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| 1 | 血管性认知损害诊断的进一步规范化:血管性认知损害分类共识研究组指南显示文摘引言血管性认知损害(vascular cognitive impairment,VCI)诊断共识的缺乏(体现为多种不同评估方案的使用),妨碍了对其理解和治疗的推进.多个国家的大量临床医生和研究人员参与了2个阶段血管性认知损害分类共识研究(Vascular Impairment of Cognition Classification Consensus Study,VICCCS),旨在就VCI的诊断原则(VICCCS-1)和诊断方案(VICCCS-2)达成一致意见.本文提供了VICCCS-2的相关内容.方法使用VICCCS-1达成的原则和已发表的诊断指南作为在线德尔菲(Delphi)调查的参考基点,以期对VCI的临床诊断达成共识.结果共进行了6轮调查,每轮有65~79名专家参与,他们就VICCCS修订的轻度和重度VCI的诊断指南达成共识,并肯定了美国国立神经疾病与卒中研究所-加拿大卒中网(National Institute of Neurological Disorders and Stroke–Canadian Stroke Network,NINDS-CSN)发布的神经心理学评估方案和对影像学检查的推荐意见.讨论VICCCS-2建议规范化应用NINDS-CSN推荐的神经心理学和影像学评估方案诊断VCI,以促进研究协作. | Olivia A. Skrobot Sandra E. Black Christopher Chen Charles DeCarli Timo Erkinjuntti Gary A. Ford Rajesh N. Kalaria John O'Brien Leonardo Pantoni Florence Pasquier Gustavo C. Roman Anders Wallin Perminder Sachdev Ingmar Skoog the VICCCS group Yoav Ben-Shlomo Anthony P. Passmore Seth Love Patrick G. Kehoe 朱婷珂 徐俊 | 2018 | 国际脑血管病杂志2018，26，4： | 58 |
| 2 | Validation of Zebrafish (Danio rerio) Reference Genes for Quantitative Real-time RT-PCR Normalization显示文摘The normalization of quantitative real time RT-PCR (qRT-PCR) is important to obtain accurate gene expression data. The most common method for qRT-PCR normalization is to use reference, or house- keeping genes. However, there is emerging evidence that even reference genes can be regulated under different conditions, qRT-PCR has only recently been used in terms of zebrafish gene expression studies and there is no validated set of reference genes. This study characterizes the expression of nine possible reference genes during zebrafish embryonic development and in a zebrafish tissue panel. All nine reference genes exhibited variable expression. The β-actin, EF1α and Rp113α genes comprise a validated reference gene panel for zebrafish developmental time course studies, and the EF1α, Rp113α and 18S rRNA genes are more suitable as a reference gene panel for zebrafish tissue analysis. Importantly, the zebrafish GAPDH gene appears unsuitable as reference gene for both types of studies. | Rongying TANG Andrew DODD Daniel LAI Warren C. MCNABB Donald R. LOVE | 2007 | Acta Biochimica et Biophysica Sinica2007，39，5： | 31 |
| 3 | Nat Methods:新型计算方法或能更加精准地分析基因表达状况显示文摘日前,一项刊登在国际杂志NaCre Methods上的研究报告中,来自美国卡内基梅隆大学等机构的研究人员通过研究开发了一种新型的计算方法,该方法能够有效改善对基因表达分析的准确性。研究人员或有望利用该方法来诊断并且监测癌症。同时或许也能够促进基础生物学的研究进展。 | Rob Patro Geet Duggal Michael I Love Rafael A Irizarry Michael I Love Rafael A Irizarry Carl Kingsford | 2017 | 现代生物医学进展2017，17，11： | 30 |
| 4 | 国外肺通气功能指标预计值在我国北方地区的适用性显示文摘目的 研究国外肺通气功能指标预计值在我国北方地区的适用性。方法 通过对 2 82 5名受检者肺通气功能指标的分析 ,比较中国东北与国外预计值公式的预计值、实测值 /预计值、肺功能指标异常率。结果 证实中国东北预计值公式计算的男性用力肺活量 (FVC)、 1秒钟用力肺活量占用力肺活量比值 (FEV1 0 %)预计值较国外预计值公式计算的数值偏高 ,1秒钟用力呼气量 (FEV1 0 )偏低 ,且差异有显著性 (P <0 0 5 ) ;女性的FVC、FEV1 0 和FEV1 0 %预计值偏高 ,且FEV1 0 和FEV1 0 %差异有显著性 (P <0 0 5 )。中国东北预计值公式计算的男性FVC和FEV1 0 %的实测值 /预计值较国外预计值公式计算的数值偏低 ,而FEV1 0 偏高 (P <0 0 5 )。如果采用国外预计值公式 ,将导致判断FVC和FEV1 0 %为“异常”的病例数减少 ,而FEV1 0 “异常”的病例数增多 ;采用中国东北预计值公式计算女性FVC、FEV1 0 和FEV1 0 %的实测值 /预计值较国外公式计算的数值均偏低 ,如采用国外预计值公式 ,将使女性肺功能判定为“异常”的例数减少。结论 建议在使用装有预计值的进口肺功能测定仪时 。 | 吴永会 张忠义 那常筠 林磊光 卢卓扬 E.J Love | 2003 | 工业卫生与职业病2003，29，2： | 11 |
