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52篇 您的检索式：作者名="Labile"

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	题名	作者	年代	出处	被引量
1	Expression of 5-Lipoxygenase in human colorectal cancer显示文摘AIM: To evaluate the 5-lipoxygenases (Loxs) expression level in human colorectal cancer specimens in order to determine its clinicopathologic significance in human tumorigenesis. METHODS: The relative quantity of 5-Lox mRNA in paired 91 colorectal tumor and adjacent normal mucosa samples was determined by real time quantitative PCR. Additionally, the expression of 5-Lox and cyclooxygenase (Cox)-2 proteins was also examined using immunohistochemical staining methods. RESULTS: There was a marked increase in 5-Lox mRNA levels in the tumor compared with paired normal mucosa samples (P < 0.0001). Sixty six (72.5%) tumors showed high 5-Lox mRNA levels. The positivity rate of 5-Lox and Cox-2 protein expression was 68.7% and 79.1% respectively. There was a significant association between tumoral 5-Lox mRNA level and tumor size (Rho = 0.392, P = 0.0002), depth or vessel invasion. CONCLUSION: These results suggest that 5-Lox is up-regulated in colorectal cancer and that inhibition of its expression might be valuable in the prevention and treatment of colorectal cancer.	Labile Togba Soumaoro Satoru Iida Hiroyuki Uetake Megumi Ishiguro Yoko Takagi Tetsuro Higuchi Masamichi Yasuno Masayuki Enomoto Kenichi Sugihara	2006	World Journal of Gastroenterology2006，12，39：	3
2	Advantages of combination therapy in previously untreated and treated patients with advanced Prostatic Cancer显示文摘	Labile F Dupont A Giguere M	1986	J Steroid Biochem1986，，：	1
3	Screening decreases prostate cancer mortality:11-year follow-up of the 1988 Quebec prospective randomized controlled trial显示文摘	Labile F Candas B Cusan L	2004	Prostate2004，59，3：	1
4	Preparation of amino-functionalized silica in aqueous conditions显示文摘	Cuoq F Masion A Labille J Rose J Ziarelli F Prelot B Bottero J Y	2013	Applied Surface Science2013，266，：	1
5	A comparative molecular field and comparative molecular similarity indices analyses ( CoMFA and CoMSIA ) of N-phenyl-N'-( 2-chloroethyl) ureas targeting the colchieine-binding site as anticancer agents 显示文摘	Fortin S Labile P Moreau E	2008	Bioor Med Chem2008，16，4：	1
6	Cyclooxygenase-2 Expression: A Significant Prognostic Indicator for Patients With Colorectal Cancer 显示文摘	Labile TS Hiroyuki U Tetsuro H	2004	Clin Cancer Res2004，10，24：	1
7	sagittal plane analy- sis of the spine and pelvis in adolescent idiopathic scoliosis according to the coronal curve type显示文摘	Mac - Thiong JM Labile H Charlebois M	2003	Spine2003，28，：	1
8	Is dehydroepiandrosterone a hormone? 显示文摘	Labile F Luu-The V Belanger A	2005	Journal of Endocrinology2005，187，：	1
9	Pathogen inactivation of labile blood products显示文摘	Council of Europe Expert Committee in Blood Transfusion Study Group on Pathogen Inactivation of Labile Blood Components	2001	Transfus Med2001，11，3：	1
10	Benign schwannoma of the pancreas显示文摘	Labile Togba Soumaoro Kenichi Teramoto Tohru Kawamura Noriaki Nakamura Takahiro Sanada Kenichi Sugihara Shigeki Arii	2005	Journal of Gastrointestinal Surgery2005，，2：	1
11	Molecular cloning and characterization of the ferric hydroxamate uptake (thu) operon in Actinobacillus pleuropneumoniae 显示文摘	Mikael L G Pawelek P D Labile J	2002	Microbiology2002，148，9：	1
12	Rule of Smadl and Smad4 proteins in the induction of p21WAFi,Cipl during bone morphogenetie protein-induced growth arrest in human breast cancer cells显示文摘	Pouliot F Labile C	2002	J Endocrinol2002，172，1：	1
13	Ligand- independent recruitment of SRC1 to estrogen receptor beta through phosphorylation of activation function A F- 1 显示文摘	Tremblay A Tremblay G B Labile F	2001	Mol Cell2001，3，：	1
14	Androgen receptor antagonists:structure activity relationships显示文摘	Cauthier S Labile F	2000	Curr Meb Chem2000，7，2：	1
15	Intravaginal de- hydroepiandrosterone (Prasterone),a physiological and highly efficienttreatment of vaginal atrophy 显示文摘	Labile F Archer D Bouchard C	2009	Menopause2009，16，：	1
16	Effect of intrav- aginal dehydroepiandrosterone (Prasterone) on libido and sexual dysfunction in postmenopausal women 显示文摘	Labile F Archer D Bouchard C	2009	Menopause2009，16，：	1
17	Effect of intrav- aginal prasterone on sexual dysfunction in post- menopausal women with vulvovaginal atrophy 显示文摘	Labile F Derogatis L Archer DF	2015	J Sex Med2015，12，12：	1
18	Intra-and inter-brand ac- curacy of four dental radiometers 显示文摘	Price RB Labile D Kazmi S	2012	Clin Oral Investig2012，16，3：	1
19	Efficacy of intrav- aginal dehydroepiandrosterone (DHEA) on moderate to severe dyspareunia and vaginal dryness,symptoms of vulvovaginal atrophy,and of the genitourinary syndrome of menopause 显示文摘	Labile F Archer DF Koltun W	2016	Menopause2016，23，3：	1
20	Low serum levels of sex-steroids are associated with disease characteristics in primmy Sjogren's syndrome; supplementation with dehydro-epiandrosterone restores the concentrations 显示文摘	Forsblad-d'Elia H Carlsten H Labile F	2009	Clin Endocrinol Metab2009，94，6：	1

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