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| 1 | Receiving response of towed line array to the noise of the tow ship in shallow water显示文摘The receiving response of towed line array to the noise radiated from the tow ship is investigated through normal mode modeling and computer simulation.The phenomenon that the maximum output of the towed line array is away from the endfire direction towards the tow ship is explained.The result is important for the understanding of the phenomenon and also for the application research concerning the suppression of the noise from the tow ship as well as adequate application of towed array techniques in shallow water. | MA Yuanliang LIU Mengan ZHANG Zhongbing TONG Li(1 Institute of Acoustic Engineering, Northwestern Polytechnical University Xi’an 710072) (2 Hangzhou Institute of Applied Acoustics Fuyang 311400) | 2003 | Chinese Journal of Acoustics2003，22，1： | 10 |
| 2 | Cotransport of graphene oxides/reduced graphene oxides with BPA in both bare and iron oxides coated quartz sand显示文摘This study investigated the cotransport behaviors of graphene oxides(GO) and reduced graphene oxides(RGO) with bisphenol A(BPA) in porous media in both NaCl(1 and 10 mmol/L) and CaCl2 solutions(0.5 and 1.5 mmol/L) at pH 6.5. Both bare and iron oxides-coated quartz sand were employed as porous media in present study. We found that under all examined solution conditions, the presence of BPA(100 μg/L) did not have obvious influence on the transport of both GO and RGO(8 mg/L as TOC) in both bare and iron oxides-coated quartz sand. Although the dissolved BPAwas the major form dominating the transport behaviors of total BPA in the presence of GO/RGO, yet the GO/RGO-associated BPA(due to the adsorption of BPA onto GO/RGO surfaces) also had some contribution to the transport of total BPA in the presence of GO/RGO in two types of porous media.Overall, due to the different transport behaviors of GO and RGO under different solution conditions, we found that the presence of GO/RGO decreased the transport of total BPA under all examined solution conditions in two types of porous media with the smallest decrease in 1 mmol/L NaCl solutions and the largest in 1.5 mmol/L CaCl2 solutions. The results of this study clearly indicated that when BPA was co-present with GO/RGO, the transport behaviors of GO/RGO in porous media would have great influences on the fate and transport of BPA in natural environments due to their adsorption onto GO/RGO. | LIU Xian Wei LI Meng LIU FuYang HE Lei TONG MeiPing | 2019 | Science China(Technological Sciences)2019，62，11： | 4 |
| 3 | Dopaminergic Neurons in the Ventral Tegmental–Prelimbic Pathway Promote the Emergence of Rats from Sevoflurane Anesthesia显示文摘Dopaminergic neurons in the ventral tegmental area(VTA)play an important role in cognition,emergence from anesthesia,reward,and aversion,and their projection to the cortex is a crucial part of the'bottom-up'ascending activating system.The prelimbic cortex(PrL)is one of the important projection regions of the VTA.However,the roles of dopaminergic neurons in the VTA and the VTADA–PrL pathway under sevoflurane anesthesia in rats remain unclear.In this study,we found that intraperitoneal injection and local microinjection of a dopamine D1 receptor agonist(Chloro-APB)into the PrL had an emergence-promoting effect on sevoflurane anesthesia in rats,while injection of a dopamine D1 receptor antagonist(SCH23390)deepened anesthesia.The results of chemogenetics combined with microinjection and optogenetics showed that activating the VTADA–PrL pathway prolonged the induction time and shortened the emergence time of anesthesia.These results demonstrate that the dopaminergic system in the VTA has an emergence-promoting effect and that the bottom-up VTADA–PrL pathway facilitates emergence from sevoflurane anesthesia. | Yanping Song Ruitong Chu Fuyang Cao Yanfeng Wang Yanhong Liu Jiangbei Cao Yongxin Guo Weidong Mi Li Tong | 2022 | Neuroscience Bulletin2022，38，4： | 3 |
