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| 1 | 抗氧化剂一、二级预防随机试验中的死亡率系统回顾及汇总分析显示文摘背景:抗氧化剂正用于多种疾病的预防。
目的:评估补充抗氧化剂对一、二级预防随机临床试验参试者死亡率的影响。数据来源及试验选择:检索2005年10月前的电子数据库以及发表的文献目录。所有于成人中进行的、比较单独或联合使用β胡萝卜素、维生素A、维生素C(抗坏血酸)、维生素E及硒剂的安慰剂或空白治疗对照随机试验均纳入分析。使用随机、盲法及随访作为评估入选试验偏倚的指标。采用随机效应分析法分析抗氧化剂对全因死亡率的影响,结果以相对危险度(relative risk,RR)及其95%可信区间(confidence interval,CI)表示。采用汇总回归评估试验协变量的影响。
数据提取:共入选68项随即试验,包括232606例参试者(385篇文章)。
数据整合:将所有低和高偏倚风险抗氧化剂试验汇总后发现,抗氧化剂对死亡率无显著影响(RR,1.02;95%CI,0.98~1.06)。多变量汇总回归分析表明,低偏倚风险试验(RR,1.16;95%CI,1.05~1.29)和硒剂(RR,0.998;95%CI,0.997~0.9995)与死亡率显著相关。在包括180938例参试者在内的47项低偏倚试验中,补充抗氧化剂显著增加死亡率(RR,1.05;95%CI,1.02~1.08)。排除硒剂试验后,在低偏倚风险试验中,β胡萝卜素(RR,1.07;95%CI,1.02~1,11)、维生素A(RR,1.16;95%CI,1.10~1.24)以及维生素E(RR,1.04;95%CI,1.01~1.07)单独或联合使用均显著增加死亡率。维生素C及硒剂对死亡率无显著影响。
结论:β胡萝卜素、维生素A及维生素E治疗可能增加死亡率。维生素C和硒剂对死亡率的影响需要进一步研究。 | Goran Bjelakovic Dimitrinka Nikolova Lise Lotte Gluud Rose G. Simonetti Christian Gluud 顾佳(译) | 2007 | 美国医学会杂志(中文版)2007，26，5： | 35 |
| 2 | Development and predictive validity of the cirrhosis-associated ascites symptom scale: A cohort study of 103 patients显示文摘AIM To develop a scale of domains associated with the health-related quality-of-life(HRQOL) in patients with cirrhosis-related ascites.METHODS We initially undertook literature searches and a qualitative study in order to design a cirrhosis-associated ascites symptom(CAS) scale describing symptoms with a potential detrimental impact on health related quality of life(HRQL)(the higher the score, the worse the symptoms). Discriminatory validity was assessed in a validation cohort including cirrhotic patients with(1) tense/severe;(2) moderate/mild; or(3) no ascites(controls). Patients also completed chronic liver disease questionnaire(CLDQ) and the Euro QoL 5-Dimensions 5-Level(EQ-5D-5L) questionnaire evaluating HRQL. The relation between scale scores was analysed using Spearman correlations. RESULTS The final CAS scale included 14 items. The equivalent reliability was high(Chronbach's alpha 0.88). The validation cohort included 103 patients(72% men, mean age 62.4 years). The mean scores for each question in the CAS scale were higher for patients with severe/tense ascites than for mild/moderate ascites and controls. Compared with controls(mean = 9.9 points), the total CAS scale score was higher for severe/tense ascites(mean = 23.8 points) as well as moderate/mild ascites(mean = 18.6 points)(P < 0.001 both groups). We found a strong correlation between the total CAS and CLDQ score(rho = 0.82, P < 0.001) and a moderate correlation between the CAS and the EQ-5D-5L score(0.67, P < 0.001). CONCLUSION The CAS is a valid tool, which reflects HRQOL in patients with ascites. | Agnete Nordheim Riedel Nina Kimer Anne-Sofie Houlberg Jensen Emilie Kristine Dahl Mads Israelsen Luise Aamann Lise Lotte Gluud | 2018 | World Journal of Gastroenterology2018，24，15： | 3 |
| 3 | LED照明补光技术在花卉生产中的尝试显示文摘Knud Jepsen育种公司是丹麦长寿花“女王”系列的世界知名育种商和生产商,位于丹麦希那卡普。公司设施生产面积达12万平方米,高度自动化和良好的运行效率是公司成功的重要保证。经过不断探索,三年前公司与飞利浦电器合作,就LED照明补光技术运用于公司“女王”系列长寿花生产的潜在可能性进行合作。 | Lotte Bjarke 丁怀敏 | 2011 | 中国花卉园艺2011，，18： | 3 |
| 4 | Hyponatremia, Hypernatremia, and Mortality in Patients With Chronic Kidney Disease With and Without Congestive Heart Failure显示文摘 | Csaba P. Kovesdy Evan H. Lott Jun Ling Lu Sandra M. Malakauskas Jennie Z. Ma Miklos Z. Molnar Kamyar Kalantar-Zadeh | 2012 | Circulation2012，，5： | 2 |
