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| 1 | Functional gastrointestinal disorders in eating disorder patients:Altered distribution and predictors using ROME Ⅲ compared to ROME Ⅱ criteria显示文摘AIM:To compare the prevalence of Functional gastrointestinal disorders(FGIDs)using ROMEⅢand ROMEⅡand to describe predictors of FGIDs among eating disorder(ED)patients.METHODS:Two similar cohorts of female ED inpatients,aged 17-50 years,with no organic gastrointestinal or systemic disorders,completed either the ROMEⅢ(n=100)or the ROMEⅡ(n=160)questionnaire on admission for ED treatment.The two ROME cohorts were compared on continuous demographic variables(e.g.,age,BMI)using Student’s t-tests,and on categorical variables(e.g.,ED diagnosis)usingχ2-tests.The relationship between ED diagnostic subtypes and FGID categories was explored usingχ2-tests.Age,BMI,and psychological and behavioural predictors of the common(prevalence greater than 20%)ROMEⅢFGIDs were tested using logistic regression analyses.RESULTS:The criteria for at least one FGID were fulfilled by 83%of the ROMEⅢcohort,and 94%of the ROMEⅡcohort.There were no significant differences in age,BMI,lowest ever BMI,ED diagnostic subtypes or ED-related quality of life(QOL)scores between ROMEⅡand ROMEⅢcohorts.The most prevalent FGIDs using ROMEⅢwere postprandial distress syndrome(PDS)(45%)and irritable bowel syndrome(IBS)(41%),followed by unspecified functional bowel disorders(U-FBD)(24%),and functional heartburn(FH)(22%).There was a 29%or 46%increase(depending on presence or absence of cyclic vomiting)in functional gastroduodenal disorders because of the introduction of PDS in ROMEⅢcompared to ROMEⅡ.There was a 35%decrease in functional bowel disorders(FBD)in RomeⅢ(excluding U-FBD)compared to ROMEⅡ.The most significant predictor of PDS was starvation(P=0.008).The predictor of FH(P=0.021)and U-FBD(P=0.007)was somatisation,and of IBS laxative use(P=0.025).Age and BMI were not significant predictors.The addition of the 6-mo duration of symptoms requirement for a diagnosis in ROMEⅢadded precision to many FGIDs.CONCLUSION:ROMEⅢconfers higher precision in diagnosing FGIDs but self-induced vomiting should be excluded from the diagnosis of cyclic vomiting.Psychological factors appear to be more influential in ROMEⅡthan ROMEⅢ. | Xiaojie Wang Georgina M Luscombe Catherine Boyd John Kellow Suzanne Abraham | 2014 | World Journal of Gastroenterology2014，20，43： | 4 |
| 2 | A randomised comparison of parecoxib versus placebo for pain management following minor day stay gynaecological surgery显示文摘 | Luscombe K S McDonnell N J Muchatuta N A Paech M J Nathan E A | 2010 | Anaesthesia and Intensive Care2010，，1： | 2 |
| 3 | A study of some variables in a tetrazolium dye(MTT)based assay for cell growth and chemosensitivity显示文摘 | Twentyman PR Luscombe M | | 0，，： | 1 |
| 4 | Use of 14C l-sodium bicarbonate/urea to measure total energy expenditure in overweight men and women before and after low calorie diet induced weight loss 显示文摘 | Luscombe ND Tsopelas C Bellon M | 2006 | Asia Pac 3 Clin Nutr2006，15，3： | 1 |
| 5 | Diets high and low in glycemic index diets versus high monounsaturated fat diets:effects on glucose and lipid metabolism in NIDDM显示文摘 | LUSCOMBE N D NOAKES M CLIFTON P M | 1999 | Eur J Clin Nutr1999，53，： | 1 |
| 6 | The effect of chain length of heparin units interaction with lipoprotein lipase显示文摘 | CLARKE A R LUSCOMBE M HOLBROOK J J | 1983 | 747 : 1301983，747，： | 1 |
| 7 | Abdominal bloating:an under-recognized endometriosis symptom显示文摘 | Luscombe GM Markham R Judio M | 2009 | J Obstet Gynaecol Can2009，31，12： | 1 |
| 8 | What is bioinformatics? A proposed definition and overview of the field显示文摘 | Greenbaum D Gerstein M | 2001 | Methods Inf Med2001，40，4： | 1 |
| 9 | Effect of a high-protein, energy-restricted diet on body composition, glycemic control, and lipid concentrations in overweight and obese hyperinsulinemic men and women显示文摘 | Famsworth E Luscombe N D Noakes M | 2003 | Am J Clin Nutr2003，78，1： | 1 |
| 10 | Protein-DNA interactions: amino acid conservation and the effects of mutations on binding specificity 显示文摘 | Luscombe N M Thomton J M | 2002 | J Mol Biol2002，320，5： | 1 |
| 11 | All-inkjet-printed flexible electronics fabrication on a polymer substrate by low-temperature high-resolution selective laser sintering of metal nanoparti-cles显示文摘 | Ko S H Pan H Grigoropoulos C P Luscombe C K Frechet J M J Poulikakos D | 2007 | Nanotechnology2007，18，34： | 1 |
| 12 | The use of tissue plasminogen activator as continuous infusion into an arteri- ovenous hemodialysis access in the hemodialysis unit: a case series显示文摘 | van der Merwe E Luscombe R Kiaii M | 2015 | Can J Kidney Health Dis2015，2，： | 1 |
| 13 | Protein family and fold occurrence in genomes:Power-law behaviour and evolutionary model显示文摘 | QIAN J LUSCOMBE N M GERSTEIN M | 2001 | J Mol Biol2001，313，4： | 1 |
| 14 | A preli- minary study of aged care facility staff indicates limita- tions in awareness of the link between depression and physical morbidity显示文摘 | Atkins J Naismith S L Luscombe G M | 2013 | BMC Geriatrics2013，9，： | 1 |
| 15 | A study of some variables in a tet- razolium dye(MTT) bassed assay for cell growth and chemosensi- tivity 显示文摘 | Twentyman PR Luscombe M | 1987 | BRJ Cancer1987，56，3： | 1 |
| 16 | Structure and evo- lution of transcriptional regulatory networks 显示文摘 | Babu M M Luscombe N M Aravind L | 2004 | Curr Opin in Struc Biol2004，14，： | 1 |
| 17 | Ghrelin and Measures of Satiety Are Altered in Polycystic Ovary Syndrome But Not Differentially Affected by Diet Composition显示文摘 | L J. Moran M Noakes P M. Clifton G A. Wittert L Tomlinson C Galletly N D. Luscombe R J. Norman | 2004 | The Journal of Clinical Endocrinology & Metabolism2004，，7： | 1 |
| 18 | Genomic analysis of geneexpression relationships in transcriptional regulatory networks显示文摘 | Yu H Y Luscombe N M Qian J | 2003 | Trends in Genetics2003，19，8： | 1 |
| 19 | Effect of a high protein, energy restricted diet on body composition, glycaemic control, and lipid concentrations in overweight and obese hyperinsulinemic men and women显示文摘 | Farnsworth E Luscombe ND Noakes M | 2003 | Am J Clin Nutr2003，78，1： | 1 |
| 20 | Nucleic Acids Research 显示文摘 | Luscombe N M Laskowski R A Thornton J M | 2001 | 29(13): 2860-28742001，29，13： | 1 |
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