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| 1 | Adaptive optical focusing through perturbed scattering media with a dynamic mutation algorithm显示文摘Optical imaging through or inside scattering media, such as multimode fiber and biological tissues, has a significant impact in biomedicine yet is considered challenging due to the strong scattering nature of light. In the past decade, promising progress has been made in the field, largely benefiting from the invention of iterative optical wavefront shaping, with which deep-tissue high-resolution optical focusing and hence imaging becomes possible. Most of the reported iterative algorithms can overcome small perturbations on the noise level but fail to effectively adapt beyond the noise level, e.g., sudden strong perturbations. Reoptimizations are usually needed for significant decorrelation to the medium since these algorithms heavily rely on the optimization performance in the previous iterations. Such ineffectiveness is probably due to the absence of a metric that can gauge the deviation of the instant wavefront from the optimum compensation based on the concurrently measured optical focusing.In this study, a square rule of binary-amplitude modulation, directly relating the measured focusing performance with the error in the optimized wavefront, is theoretically proved and experimentally validated. With this simple rule, it is feasible to quantify how many pixels on the spatial light modulator incorrectly modulate the wavefront for the instant status of the medium or the whole system. As an example of application, we propose a novel algorithm, the dynamic mutation algorithm, which has high adaptability against perturbations by probing how far the optimization has gone toward the theoretically optimal performance. The diminished focus of scattered light can be effectively recovered when perturbations to the medium cause a significant drop in the focusing performance, which no existing algorithms can achieve due to their inherent strong dependence on previous optimizations. With further improvement, the square rule and the new algorithm may boost or inspire many applications, such as high-resolution optical imaging and stimulation, in instable or dynamic scattering environments. | HUANHAO LI CHI MAN WOO TIANTING ZHONG ZHIPENG YU YUNQI LUO YUANJIN ZHENG XIN YANG HUI HUI PUXIANG LAI | 2021 | Photonics Research2021，9，2： | 6 |
| 2 | Dynamic response analysis of a multiple-beam structure subjected to a moving load显示文摘In this study,the dynamic response of an elastically connected multi-beam structure subjected to a moving load with elastic boundary conditions is investigated.The boundary conditions and properties of each beam vary,and the difficulty of solving the motion equation is reduced by using a Fourier series plus three special transformations.By examining a high-speed railway(HSR)with mixed boundary conditions,the rationality for the newly proposed method is verified,the difference in simulated multiple-beam models with different beam numbers is explored,and the influence of material parameters and load speed on the dynamic response of multiple-beam structures is examined.Results suggest that the number of beams in the model should be as close to the actual beam number as possible.Models with an appropriate beam number can be used to describe in detail the dynamic response of the structure.Neglecting the track-structure can overestimate the resonant speed of a high-speed railway,simply-supported beam bridge.The effective interval of foundation stiffness(EIFS)can provide a reference for future engineering designs. | Zhang Yuntai Jiang Lizhong Zhou Wangbao Liu Shaohui Feng Yulin Liu Xiang Lai Zhipeng | 2022 | Earthquake Engineering and Engineering Vibration2022，21，3： | 2 |
| 3 | In-situ generation and global property profiling of metal nanoclusters by ultraviolet laser dissociation-mass spectrometry显示文摘Metal nanoclusters are promising nanomaterials with unique properties, but only a few ones with specific numbers of metal atoms can be obtained and studied up to now. In this study, we establish a new paradigm of in-situ generation and global study of metal nanoclusters with different sizes, constitutions, and charge states, including both accurate constitution characterization and global activity profiling. The complex mixtures of metal nanoclusters are produced by employing single-pulsed 193-nm laser dissociation of monolayer-protected cluster(MPC) precursors within a high-resolution mass spectrometry(HRMS). More than400 types of bare gold nanoclusters including novel multiply charged(2+ and 3+), S-/P-doped, and silver alloy ones can be efficiently generated and accurately characterized. A distinct size(1 to 142 atoms)-and charge(1+ to 3+)-hierarchy reactivity is clearly observed for the first time. This global cluster study might greatly promote the developments and applications of novel metal nanoclusters. | Zheyi Liu Zhaoxian Qin Chaonan Cui Zhixun Luo Bing Yang You Jiang Can Lai Zhipeng Wang Xiaolei Wang Xiang Fang Gao Li Fangjun Wang Chunlei Xiao Xueming Yang | 2022 | Science China Chemistry2022，65，6： | 2 |
