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| 1 | Percutaneous microwave ablation vs radiofrequency ablation in the treatment of hepatocellular carcinoma显示文摘Hepatocellular cancer ranks fifth among cancers and is related to chronic viral hepatitis, alcohol abuse,steatohepatitis and liver autoimmunity. Surgical resection and orthotopic liver transplantation have curative potential, but fewer than 20% of patients are suitable candidates. Interventional treatments are offered to the vast majority of patients. Radiofrequency(RFA) and microwave ablation(MWA) are among the therapeutic modalities, with similar indications which include the presence of up to three lesions, smaller than 3 cm in size, and the absence of extrahepatic disease. The therapeutic effect of both methods relies on thermal injury, but MWA uses an electromagnetic field as opposed to electrical current used in RFA. Unlike MWA, the effect of RFA is partially limited by the heat-sink effect and increased impedance of the ablated tissue. Compared with RFA, MWA attains a more predictable ablation zone, permits simultaneous treatment of multiple lesions, and achieves larger coagulation volumes in a shorter procedural time. Major complications of both methods are comparable and infrequent(approximately 2%-3%), and they include haemorrhage, infection/abscess, visceral organ injury, liver failure, and pneumothorax. RFA may incur the additional complication of skin burns. Nevertheless, there is no compelling evidence for differences in clinical outcomes, including local recurrence rates and survival. | Loukia S Poulou Evanthia Botsa Ioanna Thanou Panayiotis D Ziakas Loukas Thanos | 2015 | World Journal of Hepatology2015，7，8： | 37 |
| 2 | 环北太平洋地区现代植被中C3/C4植物相对丰度与气候条件关系研究显示文摘按照一个统一的方法,即以?24‰和?14‰作为纯C3和纯C4植被下表土总有机质碳同位素组成(δ13CTOC)的端元值,利用来自环北太平洋地区的中国东部、澳大利亚以及北美大平原地区的表土δ13CTOC数据,估算了这3个区域现代植被中C3和C4植物的相对生物量贡献比例,并和这3个区域相应的主要气候因素(年均温和年降水量)进行了对比,进而探讨了现代植被中C3/C4植物相对丰度与气候条件之间的关系.结果表明,温度条件对C4植物生物量贡献具有决定性影响;然而,即使温度条件满足C4植物生长的需要,随着温度的进一步上升,降水量应相应的下降,C4植物方能保持其优势地位.这一结果与对现代C4植物种属地理分布调查获得的结论基本是一致的.从而,这一结果为上述区域过去地质历史时期C3/C4植物相对丰度变化记录的古环境解译提供了重要的参考资料. | 饶志国 朱照宇 贾国东 陈发虎 BARTON Loukas 张家武 强明瑞 | 2010 | 科学通报2010，55，12： | 11 |
| 3 | Schistosoma mansoni proteins attenuate gastrointestinal motility disturbances during experimental colitis in mice显示文摘AIM:To investigate the therapeutic effect of Schistosoma mansoni(S.mansoni) soluble worm proteins on gastrointestinal motility disturbances during experimental colitis in mice. METHODS:Colitis was induced by intrarectal injection of trinitrobenzene sulphate(TNBS) and 6 h later,mice were treated ip with S.mansoni proteins.Experiments were performed 5 d after TNBS injection.Inflammationwas quantified using validated inflammation parameters. Gastric emptying and geometric center were measured to assess in vivo gastrointestinal motility.Peristaltic activity of distal colonic segments was studied in vitro using a modified Trendelenburg set-up.Cytokine profiles of T-lymphocytes isolated from the colon were determined by real time reverse transcriptase-polymerase chain reaction. RESULTS:Intracolonic injection of TNBS caused severe colitis.Treatment with S.mansoni proteins significantly ameliorated colonic inflammation after 5 d.TNBS did not affect gastric emptying but significantly decreased the geometric center and impaired colonic peristaltic activity 5 d after the induction of colitis.Treatment with S.mansoni proteins ameliorated these in vivo and in vitro motility disturbances.In addition,TNBS injection caused a downregulation of effector T cell cytokines after 5 d,whereas a S.mansoni protein effect was no longer observed at this time point. CONCLUSION:Treatment with S.mansoni proteins attenuated intestinal inflammation and ameliorated motility disturbances during murine experimental colitis. | Nathalie E Ruyssers Benedicte Y De Winter Joris G De Man Natacha D Ruyssers Ann J Van Gils Alex Loukas Mark S Pearson Joel V Weinstock Paul A Pelckmans Tom G Moreels | 2010 | World Journal of Gastroenterology2010，16，6： | 11 |
