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| 1 | Probing the limits of plasmonic enhancement using a two-dimensional atomic crystal probe显示文摘Achieving larger electromagnetic enhancement using a nanogap between neighboring metallic nanostructures has been long pursued for boosting light–matter interactions.However,the quantitative probing of this enhancement is hindered by the lack of a reliable experimental method for measuring the local fields within a subnanometer gap.Here,we use layered MoS2 as a two-dimensional atomic crystal probe in nanoparticle-on-mirror nanoantennas to measure the plasmonic enhancement in the gap by quantitative surface-enhanced Raman scattering.Our designs ensure that the probe filled in the gap has a well-defined lattice orientation and thickness,enabling independent extraction of the anisotropic field enhancements.We find that the field enhancement can be safely described by pure classical electromagnetic theory when the gap distance is no<1.24 nm.For a 0.62 nm gap,the probable emergence of quantum mechanical effects renders an average electric field enhancement of 114-fold,38.4%lower than classical predictions. | Wen Chen Shunping Zhang Meng Kang Weikang Liu Zhenwei Ou Yang Li Yexin Zhang Zhiqiang Guan Hongxing Xu | 2018 | Light(Science & Applications)2018，7，1： | 4 |
| 2 | Geospatial technologies for Chang’e-3 and Chang’e-4 lunar rover missions显示文摘This paper presents a brief overview of the geospatial technologies developed and applied in Chang’e-3 and Chang’e-4 lunar rover missions.Photogrammetric mapping techniques were used to produce topographic products of the landing site with meter level resolution using orbital images before landing,and to produce centimeter-resolution topographic products in near real-time after landing.Visual positioning techniques were used to determine the locations of the two landers using descent images and orbital basemaps immediately after landing.During surface operations,visual-positioning-based rover localization was performed routinely at each waypoint using Navcam images.The topographic analysis and rover localization results directly supported waypoint-to-waypoint path planning,science target selection and scientific investigations.A GIS-based digital cartography system was also developed to support rover teleoperation. | Kaichang Di Zhaoqin Liu Wenhui Wan Man Peng Bin Liu Yexin Wang Sheng Gou Zongyu Yue | 2020 | Geo-Spatial Information Science2020，23，1： | 3 |
| 3 | Dual-channel type tunable field-effect transistors based on vertical bilayer WS2(1−x)Se2x/SnS2 heterostructures显示文摘Layered semiconductor heterostructures are essential elements in modern electronic and optoelectronic devices.Dynamically engineering the composition of these heterostructures may enable the flexible design of the properties of heterostructure-based electronics and optoelectronics as well as their optimization.Here,we report for the first time a two-step chemical vapor deposition approach for a series of WS2(1−x)Se2x/SnS2 vertical heterostructures with high-quality and large areas.The steady-state photoluminescence results exhibit an obvious composition-related quenching ratio,revealing a strong coherence between the band offset and the charge transfer efficiency at the junction interface.Based on the achieved heterostructures,dual-channel backgate field-effect transistors were successfully designed and exhibited typical composition-dependent transport behaviors,and pure n-type unipolar transistors to ambipolar transistors were realized in such systems.The direct vapor growth of these novel vertical WS2(1−x)Se2x/SnS2 heterostructures could offer an interesting system for probing new physical properties and provide a series of layered heterostructures for high-quality devices. | Biyuan Zheng Dong Li Chenguang Zhu Jianyue Lan Xingxia Sun Weihao Zheng Huawei Liu Xuehong Zhang Xiaoli Zhu Yexin Feng Tao Xu Litao Sun Gengzhao Xu Xiao Wang Chao Ma Anlian Pan | 2020 | InfoMat2020，2，4： | 3 |
