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| 1 | Volar locking distal radius plates show better short-term results than other treatment options: A prospective randomised controlled trial显示文摘AIM To compare the outcomes of displaced distal radius fractures treated with volar locking plates and with immediate postoperative mobilisation with the outcomes of these fractures treated with modalities that necessitate 6 wk wrist immobilisation.METHODS A prospective, randomised controlled single-centre trial was conducted with 56 patients who had a displaced radius fracture were randomised to treatment either with a volar locking plate(n = 29), or another treatment modality(n = 27; cast immobilisation with or without wires or external fixator). Outcomes were measured at 12 wk. Functional outcome scores measured were the Patient-Rated Wrist Evaluation(PRWE) Score; Disabilities of the Arm, Shoulder and Hand and activities of daily living(ADLs). Clinical outcomes were wrist range of motion and grip strength. Radiographic parameters were volar inclination and ulnar variance.RESULTS Patients in the volar locking plate group had significantly better PRWE scores, ADL scores, grip strength and range of extension at three months compared with the control group. All radiological parameters were significantly better in the volar locking plate group at 3 mo. CONCLUSION The present study suggests that volar locking plates produced significantly better functional and clinical outcomes at 3 mo compared with other treatment modalities. Anatomical reduction was significantly more likely to be preserved in the plating group. Level of evidence: Ⅱ. | Herwig Drobetz Lidia Koval Patrick Weninger Ruth Luscombe Paula Jeffries Stefan Ehrendorfer Clare Heal | 2016 | World Journal of Orthopedics2016，7，10： | 18 |
| 2 | Functional gastrointestinal disorders in eating disorder patients:Altered distribution and predictors using ROME Ⅲ compared to ROME Ⅱ criteria显示文摘AIM:To compare the prevalence of Functional gastrointestinal disorders(FGIDs)using ROMEⅢand ROMEⅡand to describe predictors of FGIDs among eating disorder(ED)patients.METHODS:Two similar cohorts of female ED inpatients,aged 17-50 years,with no organic gastrointestinal or systemic disorders,completed either the ROMEⅢ(n=100)or the ROMEⅡ(n=160)questionnaire on admission for ED treatment.The two ROME cohorts were compared on continuous demographic variables(e.g.,age,BMI)using Student’s t-tests,and on categorical variables(e.g.,ED diagnosis)usingχ2-tests.The relationship between ED diagnostic subtypes and FGID categories was explored usingχ2-tests.Age,BMI,and psychological and behavioural predictors of the common(prevalence greater than 20%)ROMEⅢFGIDs were tested using logistic regression analyses.RESULTS:The criteria for at least one FGID were fulfilled by 83%of the ROMEⅢcohort,and 94%of the ROMEⅡcohort.There were no significant differences in age,BMI,lowest ever BMI,ED diagnostic subtypes or ED-related quality of life(QOL)scores between ROMEⅡand ROMEⅢcohorts.The most prevalent FGIDs using ROMEⅢwere postprandial distress syndrome(PDS)(45%)and irritable bowel syndrome(IBS)(41%),followed by unspecified functional bowel disorders(U-FBD)(24%),and functional heartburn(FH)(22%).There was a 29%or 46%increase(depending on presence or absence of cyclic vomiting)in functional gastroduodenal disorders because of the introduction of PDS in ROMEⅢcompared to ROMEⅡ.There was a 35%decrease in functional bowel disorders(FBD)in RomeⅢ(excluding U-FBD)compared to ROMEⅡ.The most significant predictor of PDS was starvation(P=0.008).The predictor of FH(P=0.021)and U-FBD(P=0.007)was somatisation,and of IBS laxative use(P=0.025).Age and BMI were not significant predictors.The addition of the 6-mo duration of symptoms requirement for a diagnosis in ROMEⅢadded precision to many FGIDs.CONCLUSION:ROMEⅢconfers higher precision in diagnosing FGIDs but self-induced vomiting should be excluded from the diagnosis of cyclic vomiting.Psychological factors appear to be more influential in ROMEⅡthan ROMEⅢ. | Xiaojie Wang Georgina M Luscombe Catherine Boyd John Kellow Suzanne Abraham | 2014 | World Journal of Gastroenterology2014，20，43： | 4 |
