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| 1 | Role of the HLA-DQ locus in the development of chronic gastritis and gastric carcinoma in Mexican patients显示文摘AIM: To determine the HLA-DQ locus in Mexican patients with Chronic gastritis and gastric adenocarcinoma. METHODS: Oligotyping for HLA-DQ locus was performed in 45 Mexican patients with chronic gastritis and 13 Mexican patients with diffuse-type gastric adenocarcinoma, and was then compared with 99 clinically healthy unrelated individuals. H pylori infection and CagA status were assessed in patients by enzyme-linked immunosor-bent assay (ELISA) method. RESULTS: We found a significant increased frequency of HLA-DQB1*0401 allele in H pylori-positive patients with chronic gastritis when compared with healthy subjects [19 vs 0%, P= 1 × 10-7, odds ratio (OR) = 4.96; 95% confidence interval (95% CI), 3.87-6.35]. We also found a significant increased frequency of HLA-DQB1*0501 in patients with diffuse-type gastric carcinoma in comparison with healthy individuals (P = 1 × 10-6, OR = 13.07; 95% CI, 2.82-85.14). CONCLUSION: HLA-DQ locus may play a different role in the development of H pylori-related chronic gastritis and diffuse-type gastric adenocarcinoma in the Mexican Mestizo population. | Roberto Herrera-Goepfert Jesús K Yamamoto-Furusho Luis F Oate-Ocaa Margarita Camorlinga-Ponce Leopoldo Muoz Jorge A Ruiz-Morales Gilberto Vargas-Alarcón Julio Granados Cellular Biology Section | 2006 | World Journal of Gastroenterology2006，12，48： | 4 |
| 2 | A family study of endophenotypes for psychosis within an early intervention programme in Hong Kong: Rationale and preliminary findings显示文摘The study of endophenotypes may be a viable strategy to tackle the genetic complexity and phenotypic heterogeneity of psychosis, but this research direction is relatively under-developed in China as compared to Western countries. We have recently initiated one of the first family studies of endophenotypes for psychosis in China. Patients entering an established early psychosis intervention service are recruited into this research project for phenotyping, endophenotyping and genotyping. At the endophenotypic level, four domains (neurological soft signs, neurocognition of prospective memory, social cognition of facial emotion recognition, and affective cognition of anticipatory and consummatory pleasure) are studied in the sample of patients with psychosis and their unaffected siblings. This article illustrates the benefit of a research-oriented clinical programme and its findings based on the data collected as of early 2011. | LUI Simon S Y SHAM Pak CHAN Raymond C K CHEUNG Eric F C | 2011 | Chinese Science Bulletin2011，56，32： | 2 |
| 3 | Prokineticin-1 (Prok-1) works coordinately with glial cell line derived neurotrophic factor (GDNF) to mediate proliferation and differentiation of enteric neural crest cells显示文摘 | Ngan E S Shum C K Poon H C Sham M H Garcia-Barcelo M M Lui V C | 2008 | Biochim Biophys Acta2008，1783，： | 1 |
| 4 | Coding-and interference-aware routing protocol in wireless networks显示文摘 | HOU R QU S LUI K S | 2013 | Computer Communica- tions2013，36，17： | 1 |
| 5 | On perimeter coverage in wireless sensor networks显示文摘 | Hung K S Lui K S | 2010 | IEEE Transactions on Wireless Communications2010，9，7： | 1 |
| 6 | Increased alpha-B-crystallin expression in mammary metaplastic carcinomas 显示文摘 | Chan S K Lui P C Tan P H | 2011 | Histopatholo- gy2011，59，2： | 1 |
| 7 | Finite element analysis of the influence of tool edge radius on size effect in orthogonal micro-cutting process 显示文摘 | Lui K Melkote S N | 2007 | Int J Mech Sci (S0020-7403)2007，49，5： | 1 |
| 8 | Nature of the Acceptor Responsible for p-Type Conduction in Liquid Encapsulated Czochralski-Grown Undoped Gallium Antimonide显示文摘 | Ling C C Lui M K Ma S K | 2004 | Appl Phys Lett2004，85，： | 1 |
| 9 | SmaB-world overlay P2P networks: construction, management and handling of dynamic flash crowds显示文摘 | Hui Ken Y K Lui John C S Yan David K Y | 2006 | Computer Networks2006，50，15： | 1 |
| 10 | Routing with topology aggregation in delay-bandwidth sensitive networks显示文摘 | Lui K S Nahrstedt K Chen S | | 0，，01： | 1 |
| 11 | Aptamer-mediated inhibition of Mycobacterium tuberculosis polyphosphate kinase 2显示文摘 | Shum K T Lui E L Wong S C Yeung P Sam L Wang Y | | 0，，： | 1 |
| 12 | Prelmiinary study on cardiotoxicity of celastrol to zebrafish embryo显示文摘 | Wang S W Lui K C W ang X M | 2009 | Chin Pharm- Bull2009，25，5： | 1 |
| 13 | Electron Irradiated Liquid Encapsulated Czochralski Grown Undoped Gallium Antimonide Studied by Positron Lifetime Spectroscopy and Photoluminescence显示文摘 | Ma S K Lui M K Ling C C | 2004 | J Phys:Condens Matter2004，16，： | 1 |
| 14 | Bioactivity and corrosion properties of novel coatings containing strontium by mi-cro-arc oxidation显示文摘 | Kung K C Lee T M Lui T S | 2010 | Journal of Alloys and Compounds2010，508，： | 1 |
| 15 | Analysis of gas foil bearings integ-rating FE top foil models 显示文摘 | Luis S A Tae H K | 2009 | Tribology International2009，42，： | 1 |
| 16 | Spatial structure of the thermal bound- ary layer in turbulent convection显示文摘 | Lui S L Xia K Q | | 0，，： | 1 |
| 17 | Routing with topology aggregation in delay-bandwidth sensitive networks显示文摘 | LUI K L NAHRSTEDT K CHEN S G | 2004 | IEEE/ACM Transaction on Networking2004，12，1： | 1 |
| 18 | Self - Reported Sleep and Nap Habits and Risk of Fails and Fractures in Older Women:The Study of Osteoporotic Fractures 显示文摘 | Stone K L Ewing S K Lui L Y | 2006 | Journal of the American Geriat- rics Society2006，54，8： | 1 |
| 19 | Clinical significance of microscopic tumor venous invasion in patients with resectable hepatocellular carcinoma显示文摘 | Tsai T J Chau G Y Lui W Y Tsay S H King K L Loong C C | 2000 | Surgery2000，127，： | 1 |
| 20 | Small-world overylay P2P networks:construction,management and handling of dynamic flash crowds显示文摘 | Hui K Y K Lui J C S Yau D K Y | 2006 | Computer Networks2006，50，15： | 1 |
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