| 4 | Functional Analysis of Discoidin Domain Receptor 2 in Synovial Fibroblasts in Rheumatoid Arthritis显示文摘 | Jicun Wang Houshan Lü Xinping Liu Yanchun Deng Tiezheng Sun Fuyang Li Shaoping Ji Xiaoyan Nie Libo Yao | 2002 | Journal of Autoimmunity2002，，3： | 1 |
| 5 | Tetrahedral framework nucleic acids promote the biological functions and related mechanism of synovium-derived mesenchymal stem cells and show improved articular cartilage regeneration activity in situ显示文摘Many recent studies have shown that joint-resident mesenchymal stem cells(MSCs)play a vital role in articular cartilage(AC)in situ regeneration.Specifically,synovium-derived MSCs(SMSCs),which have strong chondrogenic differentiation potential,may be the main driver of cartilage repair.However,both the insufficient number of MSCs and the lack of an ideal regenerative microenvironment in the defect area will seriously affect the regeneration of AC.Tetrahedral framework nucleic acids(tFNAs),notable novel nanomaterials,are considered prospective biological regulators in biomedical engineering.Here,we aimed to explore whether tFNAs have positive effects on AC in situ regeneration and to investigate the related mechanism.The results of in vitro experiments showed that the proliferation and migration of SMSCs were significantly enhanced by tFNAs.In addition,tFNAs,which were added to chondrogenic induction medium,were shown to promote the chondrogenic capacity of SMSCs by increasing the phosphorylation of Smad2/3.In animal models,the injection of tFNAs improved the therapeutic outcome of cartilage defects compared with that of the control treatments without tFNAs.In conclusion,this is the first report to demonstrate that tFNAs can promote the chondrogenic differentiation of SMSCs in vitro and enhance AC regeneration in vivo,indicating that tFNAs may become a promising therapeutic for AC regeneration. | Liwei Fu Pinxue Li Junyao Zhu Zhiyao Liao Cangjian Gao Hao Li Zhen Yang Tianyuan Zhao Wei Chen Yu Peng Fuyang Cao Chao Ning Xiang Sui Quanyi Guo Yunfeng Lin Shuyun Liu | 2022 | Bioactive Materials2022，7，3： | 1 |
| 6 | Methods for bearings-only underwater target motion analysis显示文摘The problem of estimation of underwater target motion parameters via bearings only is the most of ten encountered and most difficult to solve in the underwater target motion analysis.As the bearings-only target motion analysis is a nonlinear and multiextremal global optimization problem, so most classical estimation methods often lead the solution to convergence to one of the local extremes other than the global extreme, especially, when the noise of target bearing observation is added. In this paper we propose to use the Generalized Least Square method on the rough estimation of target motion parameters, and then use the Sequential Uniform Design method to gain a more precise estimation on the bases of rough estimation.The latter ensures that the result convergences to the global extreme. The algorithm based on the above two methods is profitable for the bearings-only target motion analysis even under conditions of large bearing observation error. | PAN Zhijian and YAN Fuwang (Marine Research Center, P.B. 1303-15 Beijing 100073)LIU Mengan and WANG Guangen (Applied Acoustics Institute, P.B. 1 Fuyang 311400) | 1997 | Chinese Journal of Acoustics1997，16，3： | 1 |
| 7 | Hot deformation behavior of spray-deposited Al–Zn–Mg–Cu alloy显示文摘 | Yandong Jia Fuyang Cao Shu Guo Pan Ma Jingshun Liu Jianfei Sun | 2013 | Materials and Design2013，，： | 1 |
| 8 | 尽快缩小电费占烧碱成本的比例显示文摘氯碱工业是耗电大户,近几年来由于供电价格不断上涨,加之氯碱企业吨碱电耗与国外先进国家存在着不小差距,因此使电费在氯碱成本中的比例越来越大,直接影响着企业的经济效益。采取有力措施,尽快扼制住这种发展趋势。 | Liu Zizhen (Fuyang Chemical Industry Group Co.Ltd.,Handan, 056003) | 1999 | 氯碱工业1999，0，3： | 1 |