| 4 | Landing site topographic mapping and rover localization for Chang’e-4 mission显示文摘This paper presents the techniques and results of landing-site topographic mapping and rover localization using orbital,descent and rover images in the Chang’e-4 mission.High-resolution maps of the landing site are generated from orbital and descent images.Local digital elevation models and digital orthophoto maps with 0.02 m resolution are generated at each waypoint.The location of the lander is determined as(177.588?E,45.457?S)using festure-matching techniques.The cross-site visual localization method is routinely used to localize the rover at each waypoint to reduce error accumulation from wheel slippage and IMU drift in dead reckoning.After the first five lunar days,the rover travels 186.66 m from the lander,according to the cross-site visual localization.The developed methods and results have been directly utilized to support the mission’s operations.The maps and localization information are also valuable for supporting multiple scientific explorations of the landing site. | Zhaoqin LIU Kaichang DI Jian LI Jianfeng XIE Xiaofeng CUI Luhua XI Wenhui WAN Man PENG Bin LIU Yexin WANG Sheng GOU Zongyu YUE Tianyi YU Lichun LI Jia WANG Chuankai LIU Xin XIN Mengna JIA Zheng BO Jia LIU Runzhi WANG Shengli NIU Kuan ZHANG Yi YOU Bing LIU Jiangang LIU | 2020 | Science China(Information Sciences)2020，63，4： | 3 |
| 5 | Sirolimus combined with oseltamivir and corticosteroid treatment for a puerpera with severe pneumonia caused by 2009 pandemic H1N1:A case report显示文摘Severe pneumonia in patients infected with the 2009 pandemic H1N1(pH1N1)virus was partially attributed to excessive immune response.Anti-virus treatment for these patients was insufficient.Here we reported the therapy effect of sirolimus,an immunosuppressor,combined with oseltamivir and corticosteroid for a puerpera with severe pneumonia caused by pH1N1 virus.This patient has infected with the pH1N1 virus in late pregnancy,and antiviral therapy was not implemented timely.She developed severe pneumonia and ARDS rapidly and need receive a cesarean section on the 39th week after pregnancy.After giving birth to a healthy baby,she received a combination of oseltamivir,sirolimus and corticosteroid,and improved in the following days.Moreover,the cytokines in serum and viral loads in BALF decreased significantly.She recovered without infectious symptoms and was discharged.Sirolimus combined with oseltamivir and corticosteroid is likely responsible for lowering the viral loads,reducing the patient's cytokine level,and further improving her clinical outcomes.It provides evidence that adjuvant treatment was beneficial to patients with severe pneumonia induced by the pH1N1 virus. | Lijun Suo Xiaofeng Yu Yongfeng Hu Hongyun Cao Xiaohui Zou Peiquan Wang Tao Xu Xiangzhi Zhou Yexin Wu Lili Ren Bo Liu Bin Cao | 2021 | Biosafety and Health2021，3，6： | 2 |
| 6 | Dietary Litsea cubeba essential oil supplementation improves growth performance and intestinal health of weaned piglets显示文摘This paper was to determine the effects of dietary Litsea cubeba essential oil(LEO)supplementation on growth performance,immune function,antioxidant level,intestinal morphology and microbial composition in weaned piglets.One hundred and ninety-two piglets(Duroc×[Large White×Landrace])with 6.85±0.22 kg mean body weight weaned at 21 d of age were randomly assigned to 4 treatment groups with 8 replicates and were fed with a basal diet(CON)or CON diet containing 100(LLEO),200(MLEO)and 400(HLEO)mg/kg LEO.The results revealed that HLEO supplementation(P<0.05)increased the average daily gain on d 28 compared with CON.MLEO and HLEO supplementation decreased(P<0.05)feed conversion ratio.LEO-containing diets had a lower(P<0.05)diarrhea rate.Supple-mentation with HLEO increased(P<0.05)total antioxidant capacity(T-AOC)both in the serum and liver.Meanwhile,the supplementation of MLEO and HLEO resulted in higher(P<0.05)glutathione peroxidase(GPx)activities both in serum and liver.Supplementation of HLEO increased(P<0.05)serum immu-noglobulin A,immunoglobulin G and interleukin-10,whereas supplementation with MLEO and HLEO decreased(P<0.05)tumor necrosis factor-α.Villus height in the duodenum or jejunum was increased(P<0.05)in the HLEO group,and the villus height to crypt depth ratio in the jejunum was also improved(P<0.05)in the MLEO group.The addition of LEO increased(P<0.05)the richness and diversity of the microbial community in the cecum,which mainly increased the relative abundance of Oscillospir-aceae_UCG-005,Faecalibacterium,Blautia and Coprococcus.Piglets supplemented with HLEO increased(P<0.05)the concentration of short chain fatty acids(SCFA),including acetic acid in the cecum and propionic acid in the colon.In conclusion,these findings indicated that LEO supplementation improved growth performance and intestinal health in weaned piglets. | Zhe Yang Fang Wang Yexin Yin Peng Huang Qian Jiang Zhimou Liu Yulong Yin Jiashun Chen | 2023 | Animal Nutrition2023，，2： | 1 |