| 5 | 高含硫气井安全高效钻完井配套技术--以川东北罗家寨气田为例显示文摘四川盆地东北部罗家寨气田具有高含H_2S、高压、高产等特点,钻井过程中面临喷、漏、塌、卡、斜、硬、毒等难题。为此,以高含硫气井安全高效钻完井为目标,将目前先进的钻完井工艺技术进行了技术集成应用;按照国际一流水准的HSE管理体系要求,充分利用JSA、BBS卡、PTW、SWA、上锁挂签等安全工具.对各个专业化施工单位进行安全、环境及质量的全过程受控管理,真正做到界面清晰、衔接有序、高效运作。现场应用效果表明:①合成基钻井液完全满足本区域高含硫气井钻井要求;②PDC+旋转导向+随钻测井测斜+循环堵漏短节配套井下工具能满足高钻速、井眼轨迹优质、精控钻井液密度、及时应对堵漏等要求,且能钻达固井井深即可下套管;③采用封隔式尾管悬挂器为主体的防气窜配套工艺技术,配合使用弹性水泥浆体系,成功解决了喇叭口窜气问题,完全满足了后续作业对井筒完整性的要求;④LJ20井钻井周期较该气田平均钻井周期缩短了20%,平均机械钻速提高了41%.创造了该地区钻井的新纪录。所形成的钻完井配套技术可以有效地指导类似地区高含硫气田的安全高效开发。 | 张俊良 文绍牧 邵勇 雷震中 Tracy Love | 2015 | 天然气工业2015，35，4： | 10 |
| 6 | Classification of Subtype of Acute Ischemic Stroke: Definitions for Use in a Multicenter Clinical Trial显示文摘 | Harold P. Adams Birgitte H. Bendixen L. Jaap Kappelle José Biller Betsy B. Love David Lee Gordon E. Eugene Marsh | 1993 | Stroke1993，，1： | 9 |
| 7 | Cardiac adipose tissue and its relationship to diabetes mellitus and cardiovascular disease显示文摘Type-2 diabetes mellitus(T2DM) plays a central role in the development of cardiovascular disease(CVD). However, its relationship to epicardial adipose tissue(EAT) and pericardial adipose tissue(PAT) in particular is important in the pathophysiology of coronary artery disease. Owing to its close proximity to the heart and coronary vasculature, EAT exerts a direct metabolic impact by secreting proinflammatory adipokines and free fatty acids, which promote CVD locally. In this review, we have discussed the relationship between T2 DM and cardiac fat deposits, particularly EAT and PAT, which together exert a big impact on the cardiovascular health. | Adam M Noyes Kirandeep Dua Ramprakash Devadoss Lovely Chhabra | 2014 | World Journal of Diabetes2014，5，6： | 8 |
| 8 | 围手术期液体管理与发生术后肠麻痹的潜在关系显示文摘目的:结直肠手术后出现肠麻痹仍是外科医生所面临的难题,它延迟了患者的康复进度并增加了住院时间和住院费用。该研究的目的是在充分、有效地实施加速康复路径的基础上,探讨围手术期液体管理对结直肠手术后发生肠麻痹的影响。方法:这是一项基于公共数据库中前瞻性记录数据的回顾性队列研究。在整个研究期间,该医学中心全面实施标准化的加速康复路径。研究纳入2011-2016年连续收治的、患有良性或恶性肿瘤而接受结直肠切除手术的所有患者。术后肠麻痹(POI)的定义为需重新置入鼻胃管。本研究比较了术后有和无肠麻痹患者的围手术期液体管理和手术学结果。通过多因素Logistic回归分析判断影响患者肠麻痹的潜在危险因素。 | 卓长华 GRASS F LOVELY J K CRIPPA J | 2020 | 结直肠肛门外科2020，26，1： | 7 |
| 9 | Financial development and dynamic investment behavior: Evidence from panel VAR显示文摘 | Inessa Love Lea Zicchino | 2006 | Quarterly Review of Economics and Finance2006，，2： | 4 |
| 10 | Fecal lactoferrin accurately reflects mucosal inflammation in inflammatory bowel disease显示文摘BACKGROUND Studies have demonstrated a potential role for fecal biomarkers such as fecal calprotectin(FC)and fecal lactoferrin(FL)in monitoring inflammatory bowel diseases(IBD)-Crohn's disease(CD)and ulcerative colitis(UC).However,their correlation to endoscopic scores,disease severity and affected intestinal surface has not been extensively investigated.AIM To correlate FL,and for comparison white blood cell(WBC)and C-reactive protein(CRP),with endoscopic scores,disease extent and location in CD and UC.METHODS Retrospective analysis in 188 patients who had FL,CRP and WBC determined within 30 d of endoscopy.Disease location,disease extent(number of intestinal segments involved),disease severity(determined by endoscopic scores),timing of FL testing in relation to colonoscopy,as well as the use of effective fast acting medications(steroids and biologics)between colonoscopy and FL measurement,were recorded.RESULTS In 131 CD and 57 UC patients,both CRP and FL-but not WBC-distinguished disease severity(inactive,mild,moderate,severe).In patients receiving fastacting(steroids or biologics)treatment in between FL and colonoscopy,FL showed a higher correlation to