| 9 | Effect of Yinlai Decoction on the metabolic pathways in the lung of high-calorie diet-induced pneumonia rats显示文摘Objective:To search for specific metabolites in the lungs of pneumonia rats fed with a high-calorie diet,as well as explore the changes in the lung metabolites of young rats treated with Yinlai Decoction(YD)and its effects on inflammation-related metabolic pathways.Methods:Lipopolysaccharides(LPS)and a special high-calorie diet were used to induce Sprague Dawley(SD)rats to simulate the intestinal state of infant pneumonia.Liquid chromatography-mass spectrometry technology(LC-MS/MS)was used to detect metabolites in each group.Supervised orthogonal partial least squares discriminant analysis(OPLS-DA)model values were used for the detection results to find the differential metabolites.The metabolic pathways that are involved with the differential metabolites were clarified through enrichment analysis and topological analysis.Finally,the T cell receptor signaling pathway(TCR)signal conversion was analyzed by the network pharmacology method.Results:In the high-calorie diet combined with pneumonia group(M3),a total of 55 metabolites were determined to be different from the normal group(N).A total of 36 metabolites were determined to be different from those in the lung metabolites of the YD treatment group(T1).YD had a regulatory effect on glutathione metabolism,arginine and proline metabolism,ascorbic acid and aldehyde metabolism and phenylalanine metabolism.And the small molecule metabolites could act on the FYN and lymphocytespecific protein tyrosine kinase(LCK)target proteins in the TCR signaling pathway,thereby affecting the immune function of the lungs.Conclusion:A high-calorie diet can cause abnormal sphingolipid metabolism in the lungs of young rats,thereby creating chronic lung inflammation in young rats.YD has a beneficial effect when used to treat young rats with LPS-induced pneumonia fed on high-calorie diets.Its mechanisms of action may affect the body’s immune pathways by regulating the oxidative stress pathway affected by glutathione metabolism. | Fuyang Xian Tiegang Liu Chen Bai Guannan Yang Xueyan Ma Bochuan Wang Ling Huang Shaoyang Liu Jianhua Zhen Jianzhen He He Yu Yuling Ma Taiyi Wang Xiaohong Gu | 2021 | Journal of Traditional Chinese Medical Sciences2021，8，1： | 1 |
| 10 | Negative Magnetism in Perovskite Manganites Gd1-xSrxMnO3(0.1 ≤x≤0.3)显示文摘 | ZHANG Yingnan LI Junjia ZHANG Ziqing LIU Fuyang ZHAO Xudong LIU Xiaoyang | 2015 | Chemical Research in Chinese Universities2015，31，5： | 0 |
| 11 | Pressure-driven symmetry breaking and electron disproportionation of the trigonal Nb_(3)cluster in Nb_(3)Cl_(8)显示文摘Symmetry breaking of metal cluster-based strongly correlated systems can give rise to collective phenomena.Here,the twodimensional Nb_(3) cluster compound Nb_(3)Cl_(8) is shown to suffer dramatic symmetry breaking and electron disproportionation under compression.A structural phase transition from trigonal P–3m1 to monoclinic C2/m is observed near 8 GPa with the three-fold symmetry breaking.Electron disproportionation occurs on Nb_(3) clusters from delocalized Nb^(8/3+)Nb^(8/3+)Nb^(8/3+)to localized Nb^(3+)Nb^(3+)Nb^(2+),which results in a subtle bandgap discontinuity,as evidenced by electrical transport and UV-Vis absorption measurements. | Zimin Jiang Dequan Jiang Yiming Wang Chen Li Ke Liu Ting Wen Fuyang Liu Zhengyang Zhou Yonggang Wang | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，7： | 0 |