| 4 | Active wavefront shaping for controlling and improving multimode fi ber sensor显示文摘Wavefront shaping(WFS)techniques have been used as a powerful tool to control light propagation in complex media,including multimode fibers.In this paper,we propose a new application of WFS for multimode fber-based sensors.The use of a single multimode fiber alone,without any special fabrication,as a sensor based on the light intensity variations is not an easy task.The twist effect on multimode fiber is used as an example herein.Experimental results show that light intensity through the multimode fiber shows no direct relationship with the twist angle,but the correlation coefficient(CC)of speckle patterns does.Moreover,if WFS is applied to transform the spatially seemingly random light pattern at the exit of the multimode fiber into an optical focus.The focal pattern correlation and intensity both can serve to gauge the twist angle,with doubled measurement range and allowance of using a fast point detector to provide the feedback.With further development,WFS may find potentials to facilitate the development of multimode fber-based sensors in a variety of scenarios. | Tianting Zhong Zhipeng Yu Huanhao Li Zihao Li Haohong Li Puxiang Lai | 2019 | Journal of Innovative Optical Health Sciences2019，，4： | 1 |
| 5 | The importance of coil conductivity and eddy current effects in the analysis of electromagnetic forming process显示文摘Coil design and performance analysis are critical for the electromagnetic forming(EMF)process.However,previous studies have paid little attention to the coil con-ductivity,and the influence of eddy current effects in coil conductors on the forming process has not been well understood.This work aims to address these problems through numerical and experimental investigations.It is found that,due to the eddy current effects,the uneven current distribution appears in the coil conductors that should be considered when analysing the forming process,especially for the cases with large heights of coil conductors.Meanwhile,an important and interesting discovery is that the eddy current effects can greatly reduce the sensitivity of the coil conductivity with respect to the workpiece deformation,the Joule heating and the temperature rise in the coil.For instance,compared to a forming system with a copper coil,the forming height of the workpiece in the forming system with an AA5083‐O coil is reduced by less than 5%under the same discharge energy,while the copper conductivity is 3.3 times that of the latter.These results are helpful to understand the EMF process and achieve the optimal design of coils. | Quanliang Cao Liangyu Xia Xian Li Limeng Du Zhipeng Lai Xiaotao Han Liang Li | 2022 | High Voltage2022，7，2： | 1 |
| 6 | Degradation of metronidazole by dielectric barrier discharge in an aqueous solution显示文摘Degradation of metronidazole (MNZ) which is a representative and stable antibiotic by dielectric barrier discharge (DBD) in an aqueous solution has been studied. Effects of initial MNZ concentration, solution pH and coexisting organics on the degradation were investigated. The results illustrated that increasing the input power and the discharge frequency can improve the removal of MNZ. At low initial concentration, the removal of MNZ can reach up to 99.1%. Acidic and neutral conditions are more favorable for MNZ removal than alkaline condition in the early stage of degradation. However, the difference in MNZ removal between those in acidic or neutral media and that in alkaline one could be neglected with prolonging of the treatment time. Therefore, this method can be applied to MNZ degradation with a wide pH range. Coexisting organic matter in water can attenuate the removal to some extent. This study could provide valuable references for the degradation of nitroimidazole antibiotics by DBD. | Zhipeng Yang Anxing Lai Hangyu Chen Youxiang Yan Ye Yang Weiwei Zhang Lei Wang | 2019 | Frontiers of Environmental Science & Engineering2019，13，3： | 1 |