| 3 | A randomised comparison of parecoxib versus placebo for pain management following minor day stay gynaecological surgery显示文摘 | Luscombe K S McDonnell N J Muchatuta N A Paech M J Nathan E A | 2010 | Anaesthesia and Intensive Care2010，，1： | 2 |
| 4 | Enhancing the Thermal Stability of Polythiophene:Fullerene Solar Cells by Decreasing EffectivePolymer Regioregularity显示文摘 | Sivula K Luscombe C K Thompson B C | 2006 | J Am Chem Soc2006，，13： | 1 |
| 5 | Competition in vivo between a cytopathic variant and a wild-type duck hepatitis B virus显示文摘 | Lenhoff RJ Luscombe CA Summers J | 1998 | Virology1998，251，： | 1 |
| 6 | A study of some variables in a tetrazolium dye(MTT)based assay for cell growth and chemosensitivity显示文摘 | Twentyman PR Luscombe M | | 0，，： | 1 |
| 7 | Use of 14C l-sodium bicarbonate/urea to measure total energy expenditure in overweight men and women before and after low calorie diet induced weight loss 显示文摘 | Luscombe ND Tsopelas C Bellon M | 2006 | Asia Pac 3 Clin Nutr2006，15，3： | 1 |
| 8 | Acute liver injury following infection with a cytopathic strain of duck hepatitis B virus显示文摘 | Lenhoff RJ Luscombe CA Summers J | 1999 | Hepatology1999，29，： | 1 |
| 9 | Post-operative mortality related to wait-ing time for hip fracture surgery显示文摘 | Bansal R Luscombe J Cooper JP | 2004 | Injury2004，36，8： | 1 |
| 10 | Recognition and treatment of depression显示文摘 | Ye Rong Georgina M. Luscombe Tracey A. Davenport Yueqin Huang Nick Glozier Ian B. Hickie | 2009 | Social Psychiatry and Psychiatric Epidemiology2009，，8： | 1 |
| 11 | Diets high and low in glycemic index diets versus high monounsaturated fat diets:effects on glucose and lipid metabolism in NIDDM显示文摘 | LUSCOMBE N D NOAKES M CLIFTON P M | 1999 | Eur J Clin Nutr1999，53，： | 1 |
| 12 | The effect of chain length of heparin units interaction with lipoprotein lipase显示文摘 | CLARKE A R LUSCOMBE M HOLBROOK J J | 1983 | 747 : 1301983，747，： | 1 |
| 13 | The changing pattern of management for hormone-refractory, metastatic prostate cancer 显示文摘 | James ND Bloomfield D Luscombe C | 2006 | Prostate Cancer Prostatic Dis2006，9，： | 1 |
| 14 | Abdominal bloating:an under-recognized endometriosis symptom显示文摘 | Luscombe GM Markham R Judio M | 2009 | J Obstet Gynaecol Can2009，31，12： | 1 |
| 15 | What is bioinformatics? A proposed definition and overview of the field显示文摘 | Greenbaum D Gerstein M | 2001 | Methods Inf Med2001，40，4： | 1 |
| 16 | The three in one procedure:how I do it显示文摘 | Luscombe KL Maffulli N | 2005 | Surgeon2005，3，1： | 1 |
| 17 | Effect of a high-protein, energy-restricted diet on body composition, glycemic control, and lipid concentrations in overweight and obese hyperinsulinemic men and women显示文摘 | Famsworth E Luscombe N D Noakes M | 2003 | Am J Clin Nutr2003，78，1： | 1 |
| 18 | Protein-DNA interactions: amino acid conservation and the effects of mutations on binding specificity 显示文摘 | Luscombe N M Thomton J M | 2002 | J Mol Biol2002，320，5： | 1 |
| 19 | Post-operative mortality related to waiting time for hip fracture surgery显示文摘 | Bansal R Luscombe J Cooper JP | 2004 | Injury2004，35，2： | 1 |
| 20 | A randomised comparison of parecoxib versus placebo for pain management following minor day stay gynaecological surgery 显示文摘 | Luscombe KS McDonnell NJ Muchatuta NA | 2010 | Anaesth Intensive Care2010，38，1： | 1 |
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