| 7 | Sub-Regional Infrared-Visible Image Fusion Using Multi-Scale Transformation显示文摘Infrared-visible image fusion plays an important role in multi-source data fusion,which has the advantage of integrating useful information from multi-source sensors.However,there are still challenges in target enhancement and visual improvement.To deal with these problems,a sub-regional infrared-visible image fusion method(SRF)is proposed.First,morphology and threshold segmentation is applied to extract targets interested in infrared images.Second,the infrared back-ground is reconstructed based on extracted targets and the visible image.Finally,target and back-ground regions are fused using a multi-scale transform.Experimental results are obtained using public data for comparison and evaluation,which demonstrate that the proposed SRF has poten-tial benefits over other methods. | Yexin Liu Ben Xu Mengmeng Zhang Wei Li Ran Tao | 2022 | Journal of Beijing Institute of Technology2022，31，6： | 1 |
| 8 | Evolution of technology management system based on self-organization theory显示文摘Industrial and academic interest in how to effectively manage technology resources is increasing as it becomes more and more important.Effective managing of technology resources depends on technology management system,and thus understanding how such system evolves becomes an ongoing research topic.Based on the self-organization theory,this paper constructs an evolution model of technology management system.The simulation results show that the evolution of each of the technology management subsystem is affected by the knowledge growth rate of its own,and it is also affected by the coupling and synergy relationship with other subsystems.Moreover,the coupling and synergy relationship can make the speed of evolution higher than the knowledge growth rate of the subsystem itself. | WU Weiwei MA Qian LIU Yexin YANG Ying YUE Suzhen | 2021 | Journal of Systems Engineering and Electronics2021，32，6： | 1 |
| 9 | Impact of the synergy between technology management and technological capability on new product development:a system dynamics approach显示文摘This paper employs system dynamics to explore how the synergy between technology management and technological capability affects new product development.The results show that the synergy between technology management and technological capability has positive impact on new product development.Moreover, the leading synergy processes between technology management and technological capability in different new product development stages are different.This paper deepens the theoretical understanding of how to achieve new product development, and also provides useful guidance for firms to implement new product development. | MA Qian WU Weiwei LIU Yexin LIANG Zhou KOU Lingzhi | 2022 | Journal of Systems Engineering and Electronics2022，33，1： | 1 |
| 10 | Design and aligner-assisted fast fabrication of a microfluidic platform for quasi-3D cell studies on an elastic polymer显示文摘While most studies of mechanical stimulation of cells are focused on two-dimensional(2D)and three-dimensional(3D)systems,it is rare to study the effects of cyclic stretching on cells under a quasi-3D microenvironment as a linkage between 2D and 3D.Herein,we report a new method to prepare an elastic membrane with topographic microstructures and integrate the membrane into a microfluidic chip.The fabrication difficulty lay not only in the preparation of microstructures but also in the alignment and bonding of the patterned membrane to other layers.To resolve the problem,we designed and assembled a fast aligner that is cost-effective and convenient to operate.To enable quasi-3D microenvironment of cells,we fabricated polydimethylsiloxane(PDMS)microwell arrays(formed by micropillars of a few microns in diameter)with the microwell diameters close to the