| 7 | Dynamic Analyses of a Simply Supported Double-Beam System Subject to a Moving Mass with Fourier Transform Technique显示文摘In order to study the dynamic characteristics of a simply supported double-beam system under a moving mass,the system of fourth-order dynamic partial differential equations of a simply supported double-beam system was transformed into a system of second-order dynamic ordinary differential equations relative to time coordinates by performing the finite sin-Fourier Transform relative to space coordinates.And the analytical solution of the dynamic response of the simply supported double-beam system under a moving mass was obtained by solving the system of dynamic ordinary differential equations.The analytical method and ANSYS numerical method were used to calculate the dynamic responses of several simply supported double-beam systems under a moving mass at different speeds.The influences of inertial effect,mass movement speed,and Winkler-layer spring stiffness and damping on the dynamic responses of simply supported double-beam systems were analyzed.According to the study results,the analytical calculation results in this paper fit well with the ANSYS finite element numerical calculation results,demonstrating the rationality of the analytical method.The inertial effect has a significant influence on the dynamic response characteristics of the simply supported double-beam system.The simply supported double-beam system underwent several resonant speeds under a moving mass,and the Winkler-layer spring stiffness has a relatively significant effect on the vibration of the first beam. | Lizhong Jiang Xilin Chai Zhihua Tan Wangbao Zhou Yulin Feng Zhipeng Lai Lan Zheng | 2019 | Computer Modeling in Engineering & Sciences2019，，10： | 1 |
| 8 | Wavefront shaping: A versatile tool to conquer multiple scattering in multidisciplinary fields显示文摘Optical techniques offer a wide variety of applications as light-matter interactions provide extremely sensitive mechanisms to probe or treat target media.Most of these implementations rely on the usage of ballistic or quasi-ballistic photons to achieve high spatial resolution.However,the inherent scattering nature of light in biological tissues or tissue-like scattering media constitutes a critical obstacle that has restricted the penetration depth of non-scattered photons and hence limited the implementation of most optical techniques for wider applications.In addition,the components of an optical system are usually designed and manufactured for a fixed function or performance.Recent advances in wavefront shaping have demonstrated that scattering-or component-induced phase distortions can be compensated by optimizing the wavefront of the input light pattern through iteration or by conjugating the transmission matrix of the scattering medium. | Zhipeng Yu Huanhao Li Tianting Zhong Jung-Hoon Park Shengfu Cheng Chi Man Woo Qi Zhao Jing Yao Yingying Zhou Xiazi Huang Weiran Pang Hansol Yoon Yuecheng Shen Honglin Liu Yuanjin Zheng YongKeun Park Lihong V.Wang Puxiang Lai | 2022 | The Innovation2022，3，5： | 1 |
| 9 | Cyclin D1 G870A polymorphism and the risk of hepatocellular carcinoma in a Chinese population显示文摘 | Zhangyong Hu Zhipeng Zhou Guolian Xiong Yali Wang Yi Lai Lan Deng Jinliang Yang | 2014 | Tumor Biology2014，，6： | 1 |
| 10 | Enhancing spatiotemporal focusing of light deep inside scattering media with Time-Gated Reflection Matrix显示文摘Time-gated reflection matrix(RM)has been successfully used for optical imaging deep inside Scattering media.Recently,this method was extended to enhance the spatiotemporal focusing of light ultra-deep inside scattering media.This is achieved by calibrating the decomposition of the RM with the Tikhonov regularization parameter to convert mutiply scattered photons that share the same time of flight with the singly scattered photons into singly scattered photons.Such a capability suggests a reshaping to the interaction mechanism between light and scattering media,which may beneft or inspire wide optical applications that desire enhanced spatiotemporal focusing of light at depths inside scattering media. | Zhipeng Yu Huanhao Li Tianting Zhong Puxiang Lai | 2022 | Light(Science & Applications)2022，11，7： | 1 |
| 11 | Learning-based super-resolution interpolation for sub-Nyquist sampled laser speckles显示文摘Information retrieval from visually random optical speckle patterns is desired in many scenarios yet considered challenging.It requires accurate understanding or mapping of the multiple scattering process,or reliable capability to reverse or compensate for the scattering-induced phase distortions.In whatever situation,effective resolving and digitization of speckle patterns are necessary.Nevertheless,on some occasions,to increase the acquisition speed and/or signal-to-noise ratio(SNR),speckles captured by cameras are inevitably sampled in the sub-Nyquist domain via pixel binning(one camera pixel contains multiple speckle grains)due