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| 1 | Analysis of the Genetic Diversity of Natural Populations of Alpinia oxyphylla Miquel Using Inter-Simple Sequence Repeat Markers显示文摘 | Wang Haiyan Liu Xiaojing Wen Mingfu Pan Kun Zou Meiling Lu Cheng Liu Shisheng Wang Wenquan | 2012 | EN2012，，4： | 2 |
| 2 | Co-seismic energy release and relevant region of Tohoku M9.0 earthquake显示文摘'Off the Pacific coast of Tohoku Earthquake' (M9.0,on March 11th,2011) is the greatest one in Japanese seismic record. The hypocenter is located 130 km ESE off the Pacific coast of Tohoku with the focal depth of 24 km. | LU MingFu LI Li XIA MengFen WANG HaiYing BAI YiLong1 | 2011 | Science China Earth Sciences2011，54，7： | 2 |
| 3 | Spontaneous movement of a retrotransposon generated genic dominant male sterility providing a useful tool for rice breeding显示文摘Male sterility in plants provides valuable breeding tools in germplasm innovation and hybrid crop production.However,genetic resources for dominant genic male sterility,which hold great promise to facilitate breeding processes,are extremely rare in natural germplasm.Here we characterized the Sanming Dominant Genic Male Sterility in rice and identified the gene SDGMS using a map-based cloning approach.We found that spontaneous movement of a 1978-bp long terminal repeat(LTR)retrotransposon into the promoter region of the SDGMS gene activates its expression in anther tapetum,which causes abnormal programmed cell death of tapetal cells resulting in dominant male sterility.SDGMS encodes a ribosome inactivating protein showing N-glycosidase activity.The activation of SDGMS triggers transcription reprogramming of genes responsive to biotic stress leading to a hypersensitive response which causes sterility.The results demonstrate that an ectopic gene activation by transposon movement can give birth to a novel trait which enriches phenotypic diversity with practical utility. | Conghao Xu Yifeng Xu Zhengji Wang Xiaoyu Zhang Yuying Wu Xinyan Lu Hongwei Sun Lei Wang Qinglu Zhang Qinghua Zhang Xianghua Li Jinghua Xiao Xu Li Mingfu Zhao Yidan Ouyang Xianbo Huang Qifa Zhang | 2023 | National Science Review2023，10，9： | 1 |
| 4 | Study on poly(propylene)/ammonium polyphosphate composites modified by ethylene-1-octene copolymer grafted with glycidyl methacrylate显示文摘 | Zhang Shijun Yu Dingsheng | 2004 | J Appl Poly Sci2004，93，1： | 1 |
| 5 | Study on poly ( propylene)/ammonium polyphosphate composites modified by ethylene - 1 - octene copolymer grafted with glycidyl methacrylateon poly( propylene)/ammonium polyphosphate composites modified by ethylene - 1 - octene copolymer grafted with glycidyl methacrylate 显示文摘 | LU MINGFU ZHANG SHIJUN YU DINGSHENG | 2004 | Journal of Applied Polymer Science2004，93，1： | 1 |
| 6 | NIR-Ⅱ fluorescence/photoacoustic imaging of ovarian cancer and peritoneal metastasis显示文摘Ovarian cancer is a global problem,and is typically diagnosed in the middle or late stages,with a mysterious abdominal mass or atypical abdominal metastases due to the lack of specific initial diagnostic methods.Dual-modal near-infrared Ⅱ(NIR-Ⅱ,1,000–1,700 nm)fluorescence/photoacoustic imaging has great potential in early ovarian cancer diagnosis and image-guided surgery due to its high sensitivity and deep penetration.Herein,we report a novel organic NIR-Ⅱ dye(H10)with excellent aggregation-induced-emission(AIE)characteristics(I/I0>1.6)utilizing a selenadiazolo-[3,4-f]benzo[c][1,2,5]thiadiazole(ST)-based building block.Then,water-soluble and biocompatible H10@follicle-stimulating hormone(H10@FSH)dots with superior optical/photoacoustic properties and a tenfold increase in ovarian-specific targeting ability were synthesized.Finally,for the first time,in vivo dual-mode NIR-Ⅱ fluorescent/photoacoustic(PA)imaging and image-guided surgery of patient-derived tumor xenograft(PDTX)and micro-metastatic abdominal ovarian cancer lesions were investigated.This novel strategy will establish a new method for early detection of ovarian cancer and significantly improve the prognosis of ovarian cancer patients. | Siyu Lu Liru Xue Meng Yang Jingjing Wang Yang Li Yuxin Jiang Xuechuan Hong Mingfu Wu Yuling Xiao | 2022 | Nano Research2022，15，10： | 0 |
| 7 | Mobile person re-identification with a lightweight trident CNN显示文摘Dear editor,Person re-identification(re-ID)aims to recognize or associate a person and time at non-overlapping physical locations after the person had been previously observed visually elsewhere.This technology is considered increasingly important in sustaining social security for smart cities[1]. | Mingfu XIONG Dan CHEN Xiaoqiang LU | 2020 | Science China(Information Sciences)2020，63，11： | 0 |