cell sizes.An appropriate plasma treatment was found to afford a coating-free approach to enable cell adhesion on PDMS.We examined three types of cells in 2D,quasi-3D,and 3D microenvironments;the cell adhesion results showed that quasi-3D cells behaved between 2D and 3D cells.We also constructed transgenic human mesenchymal stem cells(hMSCs);under cyclic stretching,the visualizable live hMSCs in microwells were found to orientate differently from in a 3D Matrigel matrix and migrate differently from on a 2D flat plate.This study not only provides valuable tools for microfabrication of a microfluidic device for cell studies,but also inspires further studies of the topological effects of biomaterials on cells. | Yingning He Yue Yu Yuqian Yang Yexin Gu Tianjiao Mao Yang Shen Qiong Liu Ruili Liu Jiandong Ding | 2022 | Bioactive Materials2022，7，9： | 0 |
| 11 | A model for knowledge transfer in a multi-agent organization based on lattice kinetic model显示文摘A study on knowledge transfer in a mutli-agent organization is performed by applying the basic principle in physics such as the kinetic theory.Based on the theoretical analysis of the knowledge accumulation process and knowledge transfer attributes,a special type of knowledge field(KF)is introduced and the knowledge diffusion equation(KDE)is developed.The evolution of knowledge potential is modeled by lattice kinetic equation and verified by numerical experiments.The new equation-based modeling developed in this paper is meaningful to simulate and predict the knowledge transfer process in firms.The development of the lattice kinetic model(LKM)for knowledge transfer can contribute to the knowledge management theory,and the managers can also simulate the knowledge accumulation process by using the LKM. | WU Weiwei MA Qian LIU Yexin KIM Yongjun | 2020 | Journal of Systems Engineering and Electronics2020，31，1： | 0 |
| 12 | Preparation and Modification of Micro-Mesoporous Carbon Materials for Toluene Adsorption显示文摘In the process of toluene adsorption, the choice of adsorbent is the key. In this work, micro-mesoporous carbon materials were prepared and characterized. The synthesis process was performed by using MCM-41 as the template, and sucrose and furfuryl alcohol as the carbon source, respectively. The toluene adsorption capacity of studied adsorbents was evaluated under different toluene initial concentration, temperature and bed height. In order to further improve the adsorption capacity, nitric acid was used for modification of the selected adsorbent. The adsorption performance after modification was also investigated. The prepared carbon materials were characteristic of typical type IV isotherms and pore size distribution was focused on micropores and mesopores. Compared with MCM-41, the prepared carbon materials showed high toluene adsorption capacity. After modification the specific surface area and oxygen groups of adsorbent were increased, making the adsorption capacity increase from 185.3 mg/g to a maximum value of 514.7 mg/g. The adsorption capacity of adsorbent mainly depended on its surface area and surface chemical property. | Liu Fang Xue Ming Wang Hongxi Chai Qingwen Li Meng Dai Yexin Zhao Chaocheng Wang Yongqiang | 2018 | China Petroleum Processing & Petrochemical Technology2018，20，1： | 0 |
| 13 | Photoluminescence and Raman Spectroscopy Study on Color Centers of Helium Ion-Implanted 4H-SiC显示文摘Color centers in silicon carbide(SiC)are promising candidates for quantum technologies.However,the richness of the polytype and defect configuration of SiC makes the accurate control of the types and position of defects in SiC still challenging.In this study,helium ion-implanted 4H-SiC was characterized by atomic force microscopy(AFM),confocal photoluminescence(PL),and confocal Raman spectroscopy at room temperature.PL signals of silicon vacancy were found and analyzed using 638-nm and 785-nm laser excitation by means of depth profiling and SWIFT mapping.Lattice defects(C-C bond)were detected by continuous laser excitation at 532 nm and 638 nm,respectively.PL/Raman depth profiling was helpful in revealing the three-dimensional distribution of produced defects.Differences in the depth profiling results and SRIM simulation results were explained by considering the depth resolution of the confocal measurement setup,helium bubbles,as well as swelling. | Ying Song Zongwei Xu Rongrong Li Hong Wang Yexin Fan Mathias Rommel Jiayu Liu Georgy V.Astakhov Gregor Hlawacek Bingsheng Li Jun Xu Fengzhou Fang | 2020 | Nanomanufacturing and Metrology2020，3，3： | 0 |
