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| 1 | An Evolutionary Approach to the Delineation of Functional Areas Based on Travel-to-work Flows显示文摘This paper presents a new approach to the delineation of local labor markets based on evolutionary computation.The aim of the exercise is the division of a given territory into functional regions based on travel-to-work flows.Such regions are defined so that a high degree of inter-regional separation and of intra-regional integration in both cases in terms of commuting flows is guaranteed. Additional requirements include the absence of overlap between delineated regions and the exhaustive coverage of the whole territory. The procedure is based on the maximization of a fitness function that measures aggregate intra-region interaction under constraints of inter-region separation and minimum size.In the experimentation stage,two variations of the fitness function are used,and the process is also applied as a final stage for the optimization of the results from one of the most successful existing methods,which are used by the British authorities for the delineation of travel-to-work areas(TTWAs).The empirical exercise is conducted using real data for a sufficiently large territory that is considered to be representative given the density and variety of travel-to-work patterns that it embraces.The paper includes the quantitative comparison with alternative traditional methods,the assessment of the performance of the set of operators which has been specifically designed to handle the regionalization problem and the evaluation of the convergence process.The robustness of the solutions,something crucial in a research and policy-making context,is also discussed in the paper. | Francisco Flórez-Revuelta JoséManuel Casado-Díaz Lucas Martínez-Bernabeu | 2008 | International Journal of Automation and computing2008，5，1： | 2 |
| 2 | Acute kidney injury and electrolyte disorders in COVID-19显示文摘Acute kidney injury(AKI)and electrolyte disorders are important complications of hospitalized coronavirus disease 2019(COVID-19)patients.AKI is thought to occur due to multiple pathophysiological mechanisms,such as multiple organ dysfunction(mainly cardiac and respiratory),direct viral entry in the renal tubules,and cytokine release syndrome.AKI is present in approximately one in every ten hospitalized COVID-19 patients.The incidence rates of AKI increase in patients who are admitted to the intensive care unit(ICU),with levels higher than 50%.Additionally,renal replacement therapy(RRT)is used in 7%of all AKI cases,but in nearly 20%of patients admitted to an ICU.COVID-19 patients with AKI are considered moderate-to-severe cases and are managed with multiple interdisciplinary conducts.AKI acts as a risk factor for mortality in severe acute respiratory syndrome coronavirus 2 infection,especially when RRT is needed.Electrolyte disorders are also common manifestations in hospitalized COVID-19 patients,mainly hyponatremia,hypokalemia,and hypocalcemia.Hyponatremia occurs due to a combination of syndrome of inappropriate secretion of antidiuretic hormone and gastrointestinal fluid loss from vomiting and diarrhea.When it comes to hypokalemia,its mechanism is not fully understood but may derive from hyperaldosteronism due to renin angiotensin aldosterone system overstimulation and gastrointestinal fluid loss as well.The clinical features of hypokalemia in COVID-19 are similar to those in other conditions.Hypocalcemia is the most common electrolyte disorder in COVID-19 and seems to occur because of vitamin D deficiency and parathyroid imbalance.It is also highly associated with longer hospital and ICU stay. | Gabriel Martins Nogueira Noel Lucas Oliveira Rodrigues Silva Ana Flávia Moura Marcelo Augusto Duarte Silveira JoséA Moura-Neto | 2022 | World Journal of Virology2022，11，5： | 2 |
| 3 | Variation in carotid endarterectomy mortality in the Medicare population: trial hospitals, volume, and patient characteristics 显示文摘 | Wennberg DE Lucas FL Birkmeyer JD | 1998 | JAMA1998，279，： | 1 |
| 4 | Preterm premature rupture of membranes >/= 32 weeks' gestation: impact of revised practice guidelines 显示文摘 | FAKSH A WAX JR LUCAS FL | 2011 | Am J Obstetrics Gynecol2011，205，4： | 1 |
| 5 | Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease 显示文摘 | Oberg BP McMenamin E Lucas FL | 2004 | Kidney Int2004，65，3： | 1 |
| 6 | Increased preva- lence of oxidant stress and inflammation in patients with mod- erate to severe chronic kidney disease显示文摘 | Oberg BP Mcmenamin E Lucas FL | 2004 | Kidney Int2004，65，3： | 1 |
| 7 | Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease显示文摘 | Oberg BP McMenamin E Lucas FL | 2004 | Kidney Int2004，65，3： | 1 |
| 8 | Increased prevalence of oxidant stress and inflammation in patients with moderate tosevere chronic kidney disease显示文摘 | Oberg BP McMenamin E Lucas FL | 2004 | Kidney Int2004，65，3： | 1 |
| 9 | Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease 显示文摘 | Oberg BP McMenamin E Lucas FL | 2004 | Kidney Int2004，65，3： | 1 |
| 10 | Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease显示文摘 | Oderg BP Memenamin E Lucas FL | 2004 | Kidney Int2004，65，： | 1 |
| 11 | Increased prevalence of oxi -dant stress and inflammation in patients with moderate to se- vere chronic kidney disease显示文摘 | Oberg BP Mc ME Lucas FL | 2004 | Kidney Int2004，65，3： | 1 |
| 12 | Increased prevalence of oxi- dant stress and inflammation in patients with moderate to severe chronic kidney disease显示文摘 | Oderg BP Memenamin E Lucas FL | 2004 | Kidney Int2004，65，3： | 1 |
| 13 | Increased prevalence of oxi- dant stress and inflammation in patients with moderate to severe chronic kidney disease 显示文摘 | Oberg BP Mc Menamin E Lucas FL | 2004 | Kidney Int2004，65，3： | 1 |
| 14 | Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease显示文摘 | Oberg BP Momenamin E Lucas FL | | 0，，03： | 1 |
| 15 | Survival after open ver- sus endovascular thoracic aortic aneurysm repair in an observa- tional study of the Medicare population 显示文摘 | Goodney PP Travis L Lucas FL | 2011 | Circulation2011，124，24： | 1 |
| 16 | Increased prevalence of oxidant stress,and inflammation in patients with moderate to severe chronic kidney disease显示文摘 | Oberg BP McMenamin E Lucas FL | 2004 | Kidney Int2004，65，3： | 1 |
| 17 | Increased prevalence ofoxidant stress and inflammation in patients with moderate to severechronic kidney disease显示文摘 | Oberg BP McMenamin E Lucas FL | 2004 | Kidney Int2004，65，3： | 1 |
| 18 | Should volume standards for cardiovascular surgery focus only on high-risk patients显示文摘 | Goodney PP Lucas FL Birkmeyer JD | | 0，，： | 1 |
| 19 | Should volume standards for cardiovascular surgery focus only on high-risk patients? 显示文摘 | Goodney PP Lucas FL Birkmeyer JD | 2003 | Circulation2003，107，3： | 1 |
| 20 | Hospital volume,length of stay and readmission rates in high-risk surgery显示文摘 | Goodney PP Stukel TA Lucas FL | 2003 | Ann Surg2003，238，： | 1 |
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