| 4 | Maximal function characterizations of Hardy spaces on RD-spaces and their applications显示文摘Let X be an RD-space, i.e., a space of homogeneous type in the sense of Coifman and Weiss, which has the reverse doubling property. Assume that X has a 'dimension' n. For α∈ (0, ∞) denote by Hαp(X ), Hdp(X ), and H?,p(X ) the corresponding Hardy spaces on X defined by the nontangential maximal function, the dyadic maximal function and the grand maximal function, respectively. Using a new inhomogeneous Calder′on reproducing formula, it is shown that all these Hardy spaces coincide with Lp(X ) when p ∈ (1, ∞] and with each other when p ∈ (n/(n + 1), 1]. An atomic characterization for H*,p(X ) with p ∈ (n/(n + 1), 1] is also established; moreover, in the range p ∈ (n/(n + 1), 1], it is proved that the space H?,p(X ), the Hardy space Hp(X ) defined via the Littlewood-Paley function, and the atomic Hardy space of Coifman and Weiss coincide. Furthermore, it is proved that a sublinear operator T uniquely extends to a bounded sublinear operator from Hp(X ) to some quasi-Banach space B if and only if T maps all (p, q)-atoms when q ∈ (p, ∞)∩[1, ∞) or continuous (p, ∞)-atoms into uniformly bounded elements of B. | Loukas GRAFAKOS | 2008 | Science China Mathematics2008，51，12： | 10 |
| 5 | Apparent diffusion coefficient values of normal testis and variations with age显示文摘在阴囊的病理的评估的散开加权的磁性的回声成像(DWI ) 的实用性最近被报导了。当解释正常阴囊的解剖和病理时,阴囊的明显的散开系数(模数转换器) 珍视的正常和他们有年龄的变化的一本标准参考书是必要的。我们用 DWI 评估了 147 个正常睾丸,包括从 20-39 年(组 1 ) 的 53 个人的 71 个睾丸,从 40-69 年(组 2 ) 的 42 个人的 67 个睾丸和从比 70 年(组 3 ) 老的六个人的九个睾丸。DWI 沿着轴的飞机被执行,用单个射击, multislice 纺纱回响平面散开脉搏顺序和 0 和 900 s 公里 −2 的 b 值。正常阴囊的实质的模数转换器价值的平均数和标准差独立为每个年龄组被计算。柱子 hoc 分析(Dunnett T3 ) 跟随的变化(ANOVA ) 的分析被用于统计目的。模数转换器价值(×正常阴囊的织物的 10 −3 公里 2 s −1) 在年龄组之中是不同的(组 1:1.08 ±0.13;组 2:1.15 ±0.15 和组 3:1.31 ±0.22 ) 。ANOVA 在年龄组之中在吝啬的模数转换器揭示了差别(F = 11.391, P <0.001 ) 。波斯特 hoc 分析显示出组之间的差别 1 和 2 (P = 0.008 ) 并且在组之间 1 和 3 (P = 0.043 ) ,然而并非在组之间 2 和 3 (P = 0.197 ) 。我们的调查结果建议正常阴囊的织物的模数转换器价值与推进年龄增加。 | Athina C Tsili Dimitrios Giannakis Anastasios Sylakos Alexandra Ntorkou Loukas G Astrakas Nikolaos Sofikitis Maria I Argyropoulou | 2014 | Asian Journal of Andrology2014，16，3： | 8 |
| 6 | Boundedness of paraproduct operators on RD-spaces显示文摘Let(X,d,μ) be an RD-space with 'dimension' n,namely,a space of homogeneous type in the sense of Coifman and Weiss satisfying a certain reverse doubling condition.Using the Calder'on reproducing formula,the authors hereby establish boundedness for paraproduct operators from the product of Hardy spaces H p(X) × H q(X) to the Hardy space H r(X),where p,q,r ∈(n/(n + 1),∞) satisfy 1/p + 1/q = 1/r.Certain endpoint estimates are also obtained.In view of the lack of the Fourier transform in this setting,the proofs are based on the derivation of appropriate kernel estimates. | GRAFAKOS Loukas | 2010 | Science China Mathematics2010，53，8： | 7 |
| 7 | Relationship between climatic conditions and the relative abundance of modern C_3 and C_4 plants in three regions around the North Pacific显示文摘Using -24‰ and -14‰ as the endpoints of stable carbon isotopic composition of total organic carbon (δ 13CTOC) of surface soil under pure C3 and C4 vegetation, and surface soil δ 13CTOC data from eastern China, Australia and the Great Plains of North America, we estimate the relative abundance of C3/C4 plants (i.e., the ratio of C3 or C4 biomass to local primary production) in modern vegetation for each region. The relative abundance of modern C3/C4 vegetation from each region is compared to the corresponding climatic parameters (mean annual temperature and precipitation) to explore the relationship between relative C4 abundance and climate. The results indicate that temperature controls the growth of C4 plants. However, even where temperature is high enough for the growth of C4 plants, they will only dominate the landscape when precipitation declines as temperatures increase. Our results are consistent with those of other investigations of the geographic distribution of modern C4 plant species. Therefore, our results provide an important reference for interpretation of past C3/C4 relative abundance records in these three regions. | RAO ZhiGuo ZHU ZhaoYu JIA GuoDong CHEN FaHu BARTON Loukas ZHANG JiaWu QIANG MingRui | 2010 | Chinese Science Bulletin2010，55，18： | 7 |
