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| 1 | The Stripe Rust Resistance Gene Yr10 Encodes an Evolutionary-Conserved and Unique CC-NBS-LRR Sequence in Wheat显示文摘对用一条基于地图的克隆途径从摩洛人小麦(Triticum aestivum L.) 孤立的条纹锈的第一棵幼苗或所有阶段抵抗(R) R 基因作为 Yr10 被识别。这基因的克隆 4B 编码一高度,进化保存和唯一的 CCNBSLRR 定序。克隆 4E, Yr10 的一个相当或相同的事物,而是缺乏的抄写开始地点(TSS ) 和通常认为的 TATA 盒子和 CAAT 盒子,是可能的非表示的 pseudogene。克隆 4B 和 4E 是 84% 在 intron 和 LRR 领域相同、分叉。基因 silencing 和 transgenesis 与无毒害、剧毒的条纹锈尽力表明 Yr10 功能的差别与接种一起被使用。Yr10 CCNBSLRR 顺序在在小麦的已知的 CCNBSLRR R 基因之中是唯一的,但是高度保存相当或相同的事物(E = 0.0 ) 包括 Hordeum vulgare 和 Brachypodium distachyon 在 Aegilops tauschii 和另外的 monocots 被识别。相关序列也在玉米的 genomic 数据库被识别,米饭,并且在里面蜀黍。这是在有在它的本国的主人的有限相同,但是与在为条纹锈是主人或非主人的相关 monocots 的众多的相应 R 基因的植物的 CCNBSLRR 抵抗基因的第一份报告。这些结果越过种类代表基因进化和分散的一个唯一的例子。 | Wei Liu Michele Frick Rene Huel Cory L. Nykiforuk Xiaomin Wang Denis A. Gaudet Francois Eudes Robert L. Conner Alan Kuzyk Zhensheng Kang Andre Laroche | 2014 | Molecular Plant2014，7，12： | 21 |
| 2 | A review of UHMWPE wear-induced osteolysis:the role for early detection of the immune response显示文摘In a world where increasing joint arthroplasties are being performed on increasingly younger patients,osteolysis as the leading cause of failure after total joint arthroplasty(TJA) has gained considerable attention.Ultra-high molecular weight polyethylene wear-induced osteolysis is the process by which prosthetic debris mechanically released from the surface of prosthetic joints induces an immune response that favors bone catabolism, resulting in loosening of prostheses with eventual failure or fracture. The immune response initiated is innate in that it is nonspecific and self-propagating, with monocytic cells and osteoclasts being the main effectors. To date, detecting disease early enough to implement effective intervention without unwanted systemic side effects has been a major barrier. These barriers can be overcome using newer in vivo imaging techniques and modules linked with fluorescence and/or chemotherapies. We discuss the pathogenesis of osteolysis, and provide discussion of the challenges with imaging and therapeutics. We describe a positron emission tomography imaging cinnamoyl-Phe-(D)-Leu-Phe-(D)-Leu-Phe-Lys module,specific to macrophages, which holds promise in early detection of disease and localization of treatment.Further research and increased collaboration among therapeutic and three-dimensional imaging researchers are essential in realizing a solution to clinical osteolysis in TJA. | Adrese M Kandahari Xinlin Yang Kevin A Laroche Abhijit S Dighe Dongfeng Pan Quanjun Cui | 2016 | Bone Research2016，4，2： | 7 |
| 3 | 利用减法AFLP有效标记小麦中的外源染色体片段(英文)显示文摘为解决AFLP中样品间共同片段对多态性片段识别的干扰 ,作者建立了一种“减法AFLP”标记技术 ,并运用这种技术成功对小麦中的外源染色体片段进行了标记。运用该技术 ,样品间的共同扩增片段显著减少 ,在非变性聚丙稀酰胺凝胶上带型差异十分明显 ,多态性片段很容易分辨。其真实性通过将其中两条成功转换成外源染色体片段特异的SCAR标记得到了验证。减法AFLP标记技术的建立为标记作物中的外源染色体片段提供了一种有效手段。 | 柴建芳 吴志明 赵和 Andre LAROCHE 王海波 | 2003 | Acta Botanica Sinica2003，45，4： | 7 |
| 4 | Starch Synthesis and Programmed Cell Death during Endosperm Development in Triticale(× Triticosecale Wittmack)显示文摘Triticale(× Triticosecale Wittmack) grains synthesize and accumulate starch as their main energy source.Starch accumulation rate and synthesis activities of ADP-glucose pyrophosphorylase,soluble starch synthases,granule-bound starch synthase and starch-branching enzyme showed similar pattern of unimodal curves during endosperm development.There was no significant difference in activity of the starch granule-bound protein isolated from total and separated starch granules at different developmental stages after anthesis in triticale.Evans Blue staining and analysis of DNA fragmentation indicated that cells of triticale endosperm undergo programmed cell death during its development.Dead cells within the endosperm were detected at 6 d