| 8 | Inhibitory Effects of Cordyceps militaris( Bombyx mori )Extract against Respiratory Syncytial Virus显示文摘[Objective] This study aimed to investigate the inhibitory effects of 95%,70% ethanol extracts and water extract of Cordyceps militaris( Bombyx mori). on cells infected with respiratory syncytial virus( RSV).[Method] Human embryonic kidney cells( HEK293,RSV virus-sensitive cells) were infected with respiratory syncytial virus and incubated with tissue cell culture method,to analyze the inhibitory effects of different extracts of Cordyceps militaris( Bombyx mori) on proliferation of RSV-infected cells by cytopathic effect( CPE) observation and tetrazolium salt reduction assay( MTT method).[Result]Different extracts of Cordyceps militaris( Bombyx mori) were non-toxic to HEK293 cells. CPE occurred successively in various sample groups after 48 h,and the degree of CPE was reduced gradually with the increasing concentration. To be specific,95% ethanol extract(100 μg / ml),70% ethanol extract(100,25 μg / ml) and water extract(100,25 μg/ml) of Cordyceps militaris(Bombyx mori) exhibited inhibitory effects against RSV subtype A; 70% ethanol extract(100,25 μg/ml) and water extract(100,25 μg / ml) of Cordyceps militaris( Bombyx mori) exhibited inhibitory effects against RSV subtype B; the effects of water extract(100 μg / ml) of Cordyceps militaris( Bombyx mori) on RSV subtypes A and B were similar to positive control group. However,different extracts of Cordyceps militaris( Bombyx mori) with low concentrations(6. 25,1. 56 μg / ml) exhibited no inhibitory effects against respiratory syncytial virus. [Conclusion] Cordyceps militaris( Bombyx mori) exhibited significant inhibitory effects against syncytial virus,and the inhibitory effects were related to the water soluble components. | Min WEI Shengzhi ZHENG Cuiping JIANG Mingfu XIAO Ye LU | 2015 | Agricultural Biotechnology2015，4，1： | 0 |
| 9 | Activation of NLRP3 Inflammasome via Drp1 Overexpression in Kupffer Cells Aggravates Ischemia-reperfusion Injury in Hepatic Steatosis显示文摘Background and Aims:Donors with fatty livers are considered to address the shortage of livers for transplantation,but those livers are particularly sensitive to ischemia-reperfusion injury(IRI),and an increased incidence of graft failure is observed.Kupffer cells account for 20–35%of liver nonparenchymal cells,and have been shown to participate in the process of IRI and inflammatory reactions of hepatic steatosis.NOD-like receptor thermal protein domain-associated protein 3(NLRP3)is an intracellular sensor activated by Kupffer cells to promote generation and participates in IRI.Dynamics-associated protein 1(Drp1)is one of the main proteins regulating mitochondrial division and exacerbates IRI by affecting mitochondrial dynamics.The mechanism of interaction of Kupffer cells with Drp1 and NLRP3 to aggravate IRI has not been clarified.Methods:A mouse model of hepatic steatosis was established by feeding the mice with a high-fat diet.In vitro experiments were performed using AML12 normal mouse liver cells and RAW264.7 mononuclear macrophage cells cultured in medium with palmitate and oleic acid.Western blotting and immunohistochemical(IHC)staining were used to detect the expression of NLRPP3 and Drp1 in IRI in the control and high-fat diet groups.The expression of F4/80+cells during IRI in hepatic steatosis was verified by IHC staining,and the role of NLRPP3 and Drp1 in Kupffer-cell mediated IRI was investigated by targeting Drp-1 inhibition.Results:Drp1 and NLRP3 expression was increased during IRI in hepatic steatosis,and the expression of Drp1 and NLRP3 were decreased after the elimination of Kupffer cells.That indicated Kupffer cells were involved in the process of IRI in hepatic steatosis through the action of Drp1 and NLRP3.After Drp1 inhibition,liver function was restored and NLRP3 expression level was reduced.Conclusions:Kupffer cells aggravated IRI in hepatic steatosis via NLRP3 and Drp1.Drp1 inhibitors might be useful as specific therapeutics to alleviate IRI in hepatic steatosis and may have promise in case of liver donor shortage. | Lu Zhang Mingfu Wang Ran An Jun Dai Shujun Liu Ming Chen Haoran Ding | 2023 | Journal of Clinical and Translational Hepatology2023，11，5： | 0 |
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