| 8 | Thermal Ablation in the Management of Adrenal Metastasis Originating from Non-small Cell Lung Cancer: A 5-year Single-center Experience显示文摘 | Evanthia I Botsa Ioanna L Thanou Aspasia T Papatheodoropoulou Loukas I Thanos | 2017 | Chinese Medical Journal2017，，17： | 6 |
| 9 | Restless legs syndrome is contributing to fatigue and low quality of life levels in hemodialysis patients显示文摘AIM To examine whether hemodialysis(HD) patients with restless legs syndrome(RLS) are subjects of greater fatigue and impaired quality of life(QoL) compared to HD patients without RLS.METHODS Eighty five stable HD patients participated in this study. According to their RLS status, the patients were dividedinto the RLS group(n = 23) and the non-RLS group(n = 62). QoL, fatigue, sleep quality, daily sleepiness and depression symptoms were assessed by using various questionnaires. Finally, biochemical parameters including iron, ferritin, hemoglobin, hematocrit and parathormone were assessed. RESULTS The HD patients with RLS scored worse in all the questionnaires used in the study(P < 0.05). The patients with RLS were more likely to receive the HD therapy on the morning shift, whilst 43.5% of the RLS patients reported to experience the RLS symptoms also during HD. The severity of RLS was correlated with fatigue, depression score and sleep quality(P < 0.05). CONCLUSION HD patients with RLS are subject to lower QoL related parameters and greater fatigue compared to HD patients without RLS. RLS should be successfully managed in order to improve the QoL of the sufferers. | Christoforos D Giannaki Michael Hadjigavriel Akis Lazarou Aristos Michael Loukas Damianou Efthimios Atmatzidis Ioannis Stefanidis Georgios M Hadjigeorgiou Giorgos K Sakkas Marios Pantzaris | 2017 | World Journal of Nephrology2017，6，5： | 3 |
| 10 | Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm显示文摘 | Jeffrey Bethony Simon Brooker Marco Albonico Stefan M Geiger Alex Loukas David Diemert Peter J Hotez | 2006 | The Lancet2006，，9521： | 2 |
| 11 | Opisthorchiasis and Opisthorchis -associated cholangiocarcinoma in Thailand and Laos显示文摘 | Banchob Sripa Jeffrey M. Bethony Paiboon Sithithaworn Sasithorn Kaewkes Eimorn Mairiang Alex Loukas Jason Mulvenna Thewarach Laha Peter J. Hotez Paul J. Brindley | 2010 | Acta Tropica2010，，： | 2 |
| 12 | DNA technological progress toward advanced diagnostic tools to support human hookworm control显示文摘 | R.B. Gasser C. Cantacessi A. Loukas | 2007 | Biotechnology Advances2007，，1： | 2 |
| 13 | Surface landmarks for the junction between the transverse and sigmoid sinuses : appli-cation of the 'strategic' burr hole for suboccipital craniotomy显示文摘 | TUBBS R S LOUKAS M SHOJA M M | 2009 | Neurosurgery2009，65，6： | 1 |
| 14 | Quantitative structure-binding relationships(QSBR) and artificial networks: improved predictions in drug: cyclodextrin inclusion complexes显示文摘 | Loukas Y L | 2001 | Int J Pharm2001，226，： | 1 |
| 15 | An unusual union of the inter- costobrachial nerve and the medial pectoral nerve 显示文摘 | Loukas M Grabska J Tubbs RS | 2007 | Folia Morphol (Warsz)2007，66，4： | 1 |
| 16 | The tumorigenic liver fluke Opisthorchis viverrini – multiple pathways to cancer显示文摘 | Banchob Sripa Paul J. Brindley Jason Mulvenna Thewarach Laha Michael J. Smout Eimorn Mairiang Jeffrey M. Bethony Alex Loukas | 2012 | Trends in Parasitology2012，，10： | 1 |
| 17 | An unusual innervationof pectorlis and major muscles from a branch of the intercosbrachialnerve显示文摘 | Loukas M Louis RG Jr Fogg QA | 2006 | Clin Anat2006，19，04： | 1 |
| 18 | Spatial variability of ref- erence evapotranspiration in Greece显示文摘 | Dalezios N R Loukas A Bampzelis D | 2002 | Physics and Chemistry of the Earth2002，27，： | 1 |
| 19 | Opioid activities and structures of α- casein-derived exorphins 显示文摘 | Loukas S Varoucha D Zioudrou C | 1983 | Biochemistry1983，22，19： | 1 |
| 20 | Phrenic nerve neurotization utilizing the spinal accessory nerve:technical note with potential application in patients with high cervical quadriplegia显示文摘 | Tubbs RS Pearson B Loukas M | 2008 | Childs Nerv Syst2008，24，11： | 1 |
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