| 12 | Novel biomarkers identifying hypertrophic cardiomyopathy and its obstructive variant based on targeted amino acid metabolomics显示文摘Background:Hypertrophic cardiomyopathy(HCM)is an underdiagnosed genetic heart disease worldwide.The management and prognosis of obstructive HCM(HOCM)and non-obstructive HCM(HNCM)are quite different,but it also remains challenging to discriminate these two subtypes.HCM is characterized by dysmetabolism,and myocardial amino acid(AA)metabolism is robustly changed.The present study aimed to delineate plasma AA and derivatives profiles,and identify potential biomarkers for HCM.Methods:Plasma samples from 166 participants,including 57 cases of HOCM,52 cases of HNCM,and 57 normal controls(NCs),who first visited the International Cooperation Center for HCM,Xijing Hospital between December 2019 and September 2020,were collected and analyzed by high-performance liquid chromatography-mass spectrometry based on targeted AA metabolomics.Three separate classification algorithms,including random forest,support vector machine,and logistic regression,were applied for the identification of specific AA and derivatives compositions for HCM and the development of screening models to discriminate HCM from NC as well as HOCM from HNCM.Results:The univariate analysis showed that the serine,glycine,proline,citrulline,glutamine,cystine,creatinine,cysteine,choline,and aminoadipic acid levels in the HCM group were significantly different from those in the NC group.Four AAs and derivatives(Panel A;proline,glycine,cysteine,and choline)were screened out by multiple feature selection algorithms for discriminating HCM patients from NCs.The receiver operating characteristic(ROC)analysis in Panel A yielded an area under the ROC curve(AUC)of 0.83(0.75-0.91)in the training set and 0.79(0.65-0.94)in the validation set.Moreover,among 10 AAs and derivatives(arginine,phenylalanine,tyrosine,proline,alanine,asparagine,creatine,tryptophan,ornithine,and choline)with statistical significance between HOCM and HNCM,3 AAs(Panel B;arginine,proline,and ornithine)were selected to differentiate the two subgroups.The AUC values in the training and validation sets for Panel B were 0.83(0.74-0.93)and 0.82(0.66-0.98),respectively.Conclusions:The plasma AA and derivatives profiles were distinct between the HCM and NC groups.Based on the differential profiles,the two established screening models have potential value in assisting HCM screening and identifying whether it is obstructive. | Lanyan Guo Bo Wang Fuyang Zhang Chao Gao Guangyu Hu Mengyao Zhou Rutao Wang Hang Zhao Wenjun Yan Ling Zhang Zhiling Ma Weiping Yang Xiong Guo Chong Huang Zhe Cui Fangfang Sun Dandan Song Liwen Liu Ling Tao | 2022 | Chinese Medical Journal2022，135，16： | 0 |
| 13 | Ferroelectricity induced by non-symmetry of A-site cations in hexagonal antiferromagnetic In_(1-x)Yb_(x)FeO_(3)(x=0.1,0.2,0.3) perovskites显示文摘A new series of multiferroic In_(1-x)Yb_(x)FeO_(3)(x=0.1,0.2,0.3) compounds were prepared using the traditional synthesis method for the first time.Partially substituting In ions in InFeO3with Yb ions results in the weak ferroelectricity of the compound.A dielectric relaxation peak is found at ~500 K in the temperature dependence of the dielectric properties of the resulted compounds.The dielectric constant of In_(0.8)Yb_(0.2)FeO_(3)displays an anomaly at -500 K,and the ferroelectric hysteresis loop reveals its weak ferroelectric behaviors below this temperature.Similarly to InFeO_(3),the compounds crystallize in space group P63/mmc.The increase in the Yb content leads to an increment in a and a reduction in c parameters.The temperature dependence of magnetization for In_(0.8)Yb_(0.2)FeO_(3)gives a Néel temperature of -150 K.The hysteresis loops at 10 and 100 K indicate its weak ferromagnetic characteristics above room temperature.Thus,In_(1-x)Yb_(x)FeO_(3)(x=0.1,0.2,0.3) compounds show both weak ferroelectricity and weak ferromagnetism.The non-symmetry of Yb cations causes the ferroelectricity of the compounds. | Yong Zhou Peng Liu Yang Chen Bin Yang Bing Li Fuyang Liu Xiaoyang Liu | 2023 | Journal of Rare Earths2023，41，12： | 0 |
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