| 14 | Do alternative stable states exist in large shallow Taihu Lake,China?显示文摘Regime shifts from submersed macrophyte dominance to phytoplankton dominance have been widely reported in small-to medium-sized shallow lakes.However,alternative stable states in large shallow lakes(surface area>500 km^(2))remain unconfirmed.To understand the alternative stable states and the main influencing factors of submersed macrophytes in large lakes,the ecosystem states from monitoring data from 1959 to 2019 in large shallow Taihu Lake(2338 km^(2)in average depth of 2.12 m)in China were examined.Changes in submersed macrophyte coverage(C_(Mac))and phytoplankton chlorophyll a(Chl a)in the time series and their relationships with environmental factors were analyzed.During the field investigation from August 2018 to May 2019,nutrients and Chl a showed obvious heterogeneity across the lake,being generally higher in the western and northern areas and lower in the southeast area,while C_(Mac)was only observed in the eastern areas,e.g.,East Taihu Lake,Xukou Bay,and Gonghu Bay.During the long-term monitoring from 1959 to 2019 in the Central Region,Meiliang Bay,and East Taihu Lake,Chl a increased significantly in the time series.C_(Mac)varied slightly among different subareas,always at low levels(<10%)in the Central Region and Meiliang Bay but at relatively high levels in East Taihu Lake(10%–90%).Frequency distributions of response variables had no multimodality except for C_(Mac)in East Taihu Lake,with two peaks between 15%and 20%and between 55%and 60%.A dual relationship was found between Chl a and total phosphorus(TP)in the areas with and without macrophytes,while C_(Mac)showed no relationship with TP,and submersed macrophytes did not flourish in the Central Region and Meiliang Bay even when TP was at very low levels(≈10 mg/m3).Taihu Lake had similar algal turbidity(TurbAlg)as small-to mediumsized lakes but generally presented with higher values of nonalgal turbidity(TurbNonAlg),as did their contribution to total turbidity as a percentage.This study suggested that large shallow Taihu Lake may have no alternative stable states,but more evidence is needed for East Taihu Lake,which was dominated by macrophytes,as it remains unknown whether hysteresis occurs between the processes of eutrophication and oligotrophication.Unfavorable conditions caused by wind might be the main reason due to the absence of submersed macrophytes in Taihu Lake.These results demonstrate that stricter nutrient control is needed to maintain a healthy state or to recover from a decayed state for large lakes. | Yan LI Yu MA Haijun WANG Hongzhu WANG Yongde CUI Shijun BIAN Miao ZHANG Mengmei LIU Yexin YU Marc SCHALLENBERG | 2023 | Journal of Oceanology and Limnology2023，41，3： | 0 |
| 15 | Self-gating enhanced carrier transfer in semiconductor electrocatalyst verified in microdevice显示文摘Semiconductor electrocatalysis with weak conductivity can accumulate extremely high carriers at semiconductor-electrolyte interface by self-gating effect,which strongly promotes electrocatalytic efficiency.The correlation between semiconductor carrier mobility and electrocatalysis performance is still unclear.Herein atomic-thin transition metal dichalcogenides based composites have been developed for hydrogen evolution reaction(HER)performed with on-chip microdevices.Electrical and electrochemical measurement of individual flack verified the key role of high carrier mobility for enhanced HER activity.Carrier mobility regulation further demonstrated its high dependence with HER performance under self-gating.Our study provides new insight into the carrier mobility of the semiconductor in the electrocatalysis,paving the way for designing high-performance semiconductor catalysts. | Haiyan Xiang Yueshao Zheng Yang Chen Yanting Xu Travis Shihao Hu Yexin Feng Yu Zhou Song Liu Xuli Chen | 2022 | Chinese Chemical Letters2022，33，6： | 0 |