post anthesis(DPA),and evidence of DNA fragmentation was first observed at 21 DPA.The period between initial detection of PCD to its rapid increase overlapped with the key stages of rapid starch accumulation during endosperm development.Cell death occurred stochastically throughout the whole endosperm,meanwhile,the activities of starch biosynthetic enzymes and the starch accumulation rate decreased in the late stages of grain filling.These results suggested that the timing and progression of PCD in triticale endosperm may interfere with starch synthesis and accumulation. | Chun-Yan Li Wei-Hua Li Cheng Li Denis A. Gaudet Andrd Laroche Lian-Pu Cao Zhen-Xiang Lu | 2010 | Journal of Integrative Plant Biology2010，52，7： | 3 |
| 5 | Partial or total replacement of fish meal by soybean protein on growth, protein utilization, potential estrogenic or antigenic effects, cholesterolemia and flesh quality in rainbow trout, Oncorhynchus mykiss显示文摘 | S.J. Kaushik J.P. Cravedi J.P. Lalles J. Sumpter B. Fauconneau M. Laroche | 1995 | Aquaculture1995，，3： | 2 |
| 6 | Understanding the biodegradation of polyurethanes: From classical implants to tissue engineering materials显示文摘 | J.P. Santerre K. Woodhouse G. Laroche R.S. Labow | 2005 | Biomaterials2005，，35： | 2 |
| 7 | Targeting consumers who are willing to pay more for environmentally friendly products显示文摘 | Michel Laroche Jasmin Bergeron Guido Barbaro-Forleo | 2001 | Journal of Consumer Marketing2001，，6： | 2 |
| 8 | DEM modelling of liner evolution and its influence on grinding rate in ball mills显示文摘 | M.S. Powell N.S. Weerasekara S. Cole R.D. LaRoche J. Favier | 2011 | Minerals Engineering2011，，3： | 2 |
| 9 | Increased vascularization in myeloma显示文摘 | Laroche M Brousset P Ludot I | 2001 | Eur J Hematol2001，66，1： | 1 |
| 10 | Triggered lightning in new mexico显示文摘 | Hubert P Laroche P Eybert-Berard A | 1984 | J Geophys Res1984，89，2： | 1 |
| 11 | Male osteoporosis with vertebral fractures? Look for ankylosing spondylitis! A report of 10 cases显示文摘 | Laroche M Lassoued S Billey T Bernard J Mazi B | | 0，，11： | 1 |
| 12 | Brand familiarity and confidence as determinants of purchase intention: an empirical test in a multiple brand context 显示文摘 | Laroche M Kim C Zhou L | 2010 | Critical Reviews in Biotechnology2010，26，4： | 1 |
| 13 | Tension control for winding systems with two-degrees-of-freedom H controllers 显示文摘 | DOMINIQUE Knittel EDOUARD Laroche DANIEL Gigan | 2003 | IEEE Transactions on Industry Applications2003，39，1： | 1 |
| 14 | Diagnostic value of dominant T-cell clones in peripheral blood in 363 patients presenting consecutively with a clinical suspicion of cutaneous lymphoma显示文摘 | Delfau-Larue MH Laroche L Wechsler J | 2000 | Blood2000，96，9： | 1 |
| 15 | Epilepsy in the elderly显示文摘 | LaRoche SM Helmers SL | 2003 | Neurologist2003，9，5： | 1 |
| 16 | Genetic variability in reared stocks of common carp ( Cyprinus carpio L)based on alloaymes and microsatellites显示文摘 | Desvignes J F Laroche J Durand J D | 2001 | Aquculture2001，，194： | 1 |
| 17 | The influence of country image structure on consumer evaluations of foreign products 显示文摘 | Laroche M | 2005 | Interna- tional Marketing Review2005，22，1： | 1 |
| 18 | The effects of social media based brand communities on brand community markers, val- ue creation practices, brand trust and brand loyalty显示文摘 | Laroche M Habibi M R Richard M | 2012 | Computers in Human Behavior2012，28，5： | 1 |
| 19 | Individualistic orientation and consumer susceptibility to interpersonal influence显示文摘 | Mehdi Mourali Michel Laroche Frank Pons | 2005 | Journal of Services Marketing2005，，3： | 1 |
| 20 | Near-Field Ther-mophotovoltaic Energy Conversion 显示文摘 | Laroche M Carminati R Greffet J J | 2006 | Journal of AppliedPhysics2006，100，06： | 1 |
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