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| 1 | Coupling strategies for silicon photonics integrated chips[Invited]显示文摘Over the last 20 years, silicon photonics has revolutionized the field of integrated optics, providing a novel and powerful platform to build mass-producible optical circuits. One of the most attractive aspects of silicon photonics is its ability to provide extremely small optical components, whose typical dimensions are an order of magnitude smaller than those of optical fiber devices. This dimension difference makes the design of fiberto-chip interfaces challenging and, over the years, has stimulated considerable technical and research efforts in the field. Fiber-to-silicon photonic chip interfaces can be broadly divided into two principle categories:in-plane and out-of-plane couplers. Devices falling into the first category typically offer relatively high coupling efficiency, broad coupling bandwidth(in wavelength), and low polarization dependence but require relatively complex fabrication and assembly procedures that are not directly compatible with wafer-scale testing.Conversely, out-of-plane coupling devices offer lower efficiency, narrower bandwidth, and are usually polarization dependent. However, they are often more compatible with high-volume fabrication and packaging processes and allow for on-wafer access to any part of the optical circuit. In this paper, we review the current state-of-the-art of optical couplers for photonic integrated circuits, aiming to give to the reader a comprehensive and broad view of the field, identifying advantages and disadvantages of each solution. As fiber-to-chip couplers are inherently related to packaging technologies and the co-design of optical packages has become essential, we also review the main solutions currently used to package and assemble optical fibers with silicon-photonic integrated circuits. | RICCARDO MARCHETTI COSIMO LACAVA LEE CARROLL KAMIL GRADKOWSKI PAOLO MINZIONI | 2019 | Photonics Research2019，7，2： | 19 |
| 2 | Renal biopsy:Still a landmark for the nephrologist显示文摘Renal biopsy was performed for the first time more than one century ago, but its clinical use was routinely introduced in the 1950s. It is still an essential tool for diagnosis and choice of treatment of several primary or secondary kidney diseases. Moreover, it may help to know the expected time of end stage renal disease. The indications are represented by nephritic and/or nephrotic syndrome and rapidly progressive acute renal failure of unknown origin. Nowadays, it is performed mainly by nephrologists and radiologists using a 14-18 gauges needle with automated spring-loaded biopsy device, under realtime ultrasound guidance. Bleeding is the major primary complication that in rare cases may lead to retroperitoneal haemorrhage and need for surgical intervention and/or death. For this reason, careful evaluation of risks and benefits must be taken into account, and all procedures to minimize the risk of complications must be observed. After biopsy, an observation time of 12-24 h is necessary, whilst a prolonged observation may be needed rarely. In some cases it could be safer to use different techniques to reduce the risk of complications, such as laparoscopic or transjugular renal biopsy in patients with coagulopathy or alternative approaches in obese patients. Despite progress in medicine over the years with the introduction of more advanced molecular biology techniques, renal biopsy is still an irreplaceable tool for nephrologists. | Luca Visconti Valeria Cernaro Carlo Alberto Ricciardi Viviana Lacava Vincenzo Pellicanò Antonio Lacquaniti Michele Buemi Domenico Santoro | 2016 | World Journal of Nephrology2016，5，4： | 3 |
