6篇
您的检索式：作者名="Lars Backer"
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| 1 | 2017欧洲心脏病学会/欧洲心胸外科协会心脏瓣膜病管理指南中经导管主动脉瓣置换术相关更新解读显示文摘自2012欧洲心脏协会/欧洲心胸外科协会关于心脏瓣膜病的管理指南发布以来,新的临床证据又大量积累。这些新证据使欧洲心脏协会/欧洲心胸外科协会需要更新瓣膜病的管理指南以达到心内科与心外科医师间的共识。该文将从经导管主动脉瓣置换术出发,解读2017年新指南所作出的更新。 | Tasalak Thonghong Manik Chopra Ole De Backer Lars Sndergaard 王玺 | 2018 | 华西医学2018，33，2： | 12 |
| 2 | Grid data and area delimitation by definition towards a better European territorial statistical system 显示文摘 | Marja Tammilehto-Luode Lars Backer | 2000 | Statistical journal of the United Nations ECE2000，，17： | 1 |
| 3 | Genetic and environmental contributions to hay fever among young adult twins显示文摘 | Simon Francis Thomsen Charlotte Suppli Ulrik Kirsten Ohm Kyvik Jacob von Bornemann Hjelmborg Lars Rauff Skadhauge Ida Steffensen Vibeke Backer | 2006 | Respiratory Medicine2006，，12： | 1 |
| 4 | Inflammatory Subtypes in Asthma are Related to Airway Hyperresponsiveness to Mannitol and Exhaled NO显示文摘 | Celeste Porsbjerg Thomas Kromann Lund Lars Pedersen Vibeke Backer | 2009 | Journal of Asthma2009，，6： | 1 |
| 5 | Grid data and area delimitation by definition towards a better European territorial statistical system 显示文摘 | Marja Tammilehto-Luode and Lars Backer | 2000 | Statistical journal of the United Nations ECE2000，，17： | 1 |
| 6 | Clinical valve thrombosis and subclinical leaflet thrombosis in transcatheter aortic heart valves:clinical manifestations,diagnosis,and treatment显示文摘During the last decade,transcatheter aortic valve replacement(TAVR)has rapidly expanded as an alternative to surgical aortic valve replacement(SAVR)in patients with symptomatic severe aortic valve stenosis(AS)and increased surgical risk.In TAVR,a bioprosthetic valve is positioned within the stenotic native aortic valve.Although favorable short-and medium-term outcomes have been reported,thrombosis of the transcatheter heart valve(THV)has occurred,with two different entities being described:clinical valve thrombosis and subclinical leaflet thrombosis.In clinical valve thrombosis,an increase in transvalvular gradient appears as a result of obstructive thrombus formation,which eventually leads to symptoms of heart failure.Subclinical leaflet thrombosis is an incidental finding,characterized by a thin layer of thrombus covering the aortic site of the leaflet—called hypoattenuating leaflet thickening(HALT)—as described on and defined by 4-dimensional computed tomography(4DCT)imaging.This phenomenon may affect motion of the leaflets and is then classified as hypo-attenuation affecting motion(HAM).Even in the case of HAM,the transvalvular pressure gradient remains within the normal range.Clinical valve thrombosis requires treatment,whereas the clinical impact and need for intervention in subclinical leaflet thrombosis is uncertain.Anticoagulant therapy protects against and resolves both clinical valve thrombosis and subclinical leaflet thrombosis,but studies exploring different antithrombotic strategies after TAVR are ongoing.This review summarizes currently available literature within the field of THV thrombosis and provides recommendations for a patient-tailored approach in TAVR patients,although guidelines are still lacking. | Liesbeth Rosseel Ole De Backer Lars Søndergaard | 2018 | Precision Clinical Medicine2018，1，3： | 0 |
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