| 5 | Severe Hand, Foot, and Mouth Disease Associated with Coxsackievirus A6 - Alabama, Connecticut, California, and Nevada, November 201 1 - February 2012显示文摘 | McIntyre Mary G Stevens Kelly M Davidson Sherri Pippin Tina Magill Dagny Kulhanjian Julie A Kelly Daniel Greenhow Tara L Salas Maria L Yagi Shigeo Padilla Tasha Berumen Ricardo Glaser Carol Landry Marie Louise Lott Jason Chen Lei Paulson | 2012 | EN2012，，12： | 2 |
| 6 | 煤焦油的加氢反应性显示文摘本研究采用电磁拖动搅拌高压反应釜对两种煤焦油进行了催化加氢反应。反应结果表明、两种煤焦油在氢压17MPa;反应温度450℃;反应时间90min的反应条件下,都具有一定的加氢反应活性。中低温煤焦油的加氢反应活性明显高于高温煤焦油,催化加氢反应使中低温煤焦油中200℃前的馏分量由6.44%增加到41.57%,增加了约6.5倍。加氢反应使煤焦油得到了较高的提质。 | 凌开成 Roger Lott Edward G. Fitzpatrick | 1993 | 太原工业大学学报1993，24，2： | 2 |
| 7 | 洗衣房中的创新:在商用洗衣房中使用酶制剂技术来节约成本并提升可持续发展指数显示文摘酶制剂能为化学品供应商以及酒店洗衣房节约成本。爱尔兰最新案例为中国的化学品和商用洗衣业带来灵感。爱尔兰化学品供应商、酒店洗衣厂发现了一系列节约成本的方法伴随着能源价格上升、布草报废的成本上升以及来自酒店和医院客户对可持续发展的诉求增长,商用洗衣房找寻不同的方式来削减成本、创新程序以及控制他们的服务对环境的影响。 | Lotte Jensen-Holm 陈娟 | 2015 | 中国洗涤用品工业2015，，9： | 2 |
| 8 | CDX2 is a useful marker of intestinal-type differentiation : a tissue microarray-based study of 629 tumors from various sites 显示文摘 | De Lott LB Morrison C Suster S | 2005 | Arch Pathol Lab MED2005，129，9： | 1 |
| 9 | Clonal analysis of the differentiation potential of human adipose-derived adult stem cells 显示文摘 | Guilak F Lott KE Awad HA | 2006 | J Cell Physiol2006，206，1： | 1 |
| 10 | Studying the use of fuzzy inference systems for motor imagery classification显示文摘 | Lotte F Lécuyer A Lamarche F | 2007 | IEEE Transactions on Neural System and Rehabilitation Engineering2007，15，2： | 1 |
| 11 | Pd(O)-catalyzed allylie alkylation in the synthesis of (±)carbovir 显示文摘 | LISE LOTTE G TORE B | 1992 | Tetrahedron Letters1992，33，8： | 1 |
| 12 | Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy显示文摘 | Wallace DC Singh G Lott MT Hodge JA Schurr TG Lezza AMS | 1988 | Science1988，242，： | 1 |
| 13 | Gravity waves generated by shearedthree-dimensional potential vorticity anomalies 显示文摘 | Lott F Plougonven R | 2012 | J AtmosSci2012，69，： | 1 |
| 14 | Pathophysiology and diagnostic value of urinary trypsin inhibitors显示文摘 | Pugia M J Lott JA | 2005 | C lin Chem Lab Med2005，43，1： | 1 |
| 15 | The effects of high-air velocity on broiler performance 显示文摘 | SIMMONS J D LOTT B D MILES D M | 2003 | Poultry Science2003，82，2： | 1 |
| 16 | MITOMAP: a human mitochondrial genome database-1998 update 显示文摘 | Lott M T Brown M D | 1998 | Nucle Acids Res1998，26，1： | 1 |
| 17 | Phytic acid and phosphorus in crop seeds and fruits:a global estimate显示文摘 | LOTT J N OCKENDEN I RABOY V | 2000 | Seed Science Research2000，10，1： | 1 |
| 18 | Growth responses of male broilers subjected to in- creasing air velocities at high ambient temperatures and a high dew point 显示文摘 | DOZIER W R 3rd LOTT B D BRANTON S L | 2005 | Poultry Science2005，84，6： | 1 |
| 19 | A review of classification algorithms for EEG-based brain-computer interfaces显示文摘 | LOTTE F CONGEDO M LECUYER A | 2007 | Journal of Neural Engineering2007，4，2： | 1 |
| 20 | Use of medians and 'average of normals' of patient's data for assessment of long-term analytical stability显示文摘 | Lott JA Smith DA Mitchell LC | 1996 | Clin Chem1996，42，16： | 1 |
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