Marmey P | 1993 | Genetic Resources and Crop Evolution1993，40，2： | 1 |
| 7 | Inheritance and restriction fragment length polymorphism of chloroplast DNA in the genusCoffea L显示文摘 | Lashermes P Curs J Combes M C | 1996 | TAG Theoretical and Applied Genetics1996，93，4： | 1 |
| 8 | Genetic control of maternal haploidy in maize and selection of haploid inducing lines显示文摘 | LASHERMES P BECKERT M | 1988 | Theoretical and applied genetics1988，76，3： | 1 |
| 9 | Genetic diversity for RAPD markers between cultivated and wild accessions of Coffea arabica显示文摘 | Lashermes P Trouslot P Anthony F | 1996 | Euphytica1996，87，1： | 1 |
| 10 | Genetic linkage map of Coffeacanephora: Effect of segregation distortion and analysis of recombination rate in male and female meiosis显示文摘 | Lashermes P Combes M C Prasash N S | 2001 | Genome2001，44，4： | 1 |
| 11 | Gynogenetic haploid plants analysis for agronomic and enzymatic markers in maize (Zea mays L.)显示文摘 | P. Lashermes A. Gaillard M. Beckert | 1988 | Theoretical and Applied Genetics1988，，4： | 1 |
| 12 | Iden- tification of RAPD markers for resistance to cof- fee berry disease,Colletotrichum kahawae,in ara- bica coffee显示文摘 | Agwanda C 0 Lashermes P Trouslot P | 1997 | Euphytica1997，97，2： | 1 |
| 13 | Construction of a molecular linkage map in coffee显示文摘 | Paillard M Lashermes P Petiard V | 1996 | TAG Theoretical and Applied Genetics1996，93，1： | 1 |
| 14 | Sorption and mineralization of organic pollutants during different stages of composting 显示文摘 | Lashermes G Houot S Barriuso E | 2010 | Chemosphere2010，79，： | 1 |
| 15 | Cannear-infrared reflectance of green coffee be used to detect introgression in coffea arabica cultivars显示文摘 | Bertrand B Etienne H Lashermes P | | 0，，06： | 1 |
| 16 | genome显示文摘 | Lashermes P Combes M C Robert J Molecular characterisation and origin of the Coffea arabica L | 1999 | Mol Gen Genet1999，261，： | 1 |
| 17 | Identification of RAPD markers for resistance to coffee berry disease,Colletotrichumkahawae,in aabica coffee显示文摘 | Agwanda C 0 Lashermes P Trouslot P | 1997 | Euphytica1997，97，2： | 1 |
| 18 | Genetic linkage map of Coffea canephora : Effect of segregation distortion and analysis of recombination rate in male and female meiosis 显示文摘 | Lashermes P Combes M C Prakash N S | 2001 | Genome2001，44，4： | 1 |
| 19 | Inheritance and genetic mapping of self-incompatibility in Coffea canephora Pierre显示文摘 | Lashermes P Couturon E Moreau N | 1996 | TAGTheoretical and Applied Genetics1996，93，3： | 1 |
| 20 | Composting in small laboratory pilots: Performance and reproducibility 显示文摘 | Lashermes G Barriuso E Le V P M | 2012 | Waste Manage2012，32，2： | 1 |
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