endoscopic scores when tested before vs after the procedure(r=0.596,P<0.001,vs r=0.285,P=0.15 for the Simple Endoscopic Score for CD;and r=0.402,P=0.01 vs r=0.054 P=0.84 for Disease Activity Index).Finally,FL was significantly correlated with the diseased mucosal surface(colon-ileocolon>small bowel)and the number of inflamed colon segments.CONCLUSION FL and CRP separated disease severity categories with FL showing lower discriminating P-values.FL showed a close correlation with the involved mucosal surface and with disease extent and was more closely correlated to endoscopy when determined before the procedure–this indicating that inflammatory activity changes associated with therapy might be rapidly reflected by FL levels.FL can accurately and timely characterize intestinal inflammation in IBD. | Marrieth G Rubio Kofi Amo-Mensah James M Gray Vu Q Nguyen Sam Nakat Douglas Grider Kim Love James H Boone Dario Sorrentino | 2019 | World Journal of Gastrointestinal Pathophysiology2019，10，5： | 4 |
| 11 | 光导在折射率引导光纤、多孔光纤、光子带隙光纤和纳米线中的简要定性解释(英文)显示文摘本文是一篇教学论文,旨在通过对具体实例中不同物理过程的分析来定性解释光导拓宽固体材料折射率引导光纤光谱、多孔光纤光谱、光子带隙光纤光谱和纳米线光谱的原理。 | LOVE John | 2014 | 中国光学2014，7，3： | 4 |
| 12 | Comparison of Cold and Warm Ischemia During Partial Nephrectomy in 660 Solitary Kidneys Reveals Predominant Role of Nonmodifiable Factors in Determining Ultimate Renal Function显示文摘 | Brian R. Lane Paul Russo Robert G. Uzzo Adrian V. Hernandez Stephen A. Boorjian R. Houston Thompson Amr F. Fergany Thomas E. Love Steven C. Campbell | 2011 | The Journal of Urology2011，，2： | 3 |
| 13 | Trade credit and bank credit: Evidence from recent financial crises显示文摘 | Inessa Love Lorenzo A. Preve Virginia Sarria-Allende | 2006 | Journal of Financial Economics2006，，2： | 3 |
| 14 | Financial development and dynamic investment behavior: Evidence from panel VAR显示文摘 | Inessa Love Lea Zicchino | 2006 | Quarterly Review of Economics and Finance2006，，2： | 3 |
| 15 | Diamond like carbon coatings for potential application in biological implants—a review显示文摘 | C.A. Love R.B. Cook T.J. Harvey P.A. Dearnley R.J.K. Wood | 2012 | Tribology International2012，，： | 2 |
| 16 | Corporate governance, investor protection, and performance in emerging markets显示文摘 | Leora F. Klapper Inessa Love | 2003 | Journal of Corporate Finance2003，，5： | 2 |
| 17 | 不确定RIBA结果在HCV感染诊断中的预测意义显示文摘目的:评价诊断丙肝病毒(HCV)感染时不确定的重组免疫印迹试验(R IBA)结果的预测意义。方法:从1550份血清结果中筛选出142份不确定结果进行回顾性分析,分别分析4个条带出现单反应的几率及其预测意义。结果:142份不确定结果中单条带反应率分别为:c33c 51%,c-22(p)36%,N S5 11%,C 100(p)2%。各单反应条带中酶免法(E IA)结果呈高滴度同时多聚酶链反应(PCR)结果呈阳性的率分别为:c33c 60%,c-22(p)26%,N S5 8%,c100(p)0%。4个单反应条带中E IA与PCR同时呈阴性的率相同。结论:R IBA4个条带出现单条带反应的几率不同;4个条带中c33c的阳性预测值最高,为60%,提示c33c单阳性预示很可能感染HCV,其它三个条带的阳性预测值较低且无差异;4个条带的假阳性预测值低且无差异,提示单条带阳性者未感染HCV的可能性小。 | 张鸿 苏兴利 刘晓兰 张树林 Arthur Love | 2006 | 陕西医学杂志2006，35，11： | 2 |
| 18 | Learning by exporting: Lessons from high-technology SMEs显示文摘 | James H. Love Panagiotis Ganotakis | 2013 | International Business Review2013，，1： | 2 |
| 19 | Combined compression-torsion buckling test of laminated composite cylindrical shells显示文摘 | Wilking D J Love T S | 1974 | AIAA1974，12，3： | 2 |
| 20 | Are foreign investors attracted to weak environmental regulations? Evaluating the evidence from China显示文摘 | Judith M. Dean Mary E. Lovely Hua Wang | 2008 | Journal of Development Economics2008，，1： | 2 |
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