to finite size or limited bandwidth of photosensors.Such a down-sampling process is irreversible;it undermines the fine structures of speckle grains and hence the encoded information,preventing successful information extraction.To retrace the lost information,super-resolution interpolation for such sub-Nyquist sampled speckles is needed.In this work,a deep neural network,namely SpkSRNet,is proposed to effectively up sample speckles that are sampled below 1/10 of the Nyquist criterion to well-resolved ones that not only resemble the comprehensive morphology of original speckles(decompose multiple speckle grains from one camera pixel)but also recover the lost complex information(human face in this study)with high fidelity under normal-and low-light conditions,which is impossible with classic interpolation methods.These successful speckle super-resolution interpolation demonstrations are essentially enabled by the strong implicit correlation among speckle grains,which is non-quantifiable but could be discovered by the well-trained network.With further engineering,the proposed learning platform may benefit many scenarios that are physically inaccessible,enabling fast acquisition of speckles with sufficient SNR and opening up new avenues for seeing big and seeing clearly simultaneously in complex scenarios. | HUANHAO LI ZHIPENG YU QI ZHAO YUNQI LUO SHENGFU CHENG TIANTING ZHONG CHI MAN WOO HONGLIN LIU LIHONG V.WANG YUANJIN ZHENG PUXIANG LAI | 2023 | Photonics Research2023，11，4： | 0 |
| 12 | Genome-wide association with transcriptomics reveals a shade-tolerance gene network in soybean显示文摘Shade tolerance is essential for soybeans in inter/relay cropping systems.A genome-wide association study(GWAS)integrated with transcriptome sequencing was performed to identify genes and construct a genetic network governing the trait in a set of recombinant inbred lines derived from two soybean parents with contrasting shade tolerance.An improved GWAS procedure,restricted two-stage multi-locus genome-wide association study based on gene/allele sequence markers(GASM-RTM-GWAS),identified 140 genes and their alleles associated with shade-tolerance index(STI),146 with relative pith cell length(RCL),and nine with both.Annotation of these genes by biological categories allowed the construction of a protein–protein interaction network by 187 genes,of which half were differentially expressed under shading and non-shading conditions as well as at different growth stages.From the identified genes,three ones jointly identified for both traits by both GWAS and transcriptome and two genes with maximum links were chosen as beginners for entrance into the network.Altogether,both STI and RCL gene systems worked for shade-tolerance with genes interacted each other,this confirmed that shadetolerance is regulated by more than single group of interacted genes,involving multiple biological functions as a gene network. | Yanzhu Su Xiaoshuai Hao Weiying Zeng Zhenguang Lai Yongpeng Pan Can Wang Pengfei Guo Zhipeng Zhang Jianbo He Guangnan Xing Wubin Wang Jiaoping Zhang Zudong Sun Junyi Gai | 2024 | The Crop Journal2024，12，1： | 0 |
| 13 | Towards ideal focusing of diffused light via optical wavefront shaping显示文摘Multiple scattering can significantly scramble the amplitude and phase profile of an optical field.It obscures subtle observations but only speckle patterns can be seen,unlike the ballistic regime where the information or the optical field can be identified with limited distortions.Efficient optical manipulation including information transmission and precise focusing is therefore obstructed as light travels deep into turbidmedia such as fog,turbid fluids,and biological tissues. | Huanhao Li Zhipeng Yu Tianting Zhong Shengfu Cheng Puxiang Lai | 2023 | Advanced Photonics2023，5，2： | 0 |
| 14 | Accelerating deep learning with high energy efficiency:From microchip to physical systems显示文摘In the era of digits and intemet,massive data have been continuously gener-ated from a variety of sources,including video,photo,audio,text,intemet of things,etc.It is intuitive that more accurate pattems can be obtained by feeding more data for effective analysis;despite the data redundancy,a clearer picture can be delineated for better decision-making.However,traditional methods,even in machine learning,do not benefit from the expanding amount of data,whose perfomance nearty saturates when the data collection is large enough(Figure 1A).Such a dilemma emerges due to their limited capability and insuff cient supply of computation power in the past. | Huanhao Li Zhipeng Yu Qi Zhao Tianting Zhong Puxiang Lai | 2022 | The Innovation2022，3，4： | 0 |
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