| 3 | Biological effects of magnetic fluids toxicity studies 显示文摘 | Lacava Z G M Azevedo R B Martins E V | 1999 | J Magn Magnetic Mater1999，201，： | 1 |
| 4 | PSA Performance of Densely Packed Adsorbent Beds 显示文摘 | LaCava A I | 1995 | AIChE J1995，41，6： | 1 |
| 5 | Long-term bio- distribution and blocompatibillty investigation of dextran-coated magnetite nanoparticle using mice as the animal model 显示文摘 | Estevanato LL Lacava LM Carvalho LC | 2012 | J Biomed Nanotechnal2012，8，2： | 1 |
| 6 | Biological effects of magnetic fluids:toxicity studies显示文摘 | LACAVA Z G M AZEVEDO R B MARTINS E V | 1999 | J Magn Magn Mater1999，201，17： | 1 |
| 7 | Diversity of endo- phytic yeasts from sweet orange and their localization by scan- ning electron microscopy 显示文摘 | CS Gai PT Lacava W Maccheroni Jr | 2009 | Basic Microbiol2009，49，5： | 1 |
| 8 | Epidemiology of thrombotic-hemostatic factors and their associations with cardiovascular disease显示文摘 | Person TA Lacava J Well HFC | 1997 | Am J Clin Nutr1997，，： | 1 |
| 9 | Family-based association study of the MTHFR polymorphism C677T in patients with nonsyndromic cleft lip and palate from central Europe 显示文摘 | Reutter H Birnbaum S Lacava AD | 2008 | Cleft Palate Craniofac J2008，45，3： | 1 |
| 10 | Soil moistureestimation through ASCAT and AMSR-E sensors:anintercomparison and validation study across Europe显示文摘 | Brocca L Hasenauer S Lacava T | 2011 | Remote Sensing of Environment-2011，115，12： | 1 |
| 11 | Long-term retention of dextran-coated magnetite nanoparticles in the liver and spleen 显示文摘 | Lacava L Garcia V Kuckelhaus S | 2004 | J Mag:netism and Magnetic Mater2004，，272276： | 1 |
| 12 | Robust Satel- lite Techniques for oil spill detection and monitoring u- sing AVHRR thermal infrared bands 显示文摘 | Casciello D Lacava T Pergola N | 2011 | International Journal of Remote Sensing2011，32，14： | 1 |
| 13 | Space-time soil wetness variations monitoring by a multi-temporal microwave satellite records analysis显示文摘 | LACAVA T DILEO E V PERGOLA N | 2006 | Physics and Chemistry of the Earlh Part B: Hydrology Oceans and Atmosphere2006，31，18： | 1 |
| 14 | A first assessment of theSMOS soil moisture product with in situ and modeled data inItaly and luxembourg 显示文摘 | Lacava T Matgen P Brocca L | 2012 | IEEE Transactions on Geoscienceand Remote Sensing2012，50，5： | 1 |
| 15 | Long-term retention of dextran-coated magnetite nanoparticles in the liver and spleen显示文摘 | Lacava LM Garcia VAP Kuckelhaus S | 2004 | J Magn Magn Mater2004，，： | 1 |
| 16 | Cdk4 deficiency inhibits skin tmnor development but does not affect normal keratinocyte proliferation显示文摘 | Rodriguez-Puebla ML Miliani de Marval PL LaCava M | 2002 | Am J Pathol2002，161，40： | 1 |
| 17 | Vinorelbine as neoadjuavart chemotherapy in advancecl cervical covrcinoma显示文摘 | Lacava JA Leone BA Machiavellim | 2007 | J Clin Qncol2007，15，4： | 1 |
| 18 | Somatic comorbidities and Alzheimer’s disease treatment显示文摘 | Alessandra Clodomiro Pietro Gareri Gianfranco Puccio Francesca Frangipane Roberto Lacava Alberto Castagna Valeria Graziella Laura Manfredi Rosanna Colao Amalia Cecilia Bruni | 2013 | Neurological Sciences2013，，9： | 1 |
| 19 | Light microscopy and magnetic resonance characterization of a DMSA-coated magnetic fluid in mice 显示文摘 | Chaves S B Lacava L M Lacava Z G M | 2002 | IEEE Transactions on Magnetics2002，38，5： | 1 |
| 20 | 3-Hydroxypropionic acid as an antibacterial agent from endophytic fungi Diaporthe phaseolorum 显示文摘 | Sebastianes FLS Cabedo N Aouad NEI Valente AMMP Lacava PT Azevedo JL Pizzirani-Kleiner AA Cortes D | 2012 | Curr Microbiol2012，65，5： | 1 |
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