| 16 | How to Accelerate Radical Technological Innovation?——From the Perspective of Technology Management and Technological Capability显示文摘Due to the advantage of developing and bringing to innovative products ahead of competitors,the importance of radical technological innovation is well recognized.Based on the synergy theory,this study examines the effects of technology management(TM)and technological capability(TC)on radical technological innovation,and further explores the impact of the synergy between TM and TC on radical technological innovation.The results show that,firstly,both TM and TC have positive impacts on radical technological innovation,and thus two direct routines of radical technological innovation are identified.Secondly,the synergy between TM and TC also exerts positive impact on radical technological innovation,and this result indicates that the synergy between TM and TC plays an important role in radical technological innovation.This research provides a refreshing perspective on how to stimulate radical technological innovation,and also puts forward some beneficial suggestions for firms to improve radical technological innovation. | Yexin Liu Weiwei Wu | 2021 | 管理科学与研究(中英文版)2021，10，1： | 0 |
| 17 | Schisandra lignans ameliorate nonalcoholic steatohepatitis by regulating aberrant metabolism of phosphatidylethanolamines显示文摘Nonalcoholic steatohepatitis(NASH)is a spectrum of chronic liver disease characterized by hepatic lipid metabolism disorder.Recent reports emphasized the contribution of triglyceride and diglyceride accumulation to NASH,while the other lipids associated with the NASH pathogenesis remained unexplored.The specific purpose of our study was to explore a novel pathogenesis and treatment strategy of NASH via profiling the metabolic characteristics of lipids.Herein,multi-omics techniques based on LC—Q-TOF/MS,LC—MS/MS and MS imaging were developed and used to screen the action targets related to NASH progress and treatment.A methionine and choline deficient(MCD)diet-induced mouse model of NASH was then constructed,and Schisandra lignans extract(SLE)was applied to alleviate hepatic damage by regulating the lipid metabolism-related enzymes CES2A and CYP4A14.Hepatic lipidomics indicated that MCD-diet led to aberrant accumulation of phosphatidylethanolamines(PEs),and SLE could significantly reduce the accumulation of intrahepatic PEs.Notably,exogenous PE(18:0/18:1)was proved to significantly aggravate the mitochondrial damage and hepatocyte apoptosis.Supplementing PE(18:0/18:1)also deteriorated the NASH progress by up regulating intrahepatic proinflammatory and fibrotic factors,while PE synthase inhibitor exerted a prominent hepatoprotective role.The current work provides new insights into the relationship between PE metabolism and the pathogenesis of NASH. | Lijuan Xue Keanqi Liu Caixia Yan Junling Dun Yexin Xu Linlin Wu Huizhu Yang Huafang Liu Lin Xie Guangji Wang Yan Liang | 2023 | Acta Pharmaceutica Sinica B2023，13，8： | 0 |
| 18 | Role of ghrelin in cognitive impairment of hypertensive elders with chronic psychological distress显示文摘Objective:To investigate ghrelin level change in combination with psychological stress in the hypertensive old people with cognitive impairment and to explore its effect as well as possible mechanism.Methods:The study population of 300 elders was divided into 2 groups,148 with hypertension and 152 non-hypertension,who were screened for psychological distress and cognition function,and had blood drawn to measure plasma levels of ghrelin and total cortisol on the same day.Results:The rates of anxiety and cognitive impairment were higher in the hypertension elders,which were negatively correlated with plasma ghrelin level,resulted from chronic cortisol response to anxiety.Conclusion:Chronic plasma cortisol increase to long-term anxiety leads a reduce in ghrelin level which then adversely affects blood pressure and cognitive function in old people.So measuring ghrelin of elders may be a diagnostic tool to predict cognitive development and ghrelin may be a selective antihypertensive medicine for cognitive impairment elders with or without chronic psychological stress. | Zhang Yushun Fan Fenling Tian Hongyan Feng Jun Ma Xiancang Liu Yamin Hu Zhi Zhang Junbo Ma Yexin | 2010 | Journal of Medical Colleges of PLA(China)2010，25，3： | 0 |
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