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31篇 您的检索式:作者名="Lambert LJ"
    题名 作者 年代 出处 被引量
1β-Arrestin 1 and 2 and G protein-coupled receptor kinase 2 expression in pituitary adenomas:role in the regulation of response to somatostatin analogue treatment in patients with acromegaly显示文摘Recent in vitro studies highlighted G protein-coupled receptor kinase(GRK)2 andβ-arrestins as important players in driving somatostatin receptor(SSTR)desensitization and trafficking.Our aim was to characterize GRK2 andβ-arrestins expression in different pituitary adenomas and to investigate their potential role in the response to somatostatin analog(SSA)treatment in GHsecreting adenomas(GHomas).We evaluated mRNA expression of multiple SSTRs,GRK2,β-arrestin 1,andβ-arrestin 2 in 41pituitary adenomas(31 GHomas,6 nonfunctioning[NFPAs],and 4 prolactinomas[PRLomas]).Within the GHomas group,mRNA data were correlated with the in vivo response to an acute octreotide test and with the GH-lowering effect of SSA in cultured primary cells.β-Arrestin 1 expression was low in all 3 adenoma histotypes.However,its expression was significantly lower in GHomasGatto F Feelders R van der Pas R Kros JM Dogan F van Koetsveld PM van der Lelij AJ Neggers SJ Minuto F de Herder W Lamberts SW Ferone D Hofland LJ 2013中国神经肿瘤杂志2013,11,4:2
2Somatostatin analogs:clinical application in relation to human somatostatin receptor subtypes显示文摘Hofland LJ Lambert SWJ 0,,:1
3显示文摘 Lambert LJ Remington J 1999Antimicrob Agents Chemother1999,43,4:1
4Maternal microchimerism in healthy adults in lymphocytes,monocyte/ macrophages and NK cells显示文摘Loubière LS Lambert NC Flinn LJ 0,,11:1
5The pathophysiological consequences of somatostatin receptor internalization and resistance显示文摘Hofland LJ Lamberts SW Endocr Rev0,24,1:1
6Somatostatin receptor subtype expression in human tumors 显示文摘Hofland LJ Lamberts SW 2001Ann Oneol2001,12,2:1
7Future clinical prospects in somatostatin/cortistatin/somatostatin receptorfield显示文摘Dalm VA Hofland LJ and Lamberts SW 2008Mol Cell Endocrinol2008,286,12:1
8Octreotide and related somatostatin analogs in the diagnosis and treatment of pituitary disease and somatostatin receptor scintigraphy 显示文摘Lamberts SW Hofland LJ de Herder WW 1993Front Neuroendocrinol1993,14,1:1
9Octreotide显示文摘Lambert SWJ Lely AJ Herder WW Hofland LJ 1996N Engl J Med1996,334,5:1
10Functionality of short chain amylose-lipid complexes in starch-water systems and their impact on in vitro starch degradation显示文摘Putseys JA Derde LJ Lamberts L 2010Journal of Agricultural and Food Chemistry2010,58,:1
11Somatostatin receptors in pituitary func- tion, diagnosis and therapy显示文摘Hofland LJ Lamberts SW 2004Front Horm Res2004,32,:1
12Somatostatin analogs in the diagnosis and treatment of cancer显示文摘Lamberts SW de Herder WW Hofland LJ 2002Trends Endocrinol Metab2002,13,10:1
13Neuroendocrine tumor markers显示文摘Lamberts SW Hofland LJ Nobels FR 2001Front Neuroendocrinol2001,22,4:1
14Somatostatin analogs in the diagnosis and treatment of cancer 显示文摘Lamberts SWJ de Herder WW Holland LJ 2002Trends Endocrinol Metab2002,13,10:1
15Somatostatin analogs in the diagnosis and treatment of cancer显示文摘Lamberts SWL de Herder WW Hofland LJ 2002Trends Endocrinol Metab2002,13,2:1
16Somatostatin analogs in the diagnosis and treatment of cancer显示文摘Lamberts SW De Herder WW Hofland LJ 2002Trends Endocrinol Metab2002,13,10:1
17Neuroendocrine tumor mark- ers显示文摘Lamberts SW Hofland LJ Nobels FR 2001Front Neuroendocrinol2001,22,4:1
18Antimicrobial efficacy of copper surfaces against spores and vegetative cells of Clostridium difficile : the germination theory 显示文摘Wheeldon LJ Worthington T Lambert PA 2008J Antimicrob Chemother2008,62,3:1
19Somatostatin analogs in the diagnosis and treatment of cancer显示文摘Lamberts SW de Herder WW Hofland LJ 2002Trends Endoerinol Metab2002,13,10:1
20Cushing's syndrome: an update on current pharmacotherapy and future directions显示文摘Creemers SG Hofland LJ Lamberts SW 2015Expert Opin Pharmaeother2015,16,12:1
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